| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.144632 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.124881 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.116928 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0954755 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0948455 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0947114 |
| TMSB4X | thymosin beta 4, X-linked | 0.0855578 |
| TXNIP | thioredoxin interacting protein | 0.0788609 |
| CANX | calnexin | 0.0727187 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0712874 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0698843 |
| SFTPA2 | surfactant protein A2 | 0.0677081 |
| AHR | aryl hydrocarbon receptor | 0.0641831 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0632732 |
| TPR | translocated promoter region, nuclear basket protein | 0.0624412 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0617458 |
| SQSTM1 | sequestosome 1 | 0.0597838 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0591687 |
| TPI1 | triosephosphate isomerase 1 | 0.0579249 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0522141 |
| PTMA | prothymosin, alpha | 0.0517884 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0515043 |
| B2M | beta-2-microglobulin | 0.0502058 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0485133 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0482373 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0472504 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0455261 |
| YME1L1 | YME1-like 1 ATPase | 0.0454133 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0446711 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0412483 |
| DST | dystonin | 0.0407593 |
| APP | amyloid beta (A4) precursor protein | 0.0404746 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0402382 |
| AFDN | afadin, adherens junction formation factor | 0.0399296 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0397262 |
| CLTC | clathrin, heavy chain (Hc) | 0.0393646 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.039284 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0386122 |
| CALR | calreticulin | 0.0386042 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0371269 |
| TPM3 | tropomyosin 3 | 0.0369812 |
| LMNA | lamin A/C | 0.036368 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0353893 |
| ENO1 | enolase 1, (alpha) | 0.0353613 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0353143 |
| MKI67 | marker of proliferation Ki-67 | 0.0352551 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0351208 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0343014 |
| PGK1 | phosphoglycerate kinase 1 | 0.0334951 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0334075 |
| RBM39 | RNA binding motif protein 39 | 0.0333493 |
| RRBP1 | ribosome binding protein 1 | 0.033253 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0329419 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0328468 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.032804 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0327647 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0323743 |
| VIM | vimentin | 0.0319844 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0318617 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0317878 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0315778 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.031062 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0307344 |
| CALU | calumenin | 0.030635 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0302999 |
| RAD21 | RAD21 homolog (S. pombe) | 0.030178 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0294994 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0294778 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0292461 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0291968 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0291363 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.02906 |
| OGA | O-GlcNAcase | 0.0290137 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0287465 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0284685 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.028459 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0279066 |
| AHNAK | AHNAK nucleoprotein | 0.0278853 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0278674 |
| RBM25 | RNA binding motif protein 25 | 0.0278098 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0276734 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0274283 |
| RANBP2 | RAN binding protein 2 | 0.0272762 |
| PRPF8 | pre-mRNA processing factor 8 | 0.027209 |
| TMF1 | TATA element modulatory factor 1 | 0.0269803 |
| FAT1 | FAT atypical cadherin 1 | 0.0269552 |
| GOLGA3 | golgin A3 | 0.0268349 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0268326 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0267767 |
| PKM | pyruvate kinase, muscle | 0.0266688 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0263755 |
| XPO1 | exportin 1 | 0.026277 |
| SEPTIN9 | septin 9 | 0.02612 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0259993 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0256 |
| RPS3 | ribosomal protein S3 | 0.0255424 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0255163 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0254892 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0251635 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0250681 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.186359 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14589 |
| HMGA2 | high mobility group AT-hook 2 | -0.13384 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.121692 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0773888 |
| TMEM165 | transmembrane protein 165 | -0.0556001 |
| SYT1 | synaptotagmin I | -0.0554589 |
| NRP1 | neuropilin 1 | -0.0553074 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0510217 |
| NTN4 | netrin 4 | -0.0495849 |
| FN1 | fibronectin 1 | -0.0422119 |
| ITGA1 | integrin, alpha 1 | -0.0352371 |
| NDRG1 | N-myc downstream regulated 1 | -0.0349786 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0329302 |
| VMP1 | vacuole membrane protein 1 | -0.0323477 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0320672 |
| GLIS3 | GLIS family zinc finger 3 | -0.0316854 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0302243 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0299032 |
| HMGA1 | high mobility group AT-hook 1 | -0.0276014 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0273701 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0272821 |
| MAP1B | microtubule-associated protein 1B | -0.0267896 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0252702 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0246795 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0244178 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0241689 |
| EGR1 | early growth response 1 | -0.0241517 |
| POTEF | POTE ankyrin domain family, member F | -0.0240295 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0238588 |
| VCL | vinculin | -0.0232351 |
| PTK2 | protein tyrosine kinase 2 | -0.0231622 |
| EFNA5 | ephrin-A5 | -0.0225795 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0213373 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0210135 |
| TFG | TRK-fused gene | -0.0201638 |
| PALLD | palladin, cytoskeletal associated protein | -0.0201296 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0199219 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.01991 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0196971 |
| ATN1 | atrophin 1 | -0.0196699 |
| AGRN | agrin | -0.0196585 |
| RPL9 | ribosomal protein L9 | -0.0196489 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0195935 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0192489 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0191461 |
| GLCCI1 | glucocorticoid induced 1 | -0.01901 |
| ETNK1 | ethanolamine kinase 1 | -0.0187294 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0186257 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0184161 |
| HPCAL1 | hippocalcin-like 1 | -0.0182478 |
| ADIPOR2 | adiponectin receptor 2 | -0.0181859 |
| EMP1 | epithelial membrane protein 1 | -0.0180893 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0180681 |
| KSR1 | kinase suppressor of ras 1 | -0.0179536 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0177935 |
| RUNX2 | runt-related transcription factor 2 | -0.0175821 |
| IFI44L | interferon-induced protein 44-like | -0.0174498 |
| SEC24D | SEC24 family member D | -0.0172483 |
| MEF2D | myocyte enhancer factor 2D | -0.0172182 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0171444 |
| VEGFA | vascular endothelial growth factor A | -0.0171413 |
| FHL2 | four and a half LIM domains 2 | -0.0170379 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | -0.0169286 |
| VCAN | versican | -0.0168409 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0167977 |
| UBTD2 | ubiquitin domain containing 2 | -0.0166806 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0166793 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0166658 |
| NXN | nucleoredoxin | -0.0164492 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0162605 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.016207 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0161768 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0159658 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0158322 |
| RPL35A | ribosomal protein L35a | -0.0156182 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0154439 |
| RNF145 | ring finger protein 145 | -0.0154045 |
| DHFR | dihydrofolate reductase | -0.0153805 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0152929 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0149195 |
| RIGI | RNA sensor RIG-I | -0.0148132 |
| TGFA | transforming growth factor, alpha | -0.0147381 |
| FERMT2 | fermitin family member 2 | -0.0146633 |
| MX2 | MX dynamin-like GTPase 2 | -0.014565 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0145625 |
| TUFT1 | tuftelin 1 | -0.0144513 |
| UBAP1 | ubiquitin associated protein 1 | -0.0141532 |
| RPS20 | ribosomal protein S20 | -0.0141189 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.01409 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0140898 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0140507 |
| TRIB1 | tribbles pseudokinase 1 | -0.0139192 |
| FOSL1 | FOS-like antigen 1 | -0.0137648 |
| TNNC1 | troponin C type 1 (slow) | -0.0136895 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0136866 |
| RPL30 | ribosomal protein L30 | -0.0135039 |
| LMAN2 | lectin, mannose-binding 2 | -0.0134334 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0134329 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0134153 |
