| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Uridine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.153786 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.126395 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.122186 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.121722 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.106624 |
| ASPH | aspartate beta-hydroxylase | 0.0952612 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0900493 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0867179 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.086614 |
| TPM3 | tropomyosin 3 | 0.0865516 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0840559 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.081088 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0776429 |
| APP | amyloid beta (A4) precursor protein | 0.0770764 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0767174 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0744036 |
| TXNRD1 | thioredoxin reductase 1 | 0.0730499 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0728278 |
| RPL3 | ribosomal protein L3 | 0.0713184 |
| PTMA | prothymosin, alpha | 0.0689289 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0672176 |
| CALR | calreticulin | 0.066143 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0622665 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0614726 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0601795 |
| RPS2 | ribosomal protein S2 | 0.0599326 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0583678 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0558429 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0539624 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0537208 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0535443 |
| RPL4 | ribosomal protein L4 | 0.0534425 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0534082 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0514498 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.051058 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0501967 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0491008 |
| PFDN2 | prefoldin subunit 2 | 0.0470043 |
| TMSB4X | thymosin beta 4, X-linked | 0.0460275 |
| LMNA | lamin A/C | 0.0440408 |
| CAVIN1 | caveolae associated protein 1 | 0.0440292 |
| YME1L1 | YME1-like 1 ATPase | 0.0436973 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0434905 |
| HDAC9 | histone deacetylase 9 | 0.0426952 |
| HDGF | hepatoma-derived growth factor | 0.0422019 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.041831 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0406068 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0404009 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0402588 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.039915 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0397023 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.039468 |
| MSN | moesin | 0.0394459 |
| FAM107B | family with sequence similarity 107, member B | 0.0394096 |
| TPI1 | triosephosphate isomerase 1 | 0.0392697 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0382427 |
| SET | SET nuclear proto-oncogene | 0.0382086 |
| RAB10 | RAB10, member RAS oncogene family | 0.0377527 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0375579 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0374366 |
| CALU | calumenin | 0.0371888 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0362323 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0362317 |
| AHNAK | AHNAK nucleoprotein | 0.0359561 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0351784 |
| ENO1 | enolase 1, (alpha) | 0.0351692 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0347391 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0347166 |
| SFTPA2 | surfactant protein A2 | 0.0344821 |
| PKM | pyruvate kinase, muscle | 0.0342724 |
| STC1 | stanniocalcin 1 | 0.0342471 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0340525 |
| GRAMD1B | GRAM domain containing 1B | 0.0339905 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0337817 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0335321 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0332513 |
| HYOU1 | hypoxia up-regulated 1 | 0.0331255 |
| CYRIB | CYFIP related Rac1 interactor B | 0.032863 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0315231 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0309945 |
| SEPTIN7 | septin 7 | 0.0307691 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0306338 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0305832 |
| DST | dystonin | 0.0301422 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0297571 |
| CPNE1 | copine I | 0.0295054 |
| NCKAP1 | NCK-associated protein 1 | 0.0294212 |
| ANXA1 | annexin A1 | 0.0293659 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.029361 |
| COPA | coatomer protein complex, subunit alpha | 0.029164 |
| CANX | calnexin | 0.0291152 |
| TPM4 | tropomyosin 4 | 0.0285739 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0283059 |
| ACTN1 | actinin, alpha 1 | 0.0280053 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0279609 |
| TNPO1 | transportin 1 | 0.0279018 |
| MKI67 | marker of proliferation Ki-67 | 0.0278989 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0277749 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0274384 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.027355 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.365455 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.181786 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.155459 |
| FTL | ferritin, light polypeptide | -0.0975551 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0726843 |
| IGF2 | insulin-like growth factor 2 | -0.0653912 |
| POTEF | POTE ankyrin domain family, member F | -0.058941 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0558611 |
| HMGA1 | high mobility group AT-hook 1 | -0.0516747 |
| EGR1 | early growth response 1 | -0.0478036 |
| NRG1 | neuregulin 1 | -0.0470305 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0425373 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0395168 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0394253 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0389197 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0382773 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0382182 |
| RPLP1 | ribosomal protein, large, P1 | -0.0363569 |
| DOCK4 | dedicator of cytokinesis 4 | -0.035551 |
| PDE8A | phosphodiesterase 8A | -0.0348033 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0341369 |
| WWOX | WW domain containing oxidoreductase | -0.0337512 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0325221 |
| NAV3 | neuron navigator 3 | -0.0316519 |
| PARD3 | par-3 family cell polarity regulator | -0.0316119 |
| GLIS3 | GLIS family zinc finger 3 | -0.0305192 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0301622 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0291126 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0284858 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0274769 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0273761 |
| EFNA5 | ephrin-A5 | -0.0265416 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0264095 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0258178 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0254567 |
| RPL9 | ribosomal protein L9 | -0.0254528 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0251304 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0245749 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0244342 |
| PFN1 | profilin 1 | -0.0244177 |
| RPS12 | ribosomal protein S12 | -0.0242731 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0241525 |
| BICC1 | BicC family RNA binding protein 1 | -0.0236678 |
| RPL30 | ribosomal protein L30 | -0.0228362 |
| RPS6 | ribosomal protein S6 | -0.0228315 |
| TUBA1B | tubulin, alpha 1b | -0.0227953 |
| RPL28 | ribosomal protein L28 | -0.0224949 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0224018 |
| RSF1 | remodeling and spacing factor 1 | -0.0218968 |
| RPL35A | ribosomal protein L35a | -0.0214287 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0211302 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0208557 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0208331 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.020344 |
| VIM | vimentin | -0.0203405 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0201299 |
| NDRG1 | N-myc downstream regulated 1 | -0.0199903 |
| OSMR | oncostatin M receptor | -0.0197911 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0196326 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0195977 |
| LAMA5 | laminin, alpha 5 | -0.0195533 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0193436 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0190347 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0190007 |
| TAGLN2 | transgelin 2 | -0.0189862 |
| AK1 | adenylate kinase 1 | -0.0183189 |
| RBM25 | RNA binding motif protein 25 | -0.0182409 |
| IL6 | interleukin 6 | -0.0181566 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0180651 |
| BSG | basigin (Ok blood group) | -0.0179054 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0175586 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0174907 |
| NEBL | nebulette | -0.017464 |
| MT2A | metallothionein 2A | -0.0173805 |
| CCNK | cyclin K | -0.0171748 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0171318 |
| RPS24 | ribosomal protein S24 | -0.0170698 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0168914 |
| SNX14 | sorting nexin 14 | -0.0168702 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0167972 |
| RNF11 | ring finger protein 11 | -0.0167417 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0167353 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0164981 |
| RPL39 | ribosomal protein L39 | -0.0162856 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0162696 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0162341 |
| CABIN1 | calcineurin binding protein 1 | -0.0161344 |
| TMSB10 | thymosin beta 10 | -0.016123 |
| JUP | junction plakoglobin | -0.0160359 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0159151 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0158345 |
| MYADM | myeloid-associated differentiation marker | -0.01568 |
| HMGA2 | high mobility group AT-hook 2 | -0.0156369 |
| FOSL1 | FOS-like antigen 1 | -0.0155268 |
| XDH | xanthine dehydrogenase | -0.015436 |
| PHIP | pleckstrin homology domain interacting protein | -0.0153179 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0152821 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0151088 |
| RSPO3 | R-spondin 3 | -0.0148845 |
| SEC24A | SEC24 family member A | -0.014813 |
