Urticaria Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Urticaria is a kind of skin rash notable for pale red, raised, itchy bumps that might also cause a burning or stinging sensation. It is often but not necessarily caused by an allergic reaction. (Experimental Factor Ontology, EFO_0005531)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D014581
Similar Terms
Downloads & Tools

Genes

289 genes/proteins associated with the disease Urticaria from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.88009
IL18 interleukin 18 2.88009
VCAM1 vascular cell adhesion molecule 1 2.88009
HNMT histamine N-methyltransferase 2.88009
ALOX5 arachidonate 5-lipoxygenase 2.88009
ICAM1 intercellular adhesion molecule 1 2.88009
TNF tumor necrosis factor 2.88009
IL1B interleukin 1, beta 2.88009
MPO myeloperoxidase 2.88009
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.88009
GSTM1 glutathione S-transferase mu 1 2.88009
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 2.88009
SELE selectin E 2.88009
ALB albumin 2.88009
TGFB1 transforming growth factor, beta 1 2.88009
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 2.88009
IL6 interleukin 6 2.37992
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.3579
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.35532
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.26463
CXCL8 chemokine (C-X-C motif) ligand 8 2.25107
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.24372
NOS2 nitric oxide synthase 2, inducible 2.23462
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.20779
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.16758
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.15873
CAT catalase 2.13931
IL4 interleukin 4 2.1246
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.09765
BCL2 B-cell CLL/lymphoma 2 2.09765
BAX BCL2-associated X protein 2.09695
IL10 interleukin 10 2.09672
IFNG interferon, gamma 2.08906
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.06076
HRH1 histamine receptor H1 2.06015
CCL2 chemokine (C-C motif) ligand 2 2.05319
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.00703
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.98611
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.9369
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.91502
PPARG peroxisome proliferator-activated receptor gamma 1.91301
VEGFA vascular endothelial growth factor A 1.90738
FOS FBJ murine osteosarcoma viral oncogene homolog 1.90721
GSTP1 glutathione S-transferase pi 1 1.88704
REN renin 1.88243
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.87625
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.87443
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.87143
JUN jun proto-oncogene 1.86167
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.84162
DDIT3 DNA-damage-inducible transcript 3 1.83753
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.83396
MAPK3 mitogen-activated protein kinase 3 1.82115
CCL3 chemokine (C-C motif) ligand 3 1.81775
HMOX1 heme oxygenase 1 1.76597
MAPK1 mitogen-activated protein kinase 1 1.76347
SELL selectin L 1.7623
EGFR epidermal growth factor receptor 1.7619
MMP2 matrix metallopeptidase 2 1.75973
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.7074
FAS Fas cell surface death receptor 1.70471
CCND1 cyclin D1 1.70388
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.69867
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.69555
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.6857
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.67933
MMP9 matrix metallopeptidase 9 1.67718
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.67007
TP53 tumor protein p53 1.66921
TIMP1 TIMP metallopeptidase inhibitor 1 1.66921
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.6677
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.6606
SOD2 superoxide dismutase 2, mitochondrial 1.64146
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.63743
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.63116
CFLAR CASP8 and FADD-like apoptosis regulator 1.63116
IL5 interleukin 5 1.62758
BID BH3 interacting domain death agonist 1.62691
COL1A1 collagen, type I, alpha 1 1.62222
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 1.61529
CYCS cytochrome c, somatic 1.60082
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.58303
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.58279
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.57618
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.56828
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 1.5673
TIMP2 TIMP metallopeptidase inhibitor 2 1.56141
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.56044
EDN1 endothelin 1 1.55723
GSK3B glycogen synthase kinase 3 beta 1.54402
FASLG Fas ligand (TNF superfamily, member 6) 1.53431
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.53184
DHFR dihydrofolate reductase 1.52693
MMP13 matrix metallopeptidase 13 1.5108
GADD45A growth arrest and DNA-damage-inducible, alpha 1.50903
IL1A interleukin 1, alpha 1.50248
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.50069
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 1.49813
POMC proopiomelanocortin 1.48864
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.4871
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.48454
IGF1 insulin-like growth factor 1 (somatomedin C) 1.47736
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.47478
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.46883
PARP1 poly (ADP-ribose) polymerase 1 1.45511
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.45009
NPY neuropeptide Y 1.44273
BAK1 BCL2-antagonist/killer 1 1.43755
BCL2L1 BCL2-like 1 1.4351
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.42562
IL2 interleukin 2 1.42535
F3 coagulation factor III (thromboplastin, tissue factor) 1.42047
CCNB1 cyclin B1 1.41091
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.40595
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.40148
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.40008
ACTA2 actin, alpha 2, smooth muscle, aorta 1.3998
CD44 CD44 molecule (Indian blood group) 1.39451
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.39422
PPARA peroxisome proliferator-activated receptor alpha 1.39058
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.38974
KNG1 kininogen 1 1.38384
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.38355
NPPB natriuretic peptide B 1.3759
GCLC glutamate-cysteine ligase, catalytic subunit 1.37275
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.37132
NOS3 nitric oxide synthase 3 (endothelial cell) 1.37103
CDK2 cyclin-dependent kinase 2 1.37075
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.36076
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.35676
INSIG1 insulin induced gene 1 1.34983
DUSP1 dual specificity phosphatase 1 1.34752
NQO1 NAD(P)H dehydrogenase, quinone 1 1.34256
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.33287
CALCA calcitonin-related polypeptide alpha 1.32905
S100A9 S100 calcium binding protein A9 1.32786
GSTT1 glutathione S-transferase theta 1 1.32488
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.32369
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.31626
NFE2L2 nuclear factor, erythroid 2-like 2 1.31566
EGF epidermal growth factor 1.30666
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 1.30269
TIMP3 TIMP metallopeptidase inhibitor 3 1.29936
S100A8 S100 calcium binding protein A8 1.29936
PCNA proliferating cell nuclear antigen 1.29875
G6PD glucose-6-phosphate dehydrogenase 1.29688
GCLM glutamate-cysteine ligase, modifier subunit 1.29287
STAT1 signal transducer and activator of transcription 1, 91kDa 1.28889
BIRC5 baculoviral IAP repeat containing 5 1.28889
XDH xanthine dehydrogenase 1.28518
NPPA natriuretic peptide A 1.28518
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.28395
IL12B interleukin 12B 1.28088
MAPK14 mitogen-activated protein kinase 14 1.27782
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.26205
GAST gastrin 1.26175
COL3A1 collagen, type III, alpha 1 1.25432
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.25369
CREB1 cAMP responsive element binding protein 1 1.25338
GPX3 glutathione peroxidase 3 1.25183
PECAM1 platelet/endothelial cell adhesion molecule 1 1.24997
FASN fatty acid synthase 1.24623
CCL5 chemokine (C-C motif) ligand 5 1.2456
HSPA1A heat shock 70kDa protein 1A 1.24433
RB1 retinoblastoma 1 1.2393
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.23616
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.23584
NUPR1 nuclear protein, transcriptional regulator, 1 1.23456
TJP1 tight junction protein 1 1.22696
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.22696
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.22599
APP amyloid beta (A4) precursor protein 1.21887
SPP1 secreted phosphoprotein 1 1.21501
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.21304
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.20946
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.20784
H2AFX H2A histone family, member X 1.2059
PLAT plasminogen activator, tissue 1.2059
EGR1 early growth response 1 1.20427
IGF1R insulin-like growth factor 1 receptor 1.2013
AKR1C3 aldo-keto reductase family 1, member C3 1.19445
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.19213
MAPK8 mitogen-activated protein kinase 8 1.19047
FGF2 fibroblast growth factor 2 (basic) 1.19047
APAF1 apoptotic peptidase activating factor 1 1.19014
BBC3 BCL2 binding component 3 1.18751
THBS1 thrombospondin 1 1.18751
MCL1 myeloid cell leukemia 1 1.18293
TGFA transforming growth factor, alpha 1.17959
IL13 interleukin 13 1.17464
CKM creatine kinase, muscle 1.17235
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.17
ADIPOQ adiponectin, C1Q and collagen domain containing 1.17
DNASE1 deoxyribonuclease I 1.16666
GPX1 glutathione peroxidase 1 1.16236
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.1617
CCND3 cyclin D3 1.15899
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.15899
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 1.15627
COL18A1 collagen, type XVIII, alpha 1 1.15593
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.15357
HSPB1 heat shock 27kDa protein 1 1.15022
DCXR dicarbonyl/L-xylulose reductase 1.14919
HDC histidine decarboxylase 1.14816
POR P450 (cytochrome) oxidoreductase 1.14473
RHOB ras homolog family member B 1.14404
CXCL10 chemokine (C-X-C motif) ligand 10 1.14302
MAOA monoamine oxidase A 1.14132
F2R coagulation factor II (thrombin) receptor 1.14098
TAGLN transgelin 1.13827
KCNK2 potassium channel, two pore domain subfamily K, member 2 1.13552
NGFR nerve growth factor receptor 1.13245
CXCL2 chemokine (C-X-C motif) ligand 2 1.13007
TBX21 T-box 21 1.12805
C1S complement component 1, s subcomponent 1.12495
CCNA2 cyclin A2 1.12254
E2F1 E2F transcription factor 1 1.12219
IL12A interleukin 12A 1.12219
AKR1C2 aldo-keto reductase family 1, member C2 1.12219
MMP1 matrix metallopeptidase 1 1.11877
ASIC3 acid sensing (proton gated) ion channel 3 1.11639
GDF15 growth differentiation factor 15 1.10907
CES2 carboxylesterase 2 1.10907
SAT1 spermidine/spermine N1-acetyltransferase 1 1.10699
INHBE inhibin, beta E 1.10699
CAV1 caveolin 1, caveolae protein, 22kDa 1.10596
HBEGF heparin-binding EGF-like growth factor 1.10353
TLR4 toll-like receptor 4 1.10353
COL2A1 collagen, type II, alpha 1 1.10353
ACAN aggrecan 1.10069
GUSB glucuronidase, beta 1.09998
ATF3 activating transcription factor 3 1.09927
CLU clusterin 1.09576
SFTPB surfactant protein B 1.09471
DBT dihydrolipoamide branched chain transacylase E2 1.09401
HRAS Harvey rat sarcoma viral oncogene homolog 1.08833
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.08549
AKR1C1 aldo-keto reductase family 1, member C1 1.08372
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.08372
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.07911
GFAP glial fibrillary acidic protein 1.07269
ODC1 ornithine decarboxylase 1 1.07199
CHUK conserved helix-loop-helix ubiquitous kinase 1.07128
STAR steroidogenic acute regulatory protein 1.07022
TCF3 transcription factor 3 1.06881
CCNG1 cyclin G1 1.06588
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.0637
CREM cAMP responsive element modulator 1.05972
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 1.05936
MT1A metallothionein 1A 1.05793
GNG4 guanine nucleotide binding protein (G protein), gamma 4 1.05685
PLIN2 perilipin 2 1.05648
FOXO1 forkhead box O1 1.05648
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.05573
IRS1 insulin receptor substrate 1 1.05573
IGFBP3 insulin-like growth factor binding protein 3 1.05349
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.04721
LEP leptin 1.04314
LDLR low density lipoprotein receptor 1.04314
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.04314
FAAH fatty acid amide hydrolase 1.04276
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.04051
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.03939
POU2F1 POU class 2 homeobox 1 1.03939
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.03567
CLCN3 chloride channel, voltage-sensitive 3 1.03382
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.03308
AR androgen receptor 1.03159
CBR1 carbonyl reductase 1 1.03122
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.03084
LTA lymphotoxin alpha 1.03084
STAT5B signal transducer and activator of transcription 5B 1.02858
COL4A2 collagen, type IV, alpha 2 1.02858
FMO1 flavin containing monooxygenase 1 1.02821
CRP C-reactive protein, pentraxin-related 1.02708
HMGB1 high mobility group box 1 1.02522
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.02522
NGF nerve growth factor (beta polypeptide) 1.02485
PRL prolactin 1.02447
MKI67 marker of proliferation Ki-67 1.02299
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.02225
GNAS GNAS complex locus 1.01928
PGD phosphogluconate dehydrogenase 1.01928
HSPA8 heat shock 70kDa protein 8 1.01928
EIF2A eukaryotic translation initiation factor 2A, 65kDa 1.0189
CTGF connective tissue growth factor 1.01701
CTSL cathepsin L 1.01663
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.01625
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 1.01249