| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.119028 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0635331 |
| RPL3 | ribosomal protein L3 | 0.0513626 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.049804 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0428239 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0415665 |
| ECT2 | epithelial cell transforming 2 | 0.0352664 |
| APP | amyloid beta (A4) precursor protein | 0.0328575 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0312659 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.030499 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.030265 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.028206 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0278976 |
| CASC3 | cancer susceptibility candidate 3 | 0.0254996 |
| SET | SET nuclear proto-oncogene | 0.0252945 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0248571 |
| NAV2 | neuron navigator 2 | 0.024436 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0231732 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0231477 |
| AEBP2 | AE binding protein 2 | 0.0227281 |
| RPS2 | ribosomal protein S2 | 0.0220136 |
| HMGB2 | high mobility group box 2 | 0.0205689 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0205486 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0205123 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0203197 |
| RAB18 | RAB18, member RAS oncogene family | 0.0195561 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0191105 |
| MSI2 | musashi RNA-binding protein 2 | 0.019042 |
| SFTPA2 | surfactant protein A2 | 0.0190397 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0189013 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0184035 |
| YME1L1 | YME1-like 1 ATPase | 0.0179295 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0178093 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0174592 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0173893 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0173535 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0171711 |
| RBM6 | RNA binding motif protein 6 | 0.0170517 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.016985 |
| STX18 | syntaxin 18 | 0.0169709 |
| RLF | rearranged L-myc fusion | 0.0154548 |
| CENPC | centromere protein C | 0.0153547 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.015145 |
| HDGF | hepatoma-derived growth factor | 0.0145838 |
| TOP1 | topoisomerase (DNA) I | 0.014382 |
| TPX2 | TPX2, microtubule-associated | 0.014345 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | 0.0142987 |
| RPS15A | ribosomal protein S15a | 0.0141138 |
| CRY1 | cryptochrome circadian clock 1 | 0.0141061 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.014057 |
| TERF2 | telomeric repeat binding factor 2 | 0.0140153 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0139141 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0138964 |
| RRM2 | ribonucleotide reductase M2 | 0.0137276 |
| ANKRD36 | ankyrin repeat domain 36 | 0.013707 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0136529 |
| CYTH3 | cytohesin 3 | 0.0135969 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0134912 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0134667 |
| H1-4 | H1.4 linker histone, cluster member | 0.0134295 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.013427 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0133485 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0131972 |
| ANKRD10 | ankyrin repeat domain 10 | 0.013089 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0129257 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0128619 |
| CREBRF | CREB3 regulatory factor | 0.0128055 |
| MATR3 | matrin 3 | 0.0127997 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0124491 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0124427 |
| SPAG5 | sperm associated antigen 5 | 0.0124396 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.01232 |
| FBL | fibrillarin | 0.0123013 |
| OTUD7B | OTU deubiquitinase 7B | 0.012218 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0121996 |
| NONO | non-POU domain containing, octamer-binding | 0.0121943 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0121565 |
| ARGLU1 | arginine and glutamate rich 1 | 0.012116 |
| PCGF5 | polycomb group ring finger 5 | 0.0120536 |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.0119619 |
| ANLN | anillin, actin binding protein | 0.0118319 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.0117913 |
| CENPF | centromere protein F, 350/400kDa | 0.0117676 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0117275 |
| RPL4 | ribosomal protein L4 | 0.0116193 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0115475 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0115418 |
| AHNAK | AHNAK nucleoprotein | 0.0115125 |
| UBAP1 | ubiquitin associated protein 1 | 0.0114892 |
| AMOTL2 | angiomotin like 2 | 0.0114665 |
| SIL1 | SIL1 nucleotide exchange factor | 0.0114404 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0114354 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0114317 |
| PDE7B | phosphodiesterase 7B | 0.0114192 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0113764 |
| COMMD10 | COMM domain containing 10 | 0.0112256 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0112165 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0111882 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.011179 |
| SBDS | Shwachman-Bodian-Diamond syndrome | 0.0111583 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.32064 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.114758 |
| PTMA | prothymosin, alpha | -0.100206 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0978458 |
| EGFR | epidermal growth factor receptor | -0.0967582 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0924509 |
| RPS6 | ribosomal protein S6 | -0.0911888 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.083243 |
| NBEA | neurobeachin | -0.0765595 |
| TJP1 | tight junction protein 1 | -0.0730037 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0686249 |
| EFNA5 | ephrin-A5 | -0.0677352 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.06161 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0612103 |
| POTEF | POTE ankyrin domain family, member F | -0.0605653 |
| ACTG1 | actin gamma 1 | -0.0598232 |
| RBM39 | RNA binding motif protein 39 | -0.0586278 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0580985 |
| RPL35A | ribosomal protein L35a | -0.0564495 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0557248 |
| TXNRD1 | thioredoxin reductase 1 | -0.0544298 |
| LDHA | lactate dehydrogenase A | -0.0538516 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0537853 |
| RPLP1 | ribosomal protein, large, P1 | -0.0522001 |
| S100A6 | S100 calcium binding protein A6 | -0.0518675 |
| FOXP1 | forkhead box P1 | -0.0516355 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0502024 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0500521 |
| RPL12 | ribosomal protein L12 | -0.0496497 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0485355 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0481985 |
| PKM | pyruvate kinase, muscle | -0.047784 |
| RPLP2 | ribosomal protein, large, P2 | -0.0473524 |
| RPS19 | ribosomal protein S19 | -0.0465663 |
| RHOA | ras homolog family member A | -0.0465128 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0461296 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0453013 |
| RPL34 | ribosomal protein L34 | -0.0449589 |
| RPS23 | ribosomal protein S23 | -0.0440232 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0439287 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0438201 |
| SMYD3 | SET and MYND domain containing 3 | -0.0437201 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0436082 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.042874 |
| RPL31 | ribosomal protein L31 | -0.0425137 |
| RPL26 | ribosomal protein L26 | -0.0422787 |
| RPL9 | ribosomal protein L9 | -0.0417898 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0410374 |
| RPS24 | ribosomal protein S24 | -0.0403349 |
| RPS8 | ribosomal protein S8 | -0.0396169 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0393982 |
| RPS13 | ribosomal protein S13 | -0.0390061 |
| RPL11 | ribosomal protein L11 | -0.0379806 |
| NF1 | neurofibromin 1 | -0.0378448 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0369897 |
| PYGB | phosphorylase, glycogen; brain | -0.0367049 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0363403 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0359749 |
| RTN4 | reticulon 4 | -0.0356201 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.035516 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0354955 |
| RPS12 | ribosomal protein S12 | -0.035115 |
| RPL27A | ribosomal protein L27a | -0.0350648 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0349695 |
| RPLP0 | ribosomal protein, large, P0 | -0.0347672 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0344385 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0342622 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0336624 |
| RBM25 | RNA binding motif protein 25 | -0.0335454 |
| EXOC6B | exocyst complex component 6B | -0.0328674 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0321383 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0317325 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0316545 |
| RPL19 | ribosomal protein L19 | -0.0313958 |
| PTEN | phosphatase and tensin homolog | -0.0312311 |
| RPL36A | ribosomal protein L36a | -0.0311573 |
| HMGA1 | high mobility group AT-hook 1 | -0.030873 |
| GLI2 | GLI family zinc finger 2 | -0.0303499 |
| FHIT | fragile histidine triad | -0.0302084 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0300408 |
| RPS27 | ribosomal protein S27 | -0.0298095 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0296727 |
| PFN1 | profilin 1 | -0.0296252 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0294732 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0291227 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0288886 |
| RPS25 | ribosomal protein S25 | -0.0285643 |
| RPS11 | ribosomal protein S11 | -0.0284803 |
| ZNF292 | zinc finger protein 292 | -0.0283309 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0283247 |
| FLNB | filamin B, beta | -0.0282331 |
| NBAS | neuroblastoma amplified sequence | -0.0281159 |
| PCM1 | pericentriolar material 1 | -0.0281003 |
| SETD5 | SET domain containing 5 | -0.0280774 |
| TMEM65 | transmembrane protein 65 | -0.0280659 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.0275182 |
| RPL13A | ribosomal protein L13a | -0.0275034 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0274173 |
| RPL37A | ribosomal protein L37a | -0.0272745 |
| TMSB10 | thymosin beta 10 | -0.0272571 |
