VTCN1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description V-set domain containing T cell activation inhibitor 1|This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] (NCBI Entrez Gene Database, 79679)
External Link https://ncbi.nlm.nih.gov/gene/79679
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Genes

500 genes differentially expressed following the VTCN1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0261232
TFF1 trefoil factor 1 0.0227977
TFF3 trefoil factor 3 (intestinal) 0.0182326
NTS neurotensin 0.0166784
AGR2 anterior gradient 2 0.015514
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0147681
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0146495
BIRC5 baculoviral IAP repeat containing 5 0.0144741
MMP12 matrix metallopeptidase 12 0.0143458
NUSAP1 nucleolar and spindle associated protein 1 0.0140564
CCNA2 cyclin A2 0.0138338
CD200 CD200 molecule 0.0137105
TATDN2 TatD DNase domain containing 2 0.0135703
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0127898
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.0127673
DPYSL3 dihydropyrimidinase-like 3 0.0123441
PBX1 pre-B-cell leukemia homeobox 1 0.0122008
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.0121951
KIF20A kinesin family member 20A 0.0121722
LGALS13 lectin, galactoside-binding, soluble, 13 0.0120361
PRC1 protein regulator of cytokinesis 1 0.0119955
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.0118319
SUB1 SUB1 homolog (S. cerevisiae) 0.0113465
HMGB2 high mobility group box 2 0.0113142
ASF1B anti-silencing function 1B histone chaperone 0.0111667
PLN phospholamban 0.0110568
LMNB1 lamin B1 0.0109135
HBB hemoglobin, beta 0.0108551
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.010834
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.0107696
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0107687
MPO myeloperoxidase 0.0107222
CLCA1 chloride channel accessory 1 0.0106417
SET SET nuclear proto-oncogene 0.0103998
CEP55 centrosomal protein 55kDa 0.010296
PCSK1 proprotein convertase subtilisin/kexin type 1 0.0102087
PSIP1 PC4 and SFRS1 interacting protein 1 0.0101855
CDCA3 cell division cycle associated 3 0.0101842
TRMT5 tRNA methyltransferase 5 0.0101836
SORD sorbitol dehydrogenase 0.0101479
KIF15 kinesin family member 15 0.0101424
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.0101181
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.0101085
GCH1 GTP cyclohydrolase 1 0.0100192
ELANE elastase, neutrophil expressed 0.0100125
PSRC1 proline/serine-rich coiled-coil 1 0.00999587
OIP5 Opa interacting protein 5 0.00998525
RNASEH2A ribonuclease H2, subunit A 0.00996574
SPC25 SPC25, NDC80 kinetochore complex component 0.00995387
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00994759
MAP2K6 mitogen-activated protein kinase kinase 6 0.00994149
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00993835
MYH11 myosin, heavy chain 11, smooth muscle 0.00985239
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.0098444
OLFM1 olfactomedin 1 0.00979027
AURKB aurora kinase B 0.00972335
GREB1 growth regulation by estrogen in breast cancer 1 0.00971368
SMC2 structural maintenance of chromosomes 2 0.00967293
CD99 CD99 molecule 0.00965762
SRSF1 serine/arginine-rich splicing factor 1 0.00963899
ANXA6 annexin A6 0.00945523
CLIC4 chloride intracellular channel 4 0.00939107
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00936415
FOXM1 forkhead box M1 0.00936413
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00929512
AKAP7 A kinase (PRKA) anchor protein 7 0.00924694
KIF5C kinesin family member 5C 0.00923456
GLOD4 glyoxalase domain containing 4 0.00918936
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.00907359
MDFIC MyoD family inhibitor domain containing 0.00905941
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00902964
LMNB2 lamin B2 0.00901163
HMGB3 high mobility group box 3 0.00900126
C3ORF14 chromosome 3 open reading frame 14 0.00897133
NEK2 NIMA-related kinase 2 0.00895198
TDP1 tyrosyl-DNA phosphodiesterase 1 0.00894841
STMN1 stathmin 1 0.00892679
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00892272
CDKN3 cyclin-dependent kinase inhibitor 3 0.00891547
NUP37 nucleoporin 37kDa 0.00886796
DEFA6 defensin, alpha 6, Paneth cell-specific 0.00882178
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0088082
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00880649
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00875444
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00875343
TYRP1 tyrosinase-related protein 1 0.00874883
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00870413
RHOA ras homolog family member A 0.00869104
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.0086896
CDCA4 cell division cycle associated 4 0.00864563
ITM2A integral membrane protein 2A 0.00861234
NCAPD3 non-SMC condensin II complex, subunit D3 0.00860215
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00859849
NCAPG2 non-SMC condensin II complex, subunit G2 0.00858178
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00858013
PPA2 pyrophosphatase (inorganic) 2 0.00856412
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 0.00849858
SI sucrase-isomaltase (alpha-glucosidase) 0.00847315
PBK PDZ binding kinase 0.00846737
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00844798
KIF18B kinesin family member 18B 0.00839769
PGD phosphogluconate dehydrogenase 0.00834604
FGL2 fibrinogen-like 2 0.00833652
TPX2 TPX2, microtubule-associated 0.00832799
CDC20 cell division cycle 20 0.00831535
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00830445
MCM2 minichromosome maintenance complex component 2 0.00829308
RBBP4 retinoblastoma binding protein 4 0.00829173
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00827425
EPHB2 EPH receptor B2 0.00826452
FBXO5 F-box protein 5 0.00823508
BCLAF1 BCL2-associated transcription factor 1 0.00821242
CNN1 calponin 1, basic, smooth muscle 0.00820875
SEPHS1 selenophosphate synthetase 1 0.00820225
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00818941
RAD23B RAD23 homolog B (S. cerevisiae) 0.00818905
ABHD10 abhydrolase domain containing 10 0.00818508
OLFM4 olfactomedin 4 0.00817816
HMGB1 high mobility group box 1 0.00816057
CDC25B cell division cycle 25B 0.00811692
GCA grancalcin, EF-hand calcium binding protein 0.00811049
RPA3 replication protein A3, 14kDa 0.00806644
CD2 CD2 molecule 0.00806412
TCF21 transcription factor 21 0.00800655
RFC3 replication factor C (activator 1) 3, 38kDa 0.00800324
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00799993
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00797855
ADAM28 ADAM metallopeptidase domain 28 0.00792395
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00792199
KIF1B kinesin family member 1B 0.00791345
ECT2 epithelial cell transforming 2 0.00790486
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00790412
UBE2N ubiquitin-conjugating enzyme E2N 0.00788852
HOPX HOP homeobox 0.007855
PTTG1 pituitary tumor-transforming 1 0.0077987
GMDS GDP-mannose 4,6-dehydratase 0.00778566
CPA3 carboxypeptidase A3 (mast cell) 0.00777361
DHCR7 7-dehydrocholesterol reductase 0.00774713
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.00774358
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00773648
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00770695
ICMT isoprenylcysteine carboxyl methyltransferase 0.00768008
RRM2 ribonucleotide reductase M2 0.0076773
ENO2 enolase 2 (gamma, neuronal) 0.00767119
HEPH hephaestin 0.00766973
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.00759942
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00757578
DHFR dihydrofolate reductase 0.00753117
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00751893
LBR lamin B receptor 0.00751514
ZNF589 zinc finger protein 589 0.00747243
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00746175
GUCY2C guanylate cyclase 2C 0.00744689
ASCL1 achaete-scute family bHLH transcription factor 1 0.00744106
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00744085
RANBP1 RAN binding protein 1 0.00740668
UBE2C ubiquitin-conjugating enzyme E2C 0.00739768
MSH2 mutS homolog 2 0.0073847
PDLIM3 PDZ and LIM domain 3 0.00738376
KANK2 KN motif and ankyrin repeat domains 2 0.00737755
LIG1 ligase I, DNA, ATP-dependent 0.00737221
GSTA4 glutathione S-transferase alpha 4 0.00735228
TMEM38B transmembrane protein 38B 0.00731995
TFDP1 transcription factor Dp-1 0.00731511
TMPO thymopoietin 0.00731473
SPAG5 sperm associated antigen 5 0.00730971
COMMD10 COMM domain containing 10 0.00730622
ACE2 angiotensin I converting enzyme 2 0.00729909
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.00729504
CDK1 cyclin-dependent kinase 1 0.00729205
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00726932
VBP1 von Hippel-Lindau binding protein 1 0.00724182
DDHD2 DDHD domain containing 2 0.0072283
SPARCL1 SPARC-like 1 (hevin) 0.007217
GPA33 glycoprotein A33 (transmembrane) 0.00720862
ILF2 interleukin enhancer binding factor 2 0.00720423
FGFR3 fibroblast growth factor receptor 3 0.00718833
MCUB mitochondrial calcium uniporter dominant negative subunit beta 0.00718241
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00717006
TSPAN8 tetraspanin 8 0.00713607
DCXR dicarbonyl/L-xylulose reductase 0.00713577
AMD1 adenosylmethionine decarboxylase 1 0.00712392
TSPAN6 tetraspanin 6 0.0071193
NOVA1 neuro-oncological ventral antigen 1 0.00710953
BDH1 3-hydroxybutyrate dehydrogenase, type 1 0.00708625
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.00705962
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00705622
CENPF centromere protein F, 350/400kDa 0.00705127
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00704785
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00704763
DCK deoxycytidine kinase 0.00703717
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.00702099
ESD esterase D 0.00702068
MTARC1 mitochondrial amidoxime reducing component 1 0.00700334
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.00699634
LMOD1 leiomodin 1 (smooth muscle) 0.00698836
MCM6 minichromosome maintenance complex component 6 0.0069784
SNRPA small nuclear ribonucleoprotein polypeptide A 0.00695831
SYNGR3 synaptogyrin 3 0.00694579
BTNL8 butyrophilin-like 8 0.00691313
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00690941
CENPX centromere protein X 0.00689812
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.00687723
H1-10 H1.10 linker histone 0.0068749
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00686493
RPS5 ribosomal protein S5 0.00684608
GEMIN2 gem (nuclear organelle) associated protein 2 0.00684422
DES desmin 0.00684331
CNOT8 CCR4-NOT transcription complex, subunit 8 0.00683851
SUCLG1 succinate-CoA ligase, alpha subunit 0.00683659
ACTB actin, beta 0.00682275
EML4 echinoderm microtubule associated protein like 4 0.00681057
PXMP2 peroxisomal membrane protein 2, 22kDa 0.00680746
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00680033
FANCG Fanconi anemia, complementation group G 0.00678699
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00678612
MEP1A meprin A, alpha (PABA peptide hydrolase) 0.00678559
CPVL carboxypeptidase, vitellogenic-like 0.00677068
RMI1 RecQ mediated genome instability 1 0.00677016
PRKD3 protein kinase D3 0.00676391
STOML2 stomatin (EPB72)-like 2 0.00676065
PUM2 pumilio RNA-binding family member 2 0.00675625
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00675442
RACGAP1 Rac GTPase activating protein 1 0.00675032
MCM10 minichromosome maintenance complex component 10 0.00675011
PTTG3P pituitary tumor-transforming 3, pseudogene 0.00674821
CDT1 chromatin licensing and DNA replication factor 1 0.00674442
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00674037
CCNB1 cyclin B1 0.00673992
PDZRN3 PDZ domain containing ring finger 3 0.00673938
THYN1 thymocyte nuclear protein 1 0.00672856
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00672551
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00671807
PARPBP PARP1 binding protein 0.00671727
TIMELESS timeless circadian clock 0.006717
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00671668
PCLAF PCNA clamp associated factor 0.00670801
GLO1 glyoxalase I 0.00670658
HAUS4 HAUS augmin-like complex, subunit 4 0.00670235
ATRAID all-trans retinoic acid-induced differentiation factor 0.00670116
NCAPD2 non-SMC condensin I complex, subunit D2 0.00669392
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.0066917
WDR61 WD repeat domain 61 0.00668075
PRMT1 protein arginine methyltransferase 1 0.00667257
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.006671
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00666919
TTK TTK protein kinase 0.00666643
ANXA13 annexin A13 0.00665558
SRP72 signal recognition particle 72kDa 0.00665377
CASC3 cancer susceptibility candidate 3 0.00665247

decreased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 -0.0216471
PEG10 paternally expressed 10 -0.0213376
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0183432
IFI44L interferon-induced protein 44-like -0.0180307
MX1 MX dynamin-like GTPase 1 -0.0179657
ATF3 activating transcription factor 3 -0.0176251
HMOX1 heme oxygenase 1 -0.0169135
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0166405
HIST1H2BD histone cluster 1, H2bd -0.015924
GNAS GNAS complex locus -0.0158986
ISG15 ISG15 ubiquitin-like modifier -0.0157908
CTSD cathepsin D -0.0156273
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0154876
GPNMB glycoprotein (transmembrane) nmb -0.0154726
HSPA1A heat shock 70kDa protein 1A -0.0153389
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0152168
HIST1H2AC histone cluster 1, H2ac -0.0151696
HTRA1 HtrA serine peptidase 1 -0.0150824
XIC X chromosome inactivation center -0.0149418
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.014815
PLK2 polo-like kinase 2 -0.0147401
KRT14 keratin 14, type I -0.0146217
CRYAB crystallin, alpha B -0.0138289
RGCC regulator of cell cycle -0.0136953
H1-2 H1.2 linker histone, cluster member -0.0135997
IFI6 interferon, alpha-inducible protein 6 -0.0133614
IER5 immediate early response 5 -0.0133368
FTH1 ferritin, heavy polypeptide 1 -0.0132495
MIR22HG MIR22 host gene -0.0132257
IRF7 interferon regulatory factor 7 -0.0131751
CD9 CD9 molecule -0.013146
MGLL monoglyceride lipase -0.0131339
PTK2B protein tyrosine kinase 2 beta -0.0128662
JAG1 jagged 1 -0.0126398
IPO13 importin 13 -0.0125673
SLPI secretory leukocyte peptidase inhibitor -0.0125531
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0125424
MET MET proto-oncogene, receptor tyrosine kinase -0.012528
ADIRF adipogenesis regulatory factor -0.012522
IFI44 interferon-induced protein 44 -0.0124828
MT1E metallothionein 1E -0.0122139
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.0121319
MT1X metallothionein 1X -0.0121192
MVP major vault protein -0.012094
ZMAT3 zinc finger, matrin-type 3 -0.0120255
TFPI2 tissue factor pathway inhibitor 2 -0.0120133
LYPD1 LY6/PLAUR domain containing 1 -0.0119103
EMP1 epithelial membrane protein 1 -0.0118539
DEFB1 defensin, beta 1 -0.0118327
SGK1 serum/glucocorticoid regulated kinase 1 -0.0116959
FN1 fibronectin 1 -0.0116879
CCL20 chemokine (C-C motif) ligand 20 -0.0114224
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0113861
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0113625
IL1B interleukin 1, beta -0.0112973
ASS1 argininosuccinate synthase 1 -0.0112623
ECM1 extracellular matrix protein 1 -0.0112103
GPR137B G protein-coupled receptor 137B -0.0111144
VEGFA vascular endothelial growth factor A -0.0111021
CFB complement factor B -0.0110116
MX2 MX dynamin-like GTPase 2 -0.0109396
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0109317
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.010859
IL1R1 interleukin 1 receptor, type I -0.0108356
TRIM8 tripartite motif containing 8 -0.0107337
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.0106856
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0106211
IGF2R insulin-like growth factor 2 receptor -0.0106137
RND3 Rho family GTPase 3 -0.0105301
CSRP2 cysteine and glycine-rich protein 2 -0.0104644
AMOTL2 angiomotin like 2 -0.0103878
FAM110B family with sequence similarity 110, member B -0.0103704
HOXC10 homeobox C10 -0.0103159
EFNA1 ephrin-A1 -0.010263
PLXNB2 plexin B2 -0.0102335
CTSA cathepsin A -0.0102277
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -0.0102057
SIK1 salt-inducible kinase 1 -0.010204
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.0101321
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.0101049
PXDC1 PX domain containing 1 -0.0101046
BCL3 B-cell CLL/lymphoma 3 -0.0100646
PLAAT3 phospholipase A and acyltransferase 3 -0.0100635
BTG1 B-cell translocation gene 1, anti-proliferative -0.0100244
AKAP9 A kinase (PRKA) anchor protein 9 -0.00985549
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00982653
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -0.00975161
HIST1H2BK histone cluster 1, H2bk -0.00972939
WASL Wiskott-Aldrich syndrome-like -0.0097255
CP ceruloplasmin (ferroxidase) -0.00971934
KRT7 keratin 7, type II -0.00967586
ANXA1 annexin A1 -0.00967465
TACSTD2 tumor-associated calcium signal transducer 2 -0.00964705
TRIM22 tripartite motif containing 22 -0.00963988
NEU1 sialidase 1 (lysosomal sialidase) -0.00958666
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00953675
SOX4 SRY (sex determining region Y)-box 4 -0.00950075
G0S2 G0/G1 switch 2 -0.0094907
FBN2 fibrillin 2 -0.00948058
IFRD1 interferon-related developmental regulator 1 -0.0094695
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00944717
BTG2 BTG family, member 2 -0.00943626
RRAGC Ras-related GTP binding C -0.00937495
TMBIM1 transmembrane BAX inhibitor motif containing 1 -0.00934456
TICAM1 toll-like receptor adaptor molecule 1 -0.00934113
THBS2 thrombospondin 2 -0.00931879
PLAUR plasminogen activator, urokinase receptor -0.00924745
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.009241
CCN2 cellular communication network factor 2 -0.00920886
TMEM140 transmembrane protein 140 -0.00917162
BIK BCL2-interacting killer (apoptosis-inducing) -0.00914487
CA12 carbonic anhydrase XII -0.00912402
SCPEP1 serine carboxypeptidase 1 -0.00911762
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00909789
TRIM29 tripartite motif containing 29 -0.00908856
SGCE sarcoglycan, epsilon -0.00901567
FOXD1 forkhead box D1 -0.00896378
OSBPL3 oxysterol binding protein-like 3 -0.0089514
NT5E 5'-nucleotidase, ecto (CD73) -0.00894488
GPX1 glutathione peroxidase 1 -0.00894274
NOTCH1 notch 1 -0.00892506
BLNK B-cell linker -0.00891851
LMNA lamin A/C -0.00889811
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00889746
TGFA transforming growth factor, alpha -0.00886136
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00886009
IGF1R insulin-like growth factor 1 receptor -0.00884863
CRABP2 cellular retinoic acid binding protein 2 -0.00883738
BEX4 brain expressed, X-linked 4 -0.00882267
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00875788
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00875776
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00871477
LAMB1 laminin, beta 1 -0.00871176
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00871065
JMJD6 jumonji domain containing 6 -0.00866765
TM9SF3 transmembrane 9 superfamily member 3 -0.00864949
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0086444
UPP1 uridine phosphorylase 1 -0.0086316
TUFT1 tuftelin 1 -0.00861611
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.0086138
SQSTM1 sequestosome 1 -0.00855355
JUP junction plakoglobin -0.00854507
OSBPL2 oxysterol binding protein-like 2 -0.00852133
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00852063
INHBA inhibin, beta A -0.00849861
LGALS3 lectin, galactoside-binding, soluble, 3 -0.0084961
S100A11 S100 calcium binding protein A11 -0.00848223
ZDHHC7 zinc finger, DHHC-type containing 7 -0.0084768
GRAMD2B GRAM domain containing 2B -0.00845453
KDM6B lysine (K)-specific demethylase 6B -0.00843008
ZNF91 zinc finger protein 91 -0.00842208
ALOX5 arachidonate 5-lipoxygenase -0.00841902
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00841745
ZBED2 zinc finger, BED-type containing 2 -0.0084055
KRT23 keratin 23, type I -0.00838832
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00838416
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00838077
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00836152
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00835567
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00834809
KLHL24 kelch-like family member 24 -0.00833479
MNT MAX network transcriptional repressor -0.0083321
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00831309
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00830922
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00828484
RFTN1 raftlin, lipid raft linker 1 -0.00828181
TRIB1 tribbles pseudokinase 1 -0.00824493
IFIH1 interferon induced with helicase C domain 1 -0.0082431
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -0.00822748
RAB9A RAB9A, member RAS oncogene family -0.00822125
ANPEP alanyl (membrane) aminopeptidase -0.00821191
ITGAV integrin, alpha V -0.00821058
SLC38A1 solute carrier family 38, member 1 -0.00820925
MT1G metallothionein 1G -0.00818569
TPST2 tyrosylprotein sulfotransferase 2 -0.00816314
GLRX glutaredoxin (thioltransferase) -0.00815552
BAMBI BMP and activin membrane-bound inhibitor -0.00814323
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -0.00810778
BGN biglycan -0.00809235
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00808369
FRMD4B FERM domain containing 4B -0.00805141
MT1H metallothionein 1H -0.00804563
RPS27L ribosomal protein S27-like -0.00804281
IL1RN interleukin 1 receptor antagonist -0.00800413
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00799544
FAT1 FAT atypical cadherin 1 -0.00798901
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -0.00794051
SDC4 syndecan 4 -0.00791027
SNAI2 snail family zinc finger 2 -0.00790131
ANGPTL4 angiopoietin-like 4 -0.00789284
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00788504
RRAGD Ras-related GTP binding D -0.0078842
ELF4 E74-like factor 4 (ets domain transcription factor) -0.00788133
DUSP14 dual specificity phosphatase 14 -0.00786923
SP100 SP100 nuclear antigen -0.00786896
KRT17 keratin 17, type I -0.00786812
C3 complement component 3 -0.00785084
DUSP6 dual specificity phosphatase 6 -0.00784969
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.00778556
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00778044
CADM1 cell adhesion molecule 1 -0.0077765
MXRA5 matrix-remodelling associated 5 -0.00777528
E2F3 E2F transcription factor 3 -0.00777422
EPHA2 EPH receptor A2 -0.00776216
GOLT1B golgi transport 1B -0.00775616
C5AR1 complement component 5a receptor 1 -0.00775052
DGKA diacylglycerol kinase, alpha 80kDa -0.00774057
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.0077397
MT1HL1 metallothionein 1H-like 1 -0.00773615
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.00772591
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00771884
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.0077176
N4BP1 NEDD4 binding protein 1 -0.00771258
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00771042
PLK3 polo-like kinase 3 -0.00770569
NPC1 Niemann-Pick disease, type C1 -0.00769949
PTK2 protein tyrosine kinase 2 -0.00769588
ZFP36 ZFP36 ring finger protein -0.00768779
KLF6 Kruppel-like factor 6 -0.00768616
ARL4C ADP-ribosylation factor-like 4C -0.00768025
HBEGF heparin-binding EGF-like growth factor -0.00767475
LY6E lymphocyte antigen 6 complex, locus E -0.00767032
AHNAK2 AHNAK nucleoprotein 2 -0.0076577
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00765596
PDLIM4 PDZ and LIM domain 4 -0.00765336
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00762602
GRN granulin -0.00761994
ZNF394 zinc finger protein 394 -0.00761316
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00760706
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.00759675
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00759078
SOWAHC sosondowah ankyrin repeat domain family member C -0.00757858
XAF1 XIAP associated factor 1 -0.00755223
VNN1 vanin 1 -0.00753852
AREG amphiregulin -0.0075377
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00752555
GPX4 glutathione peroxidase 4 -0.00751495
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.00750692
KCTD12 potassium channel tetramerization domain containing 12 -0.00749414
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00748948
ANKRD11 ankyrin repeat domain 11 -0.00748657
MDK midkine (neurite growth-promoting factor 2) -0.00747831
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00747159
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -0.00746216
MCOLN1 mucolipin 1 -0.00745063
FSCN1 fascin actin-bundling protein 1 -0.00743838
LAMC2 laminin, gamma 2 -0.00743042
NOTCH2NL notch 2 N-terminal like -0.00741404
ZFP36L1 ZFP36 ring finger protein-like 1 -0.00738106
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00737427