| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.225084 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.207909 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.145888 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.131472 |
| TMSB4X | thymosin beta 4, X-linked | 0.121363 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.116275 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.11556 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.107223 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.102011 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0978972 |
| COL5A2 | collagen, type V, alpha 2 | 0.0888578 |
| DST | dystonin | 0.087613 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0862734 |
| PEG10 | paternally expressed 10 | 0.0851514 |
| PTMA | prothymosin, alpha | 0.0850038 |
| CALR | calreticulin | 0.0830673 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0741693 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0731418 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0710132 |
| H1-4 | H1.4 linker histone, cluster member | 0.0693659 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0669767 |
| EMP1 | epithelial membrane protein 1 | 0.0667581 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0633122 |
| THBS1 | thrombospondin 1 | 0.0632358 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0610656 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0602617 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.057073 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.056511 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0562849 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0529563 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0522394 |
| APP | amyloid beta (A4) precursor protein | 0.0506405 |
| ANXA1 | annexin A1 | 0.0501965 |
| RPL3 | ribosomal protein L3 | 0.047961 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0474325 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0467718 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0465907 |
| PHIP | pleckstrin homology domain interacting protein | 0.046147 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.044725 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0442325 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0439115 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0434991 |
| XPO1 | exportin 1 | 0.0428992 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0427688 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0423929 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0422738 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0417909 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0415893 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.041082 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0402569 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0397832 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0391026 |
| NFIA | nuclear factor I/A | 0.0385813 |
| RPS2 | ribosomal protein S2 | 0.0383442 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0379101 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0376702 |
| PLPP1 | phospholipid phosphatase 1 | 0.0372835 |
| SYT1 | synaptotagmin I | 0.0371686 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0367004 |
| HMGB2 | high mobility group box 2 | 0.0366579 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0364347 |
| TPR | translocated promoter region, nuclear basket protein | 0.0360934 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0359565 |
| RBM39 | RNA binding motif protein 39 | 0.0358363 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0355261 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0352886 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0352148 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0351549 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0349381 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0349334 |
| VIM | vimentin | 0.0347303 |
| SCRN1 | secernin 1 | 0.0345638 |
| SET | SET nuclear proto-oncogene | 0.0343315 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0337607 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0333102 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0333084 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0331095 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0327773 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0326123 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0315041 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0314916 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0314766 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.031239 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0312297 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0312051 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.031139 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0309306 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0308998 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0308793 |
| STMN1 | stathmin 1 | 0.0303929 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0300482 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0300195 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0299139 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0298835 |
| TNRC6A | trinucleotide repeat containing 6A | 0.029807 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0295066 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0294936 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0293695 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0293271 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0292556 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.0928239 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.062272 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0596369 |
| ZNF292 | zinc finger protein 292 | -0.0506954 |
| POTEF | POTE ankyrin domain family, member F | -0.0470621 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0418799 |
| DEK | DEK proto-oncogene | -0.0361947 |
| TEX11 | testis expressed 11 | -0.0361276 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0329273 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0300405 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.029627 |
| TMSB10 | thymosin beta 10 | -0.0281922 |
| RHEB | Ras homolog enriched in brain | -0.0275497 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0275166 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0259928 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0245943 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0241623 |
| TAPBP | TAP binding protein (tapasin) | -0.0230141 |
| HMGA1 | high mobility group AT-hook 1 | -0.0224519 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0218461 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0213285 |
| CENPE | centromere protein E, 312kDa | -0.0213253 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0212031 |
| SRPK2 | SRSF protein kinase 2 | -0.0207526 |
| CAPNS1 | calpain, small subunit 1 | -0.0205046 |
| FAM135A | family with sequence similarity 135, member A | -0.0200167 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0192336 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0190883 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0188628 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.0187143 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0187129 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0186478 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0185828 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0185637 |
| BSG | basigin (Ok blood group) | -0.0183104 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0179755 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0176593 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0174681 |
| POU3F2 | POU class 3 homeobox 2 | -0.0174619 |
| ZFP36 | ZFP36 ring finger protein | -0.017434 |
| FTL | ferritin, light polypeptide | -0.0172517 |
| RASAL2 | RAS protein activator like 2 | -0.0172326 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0170631 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0170108 |
| TMEM165 | transmembrane protein 165 | -0.0168527 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0167542 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0167149 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0164734 |
| POGZ | pogo transposable element with ZNF domain | -0.0164564 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0164267 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0163685 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | -0.016296 |
| TOX | thymocyte selection-associated high mobility group box | -0.0161305 |
| RPLP1 | ribosomal protein, large, P1 | -0.0160708 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0158621 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0156531 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.01558 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.0155652 |
| ZNF608 | zinc finger protein 608 | -0.0154871 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0154358 |
| RPF2 | ribosome production factor 2 homolog (S. cerevisiae) | -0.015433 |
| RPL21 | ribosomal protein L21 | -0.0154084 |
| MOB1A | MOB kinase activator 1A | -0.0153794 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0153718 |
| MACROD2 | MACRO domain containing 2 | -0.0153651 |
| NUP188 | nucleoporin 188kDa | -0.0153346 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0152821 |
| VGLL3 | vestigial-like family member 3 | -0.0151948 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0151668 |
| AKIRIN1 | akirin 1 | -0.0151403 |
| EXOC4 | exocyst complex component 4 | -0.014986 |
| TGIF1 | TGFB-induced factor homeobox 1 | -0.0149436 |
| FLVCR1 | feline leukemia virus subgroup C cellular receptor 1 | -0.014915 |
| AHI1 | Abelson helper integration site 1 | -0.0147874 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.01465 |
| RBM20 | RNA binding motif protein 20 | -0.0144625 |
| TRIM2 | tripartite motif containing 2 | -0.0142632 |
| RPL27A | ribosomal protein L27a | -0.014261 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0141638 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0141228 |
| SYNPO2 | synaptopodin 2 | -0.0140572 |
| RPL23A | ribosomal protein L23a | -0.0140224 |
| HELLS | helicase, lymphoid-specific | -0.0140123 |
| TCERG1 | transcription elongation regulator 1 | -0.0140086 |
| LDHB | lactate dehydrogenase B | -0.0138935 |
| TUBA1B | tubulin, alpha 1b | -0.0138444 |
| CHRM3 | cholinergic receptor, muscarinic 3 | -0.0137729 |
| TMEM117 | transmembrane protein 117 | -0.0136517 |
| LAMA2 | laminin, alpha 2 | -0.0134972 |
| INO80 | INO80 complex subunit | -0.0134378 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0133564 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.013296 |
| TSEN15 | TSEN15 tRNA splicing endonuclease subunit | -0.013294 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0132882 |
| PRR11 | proline rich 11 | -0.0132823 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0132639 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0132578 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0131887 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0131414 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 | -0.01309 |
