| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | vascular endothelial growth factor A|This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7422) |
| External Link | https://ncbi.nlm.nih.gov/gene/7422 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the VEGFA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.01641 |
| PRAME | preferentially expressed antigen in melanoma | 0.0153723 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0125854 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.0111866 |
| MMP9 | matrix metallopeptidase 9 | 0.0104966 |
| IQCG | IQ motif containing G | 0.010432 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.0103201 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0101237 |
| RCAN1 | regulator of calcineurin 1 | 0.0100131 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00982731 |
| XIC | X chromosome inactivation center | 0.00963974 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00962214 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00958344 |
| ADD3 | adducin 3 (gamma) | 0.00943861 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00920606 |
| CA12 | carbonic anhydrase XII | 0.00919194 |
| RHOB | ras homolog family member B | 0.00893114 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00880412 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00879906 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00876311 |
| FCGBP | Fc fragment of IgG binding protein | 0.0086319 |
| OLFM4 | olfactomedin 4 | 0.00855408 |
| TSPYL5 | TSPY-like 5 | 0.00850599 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00838251 |
| KRT15 | keratin 15, type I | 0.00838108 |
| NID2 | nidogen 2 (osteonidogen) | 0.00836039 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00826884 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00822014 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.0081774 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0081227 |
| MSX1 | msh homeobox 1 | 0.00808737 |
| ANXA3 | annexin A3 | 0.0080453 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00803575 |
| CHI3L2 | chitinase 3-like 2 | 0.00794862 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.0079258 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00788655 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00785715 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.00784834 |
| PROM1 | prominin 1 | 0.00784123 |
| IL2RG | interleukin 2 receptor, gamma | 0.00783127 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00777179 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00769314 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00768068 |
| STC1 | stanniocalcin 1 | 0.00762599 |
| GALC | galactosylceramidase | 0.0075989 |
| MMD | monocyte to macrophage differentiation-associated | 0.00757982 |
| MICB | MHC class I polypeptide-related sequence B | 0.00757122 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00752035 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00749656 |
| PITX3 | paired-like homeodomain 3 | 0.0074661 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00745563 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00741632 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00741257 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00739088 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00737718 |
| ARG1 | arginase 1 | 0.00734574 |
| MGAM | maltase-glucoamylase | 0.00727404 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00726392 |
| MAOB | monoamine oxidase B | 0.00725389 |
| FBXO21 | F-box protein 21 | 0.00724443 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00724338 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 0.00716808 |
| SHTN1 | shootin 1 | 0.00714718 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00709107 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00708779 |
| CENPE | centromere protein E, 312kDa | 0.00707612 |
| KIAA0226L | KIAA0226-like | 0.00702079 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00698872 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.0069652 |
| MICA | MHC class I polypeptide-related sequence A | 0.00695173 |
| WT1 | Wilms tumor 1 | 0.00695118 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00694407 |
| S100A10 | S100 calcium binding protein A10 | 0.00694403 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00691272 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00690838 |
| PNMA8A | PNMA family member 8A | 0.00689996 |
| HLTF | helicase-like transcription factor | 0.00689111 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00688559 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0068746 |
| LCN2 | lipocalin 2 | 0.0068521 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00684302 |
| ATP10D | ATPase, class V, type 10D | 0.00682731 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00681301 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00679008 |
| CSTA | cystatin A (stefin A) | 0.00678065 |
| VAMP7 | vesicle-associated membrane protein 7 | 0.00677348 |
| CFI | complement factor I | 0.00676386 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00675176 |
| PBK | PDZ binding kinase | 0.00671755 |
| KRT5 | keratin 5, type II | 0.00667423 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00665566 |
| CHN1 | chimerin 1 | 0.00663285 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00662071 |
| GMPR | guanosine monophosphate reductase | 0.00661656 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.00659508 |
| STC2 | stanniocalcin 2 | 0.00657031 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00656789 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00652279 |
| XK | X-linked Kx blood group | 0.00651757 |
| CALML5 | calmodulin-like 5 | 0.00651004 |
| ACP3 | acid phosphatase 3 | 0.00650685 |
| CFB | complement factor B | 0.00650343 |
| SVIL | supervillin | 0.00650273 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00650269 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00650047 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00649699 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.006476 |
| CHPT1 | choline phosphotransferase 1 | 0.00646517 |
| LOR | loricrin | 0.00643778 |
| SELL | selectin L | 0.00640719 |
| EFHD1 | EF-hand domain family, member D1 | 0.00639546 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00639532 |
| ZNF354A | zinc finger protein 354A | 0.00639501 |
| MT1X | metallothionein 1X | 0.00638401 |
| FMR1 | fragile X mental retardation 1 | 0.00638345 |
| COCH | cochlin | 0.00638295 |
| DAXX | death-domain associated protein | 0.00637783 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00636524 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00635441 |
| SELENBP1 | selenium binding protein 1 | 0.00635153 |
| FYB1 | FYN binding protein 1 | 0.00634171 |
| SIRT3 | sirtuin 3 | 0.00631963 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00629935 |
| DEFB1 | defensin, beta 1 | 0.00629545 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00625921 |
| OSBPL11 | oxysterol binding protein-like 11 | 0.00623306 |
| CANX | calnexin | 0.00622218 |
| MMP8 | matrix metallopeptidase 8 | 0.00621696 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00620024 |
| SERINC5 | serine incorporator 5 | 0.00618736 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00618326 |
| KRT81 | keratin 81, type II | 0.00617508 |
| TKTL1 | transketolase-like 1 | 0.0061745 |
| FZD7 | frizzled class receptor 7 | 0.00616359 |
| LY75 | lymphocyte antigen 75 | 0.00615599 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00615369 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00614069 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00613627 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00613462 |
| MX1 | MX dynamin-like GTPase 1 | 0.00613013 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00612978 |
| S100A7 | S100 calcium binding protein A7 | 0.0061096 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00610557 |
| SRGN | serglycin | 0.00607825 |
| C5ORF30 | chromosome 5 open reading frame 30 | 0.00607489 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00606728 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00605705 |
| ADI1 | acireductone dioxygenase 1 | 0.00605222 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00604957 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00600489 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00600338 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00599818 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.00598708 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.00598317 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | 0.00597974 |
| CNN3 | calponin 3, acidic | 0.00596774 |
| SYCP2 | synaptonemal complex protein 2 | 0.0059575 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00595324 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.00595075 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00594585 |
| EDN3 | endothelin 3 | 0.0059018 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00589588 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.00588976 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00588658 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00586783 |
| TBX3 | T-box 3 | 0.0058533 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | 0.00583109 |
| TLE4 | transducin-like enhancer of split 4 | 0.00582288 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 0.00580311 |
| PRKCA | protein kinase C, alpha | 0.00580093 |
| COL15A1 | collagen, type XV, alpha 1 | 0.0057484 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.0057154 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00571025 |
| DNM1L | dynamin 1-like | 0.00570948 |
| HOXD1 | homeobox D1 | 0.00570798 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00569477 |
| RRM2 | ribonucleotide reductase M2 | 0.00567453 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00565504 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | 0.00565444 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00565263 |
| POU4F1 | POU class 4 homeobox 1 | 0.00564081 |
| KRT1 | keratin 1, type II | 0.00563508 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.00561088 |
| KLK3 | kallikrein-related peptidase 3 | 0.0056082 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00560009 |
| DSG1 | desmoglein 1 | 0.00558764 |
| GOLGA8A | golgin A8 family, member A | 0.00556149 |
| PRR7 | proline rich 7 (synaptic) | 0.00555618 |
| CDC42 | cell division cycle 42 | 0.00555585 |
| RESF1 | retroelement silencing factor 1 | 0.00555375 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.00554612 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00554373 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00553959 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00553944 |
| ENAH | enabled homolog (Drosophila) | 0.0055336 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | 0.00552908 |
| MLF1 | myeloid leukemia factor 1 | 0.00552273 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00552056 |
| RGS10 | regulator of G-protein signaling 10 | 0.0055126 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.00549641 |
| CHKB | choline kinase beta | 0.00549293 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00547371 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00546991 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00546559 |
| MYO1C | myosin IC | 0.00545121 |
| SORD | sorbitol dehydrogenase | 0.00540967 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00540649 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.00540604 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0054032 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0054026 |
| ATG14 | autophagy related 14 | 0.0053957 |
| GOLM1 | golgi membrane protein 1 | 0.00539387 |
| HK2 | hexokinase 2 | 0.00538069 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.0053733 |
| TRIB2 | tribbles pseudokinase 2 | 0.0053596 |
| ZNF239 | zinc finger protein 239 | 0.00535407 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.00533072 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00531685 |
| OAT | ornithine aminotransferase | 0.00531159 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00529038 |
| FGF13 | fibroblast growth factor 13 | 0.00527757 |
| KIF5C | kinesin family member 5C | 0.00526 |
| MTM1 | myotubularin 1 | 0.00525337 |
| ZNF107 | zinc finger protein 107 | 0.00523416 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00521827 |
| GRAMD2B | GRAM domain containing 2B | 0.00520726 |
| TMEM255A | transmembrane protein 255A | 0.00519615 |
| CLCA1 | chloride channel accessory 1 | 0.0051774 |
| ZNF43 | zinc finger protein 43 | 0.0051772 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00517656 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.00517029 |
| DCP2 | decapping mRNA 2 | 0.00516611 |
| CLINT1 | clathrin interactor 1 | 0.00516556 |
| H1-2 | H1.2 linker histone, cluster member | 0.00516319 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00515121 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00513706 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | 0.00513602 |
| PRKCI | protein kinase C, iota | 0.00512252 |
| BPI | bactericidal/permeability-increasing protein | 0.00512222 |
| TMEM231 | transmembrane protein 231 | 0.00511687 |
| NFIB | nuclear factor I/B | 0.00511141 |
| AFP | alpha-fetoprotein | 0.00511118 |
| LYRM1 | LYR motif containing 1 | 0.0051039 |
| ELANE | elastase, neutrophil expressed | 0.00509725 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.00509456 |
| IL6ST | interleukin 6 signal transducer | 0.0050924 |
| FAM189A2 | family with sequence similarity 189, member A2 | 0.0050905 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00508635 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00507538 |
| POSTN | periostin, osteoblast specific factor | 0.00505233 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HOPX | HOP homeobox | -0.0137212 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0130619 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0117847 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0115499 |
| TNNC1 | troponin C type 1 (slow) | -0.0111313 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.0107742 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0106495 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0103791 |
| ZNF589 | zinc finger protein 589 | -0.0101431 |
| PCNA | proliferating cell nuclear antigen | -0.00995829 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00978278 |
| GPX3 | glutathione peroxidase 3 | -0.00978176 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00918294 |
| CCNB1 | cyclin B1 | -0.00912554 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | -0.00911795 |
| PRDX4 | peroxiredoxin 4 | -0.00910826 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00885436 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00871 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00869094 |
| TUBA4A | tubulin, alpha 4a | -0.00862541 |
| TAGLN | transgelin | -0.00857166 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -0.00854336 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.00849349 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00837345 |
| CHGB | chromogranin B | -0.00832382 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00831233 |
| LMNA | lamin A/C | -0.00828991 |
| AHR | aryl hydrocarbon receptor | -0.00825926 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00822966 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00817869 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00808931 |
| CES1 | carboxylesterase 1 | -0.00808033 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | -0.00804047 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00803523 |
| MGLL | monoglyceride lipase | -0.00803279 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00783528 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00779388 |
| CD14 | CD14 molecule | -0.00778731 |
| NRCAM | neuronal cell adhesion molecule | -0.00778522 |
| COMT | catechol-O-methyltransferase | -0.00778506 |
| CKM | creatine kinase, muscle | -0.00778282 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00775601 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00774386 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00770467 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00767142 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -0.00758237 |
| TOX3 | TOX high mobility group box family member 3 | -0.00757454 |
| PPL | periplakin | -0.00749456 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00749066 |
| INSM1 | insulinoma-associated 1 | -0.00745688 |
| KLHDC3 | kelch domain containing 3 | -0.00741299 |
| ZNF160 | zinc finger protein 160 | -0.00739702 |
| AGR2 | anterior gradient 2 | -0.00729809 |
| PLD3 | phospholipase D family, member 3 | -0.00727971 |
| TMEM176B | transmembrane protein 176B | -0.00727953 |
| PLXNB2 | plexin B2 | -0.00727881 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00725561 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00723878 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00721212 |
| IER5 | immediate early response 5 | -0.00720465 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00716498 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00713735 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00712939 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | -0.00706817 |
| TNS3 | tensin 3 | -0.00700251 |
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | -0.00695426 |
| ASPN | asporin | -0.00694066 |
| PGC | progastricsin (pepsinogen C) | -0.00693052 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -0.0068923 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00687027 |
| ABHD4 | abhydrolase domain containing 4 | -0.00684574 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0068353 |
| AMH | anti-Mullerian hormone | -0.00683184 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00681431 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0068064 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00679128 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00678852 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00678662 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.00676866 |
| C7 | complement component 7 | -0.0067487 |
| CSK | c-src tyrosine kinase | -0.00674867 |
| SFTPA2 | surfactant protein A2 | -0.00670228 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00668182 |
| CTSD | cathepsin D | -0.00668076 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00667749 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00667009 |
| ECM1 | extracellular matrix protein 1 | -0.00666802 |
| ADAMTSL3 | ADAMTS-like 3 | -0.0066573 |
| CD52 | CD52 molecule | -0.0066317 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00659466 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00659249 |
| DACH1 | dachshund family transcription factor 1 | -0.00656693 |
| SFN | stratifin | -0.00655826 |
| TTN | titin | -0.00654573 |
| PLN | phospholamban | -0.00654255 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00653554 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -0.00652931 |
| ILK | integrin-linked kinase | -0.00648818 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00646823 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -0.00646619 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00645192 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00643241 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00642774 |
| PRR11 | proline rich 11 | -0.00641653 |
| VASP | vasodilator-stimulated phosphoprotein | -0.00639283 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0063406 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00625437 |
| SFTPC | surfactant protein C | -0.00625066 |
| MCM5 | minichromosome maintenance complex component 5 | -0.0062483 |
| AOX1 | aldehyde oxidase 1 | -0.00622671 |
| KIAA0930 | KIAA0930 | -0.006225 |
| CLIC5 | chloride intracellular channel 5 | -0.00621732 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00618929 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.0061889 |
| MYOT | myotilin | -0.00618307 |
| CAVIN1 | caveolae associated protein 1 | -0.00617902 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | -0.00616386 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00616275 |
| CFH | complement factor H | -0.00613681 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.00612503 |
| MCM7 | minichromosome maintenance complex component 7 | -0.00610149 |
| KRT7 | keratin 7, type II | -0.00609388 |
| CDO1 | cysteine dioxygenase type 1 | -0.00608896 |
| KLHL41 | kelch-like family member 41 | -0.00608532 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00607408 |
| TGFB1 | transforming growth factor, beta 1 | -0.00604129 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00604107 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.00603498 |
| GPX4 | glutathione peroxidase 4 | -0.00602715 |
| FANCL | Fanconi anemia, complementation group L | -0.00602317 |
| MMP2 | matrix metallopeptidase 2 | -0.00601498 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00601214 |
| GPX2 | glutathione peroxidase 2 | -0.00598936 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00598516 |
| TSPO | translocator protein (18kDa) | -0.00597466 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00597397 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00597381 |
| ABHD2 | abhydrolase domain containing 2 | -0.00596232 |
| ZNF611 | zinc finger protein 611 | -0.00595211 |
| HOXB2 | homeobox B2 | -0.00592101 |
| MLPH | melanophilin | -0.00591001 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.00590269 |
| NPR3 | natriuretic peptide receptor 3 | -0.00587813 |
| ELN | elastin | -0.00586452 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00586414 |
| S100A2 | S100 calcium binding protein A2 | -0.00584169 |
| CERT1 | ceramide transporter 1 | -0.00584163 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0058415 |
| STK25 | serine/threonine kinase 25 | -0.00584086 |
| COQ8A | coenzyme Q8A | -0.00583793 |
| CYC1 | cytochrome c-1 | -0.00582882 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00582076 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | -0.005815 |
| MARCO | macrophage receptor with collagenous structure | -0.00579773 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.00577237 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | -0.00576713 |
| RHOD | ras homolog family member D | -0.00575259 |
| CCND2 | cyclin D2 | -0.00573925 |
| CD163 | CD163 molecule | -0.00573163 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00571525 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0056914 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00568699 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.00568409 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00567715 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.00565434 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00564043 |
| DCPS | decapping enzyme, scavenger | -0.00563576 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00563418 |
| SH2B2 | SH2B adaptor protein 2 | -0.00562085 |
| NELFB | negative elongation factor complex member B | -0.00560552 |
| MEF2C | myocyte enhancer factor 2C | -0.00560039 |
| NNMT | nicotinamide N-methyltransferase | -0.00558931 |
| CALB1 | calbindin 1, 28kDa | -0.00555768 |
| TNNC2 | troponin C type 2 (fast) | -0.0055575 |
| FHL1 | four and a half LIM domains 1 | -0.00555191 |
| RCAN2 | regulator of calcineurin 2 | -0.00552964 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00550543 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00549719 |
| FKBP2 | FK506 binding protein 2, 13kDa | -0.00548491 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00547322 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00546622 |
| H2AX | H2A.X variant histone | -0.00546409 |
| ADAP1 | ArfGAP with dual PH domains 1 | -0.00545317 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -0.00542706 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00542607 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00542068 |
| FASTK | Fas-activated serine/threonine kinase | -0.00539952 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00539204 |
| CBX6 | chromobox homolog 6 | -0.0053857 |
| SDHAP1 | succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 | -0.00537954 |
| SERF2 | small EDRK-rich factor 2 | -0.00537035 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | -0.00536875 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00536336 |
| C4BPA | complement component 4 binding protein, alpha | -0.00535607 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | -0.00535549 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00535244 |
| ACKR3 | atypical chemokine receptor 3 | -0.00534323 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00534205 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00533939 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00533861 |
| DES | desmin | -0.00531911 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.00530448 |
| SMAD7 | SMAD family member 7 | -0.00528249 |
| MRPL11 | mitochondrial ribosomal protein L11 | -0.00528101 |
| TMEM47 | transmembrane protein 47 | -0.00527238 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00526999 |
| CPB2 | carboxypeptidase B2 (plasma) | -0.00526795 |
| EPS8L2 | EPS8-like 2 | -0.00526243 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.00525539 |
| CHRDL1 | chordin-like 1 | -0.00525304 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.0052479 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00522738 |
| SSH3 | slingshot protein phosphatase 3 | -0.00521571 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00520597 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | -0.00520377 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00519836 |
| CENPB | centromere protein B, 80kDa | -0.00519409 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00519328 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.00519 |
| NARF | nuclear prelamin A recognition factor | -0.00518902 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00518775 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) | -0.00518393 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00518216 |
| DSE | dermatan sulfate epimerase | -0.00517957 |
| PSCA | prostate stem cell antigen | -0.00517906 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00517706 |
| ELOB | elongin B | -0.00517652 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00517399 |
| EPHB4 | EPH receptor B4 | -0.00513628 |
| KLC1 | kinesin light chain 1 | -0.00512431 |
| TPM3 | tropomyosin 3 | -0.00512048 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00510223 |
| DAP | death-associated protein | -0.00509725 |
| MCOLN1 | mucolipin 1 | -0.00509591 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | -0.00509436 |
| ABHD17A | abhydrolase domain containing 17A | -0.00509417 |
| APH1A | APH1A gamma secretase subunit | -0.00508608 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00508485 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00508483 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00508378 |
| ANGPT1 | angiopoietin 1 | -0.00508134 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00507897 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.00507797 |
| KIAA0100 | KIAA0100 | -0.00507694 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00507525 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | -0.00507506 |
| LSP1 | lymphocyte-specific protein 1 | -0.0050642 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00504211 |
| UNG | uracil-DNA glycosylase | -0.00503358 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00503292 |
