VAMP2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description vesicle-associated membrane protein 2 (synaptobrevin 2)|The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6844)
External Link http://www.ncbi.nlm.nih.gov/gene/6844
Similar Terms
Downloads & Tools

Genes

370 interacting proteins for VAMP2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACAA2 acetyl-CoA acyltransferase 2
ACAD9 acyl-CoA dehydrogenase family, member 9
ACTB actin, beta
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
ADRB1 adrenoceptor beta 1
ALB albumin
ALDOA aldolase A, fructose-bisphosphate
ANGPT2 angiopoietin 2
ANKAR ankyrin and armadillo repeat containing
ANXA2 annexin A2
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
ASPH aspartate beta-hydroxylase
ATP13A2 ATPase type 13A2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
AVP arginine vasopressin
BAG6 BCL2-associated athanogene 6
BCAP31 B-cell receptor-associated protein 31
BOLA2 bolA family member 2
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
CAB39 calcium binding protein 39
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALB1 calbindin 1, 28kDa
CALCOCO2 calcium binding and coiled-coil domain 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALU calumenin
CATSPER1 cation channel, sperm associated 1
CATSPER2 cation channel, sperm associated 2
CATSPER3 cation channel, sperm associated 3
CATSPER4 cation channel, sperm associated 4
CATSPERB catsper channel auxiliary subunit beta
CATSPERD catsper channel auxiliary subunit delta
CATSPERG catsper channel auxiliary subunit gamma
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CEP290 centrosomal protein 290kDa
CHAT choline O-acetyltransferase
CHRM2 cholinergic receptor, muscarinic 2
CHRM4 cholinergic receptor, muscarinic 4
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CKB creatine kinase, brain
CKM creatine kinase, muscle
CKMT1A creatine kinase, mitochondrial 1A
CLIC2 chloride intracellular channel 2
CLINT1 clathrin interactor 1
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
CNGA1 cyclic nucleotide gated channel alpha 1
CNGB1 cyclic nucleotide gated channel beta 1
CNTNAP2 contactin associated protein-like 2
CPLX1 complexin 1
CPLX2 complexin 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCD dermcidin
DDAH1 dimethylarginine dimethylaminohydrolase 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM1 dynamin 1
DPYSL2 dihydropyrimidinase-like 2
DRD1 dopamine receptor D1
DRD5 dopamine receptor D5
DSG1 desmoglein 1
DSP desmoplakin
DTD1 D-tyrosyl-tRNA deacylase 1
DYNLL1 dynein, light chain, LC8-type 1
ECH1 enoyl CoA hydratase 1, peroxisomal
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EIF5A eukaryotic translation initiation factor 5A
EMD emerin
ENO3 enolase 3 (beta, muscle)
ERC2 ELKS/RAB6-interacting/CAST family member 2
EXOC1 exocyst complex component 1
EXOC4 exocyst complex component 4
FAR1 fatty acyl CoA reductase 1
FBXO2 F-box protein 2
FH fumarate hydratase
FKBP1B FK506 binding protein 1B, 12.6 kDa
FKBP2 FK506 binding protein 2, 13kDa
FLG2 filaggrin family member 2
FLNA filamin A, alpha
FLNC filamin C, gamma
FLOT1 flotillin 1
FLOT2 flotillin 2
FSCN1 fascin actin-bundling protein 1
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
FYCO1 FYVE and coiled-coil domain containing 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GAS8 growth arrest-specific 8
GDI1 GDP dissociation inhibitor 1
GDI2 GDP dissociation inhibitor 2
GEMIN2 gem (nuclear organelle) associated protein 2
GEMIN4 gem (nuclear organelle) associated protein 4
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GPC4 glypican 4
GRB10 growth factor receptor-bound protein 10
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GSTM1 glutathione S-transferase mu 1
GUK1 guanylate kinase 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HBA2 hemoglobin, alpha 2
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIRIP3 HIRA interacting protein 3
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPF heterogeneous nuclear ribonucleoprotein F
HRNR hornerin
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ILF3 interleukin enhancer binding factor 3, 90kDa
INS insulin
IQCB1 IQ motif containing B1
IQGAP3 IQ motif containing GTPase activating protein 3
ITGA11 integrin, alpha 11
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LDHAL6A lactate dehydrogenase A-like 6A
LOX lysyl oxidase
LPCAT2 lysophosphatidylcholine acyltransferase 2
LTN1 listerin E3 ubiquitin protein ligase 1
MAG myelin associated glycoprotein
MAP1B microtubule-associated protein 1B
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MCOLN1 mucolipin 1
MCOLN2 mucolipin 2
MCOLN3 mucolipin 3
MDH1 malate dehydrogenase 1, NAD (soluble)
MRPL16 mitochondrial ribosomal protein L16
MSR1 macrophage scavenger receptor 1
MYH9 myosin, heavy chain 9, non-muscle
MYO1C myosin IC
NAP1L1 nucleosome assembly protein 1-like 1
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta
NEFM neurofilament, medium polypeptide
NRF1 nuclear respiratory factor 1
NSF N-ethylmaleimide-sensitive factor
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
NUP188 nucleoporin 188kDa
ORAI1 ORAI calcium release-activated calcium modulator 1
OXCT1 3-oxoacid CoA transferase 1
OXTR oxytocin receptor
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCP4 Purkinje cell protein 4
PCP4L1 Purkinje cell protein 4 like 1
PDYN prodynorphin
PEA15 phosphoprotein enriched in astrocytes 15
PEBP1 phosphatidylethanolamine binding protein 1
PENK proenkephalin
PFDN2 prefoldin subunit 2
PGAM1 phosphoglycerate mutase 1 (brain)
PGD phosphogluconate dehydrogenase
PGK1 phosphoglycerate kinase 1
POMC proopiomelanocortin
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDX1 peroxiredoxin 1
PRDX5 peroxiredoxin 5
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKD3 protein kinase D3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKX protein kinase, X-linked
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PUM1 pumilio RNA-binding family member 1
QDPR quinoid dihydropteridine reductase
RAB14 RAB14, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB3C RAB3C, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RABAC1 Rab acceptor 1 (prenylated)
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RIMS1 regulating synaptic membrane exocytosis 1
RNH1 ribonuclease/angiogenin inhibitor 1
RPS12 ribosomal protein S12
RRBP1 ribosome binding protein 1
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
RYR3 ryanodine receptor 3
S100A16 S100 calcium binding protein A16
SCFD1 sec1 family domain containing 1
SDCBP syndecan binding protein (syntenin)
SEC16A SEC16 homolog A (S. cerevisiae)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEPT9 septin 9
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SF1 splicing factor 1
SFXN3 sideroflexin 3
SGPL1 sphingosine-1-phosphate lyase 1
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2
SH3D19 SH3 domain containing 19
SKP1 S-phase kinase-associated protein 1
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMN2 survival of motor neuron 2, centromeric
SNAP23 synaptosomal-associated protein, 23kDa
SNAP25 synaptosomal-associated protein, 25kDa
SPATA24 spermatogenesis associated 24
SQRDL sulfide quinone reductase-like (yeast)
SRI sorcin
STIM1 stromal interaction molecule 1
STX11 syntaxin 11
STX12 syntaxin 12
STX1A syntaxin 1A (brain)
STX1B syntaxin 1B
STX2 syntaxin 2
STX3 syntaxin 3
STX4 syntaxin 4
STX6 syntaxin 6
STX7 syntaxin 7
STX8 syntaxin 8
STXBP1 syntaxin binding protein 1
STXBP2 syntaxin binding protein 2
STXBP3 syntaxin binding protein 3
SVOPL SVOP-like
SYN1 synapsin I
SYN2 synapsin II
SYN3 synapsin III
SYP synaptophysin
SYPL1 synaptophysin-like 1
SYT1 synaptotagmin I
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TDP1 tyrosyl-DNA phosphodiesterase 1
THBS1 thrombospondin 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TPCN1 two pore segment channel 1
TPCN2 two pore segment channel 2
TPI1 triosephosphate isomerase 1
TRAP1 TNF receptor-associated protein 1
TRDN triadin
TRH thyrotropin-releasing hormone
TRIM21 tripartite motif containing 21
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA4A tubulin, alpha 4a
TUBA4B tubulin, alpha 4b
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
TUBB6 tubulin, beta 6 class V
TUBB8 tubulin, beta 8 class VIII
TWF2 twinfilin actin binding protein 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBAP2L ubiquitin associated protein 2-like
UBC ubiquitin C
UBE2K ubiquitin-conjugating enzyme E2K
UBE2M ubiquitin-conjugating enzyme E2M
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBE3B ubiquitin protein ligase E3B
UBXN1 UBX domain protein 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNC13B unc-13 homolog B (C. elegans)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAMP3 vesicle-associated membrane protein 3
VAMP7 vesicle-associated membrane protein 7
VAMP8 vesicle-associated membrane protein 8
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VTI1B vesicle transport through interaction with t-SNAREs 1B
XPOT exportin, tRNA
YBX1 Y box binding protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta