| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.123813 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.120276 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.105159 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.101977 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0886792 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0807399 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0790525 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0720585 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0686723 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0684435 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0648561 |
| APP | amyloid beta (A4) precursor protein | 0.0634747 |
| TMSB4X | thymosin beta 4, X-linked | 0.0611221 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0606594 |
| RIOK3 | RIO kinase 3 | 0.0588684 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0586756 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0577414 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0577231 |
| GLCCI1 | glucocorticoid induced 1 | 0.0541313 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0537587 |
| NTN4 | netrin 4 | 0.0526732 |
| KYNU | kynureninase | 0.0520181 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0519934 |
| RAI14 | retinoic acid induced 14 | 0.0517339 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0516162 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0515059 |
| ATP13A3 | ATPase type 13A3 | 0.0509633 |
| RPL3 | ribosomal protein L3 | 0.0507931 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0503072 |
| ADM | adrenomedullin | 0.0496942 |
| B2M | beta-2-microglobulin | 0.0488312 |
| STC1 | stanniocalcin 1 | 0.048701 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0480813 |
| SMAD3 | SMAD family member 3 | 0.0476825 |
| SFTPA2 | surfactant protein A2 | 0.0462512 |
| PGK1 | phosphoglycerate kinase 1 | 0.0451358 |
| PTMA | prothymosin, alpha | 0.0443683 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0439315 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0437285 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0426549 |
| CPNE1 | copine I | 0.0425689 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0420874 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0419773 |
| PCBP2 | poly(rC) binding protein 2 | 0.0400558 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0382252 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0378609 |
| CANX | calnexin | 0.0377233 |
| RNF24 | ring finger protein 24 | 0.0371892 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0369324 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0368726 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0365379 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0364758 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0363211 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0363064 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0361688 |
| COPA | coatomer protein complex, subunit alpha | 0.0360222 |
| CALR | calreticulin | 0.0360213 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0358153 |
| OPTN | optineurin | 0.035637 |
| ENO1 | enolase 1, (alpha) | 0.0351352 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0350599 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0347827 |
| KSR1 | kinase suppressor of ras 1 | 0.03475 |
| ECE1 | endothelin converting enzyme 1 | 0.0344119 |
| PRRC2C | proline-rich coiled-coil 2C | 0.034156 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0338945 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0336951 |
| CALU | calumenin | 0.0335246 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.033381 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.033365 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0329819 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0323465 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0318876 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0306302 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0303421 |
| SSH2 | slingshot protein phosphatase 2 | 0.0302124 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0302101 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0300715 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0298701 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0294158 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0286989 |
| GOLGA3 | golgin A3 | 0.0286108 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0285723 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0284295 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0284153 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0283833 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0282812 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0282554 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0279908 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0278655 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0277654 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0276372 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0275714 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0274391 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0274114 |
| SPAG9 | sperm associated antigen 9 | 0.0273472 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0273178 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0271642 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0269647 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0268116 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.156031 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.134449 |
| NDRG1 | N-myc downstream regulated 1 | -0.108741 |
| CDH13 | cadherin 13 | -0.0879798 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0783685 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0782965 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0736551 |
| EFNA5 | ephrin-A5 | -0.0712289 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0601191 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0595707 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0587441 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0585387 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0580031 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0561156 |
| MEF2A | myocyte enhancer factor 2A | -0.0554339 |
| HMGA1 | high mobility group AT-hook 1 | -0.0526171 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0488105 |
| RAD51B | RAD51 paralog B | -0.0478803 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0475888 |
| HMGA2 | high mobility group AT-hook 2 | -0.0445596 |
| LOX | lysyl oxidase | -0.0438651 |
| USP34 | ubiquitin specific peptidase 34 | -0.0429966 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0420012 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.041048 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.039965 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0383043 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0375957 |
| GPC6 | glypican 6 | -0.0371721 |
| TMEM165 | transmembrane protein 165 | -0.0371424 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0342202 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0342083 |
| TNNC1 | troponin C type 1 (slow) | -0.0341815 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0336339 |
| NHSL1 | NHS-like 1 | -0.0321681 |
| POTEF | POTE ankyrin domain family, member F | -0.0312986 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0298834 |
| ZNF804A | zinc finger protein 804A | -0.0275623 |
| RPL9 | ribosomal protein L9 | -0.0275478 |
| RBM39 | RNA binding motif protein 39 | -0.0272705 |
| NBAS | neuroblastoma amplified sequence | -0.0271945 |
| CDCP1 | CUB domain containing protein 1 | -0.0270446 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0270217 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0268435 |
| DTNA | dystrobrevin, alpha | -0.0265781 |
| PRELID2 | PRELI domain containing 2 | -0.0262715 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0261436 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.02598 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0259772 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0258142 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0257575 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0251056 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0249492 |
| IFI44L | interferon-induced protein 44-like | -0.0249154 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0247896 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0247684 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0243517 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0242129 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0240569 |
| SLC43A3 | solute carrier family 43, member 3 | -0.0239833 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.023947 |
| LRRC49 | leucine rich repeat containing 49 | -0.0238817 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0238528 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0237072 |
| CD109 | CD109 molecule | -0.023633 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.023515 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0229652 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0225487 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0225082 |
| DNER | delta/notch-like EGF repeat containing | -0.0221628 |
| RPL28 | ribosomal protein L28 | -0.0221193 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0218083 |
| CFAP20DC | CFAP20 domain containing | -0.0218011 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0215189 |
| NGLY1 | N-glycanase 1 | -0.0215071 |
| VEGFA | vascular endothelial growth factor A | -0.0214619 |
| CA12 | carbonic anhydrase XII | -0.021384 |
| CCDC91 | coiled-coil domain containing 91 | -0.0212055 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0211481 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0208429 |
| RPL35A | ribosomal protein L35a | -0.0208145 |
| RPS6 | ribosomal protein S6 | -0.0206847 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0203061 |
| OXR1 | oxidation resistance 1 | -0.0202943 |
| PTK2 | protein tyrosine kinase 2 | -0.0200554 |
| ANXA2 | annexin A2 | -0.0200096 |
| HDAC4 | histone deacetylase 4 | -0.0200049 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0197835 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0197702 |
| HDAC9 | histone deacetylase 9 | -0.0195787 |
| SMYD3 | SET and MYND domain containing 3 | -0.0195638 |
| RARB | retinoic acid receptor, beta | -0.0194436 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0193732 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0192487 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0190686 |
| PTEN | phosphatase and tensin homolog | -0.0190536 |
| LOXL2 | lysyl oxidase-like 2 | -0.0185411 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0181882 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0181188 |
| WWOX | WW domain containing oxidoreductase | -0.0181042 |
| NAV2 | neuron navigator 2 | -0.0180428 |
