Urticaria Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Urticaria is a kind of skin rash notable for pale red, raised, itchy bumps that might also cause a burning or stinging sensation. It is often but not necessarily caused by an allergic reaction. (Experimental Factor Ontology, EFO_0005531)
External Link https://www.disgenet.org/browser/0/1/0/C0042109
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Genes

160 genes associated with the disease Urticaria in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACE angiotensin I converting enzyme
ADD2 adducin 2 (beta)
ADGRE2 adhesion G protein-coupled receptor E2
ADRB2 adrenoceptor beta 2, surface
AGRP agouti related neuropeptide
AGXT alanine-glyoxylate aminotransferase
ALB albumin
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5 arachidonate 5-lipoxygenase
ANTXR2 anthrax toxin receptor 2
ARSA arylsulfatase A
ARTN artemin
BST2 bone marrow stromal cell antigen 2
CAPS calcyphosine
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CAT catalase
CBS cystathionine-beta-synthase
CCL8 chemokine (C-C motif) ligand 8
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD28 CD28 molecule
CD38 CD38 molecule
CD63 CD63 molecule
CD68 CD68 molecule
CD9 CD9 molecule
CFB complement factor B
CHP1 calcineurin-like EF-hand protein 1
COL17A1 collagen, type XVII, alpha 1
COL1A1 collagen, type I, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
CP ceruloplasmin (ferroxidase)
CREB5 cAMP responsive element binding protein 5
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSD cathepsin D
CXCL8 chemokine (C-X-C motif) ligand 8
DGKG diacylglycerol kinase, gamma 90kDa
E2F1 E2F transcription factor 1
ELOVL4 ELOVL fatty acid elongase 4
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
F12 coagulation factor XII (Hageman factor)
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FLG filaggrin
FOXP3 forkhead box P3
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GPX1 glutathione peroxidase 1
GRK6 G protein-coupled receptor kinase 6
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HDC histidine decarboxylase
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HP haptoglobin
HPGDS hematopoietic prostaglandin D synthase
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IFNG interferon, gamma
IFT43 intraflagellar transport 43
IL10 interleukin 10
IL13 interleukin 13
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL31 interleukin 31
IL33 interleukin 33
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INA internexin neuronal intermediate filament protein, alpha
IRF1 interferon regulatory factor 1
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KNG1 kininogen 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LTC4S leukotriene C4 synthase
LY96 lymphocyte antigen 96
MAP2 microtubule-associated protein 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MARCHF1 membrane associated ring-CH-type finger 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEFV Mediterranean fever
METAP2 methionyl aminopeptidase 2
MPO myeloperoxidase
MVK mevalonate kinase
MYD88 myeloid differentiation primary response 88
NGF nerve growth factor (beta polypeptide)
NLRC4 NLR family, CARD domain containing 4
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NRSN1 neurensin 1
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRKCD protein kinase C, delta
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM45 RNA binding motif protein 45
RDX radixin
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SF3B4 splicing factor 3b, subunit 4, 49kDa
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMOC1 SPARC related modular calcium binding 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SPINK5 serine peptidase inhibitor, Kazal type 5
SST somatostatin
STAT1 signal transducer and activator of transcription 1, 91kDa
SYK spleen tyrosine kinase
SYN2 synapsin II
TGFB1 transforming growth factor, beta 1
TGFBR3 transforming growth factor, beta receptor III
TMED2 transmembrane emp24 domain trafficking protein 2
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPO thyroid peroxidase
TPPP tubulin polymerization promoting protein
TRPM8 transient receptor potential cation channel, subfamily M, member 8
VCAM1 vascular cell adhesion molecule 1
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1