| Dataset | NURSA Protein-Protein Interactions |
| Category | proteomics |
| Type | interacting protein |
| Description | vasodilator-stimulated phosphoprotein|Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7408) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/7408 |
| Similar Terms | |
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3 interacting proteins for VASP from the NURSA Protein-Protein Interactions dataset.
