Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/503076a2-6196-11e5-8ac5-06603eb7f303
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Genes

42 proteins participating in the Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling pathway from the PID Pathways dataset.

Symbol Name
BCAR1 breast cancer anti-estrogen resistance 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTRC chymotrypsin C (caldecrin)
CTSG cathepsin G
DOCK1 dedicator of cytokinesis 1
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FN1 fibronectin 1
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FPR3 formyl peptide receptor 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
KLK4 kallikrein-related peptidase 4
LRP1 low density lipoprotein receptor-related protein 1
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
NCL nucleolin
PDGFD platelet derived growth factor D
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TGFB1 transforming growth factor, beta 1
VLDLR very low density lipoprotein receptor
VTN vitronectin