| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Uridine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.253347 |
| COL6A3 | collagen, type VI, alpha 3 | 0.196304 |
| PRSS23 | protease, serine, 23 | 0.13169 |
| B2M | beta-2-microglobulin | 0.126407 |
| ADM | adrenomedullin | 0.0983643 |
| STC1 | stanniocalcin 1 | 0.0923659 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0792906 |
| CDH13 | cadherin 13 | 0.075119 |
| FMNL2 | formin-like 2 | 0.069379 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0634612 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0621386 |
| COL5A1 | collagen, type V, alpha 1 | 0.0600682 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0574441 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0572687 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0570497 |
| PLEC | plectin | 0.0559781 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0535356 |
| RBM25 | RNA binding motif protein 25 | 0.0526218 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.052032 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0519329 |
| ANO6 | anoctamin 6 | 0.0512483 |
| ARRDC3 | arrestin domain containing 3 | 0.0509278 |
| CAVIN1 | caveolae associated protein 1 | 0.0506108 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0504248 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.050054 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0487341 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0482916 |
| RAI14 | retinoic acid induced 14 | 0.0481754 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0474072 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.047033 |
| FRMD6 | FERM domain containing 6 | 0.0466115 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0451357 |
| MYO10 | myosin X | 0.0437132 |
| JUN | jun proto-oncogene | 0.0436419 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0436133 |
| CALU | calumenin | 0.0429396 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0421702 |
| ATP13A3 | ATPase type 13A3 | 0.0417402 |
| PGK1 | phosphoglycerate kinase 1 | 0.0414493 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0404958 |
| CALD1 | caldesmon 1 | 0.0400315 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0398107 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0397126 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0396755 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0395388 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0394898 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0391441 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0385146 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.037981 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0378526 |
| CALR | calreticulin | 0.037603 |
| LOXL2 | lysyl oxidase-like 2 | 0.037475 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0374141 |
| TFG | TRK-fused gene | 0.0373212 |
| IL6 | interleukin 6 | 0.0368597 |
| AK1 | adenylate kinase 1 | 0.0367157 |
| SDC4 | syndecan 4 | 0.0364584 |
| COL5A2 | collagen, type V, alpha 2 | 0.0361415 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0361333 |
| MSN | moesin | 0.0357171 |
| GLIS3 | GLIS family zinc finger 3 | 0.0356197 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0352488 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0349209 |
| PRELID2 | PRELI domain containing 2 | 0.0346973 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0344879 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0344397 |
| IL6ST | interleukin 6 signal transducer | 0.0341709 |
| TUBB | tubulin, beta class I | 0.0338661 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0338461 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0336207 |
| AHNAK | AHNAK nucleoprotein | 0.0332073 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0326656 |
| TPM4 | tropomyosin 4 | 0.0326482 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0323726 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0319821 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.031898 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.03187 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0316536 |
| RPL3 | ribosomal protein L3 | 0.0316489 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | 0.0314111 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0309166 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0308987 |
| SMAD3 | SMAD family member 3 | 0.0306898 |
| TMSB4X | thymosin beta 4, X-linked | 0.0306763 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0305995 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0303496 |
| APP | amyloid beta (A4) precursor protein | 0.0303038 |
| VEGFA | vascular endothelial growth factor A | 0.0298235 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0296571 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0296253 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0296092 |
| ANXA1 | annexin A1 | 0.0292859 |
| ACTN4 | actinin, alpha 4 | 0.0292269 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0291822 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.029071 |
| TPM2 | tropomyosin 2 (beta) | 0.0289789 |
| HDLBP | high density lipoprotein binding protein | 0.028938 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0289239 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0287226 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0286856 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.292036 |
| NDRG1 | N-myc downstream regulated 1 | -0.133307 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0810063 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.067881 |
| POTEF | POTE ankyrin domain family, member F | -0.0604192 |
| VIM | vimentin | -0.0581973 |
| RTN4 | reticulon 4 | -0.056575 |
| JMJD1C | jumonji domain containing 1C | -0.0506362 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0495511 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0469301 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0436435 |
| MEF2A | myocyte enhancer factor 2A | -0.043528 |
| FN1 | fibronectin 1 | -0.0434815 |
| ASPH | aspartate beta-hydroxylase | -0.0414189 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0405154 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0402202 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0377493 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0361583 |
| RLF | rearranged L-myc fusion | -0.0358643 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0348395 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0346644 |
| RPL28 | ribosomal protein L28 | -0.0342292 |
| HDAC9 | histone deacetylase 9 | -0.033699 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0329006 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0328246 |
| HIP1 | huntingtin interacting protein 1 | -0.0327 |
| RBM33 | RNA binding motif protein 33 | -0.0325189 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0322772 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0318128 |
| PKM | pyruvate kinase, muscle | -0.0316123 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0301846 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0300191 |
| FTL | ferritin, light polypeptide | -0.0299907 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0297232 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0289985 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0284954 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0281752 |
| MATR3 | matrin 3 | -0.0280645 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0280112 |
| CENPF | centromere protein F, 350/400kDa | -0.0279597 |
| ACER3 | alkaline ceramidase 3 | -0.0279293 |
| INSIG1 | insulin induced gene 1 | -0.027738 |
| EGFR | epidermal growth factor receptor | -0.0276652 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.0273322 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0272261 |
| CUL3 | cullin 3 | -0.0271495 |
| HELZ | helicase with zinc finger | -0.0269717 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0262979 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0260711 |
| NAV2 | neuron navigator 2 | -0.0259992 |
| RAB31 | RAB31, member RAS oncogene family | -0.0259438 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0259313 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.0258789 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0257395 |
| USP34 | ubiquitin specific peptidase 34 | -0.025679 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0250685 |
| RPLP1 | ribosomal protein, large, P1 | -0.0250658 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0249744 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0249309 |
| WASHC4 | WASH complex subunit 4 | -0.0246802 |
| SEPTIN2 | septin 2 | -0.0245537 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0245462 |
| UBAP2 | ubiquitin associated protein 2 | -0.0244018 |
| ITM2B | integral membrane protein 2B | -0.024227 |
| CDC27 | cell division cycle 27 | -0.0241986 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.024173 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0241118 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0240629 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0238819 |
| ATF6 | activating transcription factor 6 | -0.0238532 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0238095 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0237862 |
| CDK19 | cyclin-dependent kinase 19 | -0.0237426 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0237056 |
| SLC25A51 | solute carrier family 25, member 51 | -0.023478 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0233749 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0233381 |
| RPL11 | ribosomal protein L11 | -0.0232613 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0231603 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0231073 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0230567 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0228722 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0228329 |
| IRF1 | interferon regulatory factor 1 | -0.022765 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0226903 |
| SEPTIN7 | septin 7 | -0.0225972 |
| NEMF | nuclear export mediator factor | -0.0225543 |
| RAP1A | RAP1A, member of RAS oncogene family | -0.0224923 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0224597 |
| FMR1 | fragile X mental retardation 1 | -0.0223401 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.022299 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0222073 |
| RAI1 | retinoic acid induced 1 | -0.0221095 |
| LMO7 | LIM domain 7 | -0.022095 |
| MAGT1 | magnesium transporter 1 | -0.022056 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0220028 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0219848 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0218635 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.021662 |
| XPO1 | exportin 1 | -0.0216471 |