| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Uridine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.139463 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0928031 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0834735 |
| CANX | calnexin | 0.0834698 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0823613 |
| AHNAK | AHNAK nucleoprotein | 0.0735938 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0710476 |
| DSCAM | Down syndrome cell adhesion molecule | 0.069972 |
| DST | dystonin | 0.0695589 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0684614 |
| PKM | pyruvate kinase, muscle | 0.0658229 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0649756 |
| CEP250 | centrosomal protein 250kDa | 0.0604668 |
| LDHA | lactate dehydrogenase A | 0.0600362 |
| CUL4B | cullin 4B | 0.059946 |
| MSN | moesin | 0.0597466 |
| NUP58 | nucleoporin 58 | 0.0586193 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0584549 |
| RBM39 | RNA binding motif protein 39 | 0.0555142 |
| CAPRIN2 | caprin family member 2 | 0.0544184 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0542518 |
| PTMA | prothymosin, alpha | 0.0542123 |
| VIM | vimentin | 0.0532518 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0530512 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0506149 |
| GOLGA4 | golgin A4 | 0.0498357 |
| NKTR | natural killer cell triggering receptor | 0.0490249 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0486897 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0485323 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.048322 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0478677 |
| ANXA1 | annexin A1 | 0.0478132 |
| PGK1 | phosphoglycerate kinase 1 | 0.0476542 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0474958 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0473389 |
| YBX3 | Y box binding protein 3 | 0.0471626 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0467385 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.046614 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0459444 |
| PHF3 | PHD finger protein 3 | 0.0448128 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0444059 |
| CPNE1 | copine I | 0.0443954 |
| HMGB2 | high mobility group box 2 | 0.0440912 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0440148 |
| PHF20 | PHD finger protein 20 | 0.0439558 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0430951 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0426206 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0423112 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0416053 |
| ATP13A3 | ATPase type 13A3 | 0.04144 |
| B2M | beta-2-microglobulin | 0.0412935 |
| OGA | O-GlcNAcase | 0.0403553 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0403416 |
| PYGL | phosphorylase, glycogen, liver | 0.0402009 |
| CALR | calreticulin | 0.0401952 |
| ANLN | anillin, actin binding protein | 0.0400417 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0393773 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0390807 |
| LOC112694756 | uncharaterized LOC112694756 | 0.038725 |
| XPO1 | exportin 1 | 0.0387131 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0384944 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0383917 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0382303 |
| NONO | non-POU domain containing, octamer-binding | 0.0376639 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.037302 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0371211 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0370069 |
| YAP1 | Yes-associated protein 1 | 0.0366515 |
| ITSN2 | intersectin 2 | 0.0366395 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0359805 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0355366 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0354516 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0354442 |
| ARRDC3 | arrestin domain containing 3 | 0.0354228 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0352058 |
| ANKRD36 | ankyrin repeat domain 36 | 0.035131 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0350668 |
| FMNL2 | formin-like 2 | 0.0349049 |
| SMYD3 | SET and MYND domain containing 3 | 0.0348135 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0347416 |
| SET | SET nuclear proto-oncogene | 0.0347142 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0344164 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.032839 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0322935 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0319168 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0317812 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0317029 |
| RPL3 | ribosomal protein L3 | 0.0316149 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.03138 |
| NDRG1 | N-myc downstream regulated 1 | 0.0313368 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0313201 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0312126 |
| CEP295 | centrosomal protein 295kDa | 0.0308449 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0307994 |
| ENO1 | enolase 1, (alpha) | 0.0306518 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0303989 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0303902 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0302575 |
| ATXN1 | ataxin 1 | 0.0301731 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0300253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0681368 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0479192 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0451496 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.044963 |
| NLK | nemo-like kinase | -0.0395267 |
| RIN2 | Ras and Rab interactor 2 | -0.0349958 |
| OSMR | oncostatin M receptor | -0.0336949 |
| MORF4L1 | mortality factor 4 like 1 | -0.033587 |
| NALCN | sodium leak channel, non selective | -0.0329643 |
| CCDC14 | coiled-coil domain containing 14 | -0.0326777 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0316287 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0314667 |
| BSG | basigin (Ok blood group) | -0.0309184 |
| CCDC91 | coiled-coil domain containing 91 | -0.0298441 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0297451 |
| TAOK3 | TAO kinase 3 | -0.0294862 |
| POTEF | POTE ankyrin domain family, member F | -0.0291462 |
| NAV2 | neuron navigator 2 | -0.0289633 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0283495 |
| EFL1 | elongation factor like GTPase 1 | -0.0281866 |
| HJURP | Holliday junction recognition protein | -0.0276699 |
| BPTF | bromodomain PHD finger transcription factor | -0.0272715 |
| RIGI | RNA sensor RIG-I | -0.02711 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0269916 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0266154 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0265782 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0265061 |
| PCNX4 | pecanex 4 | -0.0263305 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0261654 |
| RPS25 | ribosomal protein S25 | -0.0260492 |
| LAMA5 | laminin, alpha 5 | -0.0257282 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0252834 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0249541 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0249318 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.0248829 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0242121 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0240542 |
| ATF6 | activating transcription factor 6 | -0.0238612 |
| HBS1L | HBS1-like translational GTPase | -0.023601 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0235555 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0228298 |
| DNER | delta/notch-like EGF repeat containing | -0.0228172 |
| SMAD3 | SMAD family member 3 | -0.0226589 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0222318 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.022228 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0222118 |
| CAPN7 | calpain 7 | -0.0221813 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0218779 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0217745 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0216166 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.021512 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0214984 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0213239 |
| ATXN3 | ataxin 3 | -0.0212458 |
| SPAG9 | sperm associated antigen 9 | -0.0212055 |
| SCFD1 | sec1 family domain containing 1 | -0.0211041 |
| SVIL | supervillin | -0.0210987 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0210435 |
| PDE8A | phosphodiesterase 8A | -0.0210087 |
| KIAA1328 | KIAA1328 | -0.0208784 |
| ETV6 | ets variant 6 | -0.0208762 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | -0.0207988 |
| MTMR3 | myotubularin related protein 3 | -0.0207966 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0207781 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0207298 |
| SMAD2 | SMAD family member 2 | -0.0205683 |
| RPLP1 | ribosomal protein, large, P1 | -0.0205656 |
| SIK2 | salt-inducible kinase 2 | -0.0205591 |
| SAP30BP | SAP30 binding protein | -0.0205509 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.020216 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | -0.0201986 |
| TMSB10 | thymosin beta 10 | -0.0201355 |
| IL31RA | interleukin 31 receptor A | -0.020036 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0200146 |
| ZNF609 | zinc finger protein 609 | -0.0200033 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.019936 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0198663 |
| HMGA1 | high mobility group AT-hook 1 | -0.0197567 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0196981 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0196341 |
| MECP2 | methyl CpG binding protein 2 | -0.0195398 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0195024 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0193874 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0192058 |
| MCC | mutated in colorectal cancers | -0.0190122 |
| NHLRC2 | NHL repeat containing 2 | -0.0189948 |
| EFCAB14 | EF-hand calcium binding domain 14 | -0.0189033 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0187968 |
| RBM27 | RNA binding motif protein 27 | -0.0187302 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0187087 |
| PEX14 | peroxisomal biogenesis factor 14 | -0.0186727 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0186501 |
| STAT5B | signal transducer and activator of transcription 5B | -0.0186253 |
| CKAP2 | cytoskeleton associated protein 2 | -0.018443 |
| RREB1 | ras responsive element binding protein 1 | -0.0184232 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0184127 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.018406 |
| ADIPOR2 | adiponectin receptor 2 | -0.0183236 |
| STXBP1 | syntaxin binding protein 1 | -0.0183208 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0182557 |