| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Uridine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.210801 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.20477 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.178899 |
| LAMC2 | laminin, gamma 2 | 0.170695 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.137736 |
| TMSB4X | thymosin beta 4, X-linked | 0.130394 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.125919 |
| ASPH | aspartate beta-hydroxylase | 0.107144 |
| LAMB3 | laminin, beta 3 | 0.0958135 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0871399 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0852245 |
| DSPP | dentin sialophosphoprotein | 0.0838721 |
| CALR | calreticulin | 0.0815357 |
| PLEC | plectin | 0.0785675 |
| HMGB2 | high mobility group box 2 | 0.0760889 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0721634 |
| SDC4 | syndecan 4 | 0.0669922 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0630115 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0626348 |
| PTMA | prothymosin, alpha | 0.0614851 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0609273 |
| PGK1 | phosphoglycerate kinase 1 | 0.0558181 |
| MSN | moesin | 0.0549887 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0549693 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0534668 |
| FN1 | fibronectin 1 | 0.0497741 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0494024 |
| AHNAK | AHNAK nucleoprotein | 0.0492908 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0489175 |
| CANX | calnexin | 0.0487035 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0469204 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0467018 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0443895 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0441755 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0423657 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0406639 |
| LMO7 | LIM domain 7 | 0.0401286 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0393082 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0366096 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.035813 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0347605 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0342855 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0337247 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.033585 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.033077 |
| APP | amyloid beta (A4) precursor protein | 0.0322905 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0317587 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.031532 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.030732 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0306481 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0300887 |
| CTSB | cathepsin B | 0.029564 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0295276 |
| SFTPA2 | surfactant protein A2 | 0.0282261 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0277081 |
| ENO1 | enolase 1, (alpha) | 0.0271901 |
| OGA | O-GlcNAcase | 0.027084 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0267489 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0264377 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0259118 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0257328 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0256277 |
| RPL3 | ribosomal protein L3 | 0.0255066 |
| MYO5B | myosin VB | 0.024996 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0249233 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0249051 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0248159 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0246713 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0246551 |
| NAV2 | neuron navigator 2 | 0.0246094 |
| ANLN | anillin, actin binding protein | 0.0246071 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0245804 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0243841 |
| H1-4 | H1.4 linker histone, cluster member | 0.0239927 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0239734 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0239248 |
| RPL4 | ribosomal protein L4 | 0.0238145 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0238056 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0237442 |
| KLC1 | kinesin light chain 1 | 0.0236786 |
| EZR | ezrin | 0.0236337 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0234444 |
| CTTN | cortactin | 0.0230605 |
| SQSTM1 | sequestosome 1 | 0.0228892 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0228713 |
| TPI1 | triosephosphate isomerase 1 | 0.022507 |
| HDLBP | high density lipoprotein binding protein | 0.0224681 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0222153 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0221844 |
| CALU | calumenin | 0.022173 |
| CLDN12 | claudin 12 | 0.0219521 |
| MT2A | metallothionein 2A | 0.0219139 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0218851 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0216895 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0216607 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0212307 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0212015 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0211822 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0207321 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0207248 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.255822 |
| NDRG1 | N-myc downstream regulated 1 | -0.144766 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.144188 |
| HMGA1 | high mobility group AT-hook 1 | -0.128144 |
| FTL | ferritin, light polypeptide | -0.0770122 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0711145 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.068919 |
| TMSB10 | thymosin beta 10 | -0.058178 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0575116 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0534935 |
| RPLP1 | ribosomal protein, large, P1 | -0.0522445 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0516916 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0503281 |
| RPL30 | ribosomal protein L30 | -0.0493362 |
| RPL9 | ribosomal protein L9 | -0.0485509 |
| RPL35A | ribosomal protein L35a | -0.0455604 |
| ANXA2 | annexin A2 | -0.0454618 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0454404 |
| PTK2 | protein tyrosine kinase 2 | -0.0451193 |
| RACK1 | receptor for activated C kinase 1 | -0.044541 |
| ZNF292 | zinc finger protein 292 | -0.0437465 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0383171 |
| RNF145 | ring finger protein 145 | -0.038217 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0382046 |
| RPS6 | ribosomal protein S6 | -0.0373001 |
| CLDN4 | claudin 4 | -0.0347779 |
| FOSL1 | FOS-like antigen 1 | -0.0347071 |
| CCND1 | cyclin D1 | -0.034427 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0341225 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0339118 |
| EGR1 | early growth response 1 | -0.0336612 |
| KRT7 | keratin 7, type II | -0.0328932 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0328571 |
| DTNA | dystrobrevin, alpha | -0.0326046 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0316377 |
| RPL28 | ribosomal protein L28 | -0.0315512 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0315011 |
| LDHA | lactate dehydrogenase A | -0.0310682 |
| YBX1 | Y box binding protein 1 | -0.0309814 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0307355 |
| PCBP2 | poly(rC) binding protein 2 | -0.0303692 |
| TAPBP | TAP binding protein (tapasin) | -0.0301495 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.030034 |
| TMEM165 | transmembrane protein 165 | -0.0297458 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0292675 |
| RPS8 | ribosomal protein S8 | -0.029097 |
| USP3 | ubiquitin specific peptidase 3 | -0.0282265 |
| RHOA | ras homolog family member A | -0.0275382 |
| RPS23 | ribosomal protein S23 | -0.0272373 |
| RPS25 | ribosomal protein S25 | -0.0271362 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0269943 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0267491 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0266631 |
| S100A6 | S100 calcium binding protein A6 | -0.0265926 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0265816 |
| WASF2 | WAS protein family, member 2 | -0.0259834 |
| RPL27A | ribosomal protein L27a | -0.0256257 |
| ERBIN | erbb2 interacting protein | -0.0247896 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0242049 |
| JUP | junction plakoglobin | -0.0237897 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0235466 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0233182 |
| RPS12 | ribosomal protein S12 | -0.0232008 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0231458 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0230838 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0229903 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0227016 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0226377 |
| SEC24D | SEC24 family member D | -0.0225057 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0220699 |
| PFN1 | profilin 1 | -0.0220168 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0217688 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0217533 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0217183 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.021539 |
| DHFR | dihydrofolate reductase | -0.0213961 |
| COPA | coatomer protein complex, subunit alpha | -0.0212126 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.021132 |
| AGRN | agrin | -0.0208693 |
| RPS13 | ribosomal protein S13 | -0.0207758 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0207669 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0206436 |
| TFG | TRK-fused gene | -0.0206408 |
| TRAM1 | translocation associated membrane protein 1 | -0.0204181 |
| FBXO11 | F-box protein 11 | -0.0204181 |
| RPL37 | ribosomal protein L37 | -0.0203884 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0199909 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0197699 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0195348 |
| RPL11 | ribosomal protein L11 | -0.0195341 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0194564 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0193633 |
| TAGLN2 | transgelin 2 | -0.0193313 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0192378 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.0191886 |
| RAI14 | retinoic acid induced 14 | -0.019097 |
| RCOR1 | REST corepressor 1 | -0.0187535 |
| RPL5 | ribosomal protein L5 | -0.0187449 |
| PLSCR1 | phospholipid scramblase 1 | -0.0187118 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0185798 |
