| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | vacuolar protein sorting 35 homolog (S. cerevisiae)|This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 55737) |
| External Link | https://ncbi.nlm.nih.gov/gene/55737 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the VPS35 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0222249 |
| TFF1 | trefoil factor 1 | 0.018939 |
| KRT7 | keratin 7, type II | 0.0180117 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0157184 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0128757 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0126921 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0121572 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0119247 |
| PERP | PERP, TP53 apoptosis effector | 0.0111511 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0111186 |
| ANXA3 | annexin A3 | 0.0110393 |
| OXTR | oxytocin receptor | 0.0109802 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0107623 |
| S100P | S100 calcium binding protein P | 0.0104118 |
| GLOD4 | glyoxalase domain containing 4 | 0.0103702 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0100726 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00986196 |
| TRIM29 | tripartite motif containing 29 | 0.00960554 |
| NEBL | nebulette | 0.00955551 |
| TPD52L1 | tumor protein D52-like 1 | 0.00934813 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0093179 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00909549 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00905462 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00891542 |
| PDZK1 | PDZ domain containing 1 | 0.00888542 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.00883216 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0088038 |
| PSCA | prostate stem cell antigen | 0.00864842 |
| VLDLR | very low density lipoprotein receptor | 0.00858426 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00853883 |
| ABLIM1 | actin binding LIM protein 1 | 0.00852842 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00839337 |
| LYZ | lysozyme | 0.00834355 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00830351 |
| MGLL | monoglyceride lipase | 0.00828711 |
| POR | P450 (cytochrome) oxidoreductase | 0.00818096 |
| MFAP5 | microfibrillar associated protein 5 | 0.00813056 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00812424 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00804447 |
| VNN1 | vanin 1 | 0.00801067 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00800237 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.0079933 |
| PLXNC1 | plexin C1 | 0.00791269 |
| NTS | neurotensin | 0.00779573 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00777327 |
| LASP1 | LIM and SH3 protein 1 | 0.00774989 |
| TUFT1 | tuftelin 1 | 0.00771459 |
| ACKR3 | atypical chemokine receptor 3 | 0.0076451 |
| CPD | carboxypeptidase D | 0.00757837 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00755644 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0075363 |
| KYNU | kynureninase | 0.00752616 |
| ANXA1 | annexin A1 | 0.00745208 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00738025 |
| STK10 | serine/threonine kinase 10 | 0.00737485 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00736202 |
| NEFH | neurofilament, heavy polypeptide | 0.00721717 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00717883 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.0071728 |
| IFI44L | interferon-induced protein 44-like | 0.00714245 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00712465 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00702221 |
| CHGB | chromogranin B | 0.00701923 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00701915 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00700045 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.0069959 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00697094 |
| ARCN1 | archain 1 | 0.00695966 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00695949 |
| MANSC1 | MANSC domain containing 1 | 0.00692917 |
| REEP1 | receptor accessory protein 1 | 0.0069283 |
| PROM1 | prominin 1 | 0.00690949 |
| NAV3 | neuron navigator 3 | 0.0068341 |
| TLR4 | toll-like receptor 4 | 0.00677358 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00674892 |
| PFKP | phosphofructokinase, platelet | 0.00674344 |
| DSP | desmoplakin | 0.00670778 |
| QDPR | quinoid dihydropteridine reductase | 0.00669762 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.00665706 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00664128 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00662841 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00661474 |
| MYOF | myoferlin | 0.00660565 |
| BICC1 | BicC family RNA binding protein 1 | 0.00656123 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00654444 |
| L1CAM | L1 cell adhesion molecule | 0.0065126 |
| MEIS1 | Meis homeobox 1 | 0.00643893 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00643722 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0064372 |
| COBL | cordon-bleu WH2 repeat protein | 0.00642638 |
| EPCAM | epithelial cell adhesion molecule | 0.00641169 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 0.00640526 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00638993 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00637512 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00636383 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00629426 |
| S100A8 | S100 calcium binding protein A8 | 0.0062935 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00629066 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.0062825 |
| KRT18 | keratin 18, type I | 0.00624618 |
| FHL1 | four and a half LIM domains 1 | 0.00624447 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00623478 |
| CLGN | calmegin | 0.00622573 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 | 0.00621941 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00621148 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00620491 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.00611777 |
| GOLGA8A | golgin A8 family, member A | 0.00611628 |
| MYBPC1 | myosin binding protein C, slow type | 0.00611394 |
| MFSD6 | major facilitator superfamily domain containing 6 | 0.00609931 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | 0.00607465 |
| EHBP1 | EH domain binding protein 1 | 0.0060468 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00604499 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00604178 |
| TRIP13 | thyroid hormone receptor interactor 13 | 0.00603381 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00602652 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | 0.00602013 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00599553 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.00598688 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00598396 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00597928 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00597754 |
| MX1 | MX dynamin-like GTPase 1 | 0.00597722 |
| DCN | decorin | 0.00597362 |
| HOMER1 | homer scaffolding protein 1 | 0.0059439 |
| DACH1 | dachshund family transcription factor 1 | 0.00593747 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00592099 |
| MX2 | MX dynamin-like GTPase 2 | 0.0059091 |
| MAGEA12 | melanoma antigen family A12 | 0.00588955 |
| IQCG | IQ motif containing G | 0.00587369 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00587355 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00584862 |
| FMO1 | flavin containing monooxygenase 1 | 0.0058449 |
| KAZN | kazrin, periplakin interacting protein | 0.00583772 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00583655 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00583625 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.00582934 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00581109 |
| CYBRD1 | cytochrome b reductase 1 | 0.00579392 |
| SOSTDC1 | sclerostin domain containing 1 | 0.00577703 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00576772 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00574646 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00573325 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00572504 |
| FLNB | filamin B, beta | 0.00571358 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | 0.00571205 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00570121 |
| YIPF5 | Yip1 domain family, member 5 | 0.0056899 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00568651 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00567918 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.00567907 |
| GNAS | GNAS complex locus | 0.00567369 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00565636 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00565336 |
| GOLT1B | golgi transport 1B | 0.00565251 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00564172 |
| TJP2 | tight junction protein 2 | 0.00561939 |
| CD164 | CD164 molecule, sialomucin | 0.00560078 |
| MORC4 | MORC family CW-type zinc finger 4 | 0.00559372 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00558382 |
| CLTB | clathrin, light chain B | 0.00556962 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | 0.00555921 |
| IFI44 | interferon-induced protein 44 | 0.00554184 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00551398 |
| MB | myoglobin | 0.00549662 |
| EMX2 | empty spiracles homeobox 2 | 0.00549389 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00549031 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00548881 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00548809 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.00548755 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00548563 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00546109 |
| CCN2 | cellular communication network factor 2 | 0.00545598 |
| LXN | latexin | 0.00545364 |
| KRT23 | keratin 23, type I | 0.0054535 |
| TMEM176B | transmembrane protein 176B | 0.00544067 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00542614 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00541525 |
| MED23 | mediator complex subunit 23 | 0.0054006 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00539796 |
| GRAMD2B | GRAM domain containing 2B | 0.00537885 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00537495 |
| CLIC3 | chloride intracellular channel 3 | 0.00536373 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00535218 |
| ANOS1 | anosmin 1 | 0.00533752 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 | 0.00533046 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.00532725 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.00532146 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00528889 |
| WWC1 | WW and C2 domain containing 1 | 0.005286 |
| WIF1 | WNT inhibitory factor 1 | 0.00526792 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00526229 |
| LEPR | leptin receptor | 0.00525356 |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.00524547 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0052285 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00521608 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.00521559 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00518608 |
| SH3GL2 | SH3-domain GRB2-like 2 | 0.00516436 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 | 0.00516389 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00515763 |
| PLCB4 | phospholipase C, beta 4 | 0.00514806 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00513755 |
| FAM198B | family with sequence similarity 198, member B | 0.00513499 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00512863 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00512838 |
| JUNB | jun B proto-oncogene | 0.00511324 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00511192 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00510479 |
| KRT8 | keratin 8, type II | 0.00510407 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 | 0.00509724 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00509587 |
| MLF1 | myeloid leukemia factor 1 | 0.00507642 |
| CORO1C | coronin, actin binding protein, 1C | 0.00507518 |
| RNFT1 | ring finger protein, transmembrane 1 | 0.00506983 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 0.00505475 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00503186 |
| MAGEA3 | melanoma antigen family A3 | 0.00502339 |
| LOC105375355 | uroplakin-3b | 0.00501925 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 0.0050189 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00501272 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.00500502 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00499962 |
| FAM107A | family with sequence similarity 107, member A | 0.00499719 |
| PODXL | podocalyxin-like | 0.00499656 |
| VCAN | versican | 0.00497386 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.00497294 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00497213 |
| NXN | nucleoredoxin | 0.00496343 |
| TNNC1 | troponin C type 1 (slow) | 0.00496236 |
| TRIM16 | tripartite motif containing 16 | 0.00495238 |
| CLU | clusterin | 0.00495094 |
| FBN2 | fibrillin 2 | 0.00494607 |
| SELL | selectin L | 0.00494576 |
| HLA-F | major histocompatibility complex, class I, F | 0.00494337 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00493192 |
| TBC1D30 | TBC1 domain family, member 30 | 0.00492299 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00491465 |
| MGST2 | microsomal glutathione S-transferase 2 | 0.00490725 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00489411 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.0048922 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00488911 |
| TFF2 | trefoil factor 2 | 0.00486876 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00486864 |
| KLK6 | kallikrein-related peptidase 6 | 0.00486796 |
| HIST3H2A | histone cluster 3, H2a | 0.00486111 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.0048564 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.00484337 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00484113 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0153201 |
| MMP9 | matrix metallopeptidase 9 | -0.0142907 |
| POU2AF1 | POU class 2 associating factor 1 | -0.0141493 |
| PTK2 | protein tyrosine kinase 2 | -0.0118675 |
| NVL | nuclear VCP-like | -0.0118373 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.0115745 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0115039 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0112937 |
| CNN3 | calponin 3, acidic | -0.0110969 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0105853 |
| RNF167 | ring finger protein 167 | -0.0105078 |
| VEGFA | vascular endothelial growth factor A | -0.0104136 |
| SIRT3 | sirtuin 3 | -0.0101032 |
| FRZB | frizzled-related protein | -0.00982274 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00956464 |
| CD9 | CD9 molecule | -0.00947758 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | -0.00920673 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00900497 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00864835 |
| PRKCB | protein kinase C, beta | -0.00859819 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00844402 |
| CHKB | choline kinase beta | -0.00836754 |
| FGB | fibrinogen beta chain | -0.00824015 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00822044 |
| HP | haptoglobin | -0.00820632 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00813846 |
| IPO13 | importin 13 | -0.00798419 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00789369 |
| CST7 | cystatin F (leukocystatin) | -0.0078483 |
| BCHE | butyrylcholinesterase | -0.0077439 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00765781 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.00764918 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0076417 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00762754 |
| CD19 | CD19 molecule | -0.00754305 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00743639 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00742939 |
| H1-0 | H1.0 linker histone | -0.00738883 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00738732 |
| CCND2 | cyclin D2 | -0.00735173 |
| FGG | fibrinogen gamma chain | -0.00728803 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00726336 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00720843 |
| CD81 | CD81 molecule | -0.00718686 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00711357 |
| CD27 | CD27 molecule | -0.00710945 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00706051 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.00704651 |
| REG1A | regenerating islet-derived 1 alpha | -0.00693276 |
| COL2A1 | collagen, type II, alpha 1 | -0.00688849 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00688633 |
| PLN | phospholamban | -0.00679499 |
| SELENBP1 | selenium binding protein 1 | -0.00678903 |
| ORM1 | orosomucoid 1 | -0.00674018 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00669794 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00669708 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00657932 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00655248 |
| ARSL | arylsulfatase L | -0.0065231 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00639006 |
| FN1 | fibronectin 1 | -0.00635266 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00630621 |
| TRIB2 | tribbles pseudokinase 2 | -0.00630295 |
| LCN2 | lipocalin 2 | -0.00629641 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00627317 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00625852 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00624507 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00624504 |
| GSPT2 | G1 to S phase transition 2 | -0.00618974 |
| OLFM4 | olfactomedin 4 | -0.00616396 |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | -0.00615786 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00613408 |
| FGA | fibrinogen alpha chain | -0.00608451 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00606915 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00605399 |
| CA12 | carbonic anhydrase XII | -0.00605058 |
| BRD4 | bromodomain containing 4 | -0.00605014 |
| ITGA8 | integrin, alpha 8 | -0.00604221 |
| LEFTY1 | left-right determination factor 1 | -0.00603833 |
| CP | ceruloplasmin (ferroxidase) | -0.00602493 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00602453 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00600262 |
| AIM2 | absent in melanoma 2 | -0.00599138 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | -0.00597256 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | -0.00597107 |
| MAOA | monoamine oxidase A | -0.00593848 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00592889 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00592544 |
| NUTF2 | nuclear transport factor 2 | -0.00591547 |
| FAM46C | family with sequence similarity 46, member C | -0.00590412 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.0058972 |
| CDC20 | cell division cycle 20 | -0.00588746 |
| COCH | cochlin | -0.00587062 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.00582713 |
| PAX5 | paired box 5 | -0.00580077 |
| C4BPA | complement component 4 binding protein, alpha | -0.00579235 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00577014 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00576158 |
| PDE9A | phosphodiesterase 9A | -0.0057581 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.00574342 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00573849 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00572653 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00572532 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00571681 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00570082 |
| CD8A | CD8a molecule | -0.00569722 |
| CDC42 | cell division cycle 42 | -0.00566437 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.00566242 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0056492 |
| KRT1 | keratin 1, type II | -0.00564157 |
| TCL1B | T-cell leukemia/lymphoma 1B | -0.00561979 |
| TSPAN7 | tetraspanin 7 | -0.0056194 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00561559 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00557972 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0055629 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | -0.00555459 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 | -0.00555232 |
| C1S | complement component 1, s subcomponent | -0.00554909 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase | -0.00553765 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00553408 |
| KLF13 | Kruppel-like factor 13 | -0.00553225 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00551997 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00548359 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00547055 |
| E2F2 | E2F transcription factor 2 | -0.00545694 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.00545103 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00543271 |
| FOXO1 | forkhead box O1 | -0.005367 |
| CLEC5A | C-type lectin domain family 5, member A | -0.0053601 |
| PENK | proenkephalin | -0.00534594 |
| FAM3C | family with sequence similarity 3, member C | -0.00532109 |
| ARG1 | arginase 1 | -0.0053004 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00528122 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | -0.00528058 |
| PIGR | polymeric immunoglobulin receptor | -0.00526649 |
| A2M | alpha-2-macroglobulin | -0.00526149 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.00524492 |
| RASL12 | RAS-like, family 12 | -0.0052411 |
| ENAH | enabled homolog (Drosophila) | -0.00521862 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00521094 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00520484 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00515459 |
| ACAN | aggrecan | -0.00515205 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00514784 |
| XIC | X chromosome inactivation center | -0.00512678 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00511803 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00510813 |
| GDF3 | growth differentiation factor 3 | -0.00510575 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00509939 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00508746 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) | -0.00507802 |
| DENND1B | DENN/MADD domain containing 1B | -0.00507287 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00505969 |
| CTSK | cathepsin K | -0.00502586 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | -0.00502559 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | -0.00502488 |
| CDSN | corneodesmosin | -0.00502054 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00499935 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00497022 |
| MT1E | metallothionein 1E | -0.00495874 |
| SERPINA4 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 | -0.0049586 |
| FASN | fatty acid synthase | -0.00495531 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00494549 |
| DDN | dendrin | -0.00493868 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00492327 |
| BPI | bactericidal/permeability-increasing protein | -0.0049132 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.00490126 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00486244 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00485147 |
| TIPRL | TOR signaling pathway regulator | -0.00485103 |
| EPX | eosinophil peroxidase | -0.00484055 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00483658 |
| PKP1 | plakophilin 1 | -0.00483303 |
| RBM34 | RNA binding motif protein 34 | -0.00482732 |
| MALL | mal, T-cell differentiation protein-like | -0.00482724 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.00481818 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00481602 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00480666 |
| MMP11 | matrix metallopeptidase 11 | -0.0047968 |
| VPREB3 | pre-B lymphocyte 3 | -0.00479588 |
| PLAU | plasminogen activator, urokinase | -0.0047909 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00478123 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.0047774 |
| C1R | complement component 1, r subcomponent | -0.00476497 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00475213 |
| H1-4 | H1.4 linker histone, cluster member | -0.00475053 |
| NARF | nuclear prelamin A recognition factor | -0.00474876 |
| NOTCH3 | notch 3 | -0.00474808 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00473775 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00473587 |
| PAEP | progestagen-associated endometrial protein | -0.00472392 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00472343 |
| ZNF580 | zinc finger protein 580 | -0.00472096 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00471855 |
| CLC | Charcot-Leyden crystal galectin | -0.00471144 |
| SPEG | SPEG complex locus | -0.00470017 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0046901 |
| FBXO28 | F-box protein 28 | -0.00468615 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00468304 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | -0.00467542 |
| TSNAX | translin-associated factor X | -0.00467355 |
| FGL1 | fibrinogen-like 1 | -0.00465976 |
| NELL2 | NEL-like 2 (chicken) | -0.00465662 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00465082 |
| CLMN | calmin (calponin-like, transmembrane) | -0.00464343 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.00464062 |
| LSM12 | LSM12 homolog (S. cerevisiae) | -0.00462426 |
| RORA | RAR-related orphan receptor A | -0.00462207 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00462142 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00461191 |
| TMEM87A | transmembrane protein 87A | -0.00456849 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 | -0.00456355 |
| STAG3 | stromal antigen 3 | -0.00455515 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D | -0.00454612 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00454532 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00453105 |
| ADORA2B | adenosine A2b receptor | -0.00453057 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.00452945 |
| KRT15 | keratin 15, type I | -0.00452067 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.0044974 |
| TSPOAP1 | TSPO associated protein 1 | -0.00448816 |
| PTMS | parathymosin | -0.00448548 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00447882 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.00447166 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00445735 |
| PLS3 | plastin 3 | -0.00445661 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.0044548 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00445357 |
| MINK1 | misshapen-like kinase 1 | -0.00445156 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00445067 |
| KIAA0226L | KIAA0226-like | -0.0044497 |
| SYBU | syntabulin (syntaxin-interacting) | -0.0044495 |
| SIKE1 | suppressor of IKBKE 1 | -0.00444575 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.00442412 |
| CPNE7 | copine VII | -0.00442055 |
| ZG16 | zymogen granule protein 16 | -0.00441545 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00439758 |
| MT1G | metallothionein 1G | -0.00439583 |
| SLAMF7 | SLAM family member 7 | -0.00439476 |
| PEX6 | peroxisomal biogenesis factor 6 | -0.00439348 |
| MMP13 | matrix metallopeptidase 13 | -0.00439296 |
| NRN1 | neuritin 1 | -0.00438324 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00437724 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.00437668 |
| RAP2C | RAP2C, member of RAS oncogene family | -0.00437139 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00437098 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene | -0.00436728 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0043606 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00435915 |
