| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | valosin containing protein|The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7415) |
| External Link | https://ncbi.nlm.nih.gov/gene/7415 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the VCP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0245263 |
| ATF3 | activating transcription factor 3 | 0.0228923 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0208429 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0198896 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0196022 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0185279 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0181277 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0171391 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.0166959 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.0164829 |
| LTF | lactotransferrin | 0.0162515 |
| AREG | amphiregulin | 0.0160528 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0160253 |
| S100P | S100 calcium binding protein P | 0.015883 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.0156178 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0152073 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0147888 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0137487 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0137094 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0136392 |
| RCAN1 | regulator of calcineurin 1 | 0.0135395 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0133711 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.0133518 |
| TUFT1 | tuftelin 1 | 0.0130797 |
| MIR22HG | MIR22 host gene | 0.0130228 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0129417 |
| RRAGC | Ras-related GTP binding C | 0.012792 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0125198 |
| CTH | cystathionine gamma-lyase | 0.0123118 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0122748 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0122527 |
| STC2 | stanniocalcin 2 | 0.0119838 |
| SQSTM1 | sequestosome 1 | 0.0118499 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.0117942 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0117759 |
| PERP | PERP, TP53 apoptosis effector | 0.0116864 |
| PITX3 | paired-like homeodomain 3 | 0.0116136 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0115799 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0114798 |
| RIT1 | Ras-like without CAAX 1 | 0.0113984 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0112922 |
| BTG2 | BTG family, member 2 | 0.0112865 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0112659 |
| APOD | apolipoprotein D | 0.0112166 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.0111794 |
| PROM1 | prominin 1 | 0.0111725 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0111693 |
| ABHD4 | abhydrolase domain containing 4 | 0.0111412 |
| AKIRIN1 | akirin 1 | 0.011107 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0111001 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0110516 |
| KLF6 | Kruppel-like factor 6 | 0.0110044 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0108988 |
| OXSR1 | oxidative stress responsive 1 | 0.0108047 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.0106924 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.0106583 |
| G0S2 | G0/G1 switch 2 | 0.0106241 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0104781 |
| XIC | X chromosome inactivation center | 0.0104721 |
| XBP1 | X-box binding protein 1 | 0.0104632 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.0104444 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0104432 |
| HEBP2 | heme binding protein 2 | 0.0104345 |
| DUSP14 | dual specificity phosphatase 14 | 0.0103991 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0103672 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0102922 |
| GLRX | glutaredoxin (thioltransferase) | 0.0102651 |
| DSP | desmoplakin | 0.01025 |
| LARP6 | La ribonucleoprotein domain family, member 6 | 0.010245 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0102325 |
| MYO6 | myosin VI | 0.0101657 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0100079 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00998647 |
| RIOK3 | RIO kinase 3 | 0.00996267 |
| CRY1 | cryptochrome circadian clock 1 | 0.00994525 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00992158 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00988664 |
| NPC1 | Niemann-Pick disease, type C1 | 0.00987621 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00986325 |
| EGR1 | early growth response 1 | 0.00979729 |
| IL6ST | interleukin 6 signal transducer | 0.00970217 |
| KRT14 | keratin 14, type I | 0.00969869 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.0096978 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0096592 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00952362 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00949597 |
| NUCB2 | nucleobindin 2 | 0.0094188 |
| CRYAB | crystallin, alpha B | 0.00938486 |
| CORO1C | coronin, actin binding protein, 1C | 0.0093842 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.00937394 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00936087 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00912886 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00912597 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0090904 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0090244 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.0090108 |
| IER3 | immediate early response 3 | 0.0089989 |
| INSL3 | insulin-like 3 (Leydig cell) | 0.00898833 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00898519 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00893136 |
| FOSL2 | FOS-like antigen 2 | 0.00890912 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00890545 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00889936 |
| GAB2 | GRB2-associated binding protein 2 | 0.00879914 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00876396 |
| BLVRB | biliverdin reductase B | 0.00874849 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.00870066 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00861332 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00861011 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase | 0.00859753 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.00859412 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00859121 |
| TRIB3 | tribbles pseudokinase 3 | 0.00858162 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00853893 |
| KLHL24 | kelch-like family member 24 | 0.00852671 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0085245 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00852304 |
| KLK5 | kallikrein-related peptidase 5 | 0.00850917 |
| FOXD1 | forkhead box D1 | 0.00850281 |
| JMJD1C | jumonji domain containing 1C | 0.0084947 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00844477 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.00843702 |
| TAF9 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 0.00840148 |
| JMJD6 | jumonji domain containing 6 | 0.00839469 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00839402 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.00839221 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00836702 |
| BLNK | B-cell linker | 0.00836672 |
| ARG2 | arginase 2 | 0.00835723 |
| OGA | O-GlcNAcase | 0.00835512 |
| INHBA | inhibin, beta A | 0.00834616 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00829339 |
| SEC61B | Sec61 beta subunit | 0.00829287 |
| IER5 | immediate early response 5 | 0.0082001 |
| CLTB | clathrin, light chain B | 0.00819758 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.00818689 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00818273 |
| ATF4 | activating transcription factor 4 | 0.0081807 |
| TXNRD1 | thioredoxin reductase 1 | 0.00817841 |
| VNN1 | vanin 1 | 0.00817023 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00816003 |
| GOLT1B | golgi transport 1B | 0.0081523 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00813419 |
| IL6R | interleukin 6 receptor | 0.00812862 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00812256 |
| IL1A | interleukin 1, alpha | 0.00806738 |
| NDRG1 | N-myc downstream regulated 1 | 0.00803426 |
| DUSP5 | dual specificity phosphatase 5 | 0.00801864 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00800363 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.00799965 |
| BEX4 | brain expressed, X-linked 4 | 0.00798882 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.00798312 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00795159 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00791468 |
| PRNP | prion protein | 0.00791424 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.00789278 |
| FBN2 | fibrillin 2 | 0.00787281 |
| SPAG9 | sperm associated antigen 9 | 0.00787057 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00786385 |
| MSX1 | msh homeobox 1 | 0.00785532 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.00785244 |
| PXDC1 | PX domain containing 1 | 0.00783927 |
| ZNF91 | zinc finger protein 91 | 0.00782586 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | 0.00780845 |
| HECA | headcase homolog (Drosophila) | 0.00779972 |
| LIN37 | lin-37 DREAM MuvB core complex component | 0.00777264 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.00776866 |
| REG1A | regenerating islet-derived 1 alpha | 0.00776559 |
| KRT19 | keratin 19, type I | 0.00773057 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00772831 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 0.00770422 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.00769471 |
| TFG | TRK-fused gene | 0.00767765 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.00765589 |
| RAB5A | RAB5A, member RAS oncogene family | 0.00765385 |
| S100A11 | S100 calcium binding protein A11 | 0.00764459 |
| SLC38A1 | solute carrier family 38, member 1 | 0.007552 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00754948 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00754883 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00754156 |
| THBS1 | thrombospondin 1 | 0.00751715 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.00751575 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00748263 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.00747143 |
| SERINC1 | serine incorporator 1 | 0.00746796 |
| WTAP | Wilms tumor 1 associated protein | 0.00746477 |
| DSTN | destrin (actin depolymerizing factor) | 0.00744824 |
| INSM1 | insulinoma-associated 1 | 0.00743153 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.00743 |
| PLK3 | polo-like kinase 3 | 0.00742309 |
| USP47 | ubiquitin specific peptidase 47 | 0.00742081 |
| ELOB | elongin B | 0.00739518 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00737949 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.00735433 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) | 0.00735073 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00728079 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00727849 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00726603 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.00723295 |
| SH3BGR | SH3 domain binding glutamate-rich protein | 0.00717554 |
| IFT20 | intraflagellar transport 20 | 0.00715372 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.00715362 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00715138 |
| RAB8B | RAB8B, member RAS oncogene family | 0.00714723 |
| CREM | cAMP responsive element modulator | 0.00714372 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00714062 |
| RNF103 | ring finger protein 103 | 0.00713232 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.00712644 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.00711698 |
| HCFC2 | host cell factor C2 | 0.00710708 |
| PTHLH | parathyroid hormone-like hormone | 0.00706844 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00705228 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | 0.00704373 |
| ADM | adrenomedullin | 0.00704093 |
| SMAD3 | SMAD family member 3 | 0.00702875 |
| RGS2 | regulator of G-protein signaling 2 | 0.00702588 |
| FOSL1 | FOS-like antigen 1 | 0.00702195 |
| NUP58 | nucleoporin 58 | 0.00699536 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00699292 |
| ZNF165 | zinc finger protein 165 | 0.00696127 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00695769 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00694794 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00692819 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.006919 |
| UPP1 | uridine phosphorylase 1 | 0.00691416 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00688208 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00687928 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0068742 |
| CCND2 | cyclin D2 | 0.00685277 |
| FHL2 | four and a half LIM domains 2 | 0.00682949 |
| KRT5 | keratin 5, type II | 0.00682482 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00681655 |
| BTG3 | BTG family, member 3 | 0.00680825 |
| SEC61G | Sec61 gamma subunit | 0.00680611 |
| MGST3 | microsomal glutathione S-transferase 3 | 0.00680414 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0068038 |
| GTF2B | general transcription factor IIB | 0.0067919 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.00676211 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.0067621 |
| TFF1 | trefoil factor 1 | 0.00675894 |
| FERMT2 | fermitin family member 2 | 0.00671097 |
| RNF11 | ring finger protein 11 | 0.00670775 |
| IL33R | interleukin 33 receptor | 0.00670443 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00670391 |
| SUCO | SUN domain containing ossification factor | 0.00669086 |
| HBP1 | HMG-box transcription factor 1 | 0.00668998 |
| ZNF394 | zinc finger protein 394 | 0.00666688 |
| PRPF18 | pre-mRNA processing factor 18 | 0.00666232 |
| EGFR | epidermal growth factor receptor | 0.00664773 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 | 0.00664246 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF20A | kinesin family member 20A | -0.014062 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0129136 |
| TRIB2 | tribbles pseudokinase 2 | -0.0128905 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.0128556 |
| CCNA2 | cyclin A2 | -0.012803 |
| CCNF | cyclin F | -0.0127644 |
| TRIM14 | tripartite motif containing 14 | -0.0126998 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.0122993 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0121701 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0121559 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0120228 |
| SORD | sorbitol dehydrogenase | -0.0119825 |
| KIF18B | kinesin family member 18B | -0.0116893 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.0115329 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0114307 |
| TNC | tenascin C | -0.0113932 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.0113858 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0113572 |
| MAGEA3 | melanoma antigen family A3 | -0.0112912 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0111979 |
| LMNB1 | lamin B1 | -0.0111801 |
| CD320 | CD320 molecule | -0.0111085 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.0110854 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.0110257 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0109783 |
| PLK1 | polo-like kinase 1 | -0.0109396 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.0109201 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0109169 |
| CDC7 | cell division cycle 7 | -0.0108925 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.0107816 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0106814 |
| BGN | biglycan | -0.0106789 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0104917 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | -0.0104003 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0103859 |
| CENPF | centromere protein F, 350/400kDa | -0.0102702 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0102502 |
| NEK2 | NIMA-related kinase 2 | -0.0101954 |
| PBK | PDZ binding kinase | -0.0100341 |
| CCNB2 | cyclin B2 | -0.0100096 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.00999419 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -0.00988531 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00986838 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00976889 |
| KIF11 | kinesin family member 11 | -0.00969163 |
| OIP5 | Opa interacting protein 5 | -0.00968789 |
| SLC35E2B | solute carrier family 35, member E2B | -0.00965154 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00962692 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00952534 |
| JADE2 | jade family PHD finger 2 | -0.00944838 |
| KIF15 | kinesin family member 15 | -0.00941168 |
| GAS1 | growth arrest-specific 1 | -0.00939705 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00939302 |
| CDK1 | cyclin-dependent kinase 1 | -0.00933982 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00932574 |
| CEP55 | centrosomal protein 55kDa | -0.00932336 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.00929637 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00921322 |
| ANOS1 | anosmin 1 | -0.00919484 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.00917205 |
| KIF4A | kinesin family member 4A | -0.00915244 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00912428 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00904136 |
| UNG | uracil-DNA glycosylase | -0.00903075 |
| NDC80 | NDC80 kinetochore complex component | -0.00889468 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00889287 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.00884591 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00883432 |
| CBR4 | carbonyl reductase 4 | -0.00883026 |
| MARCKSL1 | MARCKS-like 1 | -0.00874336 |
| MCM3 | minichromosome maintenance complex component 3 | -0.00873576 |
| MUC16 | mucin 16, cell surface associated | -0.0086922 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00868887 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.00866918 |
| ZMYM3 | zinc finger, MYM-type 3 | -0.00863283 |
| RBM8A | RNA binding motif protein 8A | -0.00863109 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00859181 |
| CHEK2 | checkpoint kinase 2 | -0.00857522 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00855381 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00855237 |
| FANCG | Fanconi anemia, complementation group G | -0.0085478 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | -0.00853723 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00850006 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00849587 |
| C7 | complement component 7 | -0.00847829 |
| PCYOX1L | prenylcysteine oxidase 1 like | -0.00845673 |
| NCAPH | non-SMC condensin I complex, subunit H | -0.00842122 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00841922 |
| TSPAN4 | tetraspanin 4 | -0.00841131 |
| DUT | deoxyuridine triphosphatase | -0.00840961 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | -0.00840563 |
| MAGEA12 | melanoma antigen family A12 | -0.00840207 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00838333 |
| APOL1 | apolipoprotein L, 1 | -0.0083779 |
| TPX2 | TPX2, microtubule-associated | -0.00837172 |
| COL4A1 | collagen, type IV, alpha 1 | -0.00835446 |
| AURKA | aurora kinase A | -0.00833566 |
| FOXM1 | forkhead box M1 | -0.00833457 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | -0.00830574 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00829611 |
| CBX3 | chromobox homolog 3 | -0.00828934 |
| TMCO6 | transmembrane and coiled-coil domains 6 | -0.00827125 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00826369 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00824423 |
| KIF14 | kinesin family member 14 | -0.00824354 |
| COL3A1 | collagen, type III, alpha 1 | -0.00819023 |
| LY75 | lymphocyte antigen 75 | -0.00818744 |
| TAPBP | TAP binding protein (tapasin) | -0.00816814 |
| GGCT | gamma-glutamylcyclotransferase | -0.00815335 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -0.00813252 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00809091 |
| METTL7A | methyltransferase like 7A | -0.00804333 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00801821 |
| PRDX2 | peroxiredoxin 2 | -0.00799582 |
| CDCA3 | cell division cycle associated 3 | -0.00799213 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | -0.00793228 |
| ERI2 | ERI1 exoribonuclease family member 2 | -0.00790974 |
| HYAL2 | hyaluronoglucosaminidase 2 | -0.00787603 |
| HMGB3 | high mobility group box 3 | -0.00787509 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.00786134 |
| NDRG3 | NDRG family member 3 | -0.00786022 |
| DNA2 | DNA replication helicase/nuclease 2 | -0.00785444 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00784395 |
| LMNB2 | lamin B2 | -0.00782961 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.0078227 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.00781723 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00780287 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0077804 |
| TGM2 | transglutaminase 2 | -0.00777247 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00776512 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00776412 |
| TIMELESS | timeless circadian clock | -0.00775879 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00775098 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00771858 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | -0.00771241 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | -0.00771137 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00771 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | -0.00770678 |
| TNS3 | tensin 3 | -0.00769448 |
| CHN1 | chimerin 1 | -0.00762141 |
| TRMT5 | tRNA methyltransferase 5 | -0.00761762 |
| RPIA | ribose 5-phosphate isomerase A | -0.00761354 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00759395 |
| MYO1C | myosin IC | -0.00758158 |
| COL15A1 | collagen, type XV, alpha 1 | -0.007572 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00757133 |
| COL1A2 | collagen, type I, alpha 2 | -0.00756033 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F | -0.00753419 |
| ZWINT | ZW10 interacting kinetochore protein | -0.00751851 |
| MCM5 | minichromosome maintenance complex component 5 | -0.00751269 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00750755 |
| DHFR | dihydrofolate reductase | -0.00750413 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.00750406 |
| CDC20 | cell division cycle 20 | -0.00748791 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | -0.00748208 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00741951 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | -0.00740059 |
| FANCI | Fanconi anemia, complementation group I | -0.00739308 |
| TK1 | thymidine kinase 1, soluble | -0.00737574 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00737059 |
| THYN1 | thymocyte nuclear protein 1 | -0.00736422 |
| CKAP2 | cytoskeleton associated protein 2 | -0.00735877 |
| SLC38A10 | solute carrier family 38, member 10 | -0.00732453 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00725223 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -0.00724961 |
| DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) | -0.00724748 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | -0.00721736 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00720457 |
| TMEM97 | transmembrane protein 97 | -0.00720446 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.0071958 |
| E2F8 | E2F transcription factor 8 | -0.0071954 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00719475 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00719234 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00718676 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00718486 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.0071803 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00715607 |
| KIF23 | kinesin family member 23 | -0.00714065 |
| TROAP | trophinin associated protein | -0.00713337 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00711386 |
| CDCA4 | cell division cycle associated 4 | -0.00710921 |
| RANBP1 | RAN binding protein 1 | -0.00710881 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 | -0.00710331 |
| XPO1 | exportin 1 | -0.0070954 |
| CENPE | centromere protein E, 312kDa | -0.00709194 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00708624 |
| CTSK | cathepsin K | -0.00707464 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | -0.00706467 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00706202 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | -0.007062 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00704942 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.0070227 |
| RMI1 | RecQ mediated genome instability 1 | -0.00701541 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00701087 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.0070078 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00700739 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00700366 |
| ANGEL2 | angel homolog 2 (Drosophila) | -0.00700278 |
| CDC25B | cell division cycle 25B | -0.00699817 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00699267 |
| COMT | catechol-O-methyltransferase | -0.00698452 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00691439 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.00689561 |
| RNF167 | ring finger protein 167 | -0.00687237 |
| OLFM1 | olfactomedin 1 | -0.00687163 |
| THEM6 | thioesterase superfamily member 6 | -0.00686922 |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase | -0.00686499 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -0.00685796 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 | -0.00684107 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00681065 |
| TMEM14A | transmembrane protein 14A | -0.00679035 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.00676771 |
| S100A8 | S100 calcium binding protein A8 | -0.0067613 |
| NUDCD3 | NudC domain containing 3 | -0.00676109 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.0067429 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -0.00673295 |
| CTSC | cathepsin C | -0.00672711 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00672508 |
| CFB | complement factor B | -0.00671767 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | -0.00670892 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0066921 |
| AGRN | agrin | -0.00665878 |
| GLB1 | galactosidase, beta 1 | -0.0066582 |
| GAA | glucosidase, alpha; acid | -0.00664827 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0066418 |
| IFI44L | interferon-induced protein 44-like | -0.00664031 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.0066272 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00662159 |
| KIFC1 | kinesin family member C1 | -0.00661882 |
| MELK | maternal embryonic leucine zipper kinase | -0.00661757 |
| FASN | fatty acid synthase | -0.00661554 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00660769 |
| NUP37 | nucleoporin 37kDa | -0.00659975 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -0.00659301 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | -0.0065906 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | -0.00658605 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00658469 |
| PODXL | podocalyxin-like | -0.00658313 |
| EPHB2 | EPH receptor B2 | -0.0065741 |
| CFI | complement factor I | -0.00657399 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.00657211 |
| MCM4 | minichromosome maintenance complex component 4 | -0.00656361 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00655417 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -0.00654569 |
| PRKD3 | protein kinase D3 | -0.00654312 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.00654304 |
| GANAB | glucosidase, alpha; neutral AB | -0.00652693 |
| ERLIN2 | ER lipid raft associated 2 | -0.00652186 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00650549 |
