Urolithiasis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description presence of calculi in any part of the urinary system (Mammalian Phenotype Ontology, MP_0005360)
External Link https://www.disgenet.org/browser/0/1/0/C0451641
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Genes

65 genes associated with the disease Urolithiasis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGXT alanine-glyoxylate aminotransferase
AHSG alpha-2-HS-glycoprotein
ALB albumin
ALPP alkaline phosphatase, placental
APRT adenine phosphoribosyltransferase
AR androgen receptor
ARL5B ADP-ribosylation factor-like 5B
ASRGL1 asparaginase like 1
ATRNL1 attractin-like 1
BCAS3 breast carcinoma amplified sequence 3
BGLAP bone gamma-carboxyglutamate (gla) protein
CALCA calcitonin-related polypeptide alpha
CALCR calcitonin receptor
CASR calcium-sensing receptor
CCL27 chemokine (C-C motif) ligand 27
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLDN14 claudin 14
CSTB cystatin B (stefin B)
DGKH diacylglycerol kinase, eta
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FAM188B family with sequence similarity 188, member B
FBL fibrillarin
FTO fat mass and obesity associated
GCKR glucokinase (hexokinase 4) regulator
GGCX gamma-glutamyl carboxylase
GGT1 gamma-glutamyltransferase 1
GGTLC3 gamma-glutamyltransferase light chain 3
HAVCR1 hepatitis A virus cellular receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
INSRR insulin receptor-related receptor
KL klotho
LCN2 lipocalin 2
LPO lactoperoxidase
NAGLU N-acetylglucosaminidase, alpha
NAT10 N-acetyltransferase 10 (GCN5-related)
NBAS neuroblastoma amplified sequence
NQO1 NAD(P)H dehydrogenase, quinone 1
OGA O-GlcNAcase
PDILT protein disulfide isomerase-like, testis expressed
PDLIM3 PDZ and LIM domain 3
PKN1 protein kinase N1
PON1 paraoxonase 1
PTH parathyroid hormone
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS14 regulator of G-protein signaling 14
SCN7A sodium channel, voltage gated, type VII alpha subunit
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLPI secretory leukocyte peptidase inhibitor
SOD1 superoxide dismutase 1, soluble
SPP1 secreted phosphoprotein 1
TERT telomerase reverse transcriptase
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TRPV5 transient receptor potential cation channel, subfamily V, member 5
UMOD uromodulin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZNF365 zinc finger protein 365
ZNF410 zinc finger protein 410