| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Uridine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT17 | keratin 17, type I | 0.141465 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.130237 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.119148 |
| NDRG1 | N-myc downstream regulated 1 | 0.105017 |
| FN1 | fibronectin 1 | 0.103354 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.10221 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0870669 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0836588 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0781431 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0750974 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0690628 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.068999 |
| S100A9 | S100 calcium binding protein A9 | 0.0687983 |
| SETD5 | SET domain containing 5 | 0.0665643 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0648217 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0647149 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0639414 |
| MT2A | metallothionein 2A | 0.0619586 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0616695 |
| PTMA | prothymosin, alpha | 0.0594154 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.059414 |
| MCL1 | myeloid cell leukemia 1 | 0.0583385 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0570048 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0503011 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0501916 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0498635 |
| FRY | furry homolog (Drosophila) | 0.0495882 |
| PKM | pyruvate kinase, muscle | 0.049545 |
| CSTB | cystatin B (stefin B) | 0.0485937 |
| CXXC1 | CXXC finger protein 1 | 0.0478418 |
| NABP1 | nucleic acid binding protein 1 | 0.0462866 |
| FLNB | filamin B, beta | 0.0460157 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0451159 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0450489 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0447965 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0445278 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0442502 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.04353 |
| ZNF207 | zinc finger protein 207 | 0.0426581 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0422505 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0420894 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0417122 |
| LAMC2 | laminin, gamma 2 | 0.0415016 |
| KYNU | kynureninase | 0.0413844 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0408074 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.039755 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0394461 |
| PDE10A | phosphodiesterase 10A | 0.0390256 |
| PGK1 | phosphoglycerate kinase 1 | 0.0389879 |
| SEPTIN9 | septin 9 | 0.0386767 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0377052 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0371999 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0371354 |
| ANXA2 | annexin A2 | 0.0364679 |
| ACTN4 | actinin, alpha 4 | 0.0362467 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0357986 |
| SEPTIN7 | septin 7 | 0.0356854 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0354441 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0352552 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0352475 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0351358 |
| ATP13A3 | ATPase type 13A3 | 0.0342961 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0341781 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0341437 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0334306 |
| RUNX1 | runt-related transcription factor 1 | 0.0329772 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0327136 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0325236 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0324212 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0324101 |
| TXNIP | thioredoxin interacting protein | 0.0320858 |
| STEAP4 | STEAP family member 4 | 0.0317511 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0314515 |
| PCBP2 | poly(rC) binding protein 2 | 0.0314079 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0314047 |
| RPS12 | ribosomal protein S12 | 0.0313285 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0312295 |
| SMAD3 | SMAD family member 3 | 0.0304937 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0303307 |
| EZR | ezrin | 0.0300825 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0292918 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0290444 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0288786 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0288701 |
| WDR26 | WD repeat domain 26 | 0.0285048 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0282384 |
| FAM13A | family with sequence similarity 13, member A | 0.0281205 |
| WDR45B | WD repeat domain 45B | 0.0280283 |
| PRELID2 | PRELI domain containing 2 | 0.0278551 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.027831 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0277485 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0274501 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0271808 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0269564 |
| ARRDC3 | arrestin domain containing 3 | 0.0266875 |
| KIF5B | kinesin family member 5B | 0.0263995 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0263052 |
| STK24 | serine/threonine kinase 24 | 0.0262259 |
| DSPP | dentin sialophosphoprotein | 0.0259218 |
| ETV6 | ets variant 6 | 0.0257542 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFIH1 | interferon induced with helicase C domain 1 | -0.142708 |
| SPAG9 | sperm associated antigen 9 | -0.0936812 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0936251 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0788639 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0783622 |
| RIGI | RNA sensor RIG-I | -0.0767585 |
| MUC16 | mucin 16, cell surface associated | -0.0740291 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0678278 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0652396 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0648858 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0619976 |
| B2M | beta-2-microglobulin | -0.0590631 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0584034 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0581778 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0538665 |
| COPA | coatomer protein complex, subunit alpha | -0.0536394 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.052399 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0523646 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0511275 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0508054 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0470522 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0464785 |
| SVIL | supervillin | -0.0451585 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0443344 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0431997 |
| SQSTM1 | sequestosome 1 | -0.0431789 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0430496 |
| NF1 | neurofibromin 1 | -0.0418523 |
| PAPOLA | poly(A) polymerase alpha | -0.0414377 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0410544 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0409452 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0406756 |
| MYO1E | myosin IE | -0.0405623 |
| FBXO11 | F-box protein 11 | -0.039809 |
| NEK7 | NIMA-related kinase 7 | -0.0392477 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0389823 |
| COG5 | component of oligomeric golgi complex 5 | -0.038723 |
| RNF149 | ring finger protein 149 | -0.0386294 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0384964 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0378075 |
| LMO7 | LIM domain 7 | -0.0373725 |
| MFSD14A | major facilitator superfamily domain containing 14A | -0.0373684 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0372562 |
| FOXP1 | forkhead box P1 | -0.0371904 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0371498 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0366271 |
| ZNF451 | zinc finger protein 451 | -0.0365711 |
| TJP1 | tight junction protein 1 | -0.0364836 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0364123 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0361401 |
| NRG1 | neuregulin 1 | -0.0357549 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0343601 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0342181 |
| PTEN | phosphatase and tensin homolog | -0.0342156 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0342148 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0339094 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0335684 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0335228 |
| ATXN1 | ataxin 1 | -0.0334812 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0334732 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0331532 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0331454 |
| CCDC6 | coiled-coil domain containing 6 | -0.0329254 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0327896 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0327708 |
| FAT1 | FAT atypical cadherin 1 | -0.0327689 |
| ADAR | adenosine deaminase, RNA-specific | -0.0327384 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0321743 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0321656 |
| GOLGB1 | golgin B1 | -0.0321155 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.031685 |
| SLMAP | sarcolemma associated protein | -0.031645 |
| NKTR | natural killer cell triggering receptor | -0.0315653 |
| MRTFA | myocardin related transcription factor A | -0.0315099 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0314314 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0312929 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0312874 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0311412 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0307438 |
| DST | dystonin | -0.0304211 |
| FTO | fat mass and obesity associated | -0.0303239 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0302554 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0301985 |
| USP6NL | USP6 N-terminal like | -0.0301907 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0294953 |
| SLC38A1 | solute carrier family 38, member 1 | -0.029352 |
| AHNAK | AHNAK nucleoprotein | -0.0292942 |
| ATP11B | ATPase, class VI, type 11B | -0.0290221 |
| NBEAL1 | neurobeachin-like 1 | -0.0285393 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0283853 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0278211 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0277093 |
| ZNF609 | zinc finger protein 609 | -0.0276669 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0275035 |
| MED13L | mediator complex subunit 13-like | -0.0274608 |
| CREBBP | CREB binding protein | -0.0274597 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0274482 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0271784 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0270844 |
| EGFR | epidermal growth factor receptor | -0.0270229 |
