Uterine leiomyoma_Uterus - Myometrium (MMHCC)_GSE593 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE593
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Genes

600 genes differentially expressed during Uterine leiomyoma_Uterus - Myometrium (MMHCC)_GSE593 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
COX7CP1 cytochrome c oxidase subunit VIIc pseudogene 1 3.40482
MRPL48 mitochondrial ribosomal protein L48 3.3185
RPL27 ribosomal protein L27 3.28877
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 3.2661
GOLGA7 golgin A7 3.22695
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 3.20042
PCNA proliferating cell nuclear antigen 3.18299
CDC16 cell division cycle 16 3.13408
PLXNB2 plexin B2 2.94366
POMP proteasome maturation protein 2.92793
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 2.9152
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 2.87288
H2AFZ H2A histone family, member Z 2.87106
GOSR1 golgi SNAP receptor complex member 1 2.8622
CNOT1 CCR4-NOT transcription complex, subunit 1 2.83376
RPS8 ribosomal protein S8 2.82075
RPS29 ribosomal protein S29 2.81244
C14ORF166 chromosome 14 open reading frame 166 2.81187
CTBP2 C-terminal binding protein 2 2.78308
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 2.78249
WDR45 WD repeat domain 45 2.76279
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 2.72117
FKBP3 FK506 binding protein 3, 25kDa 2.68269
RPS5 ribosomal protein S5 2.67045
SF3B5 splicing factor 3b, subunit 5, 10kDa 2.66691
C14ORF2 chromosome 14 open reading frame 2 2.64717
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 2.62022
TTC3 tetratricopeptide repeat domain 3 2.59378
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 2.59323
ITPK1 inositol-tetrakisphosphate 1-kinase 2.57438
METAP1 methionyl aminopeptidase 1 2.57252
ZNF250 zinc finger protein 250 2.54518
GOLGA5 golgin A5 2.52468
RRAGC Ras-related GTP binding C 2.50792
C11ORF58 chromosome 11 open reading frame 58 2.49802
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 2.48943
RPS27L ribosomal protein S27-like 2.46438
C7ORF49 chromosome 7 open reading frame 49 2.46337
CRTC1 CREB regulated transcription coactivator 1 2.43198
ANAPC5 anaphase promoting complex subunit 5 2.40791
LOC100506469 2.40591
EEF1B2 eukaryotic translation elongation factor 1 beta 2 2.40369
QARS glutaminyl-tRNA synthetase 2.39364
BRD3 bromodomain containing 3 2.38268
ACTN4 actinin, alpha 4 2.37582
ZMAT3 zinc finger, matrin-type 3 2.36791
NAV2 neuron navigator 2 2.35557
PGAP2 post-GPI attachment to proteins 2 2.34746
SOX4 SRY (sex determining region Y)-box 4 2.32335
ADSL adenylosuccinate lyase 2.3185
TMSB15A thymosin beta 15a 2.31368
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 2.28765
TRAPPC2L trafficking protein particle complex 2-like 2.28302
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 2.28148
CCDC73 coiled-coil domain containing 73 2.26637
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 2.23935
PHB2 prohibitin 2 2.22432
CSE1L CSE1 chromosome segregation 1-like (yeast) 2.20228
TAOK3 TAO kinase 3 2.20197
TRIM27 tripartite motif containing 27 2.19857
SLC38A1 solute carrier family 38, member 1 2.19737
EBNA1BP2 EBNA1 binding protein 2 2.19543
HYOU1 hypoxia up-regulated 1 2.19482
MRPS31 mitochondrial ribosomal protein S31 2.16689
GOLGA4 golgin A4 2.16442
UQCRH ubiquinol-cytochrome c reductase hinge protein 2.15794
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 2.14838
TULP4 tubby like protein 4 2.13246
ENAH enabled homolog (Drosophila) 2.12891
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 2.12605
UQCRB ubiquinol-cytochrome c reductase binding protein 2.10827
SEC61B Sec61 beta subunit 2.10243
TXNL1 thioredoxin-like 1 2.09932
SMS spermine synthase 2.09913
AMZ2 archaelysin family metallopeptidase 2 2.09528
OSGEP O-sialoglycoprotein endopeptidase 2.08224
HRSP12 heat-responsive protein 12 2.08113
ADGRA2 adhesion G protein-coupled receptor A2 2.07029
MPI mannose phosphate isomerase 2.06846
CCT4 chaperonin containing TCP1, subunit 4 (delta) 2.05547
PNN pinin, desmosome associated protein 2.05371
RPS7 ribosomal protein S7 2.05097
SIN3B SIN3 transcription regulator family member B 2.05091
LARS2 leucyl-tRNA synthetase 2, mitochondrial 2.04349
ZDHHC4 zinc finger, DHHC-type containing 4 2.04273
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 2.03416
NUP62 nucleoporin 62kDa 2.03214
SRI sorcin 2.02697
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 2.01818
RTEL1 regulator of telomere elongation helicase 1 2.00734
CBX1 chromobox homolog 1 2.00512
MAD2L1BP MAD2L1 binding protein 2.00416
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 1.99779
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 1.99765
RPS24 ribosomal protein S24 1.9976
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 1.98435
NAGK N-acetylglucosamine kinase 1.97693
MZT2B mitotic spindle organizing protein 2B 1.97636
CAPRIN2 caprin family member 2 1.97429
COL9A2 collagen, type IX, alpha 2 1.96388
YPEL5 yippee-like 5 (Drosophila) 1.9625
CUL2 cullin 2 1.94954
EMX2 empty spiracles homeobox 2 1.92351
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 1.91549
RPL36 ribosomal protein L36 1.91471
SAE1 SUMO1 activating enzyme subunit 1 1.90567
RBM6 RNA binding motif protein 6 1.90456
SEC11A SEC11 homolog A (S. cerevisiae) 1.90379
COPS2 COP9 signalosome subunit 2 1.90158
SETD5 SET domain containing 5 1.89282
UBE3A ubiquitin protein ligase E3A 1.89175
PLEKHJ1 pleckstrin homology domain containing, family J member 1 1.88657
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 1.86998
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.86672
DRG1 developmentally regulated GTP binding protein 1 1.86664
LDHB lactate dehydrogenase B 1.86505
MSRB2 methionine sulfoxide reductase B2 1.85946
ZFHX3 zinc finger homeobox 3 1.85865
BABAM1 BRISC and BRCA1 A complex member 1 1.85681
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 1.84933
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.8463
TPI1 triosephosphate isomerase 1 1.84558
ACOT13 acyl-CoA thioesterase 13 1.83414
EIF4E2 eukaryotic translation initiation factor 4E family member 2 1.82434
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 1.8235
WBP5 WW domain binding protein 5 1.81949
TRAPPC3 trafficking protein particle complex 3 1.80169
NHP2 NHP2 ribonucleoprotein 1.80155
COLEC12 collectin sub-family member 12 1.80052
COA3 cytochrome c oxidase assembly factor 3 1.79614
SYT11 synaptotagmin XI 1.78306
GOLGA3 golgin A3 1.78119
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 1.77581
USP21 ubiquitin specific peptidase 21 1.77113
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 1.77103
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 1.76657
RALBP1 ralA binding protein 1 1.76288
ATRN attractin 1.76151
PARP1 poly (ADP-ribose) polymerase 1 1.76075
GPX7 glutathione peroxidase 7 1.75841
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 1.75667
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.75632
PEG3 paternally expressed 3 1.75515
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.74442
INTS5 integrator complex subunit 5 1.73945
MAEA macrophage erythroblast attacher 1.72889
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.72828
STOML2 stomatin (EPB72)-like 2 1.72807
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1.72322
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 1.72294
RPL10A ribosomal protein L10a 1.721
MKRN1 makorin ring finger protein 1 1.71758
C19ORF53 chromosome 19 open reading frame 53 1.71706
WDR61 WD repeat domain 61 1.71668
HMGXB4 HMG box domain containing 4 1.71093
ZDHHC6 zinc finger, DHHC-type containing 6 1.70695
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 1.7046
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 1.69316
MAST4 microtubule associated serine/threonine kinase family member 4 1.69014
STRN4 striatin, calmodulin binding protein 4 1.68368
SNX17 sorting nexin 17 1.67504
RSL1D1 ribosomal L1 domain containing 1 1.6735
METTL22 methyltransferase like 22 1.6722
CKS2 CDC28 protein kinase regulatory subunit 2 1.66916
MZT2A mitotic spindle organizing protein 2A 1.66896
CALML3 calmodulin-like 3 1.66848
THOP1 thimet oligopeptidase 1 1.66518
FXN frataxin 1.65308
SCAND1 SCAN domain containing 1 1.64687
RPL39 ribosomal protein L39 1.64542
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 1.64029
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.63776
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.63624
GSTO1 glutathione S-transferase omega 1 1.63305
RPS20 ribosomal protein S20 1.63276
HMGB1 high mobility group box 1 1.63118
AHCYL1 adenosylhomocysteinase-like 1 1.61899
SET SET nuclear proto-oncogene 1.615
SEC31A SEC31 homolog A (S. cerevisiae) 1.61374
SCNM1 sodium channel modifier 1 1.61217
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 1.61168
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.61146
RBPMS RNA binding protein with multiple splicing 1.61127
COX7C cytochrome c oxidase subunit VIIc 1.61068
OPRL1 opiate receptor-like 1 1.60785
BZW2 basic leucine zipper and W2 domains 2 1.60781
TRO trophinin 1.60565
FAM96B family with sequence similarity 96, member B 1.60307
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 1.60268
MORF4L2 mortality factor 4 like 2 1.60252
SPOP speckle-type POZ protein 1.60215
ZNF692 zinc finger protein 692 1.60212
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 1.5985
TTLL5 tubulin tyrosine ligase-like family member 5 1.59654
AMT aminomethyltransferase 1.59555
RPSA ribosomal protein SA 1.59271
THYN1 thymocyte nuclear protein 1 1.59178
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 1.59173
CUEDC2 CUE domain containing 2 1.59055
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 1.58873
SDF2L1 stromal cell-derived factor 2-like 1 1.58304
COPB1 coatomer protein complex, subunit beta 1 1.58259
MPHOSPH9 M-phase phosphoprotein 9 1.58046
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 1.5795
COPS8 COP9 signalosome subunit 8 1.57824
CNPY2 canopy FGF signaling regulator 2 1.57779
JTB jumping translocation breakpoint 1.57272
GPC6 glypican 6 1.57192
ADGRL1 adhesion G protein-coupled receptor L1 1.56684
RPS9 ribosomal protein S9 1.56445
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 1.56091
FBXL7 F-box and leucine-rich repeat protein 7 1.5538
PDS5B PDS5 cohesin associated factor B 1.5529
TRIM28 tripartite motif containing 28 1.55282
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1.54525
MEN1 multiple endocrine neoplasia I 1.54393
ZNF500 zinc finger protein 500 1.54167
EGFL6 EGF-like-domain, multiple 6 1.53796
ZNHIT3 zinc finger, HIT-type containing 3 1.53708
TRPS1 trichorhinophalangeal syndrome I 1.53491
OXA1L oxidase (cytochrome c) assembly 1-like 1.53466
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 1.53041
RIT1 Ras-like without CAAX 1 1.5281
NINL ninein-like 1.52805
FBL fibrillarin 1.52703
PABPN1 poly(A) binding protein, nuclear 1 1.52472
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 1.51834
CCS copper chaperone for superoxide dismutase 1.51733
S100PBP S100P binding protein 1.50514
RWDD2A RWD domain containing 2A 1.50404
RPS16 ribosomal protein S16 1.50223
RPL7 ribosomal protein L7 1.50174
TUG1 taurine up-regulated 1 (non-protein coding) 1.50029
PDGFC platelet derived growth factor C 1.49497
GTPBP8 GTP-binding protein 8 (putative) 1.48906
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 1.48657
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 1.48264
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 1.48193
PFDN5 prefoldin subunit 5 1.4807
KCTD15 potassium channel tetramerization domain containing 15 1.47659
LSM1 LSM1, U6 small nuclear RNA associated 1.4757
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 1.47552
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 1.47091
RBMX2 RNA binding motif protein, X-linked 2 1.4695
CHD8 chromodomain helicase DNA binding protein 8 1.46804
RNF7 ring finger protein 7 1.46591
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 1.46563
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.46303
ZBED5 zinc finger, BED-type containing 5 1.45572
FEN1 flap structure-specific endonuclease 1 1.45466
RPL3 ribosomal protein L3 1.45454
SFRP4 secreted frizzled-related protein 4 1.45243
RAP1B RAP1B, member of RAS oncogene family 1.4513
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 1.45031
EIF3B eukaryotic translation initiation factor 3, subunit B 1.44637
SLIT1 slit homolog 1 (Drosophila) 1.44199
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 1.43294
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 1.43009
SOD1 superoxide dismutase 1, soluble 1.43002
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 1.4291
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 1.42908
MRPS35 mitochondrial ribosomal protein S35 1.42401
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 1.41781
RPL28 ribosomal protein L28 1.41747
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 1.417
MOSPD1 motile sperm domain containing 1 1.41602
INPP5F inositol polyphosphate-5-phosphatase F 1.41199
BRMS1 breast cancer metastasis suppressor 1 1.41153
SLC46A3 solute carrier family 46, member 3 1.41054
CYFIP2 cytoplasmic FMR1 interacting protein 2 1.40815
GFRA4 GDNF family receptor alpha 4 1.40652
GSTP1 glutathione S-transferase pi 1 1.40526
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa 1.40301
OSBPL1A oxysterol binding protein-like 1A 1.40085
LRRC2 leucine rich repeat containing 2 1.39743
DDB2 damage-specific DNA binding protein 2, 48kDa 1.39307
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 1.39044
LCAT lecithin-cholesterol acyltransferase 1.38821
PHACTR4 phosphatase and actin regulator 4 1.38632
MRPS33 mitochondrial ribosomal protein S33 1.3844
DENND6B DENN/MADD domain containing 6B 1.38401
SFRP1 secreted frizzled-related protein 1 1.38371
R3HCC1 R3H domain and coiled-coil containing 1 1.3796
PXMP2 peroxisomal membrane protein 2, 22kDa 1.37549
SDF2 stromal cell-derived factor 2 1.37222
TLN2 talin 2 1.36873
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.36581
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 1.36558
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1.36264
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.36029
NHLH1 nescient helix loop helix 1 1.36027
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.3574
COL6A3 collagen, type VI, alpha 3 1.35729
P3H3 prolyl 3-hydroxylase 3 1.35726
TLE4 transducin-like enhancer of split 4 1.35507
SF3A3 splicing factor 3a, subunit 3, 60kDa 1.35396
CCDC130 coiled-coil domain containing 130 1.35218
IMMT inner membrane protein, mitochondrial 1.34661
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 1.34112
GMPR2 guanosine monophosphate reductase 2 1.34072

decreased expression

Symbol Name Standardized Value
TGOLN2 trans-golgi network protein 2 -3.70827
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -3.50298
ANXA1 annexin A1 -3.48139
C1S complement component 1, s subcomponent -3.40868
STX10 syntaxin 10 -3.38075
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -3.21004
EPAS1 endothelial PAS domain protein 1 -3.18789
TMEM109 transmembrane protein 109 -3.00247
MPZL1 myelin protein zero-like 1 -2.92412
WDR37 WD repeat domain 37 -2.90396
ICAM2 intercellular adhesion molecule 2 -2.84836
HLA-E major histocompatibility complex, class I, E -2.83431
BAG3 BCL2-associated athanogene 3 -2.829
WFS1 Wolfram syndrome 1 (wolframin) -2.81776
IGFBP6 insulin-like growth factor binding protein 6 -2.76448
ADCY3 adenylate cyclase 3 -2.74758
PRKCH protein kinase C, eta -2.6986
REEP5 receptor accessory protein 5 -2.67851
PLEKHO2 pleckstrin homology domain containing, family O member 2 -2.66976
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.66923
IMP3 IMP3, U3 small nucleolar ribonucleoprotein -2.62851
BCL2L2 BCL2-like 2 -2.60823
RAB27A RAB27A, member RAS oncogene family -2.56062
SERINC3 serine incorporator 3 -2.53063
MAOB monoamine oxidase B -2.51365
TNS2 tensin 2 -2.4868
PEA15 phosphoprotein enriched in astrocytes 15 -2.45772
RPL22L1 ribosomal protein L22-like 1 -2.44069
NPDC1 neural proliferation, differentiation and control, 1 -2.42601
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.39118
CYB5R1 cytochrome b5 reductase 1 -2.38302
PRKD2 protein kinase D2 -2.37985
WDFY3 WD repeat and FYVE domain containing 3 -2.37731
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -2.37461
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -2.37144
CCNI cyclin I -2.36812
FAM20B family with sequence similarity 20, member B -2.35129
CFLAR CASP8 and FADD-like apoptosis regulator -2.32968
TAGLN2 transgelin 2 -2.32216
TOR3A torsin family 3, member A -2.306
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.27397
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -2.26459
STAT5B signal transducer and activator of transcription 5B -2.26297
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -2.26114
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -2.24521
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.21598
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.20537
ZFX zinc finger protein, X-linked -2.20404
CD81 CD81 molecule -2.20222
IFNGR1 interferon gamma receptor 1 -2.19713
DUSP6 dual specificity phosphatase 6 -2.19608
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -2.1726
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -2.1641
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) -2.13559
AAMP angio-associated, migratory cell protein -2.11635
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -2.08053
MGLL monoglyceride lipase -2.07854
GJA4 gap junction protein, alpha 4, 37kDa -2.07685
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -2.05006
EPS15 epidermal growth factor receptor pathway substrate 15 -2.04242
AP2B1 adaptor-related protein complex 2, beta 1 subunit -2.01183
ADAR adenosine deaminase, RNA-specific -2.00609
INPP5K inositol polyphosphate-5-phosphatase K -2.00496
FAM189A2 family with sequence similarity 189, member A2 -2.00065
JAK1 Janus kinase 1 -1.99964
ASPH aspartate beta-hydroxylase -1.99269
ANGPTL2 angiopoietin-like 2 -1.98438
RALB v-ral simian leukemia viral oncogene homolog B -1.97656
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -1.96829
NSFL1C NSFL1 (p97) cofactor (p47) -1.96706
EMCN endomucin -1.96161
FAM171A1 family with sequence similarity 171, member A1 -1.95715
NDRG1 N-myc downstream regulated 1 -1.95433
GABPA GA binding protein transcription factor, alpha subunit 60kDa -1.94701
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -1.9434
RAB11A RAB11A, member RAS oncogene family -1.9424
GALT galactose-1-phosphate uridylyltransferase -1.93906
LAMB2 laminin, beta 2 (laminin S) -1.93793
SMAD2 SMAD family member 2 -1.92836
MALL mal, T-cell differentiation protein-like -1.92342
SETD8 SET domain containing (lysine methyltransferase) 8 -1.91905
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa -1.91751
SAFB2 scaffold attachment factor B2 -1.91585
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene -1.9157
PXN paxillin -1.91275
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -1.90657
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -1.90494
NCOA3 nuclear receptor coactivator 3 -1.90266
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -1.89879
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -1.89746
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -1.88952
SOX13 SRY (sex determining region Y)-box 13 -1.88146
MLX MLX, MAX dimerization protein -1.87772
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -1.8685
CD93 CD93 molecule -1.85929
CSF1 colony stimulating factor 1 (macrophage) -1.85681
CPD carboxypeptidase D -1.85627
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -1.84581
SFXN3 sideroflexin 3 -1.83046
CPQ carboxypeptidase Q -1.82958
MAPK14 mitogen-activated protein kinase 14 -1.82793
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -1.82103
FAM65B family with sequence similarity 65, member B -1.82078
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -1.8119
SON SON DNA binding protein -1.81053
TRAF3 TNF receptor-associated factor 3 -1.80578
PLA2G12A phospholipase A2, group XIIA -1.79822
LARP7 La ribonucleoprotein domain family, member 7 -1.79436
GLB1 galactosidase, beta 1 -1.79314
LIMA1 LIM domain and actin binding 1 -1.791
SDC4 syndecan 4 -1.78982
CDR2 cerebellar degeneration-related protein 2, 62kDa -1.78913
GAPVD1 GTPase activating protein and VPS9 domains 1 -1.7834
CREG1 cellular repressor of E1A-stimulated genes 1 -1.78196
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -1.78179
RHOT2 ras homolog family member T2 -1.78013
CRLF3 cytokine receptor-like factor 3 -1.77898
SOD3 superoxide dismutase 3, extracellular -1.77711
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -1.77563
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -1.77217
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 -1.76696
AGPS alkylglycerone phosphate synthase -1.76624
RNGTT RNA guanylyltransferase and 5'-phosphatase -1.76086
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -1.75393
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -1.75191
ECM1 extracellular matrix protein 1 -1.74671
CAST calpastatin -1.74183
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -1.74046
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -1.74003
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -1.73774
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.72113
CLEC3B C-type lectin domain family 3, member B -1.71719
BMS1 BMS1 ribosome biogenesis factor -1.71244
CCND3 cyclin D3 -1.70875
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -1.70664
PBX2 pre-B-cell leukemia homeobox 2 -1.70476
CSNK1G3 casein kinase 1, gamma 3 -1.70274
MFN2 mitofusin 2 -1.70168
SPON1 spondin 1, extracellular matrix protein -1.70008
APP amyloid beta (A4) precursor protein -1.69781
RAD23B RAD23 homolog B (S. cerevisiae) -1.69524
JAG2 jagged 2 -1.69226
ANXA2 annexin A2 -1.69084
WWTR1 WW domain containing transcription regulator 1 -1.68573
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -1.6672
DCTN5 dynactin 5 (p25) -1.66702
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -1.66375
TOR1AIP1 torsin A interacting protein 1 -1.66154
EHD1 EH-domain containing 1 -1.6563
LMCD1 LIM and cysteine-rich domains 1 -1.65322
CHMP3 charged multivesicular body protein 3 -1.64734
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -1.64034
AES amino-terminal enhancer of split -1.63483
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) -1.63352
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -1.63119
CDC42SE1 CDC42 small effector 1 -1.63001
GBP1 guanylate binding protein 1, interferon-inducible -1.62969
EMP1 epithelial membrane protein 1 -1.62717
ECH1 enoyl CoA hydratase 1, peroxisomal -1.61866
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -1.61545
CD59 CD59 molecule, complement regulatory protein -1.61335
TIAM1 T-cell lymphoma invasion and metastasis 1 -1.61221
THBD thrombomodulin -1.61023
TCF12 transcription factor 12 -1.60943
BCL6 B-cell CLL/lymphoma 6 -1.60448
AKAP12 A kinase (PRKA) anchor protein 12 -1.60421
LTBP4 latent transforming growth factor beta binding protein 4 -1.59321
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -1.59042
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -1.58805
TMBIM6 transmembrane BAX inhibitor motif containing 6 -1.58704
CLIP4 CAP-GLY domain containing linker protein family, member 4 -1.58578
TMEM9B TMEM9 domain family, member B -1.58532
KLHL2 kelch-like family member 2 -1.58226
GPNMB glycoprotein (transmembrane) nmb -1.57925
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -1.57601
TOR1A torsin family 1, member A (torsin A) -1.57468
AKIRIN1 akirin 1 -1.57061
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -1.56943
TUBB4B tubulin, beta 4B class IVb -1.56722
PGS1 phosphatidylglycerophosphate synthase 1 -1.56613
MYO5C myosin VC -1.56342
CYFIP1 cytoplasmic FMR1 interacting protein 1 -1.55773
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -1.55725
CAB39 calcium binding protein 39 -1.55507
AGTR1 angiotensin II receptor, type 1 -1.55285
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -1.55072
PTTG1IP pituitary tumor-transforming 1 interacting protein -1.55023
UTRN utrophin -1.54467
UGP2 UDP-glucose pyrophosphorylase 2 -1.53854
FOXJ2 forkhead box J2 -1.53376
FUCA1 fucosidase, alpha-L- 1, tissue -1.53229
TRIM38 tripartite motif containing 38 -1.53093
LRP5 low density lipoprotein receptor-related protein 5 -1.53073
PDCD6IP programmed cell death 6 interacting protein -1.52652
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -1.52308
CFI complement factor I -1.52259
S100A4 S100 calcium binding protein A4 -1.51953
VLDLR very low density lipoprotein receptor -1.51841
TM9SF1 transmembrane 9 superfamily member 1 -1.50813
GSN gelsolin -1.50706
DCTN4 dynactin 4 (p62) -1.50531
ELF1 E74-like factor 1 (ets domain transcription factor) -1.50358
KYNU kynureninase -1.50224
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 -1.50159
EML4 echinoderm microtubule associated protein like 4 -1.50043
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) -1.49985
TMED5 transmembrane emp24 protein transport domain containing 5 -1.49971
CEP290 centrosomal protein 290kDa -1.49954
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -1.49893
BIRC2 baculoviral IAP repeat containing 2 -1.49469
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -1.49457
INPP1 inositol polyphosphate-1-phosphatase -1.49378
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -1.49309
MIR22HG MIR22 host gene -1.48296
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -1.48267
KIAA0355 KIAA0355 -1.47651
TMBIM1 transmembrane BAX inhibitor motif containing 1 -1.47296
CARD10 caspase recruitment domain family, member 10 -1.47263
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -1.47098
C1R complement component 1, r subcomponent -1.46771
AXL AXL receptor tyrosine kinase -1.46594
FGFR3 fibroblast growth factor receptor 3 -1.46554
STEAP4 STEAP family member 4 -1.46527
OSGIN2 oxidative stress induced growth inhibitor family member 2 -1.46232
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -1.45895
NQO2 NAD(P)H dehydrogenase, quinone 2 -1.45747
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -1.45723
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -1.45601
CALCOCO2 calcium binding and coiled-coil domain 2 -1.45578
MAX MYC associated factor X -1.45337
LINC00094 long intergenic non-protein coding RNA 94 -1.44488
MKNK2 MAP kinase interacting serine/threonine kinase 2 -1.44393
SYNE2 spectrin repeat containing, nuclear envelope 2 -1.43983
RIC8B RIC8 guanine nucleotide exchange factor B -1.43899
EGFL7 EGF-like-domain, multiple 7 -1.4346
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -1.43224
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -1.43057
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -1.42988
LGALS3 lectin, galactoside-binding, soluble, 3 -1.42767
HTT huntingtin -1.42595
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -1.42493
EGR1 early growth response 1 -1.42306
RUSC1 RUN and SH3 domain containing 1 -1.42219
ASS1 argininosuccinate synthase 1 -1.42021
GYS1 glycogen synthase 1 (muscle) -1.41926
VCP valosin containing protein -1.41875
SRGN serglycin -1.41668
PODXL podocalyxin-like -1.41352
SERP1 stress-associated endoplasmic reticulum protein 1 -1.41335
FLII flightless I homolog (Drosophila) -1.41268
IL15 interleukin 15 -1.41257
PREPL prolyl endopeptidase-like -1.41059
CKLF chemokine-like factor -1.41004
USP16 ubiquitin specific peptidase 16 -1.40702
MAPT microtubule-associated protein tau -1.40687
G0S2 G0/G1 switch 2 -1.40363
CAB39L calcium binding protein 39-like -1.40126
GRB10 growth factor receptor-bound protein 10 -1.40115
LMBRD1 LMBR1 domain containing 1 -1.40011
SETD3 SET domain containing 3 -1.3984
MFGE8 milk fat globule-EGF factor 8 protein -1.39314
KDR kinase insert domain receptor -1.39119
MAP4 microtubule-associated protein 4 -1.39118
CDK13 cyclin-dependent kinase 13 -1.38554
FAM63B family with sequence similarity 63, member B -1.38295
LIPA lipase A, lysosomal acid, cholesterol esterase -1.37792
MAT2B methionine adenosyltransferase II, beta -1.37746
WBP4 WW domain binding protein 4 -1.3754
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 -1.37506
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -1.37437
BCL3 B-cell CLL/lymphoma 3 -1.37285
TEX2 testis expressed 2 -1.37062
SLK STE20-like kinase -1.3704
NPR1 natriuretic peptide receptor 1 -1.36877
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -1.36866
PLA2G16 phospholipase A2, group XVI -1.36666
SEP15 15 kDa selenoprotein -1.3658
NOV nephroblastoma overexpressed -1.36454
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -1.36199
EXTL3 exostosin-like glycosyltransferase 3 -1.35884
SCAMP1 secretory carrier membrane protein 1 -1.35664
UNC13B unc-13 homolog B (C. elegans) -1.35645
HCFC1 host cell factor C1 -1.35531
CD34 CD34 molecule -1.35005
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -1.34906
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -1.3485
INHBB inhibin, beta B -1.34843
RTN3 reticulon 3 -1.34645
IFI27 interferon, alpha-inducible protein 27 -1.34621
IL6ST interleukin 6 signal transducer -1.34586
ZDHHC7 zinc finger, DHHC-type containing 7 -1.34294
GABARAPL1 GABA(A) receptor-associated protein like 1 -1.3423
WDR1 WD repeat domain 1 -1.34098
MCF2L MCF.2 cell line derived transforming sequence-like -1.339
ADD1 adducin 1 (alpha) -1.33872
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.33687
TMEM59 transmembrane protein 59 -1.33456
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -1.33402
TLE2 transducin-like enhancer of split 2 -1.33151
TRIM26 tripartite motif containing 26 -1.33116