Urinary Incontinence Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Loss of the ability to control the urinary bladder leading to involuntary urination. (Human Phenotype Ontology, HP_0000020)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D014549
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Genes

107 genes/proteins associated with the disease Urinary Incontinence from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.20735
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.13338
CAT catalase 1.99746
PRL prolactin 1.92833
TNF tumor necrosis factor 1.91781
FOS FBJ murine osteosarcoma viral oncogene homolog 1.89698
BCL2 B-cell CLL/lymphoma 2 1.8854
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.83699
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.79637
MAPK1 mitogen-activated protein kinase 1 1.7716
BAX BCL2-associated X protein 1.75361
BDNF brain-derived neurotrophic factor 1.75142
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.72821
MAPK3 mitogen-activated protein kinase 3 1.71748
TAC1 tachykinin, precursor 1 1.71482
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.70035
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.59381
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.56875
INS insulin 1.56875
EGR1 early growth response 1 1.56828
IL10 interleukin 10 1.54669
VEGFA vascular endothelial growth factor A 1.53699
IL1B interleukin 1, beta 1.53184
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.51911
REN renin 1.50323
IFNG interferon, gamma 1.49252
IL6 interleukin 6 1.49174
NOS2 nitric oxide synthase 2, inducible 1.45962
AVP arginine vasopressin 1.39813
TP53 tumor protein p53 1.39338
DRD2 dopamine receptor D2 1.3931
HMOX1 heme oxygenase 1 1.39226
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.36848
IL2 interleukin 2 1.36735
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.36677
CXCL8 chemokine (C-X-C motif) ligand 8 1.36677
GSTP1 glutathione S-transferase pi 1 1.36304
ADRB1 adrenoceptor beta 1 1.36275
CRH corticotropin releasing hormone 1.34897
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.34782
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.34635
NPY neuropeptide Y 1.33583
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.32876
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.31656
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.31119
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.31089
TGFB1 transforming growth factor, beta 1 1.30177
VCAM1 vascular cell adhesion molecule 1 1.30087
TAGLN transgelin 1.28027
FAS Fas cell surface death receptor 1.26947
JUN jun proto-oncogene 1.26638
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.24623
DDIT3 DNA-damage-inducible transcript 3 1.24024
RGS4 regulator of G-protein signaling 4 1.23899
NPPB natriuretic peptide B 1.22632
FABP1 fatty acid binding protein 1, liver 1.22632
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.21759
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.21631
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.21567
ACHE acetylcholinesterase (Yt blood group) 1.21501
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.20816
EDNRB endothelin receptor type B 1.20751
DRD1 dopamine receptor D1 1.20394
DUSP1 dual specificity phosphatase 1 1.20295
GAP43 growth associated protein 43 1.19412
CCL2 chemokine (C-C motif) ligand 2 1.18751
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.18554
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.169
SOD1 superoxide dismutase 1, soluble 1.16733
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.16269
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.15967
HRH1 histamine receptor H1 1.15967
IL1A interleukin 1, alpha 1.15526
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.15391
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.14885
F2 coagulation factor II (thrombin) 1.1485
CREB1 cAMP responsive element binding protein 1 1.13655
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.13449
COMT catechol-O-methyltransferase 1.13347
POMC proopiomelanocortin 1.13109
EGR2 early growth response 2 1.12872
GSK3B glycogen synthase kinase 3 beta 1.11809
PF4 platelet factor 4 1.11741
IL4 interleukin 4 1.1122
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.11011
EGR3 early growth response 3 1.10803
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.10562
PRKCB protein kinase C, beta 1.10424
MAPK8 mitogen-activated protein kinase 8 1.09506
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.08513
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.08301
CCND3 cyclin D3 1.07768
MAP2 microtubule-associated protein 2 1.07518
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.07199
TGFB2 transforming growth factor, beta 2 1.06881
LHB luteinizing hormone beta polypeptide 1.06044
GSTM1 glutathione S-transferase mu 1 1.06044
BCL2L1 BCL2-like 1 1.06008
NUPR1 nuclear protein, transcriptional regulator, 1 1.05828
INHBE inhibin, beta E 1.05386
SOD2 superoxide dismutase 2, mitochondrial 1.05274
MAPK14 mitogen-activated protein kinase 14 1.02821
MPO myeloperoxidase 1.02262
IGF1 insulin-like growth factor 1 (somatomedin C) 1.02077
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.0204
ADORA2A adenosine A2a receptor 1.0189
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 1.01361