| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.374129 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.16239 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.111385 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0950582 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0793259 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.077352 |
| SFTPA2 | surfactant protein A2 | 0.0757557 |
| STC1 | stanniocalcin 1 | 0.0749601 |
| AHNAK | AHNAK nucleoprotein | 0.074918 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0743805 |
| ADM | adrenomedullin | 0.0700998 |
| MSN | moesin | 0.0621574 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0612126 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0598691 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0585529 |
| OGA | O-GlcNAcase | 0.0582429 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0568749 |
| TMSB4X | thymosin beta 4, X-linked | 0.0560971 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0553717 |
| NAV2 | neuron navigator 2 | 0.0551692 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0536649 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0531127 |
| CEP250 | centrosomal protein 250kDa | 0.0530354 |
| SDC4 | syndecan 4 | 0.0513474 |
| DST | dystonin | 0.050905 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0498682 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0491918 |
| PRELID2 | PRELI domain containing 2 | 0.0489206 |
| VIM | vimentin | 0.0481247 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.046671 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0459552 |
| ANLN | anillin, actin binding protein | 0.0452239 |
| CENPF | centromere protein F, 350/400kDa | 0.0448223 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0445231 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0442498 |
| CUL4B | cullin 4B | 0.0441916 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0437829 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0432997 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0420429 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0418817 |
| ARRDC3 | arrestin domain containing 3 | 0.0418157 |
| DIAPH3 | diaphanous-related formin 3 | 0.0417859 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0413248 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0412605 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0411175 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0408319 |
| PGK1 | phosphoglycerate kinase 1 | 0.039915 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0398423 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0394192 |
| APP | amyloid beta (A4) precursor protein | 0.0391003 |
| FBXO32 | F-box protein 32 | 0.0376854 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0373634 |
| JMJD1C | jumonji domain containing 1C | 0.0366996 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0364466 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0360663 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0351565 |
| OPTN | optineurin | 0.0351497 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0349664 |
| KIF4A | kinesin family member 4A | 0.0346485 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0345369 |
| DUSP5 | dual specificity phosphatase 5 | 0.0342117 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0341686 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.03397 |
| SQSTM1 | sequestosome 1 | 0.0339558 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0339193 |
| CALR | calreticulin | 0.033379 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.033033 |
| SERINC1 | serine incorporator 1 | 0.032898 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0325749 |
| PTMA | prothymosin, alpha | 0.0323922 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0319503 |
| RPL7A | ribosomal protein L7a | 0.0317009 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.03151 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0312256 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0310738 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0306156 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0304498 |
| IGF2R | insulin-like growth factor 2 receptor | 0.030346 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0300177 |
| TPM3 | tropomyosin 3 | 0.0298603 |
| HDAC9 | histone deacetylase 9 | 0.0296627 |
| MKI67 | marker of proliferation Ki-67 | 0.0295167 |
| EZR | ezrin | 0.0291051 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0289047 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.0278782 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0277663 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0275075 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0274117 |
| DSPP | dentin sialophosphoprotein | 0.0274038 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0272347 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0271228 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0271037 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0269403 |
| MCL1 | myeloid cell leukemia 1 | 0.0268237 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0265003 |
| IER2 | immediate early response 2 | 0.0264795 |
| CPNE1 | copine I | 0.0264128 |
| RNF213 | ring finger protein 213 | 0.0263676 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0261558 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0261303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.129375 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.126411 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10319 |
| BICC1 | BicC family RNA binding protein 1 | -0.081533 |
| CADM1 | cell adhesion molecule 1 | -0.0715169 |
| VCL | vinculin | -0.0553137 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0544415 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.053784 |
| FTL | ferritin, light polypeptide | -0.0526867 |
| QKI | QKI, KH domain containing, RNA binding | -0.0522592 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0484243 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0483784 |
| CTSD | cathepsin D | -0.0467416 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0439995 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0426913 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0425586 |
| RPS6 | ribosomal protein S6 | -0.0422356 |
| TAPBP | TAP binding protein (tapasin) | -0.0404211 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0390348 |
| NAV1 | neuron navigator 1 | -0.0370558 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0368582 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0359318 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0356988 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0354336 |
| HMGA1 | high mobility group AT-hook 1 | -0.0352901 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0348525 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0344747 |
| RPLP1 | ribosomal protein, large, P1 | -0.0344577 |
| PALLD | palladin, cytoskeletal associated protein | -0.0333686 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0324611 |
| TMEM123 | transmembrane protein 123 | -0.031888 |
| HLA-A | major histocompatibility complex, class I, A | -0.0303087 |
| ERBIN | erbb2 interacting protein | -0.029707 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0293607 |
| SMAD2 | SMAD family member 2 | -0.0293182 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0287802 |
| POTEF | POTE ankyrin domain family, member F | -0.0285336 |
| PRR16 | proline rich 16 | -0.0281548 |
| LOX | lysyl oxidase | -0.0278271 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0278093 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0277665 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0275099 |
| RPL35A | ribosomal protein L35a | -0.0272928 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.027019 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0268606 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0265362 |
| HLA-B | major histocompatibility complex, class I, B | -0.0263966 |
| RPL9 | ribosomal protein L9 | -0.025446 |
| FNDC3B | fibronectin type III domain containing 3B | -0.025341 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0252992 |
| EGR1 | early growth response 1 | -0.024722 |
| TFG | TRK-fused gene | -0.0246844 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0244407 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0244181 |
| ANXA2 | annexin A2 | -0.024104 |
| NABP1 | nucleic acid binding protein 1 | -0.0240202 |
| GPC6 | glypican 6 | -0.0239038 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0238604 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0237568 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0236109 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.02356 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0234402 |
| TMEM178B | transmembrane protein 178B | -0.0230221 |
| RPS8 | ribosomal protein S8 | -0.0228936 |
| RPL39 | ribosomal protein L39 | -0.0228573 |
| TMSB10 | thymosin beta 10 | -0.0219938 |
| MEF2A | myocyte enhancer factor 2A | -0.0213203 |
| MAP1B | microtubule-associated protein 1B | -0.0211673 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0211384 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0211118 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0210594 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0210389 |
| B2M | beta-2-microglobulin | -0.0210011 |
| RPL30 | ribosomal protein L30 | -0.0209636 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0209096 |
| JAK2 | Janus kinase 2 | -0.02062 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0204109 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.01997 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0199107 |
| RAI14 | retinoic acid induced 14 | -0.0196951 |
| CCNL1 | cyclin L1 | -0.0196679 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0196293 |
| PDE10A | phosphodiesterase 10A | -0.0193035 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0192653 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0192107 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0190963 |
| SEC24D | SEC24 family member D | -0.0190856 |
| VMP1 | vacuole membrane protein 1 | -0.0190211 |
| CRY1 | cryptochrome circadian clock 1 | -0.0190201 |
| NTN4 | netrin 4 | -0.0188075 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0187404 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0186975 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0186763 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0186754 |
| PFN1 | profilin 1 | -0.0183413 |
| TOP1 | topoisomerase (DNA) I | -0.0183016 |
| PLSCR1 | phospholipid scramblase 1 | -0.0182969 |
| TPM1 | tropomyosin 1 (alpha) | -0.0181974 |
| RPS24 | ribosomal protein S24 | -0.0181973 |
| HELZ | helicase with zinc finger | -0.0179695 |
