V(D)J recombination Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). (Gene Ontology, GO_0033151)
External Link	http://amigo.geneontology.org/amigo/term/GO:0033151
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Genes

13 genes participating in the V(D)J recombination biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
CYREN	cell cycle regulator of NHEJ
DCAF1	DDB1 and CUL4 associated factor 1
HMGB1	high mobility group box 1
HMGB2	high mobility group box 2
LIG4	ligase IV, DNA, ATP-dependent
LRIG1	leucine-rich repeats and immunoglobulin-like domains 1
LRIG3	leucine-rich repeats and immunoglobulin-like domains 3
NHEJ1	nonhomologous end-joining factor 1
PRKDC	protein kinase, DNA-activated, catalytic polypeptide
RAG1	recombination activating gene 1
RAG2	recombination activating gene 2
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)
XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4