VAL Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

375 genes mutated in the VAL cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
A1CF APOBEC1 complementation factor
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADAM2 ADAM metallopeptidase domain 2
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTSL1 ADAMTS-like 1
ADAMTSL2 ADAMTS-like 2
ADCY6 adenylate cyclase 6
ADGRB3 adhesion G protein-coupled receptor B3
ADGRV1 adhesion G protein-coupled receptor V1
AKAP9 A kinase (PRKA) anchor protein 9
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMER3 APC membrane recruitment protein 3
ANAPC1 anaphase promoting complex subunit 1
ANKRD18B ankyrin repeat domain 18B
ANKRD36C ankyrin repeat domain 36C
ANKRD42 ankyrin repeat domain 42
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APP amyloid beta (A4) precursor protein
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP29 Rho GTPase activating protein 29
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASCC2 activating signal cointegrator 1 complex subunit 2
ASXL3 additional sex combs like transcriptional regulator 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AXDND1 axonemal dynein light chain domain containing 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCORL1 BCL6 corepressor-like 1
BCR breakpoint cluster region
BMP2KL BMP2 inducible kinase-like, pseudogene
BOC BOC cell adhesion associated, oncogene regulated
BRCA2 breast cancer 2, early onset
BRPF1 bromodomain and PHD finger containing, 1
C1QTNF5 C1q and tumor necrosis factor related protein 5
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CARD8 caspase recruitment domain family, member 8
CASR calcium-sensing receptor
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBWD6 COBW domain containing 6
CCDC132 coiled-coil domain containing 132
CCDC150 coiled-coil domain containing 150
CCDC90B coiled-coil domain containing 90B
CCNB3 cyclin B3
CDCP2 CUB domain containing protein 2
CDH23 cadherin-related 23
CDH7 cadherin 7, type 2
CDK11A cyclin-dependent kinase 11A
CDK11B cyclin-dependent kinase 11B
CEP70 centrosomal protein 70kDa
CFHR4 complement factor H-related 4
CHD7 chromodomain helicase DNA binding protein 7
CHPT1 choline phosphotransferase 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLEC16A C-type lectin domain family 16, member A
CNPY3 canopy FGF signaling regulator 3
CNTNAP3B contactin associated protein-like 3B
COA3 cytochrome c oxidase assembly factor 3
COG7 component of oligomeric golgi complex 7
COL20A1 collagen, type XX, alpha 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COPB1 coatomer protein complex, subunit beta 1
COPG1 coatomer protein complex, subunit gamma 1
CPA2 carboxypeptidase A2 (pancreatic)
CREBBP CREB binding protein
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTH cystathionine gamma-lyase
CTNS cystinosin, lysosomal cystine transporter
CUL9 cullin 9
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
D2HGDH D-2-hydroxyglutarate dehydrogenase
DCDC2C doublecortin domain containing 2C
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDX12P DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene
DENND5B DENN/MADD domain containing 5B
DGKB diacylglycerol kinase, beta 90kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
DISP2 dispatched homolog 2 (Drosophila)
DMAP1 DNA methyltransferase 1 associated protein 1
DNAH10 dynein, axonemal, heavy chain 10
DNAH3 dynein, axonemal, heavy chain 3
DNAH5 dynein, axonemal, heavy chain 5
DNASE1L2 deoxyribonuclease I-like 2
DOCK10 dedicator of cytokinesis 10
DSCAML1 Down syndrome cell adhesion molecule like 1
DST dystonin
DTX3L deltex 3 like, E3 ubiquitin ligase
DUSP10 dual specificity phosphatase 10
DUSP16 dual specificity phosphatase 16
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
DYSF dysferlin
ECT2 epithelial cell transforming 2
EDNRA endothelin receptor type A
ELL elongation factor RNA polymerase II
ELMO1 engulfment and cell motility 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHA1 EPH receptor A1
EPHA6 EPH receptor A6
ERBB4 erb-b2 receptor tyrosine kinase 4
ESYT2 extended synaptotagmin-like protein 2
EVC Ellis van Creveld protein
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM13B family with sequence similarity 13, member B
FAM160B2 family with sequence similarity 160, member B2
FAM35A family with sequence similarity 35, member A
FES FES proto-oncogene, tyrosine kinase
FKBP9 FK506 binding protein 9, 63 kDa
FLT1 fms-related tyrosine kinase 1
FMN2 formin 2
FMNL3 formin-like 3
FSTL4 follistatin-like 4
FUBP1 far upstream element (FUSE) binding protein 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAS2L1 growth arrest-specific 2 like 1
GAS2L3 growth arrest-specific 2 like 3
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GIF gastric intrinsic factor (vitamin B synthesis)
GLA galactosidase, alpha
GLB1L3 galactosidase, beta 1-like 3
GLTSCR2 glioma tumor suppressor candidate region gene 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPER1 G protein-coupled estrogen receptor 1
GPR143 G protein-coupled receptor 143
GPR161 G protein-coupled receptor 161
GPR83 G protein-coupled receptor 83
GRAP2 GRB2-related adaptor protein 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GTSF1L gametocyte specific factor 1-like
HEPHL1 hephaestin-like 1
HIST1H1B histone cluster 1, H1b
HIST1H2BO histone cluster 1, H2bo
HIST1H3D histone cluster 1, H3d
HIST1H4B histone cluster 1, H4b
HIST2H2BE histone cluster 2, H2be
HLA-C major histocompatibility complex, class I, C
HMCN1 hemicentin 1
HS1BP3 HCLS1 binding protein 3
HSPA2 heat shock 70kDa protein 2
HVCN1 hydrogen voltage gated channel 1
HYAL2 hyaluronoglucosaminidase 2
ICA1 islet cell autoantigen 1, 69kDa
ICAM2 intercellular adhesion molecule 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1
IGLL5 immunoglobulin lambda-like polypeptide 5
IL18RAP interleukin 18 receptor accessory protein
INSL6 insulin-like 6
IQCF1 IQ motif containing F1
IRF3 interferon regulatory factor 3
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KAT6A K(lysine) acetyltransferase 6A
KATNAL2 katanin p60 subunit A-like 2
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KDM2A lysine (K)-specific demethylase 2A
KDR kinase insert domain receptor
KIAA1429 KIAA1429
KIAA1671 KIAA1671
KLHL30 kelch-like family member 30
KLHL6 kelch-like family member 6
KRTAP5-2 keratin associated protein 5-2
LACTB2 lactamase, beta 2
LCOR ligand dependent nuclear receptor corepressor
LIMD1 LIM domains containing 1
LPIN1 lipin 1
LRP1B low density lipoprotein receptor-related protein 1B
LRP2 low density lipoprotein receptor-related protein 2
LRRC4B leucine rich repeat containing 4B
LTBP3 latent transforming growth factor beta binding protein 3
MAGEC1 melanoma antigen family C1
MAP2K3 mitogen-activated protein kinase kinase 3
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MDN1 MDN1, midasin homolog (yeast)
MEGF8 multiple EGF-like-domains 8
MGAM maltase-glucoamylase
MMP2 matrix metallopeptidase 2
MUC16 mucin 16, cell surface associated
MUC21 mucin 21, cell surface associated
MUC4 mucin 4, cell surface associated
MYADM myeloid-associated differentiation marker
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO18B myosin XVIIIB
MYRIP myosin VIIA and Rab interacting protein
MZF1 myeloid zinc finger 1
NAMPTP1 nicotinamide phosphoribosyltransferase pseudogene 1
NCAM1 neural cell adhesion molecule 1
NCAM2 neural cell adhesion molecule 2
NEB nebulin
NEU2 sialidase 2 (cytosolic sialidase)
NEUROD4 neuronal differentiation 4
NEUROG2 neurogenin 2
NFE2L3 nuclear factor, erythroid 2-like 3
NFIB nuclear factor I/B
NOD2 nucleotide-binding oligomerization domain containing 2
NPC1L1 NPC1-like 1
NR2C2AP nuclear receptor 2C2-associated protein
NRAP nebulin-related anchoring protein
NSDHL NAD(P) dependent steroid dehydrogenase-like
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP54 nucleoporin 54kDa
OGN osteoglycin
OPA1 optic atrophy 1 (autosomal dominant)
OR13J1 olfactory receptor, family 13, subfamily J, member 1
OR52K1 olfactory receptor, family 52, subfamily K, member 1
OR5H15 olfactory receptor, family 5, subfamily H, member 15
OR6C4 olfactory receptor, family 6, subfamily C, member 4
OTX2 orthodenticle homeobox 2
PAAF1 proteasomal ATPase-associated factor 1
PACS2 phosphofurin acidic cluster sorting protein 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCDHA4 protocadherin alpha 4
PCDHB13 protocadherin beta 13
PCSK5 proprotein convertase subtilisin/kexin type 5
PEX5 peroxisomal biogenesis factor 5
PHF20 PHD finger protein 20
PHKA2 phosphorylase kinase, alpha 2 (liver)
PIGM phosphatidylinositol glycan anchor biosynthesis, class M
PISD phosphatidylserine decarboxylase
PITPNB phosphatidylinositol transfer protein, beta
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PKDREJ polycystin (PKD) family receptor for egg jelly
PKP4 plakophilin 4
PLIN2 perilipin 2
PLIN4 perilipin 4
PLXNA3 plexin A3
PNLIPRP3 pancreatic lipase-related protein 3
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POMT2 protein-O-mannosyltransferase 2
POTEH POTE ankyrin domain family, member H
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRDM14 PR domain containing 14
PROM2 prominin 2
PRRC2A proline-rich coiled-coil 2A
PTER phosphotriesterase related
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRK protein tyrosine phosphatase, receptor type, K
PTPRT protein tyrosine phosphatase, receptor type, T
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
PXMP2 peroxisomal membrane protein 2, 22kDa
RAB11FIP4 RAB11 family interacting protein 4 (class II)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RANBP2 RAN binding protein 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAVER2 ribonucleoprotein, PTB-binding 2
RCAN3 RCAN family member 3
RGPD3 RANBP2-like and GRIP domain containing 3
RINT1 RAD50 interactor 1
RNF152 ring finger protein 152
RNF212 ring finger protein 212
RNF216 ring finger protein 216
RPH3A rabphilin 3A
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SALL1 spalt-like transcription factor 1
SART1 squamous cell carcinoma antigen recognized by T cells
SATB1 SATB homeobox 1
SCN3A sodium channel, voltage gated, type III alpha subunit
SDCCAG8 serologically defined colon cancer antigen 8
SESTD1 SEC14 and spectrin domains 1
SETD5 SET domain containing 5
SH3PXD2A SH3 and PX domains 2A
SI sucrase-isomaltase (alpha-glucosidase)
SIVA1 SIVA1, apoptosis-inducing factor
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC22A24 solute carrier family 22, member 24
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2
SLC38A4 solute carrier family 38, member 4
SLC39A5 solute carrier family 39 (zinc transporter), member 5
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMAP1 small ArfGAP 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SNX31 sorting nexin 31
SOGA1 suppressor of glucose, autophagy associated 1
SPAG8 sperm associated antigen 8
SPATA6 spermatogenesis associated 6
SPINK5 serine peptidase inhibitor, Kazal type 5
SREBF2 sterol regulatory element binding transcription factor 2
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SSH3 slingshot protein phosphatase 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST18 suppression of tumorigenicity 18, zinc finger
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STARD3 StAR-related lipid transfer (START) domain containing 3
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STRADA STE20-related kinase adaptor alpha
STRN striatin, calmodulin binding protein
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
SYNJ2 synaptojanin 2
SYT1 synaptotagmin I
SZT2 seizure threshold 2 homolog (mouse)
TAS2R16 taste receptor, type 2, member 16
TBC1D17 TBC1 domain family, member 17
TCEAL6 transcription elongation factor A (SII)-like 6
TCF3 transcription factor 3
TDRD5 tudor domain containing 5
TECPR1 tectonin beta-propeller repeat containing 1
TG thyroglobulin
TLE2 transducin-like enhancer of split 2
TMC1 transmembrane channel-like 1
TMEM136 transmembrane protein 136
TMEM53 transmembrane protein 53
TMPRSS2 transmembrane protease, serine 2
TNRC6B trinucleotide repeat containing 6B
TPO thyroid peroxidase
TRAM1 translocation associated membrane protein 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC27 tetratricopeptide repeat domain 27
TTC30B tetratricopeptide repeat domain 30B
TTC39B tetratricopeptide repeat domain 39B
TTN titin
TUSC3 tumor suppressor candidate 3
TWISTNB TWIST neighbor
TXNRD3 thioredoxin reductase 3
UBA1 ubiquitin-like modifier activating enzyme 1
UBE2U ubiquitin-conjugating enzyme E2U (putative)
UBE4B ubiquitination factor E4B
UBXN4 UBX domain protein 4
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UMODL1 uromodulin-like 1
UNKL unkempt family zinc finger-like
UROC1 urocanate hydratase 1
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP17L2 ubiquitin specific peptidase 17-like family member 2
VENTX VENT homeobox
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WDR33 WD repeat domain 33
WDR36 WD repeat domain 36
WNT2 wingless-type MMTV integration site family member 2
XPO4 exportin 4
XPO7 exportin 7
YTHDC2 YTH domain containing 2
ZBTB33 zinc finger and BTB domain containing 33
ZCCHC11 zinc finger, CCHC domain containing 11
ZFP91 ZFP91 zinc finger protein
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZFX zinc finger protein, X-linked
ZNF12 zinc finger protein 12
ZNF157 zinc finger protein 157
ZNF160 zinc finger protein 160
ZNF354B zinc finger protein 354B
ZNF408 zinc finger protein 408
ZNF430 zinc finger protein 430
ZNF516 zinc finger protein 516
ZNF552 zinc finger protein 552
ZNF618 zinc finger protein 618
ZNF708 zinc finger protein 708
ZNF836 zinc finger protein 836
ZNF845 zinc finger protein 845
ZNF91 zinc finger protein 91
ZSWIM8 zinc finger, SWIM-type containing 8
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1