VTI1B Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description vesicle transport through interaction with t-SNAREs 1B| (NCBI Entrez Gene Database, 10490)
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Genes

285 genes differentially expressed following the VTI1B gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
IFITM10 interferon induced transmembrane protein 10 2.94082
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.94082
C12ORF71 chromosome 12 open reading frame 71 2.94082
TRIM74 tripartite motif containing 74 2.94082
HCRTR2 hypocretin (orexin) receptor 2 2.94082
ASB10 ankyrin repeat and SOCS box containing 10 2.94082
SKOR2 SKI family transcriptional corepressor 2 2.94082
GSTM5 glutathione S-transferase mu 5 2.94082
SH2D7 SH2 domain containing 7 2.94082
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 2.94082
PNMA5 paraneoplastic Ma antigen family member 5 2.94082
PDYN prodynorphin 2.94082
GFRA4 GDNF family receptor alpha 4 2.94082
TRIM17 tripartite motif containing 17 2.94082
HEATR9 HEAT repeat containing 9 2.94082
SLC46A2 solute carrier family 46, member 2 2.94082
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.94082
OR13C3 olfactory receptor, family 13, subfamily C, member 3 2.94082
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.94082
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 2.94082
TRAF3IP3 TRAF3 interacting protein 3 2.94082
LPO lactoperoxidase 2.94082
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.94082
MNX1 motor neuron and pancreas homeobox 1 2.94082
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 2.94082
CD22 CD22 molecule 2.94082
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.94082
FGF6 fibroblast growth factor 6 2.94082
ERAP2 endoplasmic reticulum aminopeptidase 2 2.94082
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 2.94082
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.94082
LGALS4 lectin, galactoside-binding, soluble, 4 2.94082
BFSP2 beaded filament structural protein 2, phakinin 2.94082
S100A5 S100 calcium binding protein A5 2.94082
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 2.94082
UMODL1 uromodulin-like 1 2.94082
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 2.94082
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2.94082
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.94082
TMEM40 transmembrane protein 40 2.94082
ACSL5 acyl-CoA synthetase long-chain family member 5 2.94082
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 2.94082
SPRR2A small proline-rich protein 2A 2.94082
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 2.94082
MCHR2 melanin-concentrating hormone receptor 2 2.94082
PTH1R parathyroid hormone 1 receptor 2.94082
CBARP CACN subunit beta associated regulatory protein 2.94082
CBLIF cobalamin binding intrinsic factor 2.94082
DIPK1C divergent protein kinase domain 1C 2.94082
ODAPH odontogenesis associated phosphoprotein 2.94082
H3C14 H3 clustered histone 14 2.94082
C17ORF114 chromosome 17 open reading frame 114 2.94082
PNMA6E PNMA family member 6E 2.94082
SPEGNB SPEG neighbor 2.94082
PNMA6F PNMA family member 6F 2.94082
WNT16 wingless-type MMTV integration site family, member 16 2.94082
MOV10L1 Mov10 RISC complex RNA helicase like 1 2.94082
HAL histidine ammonia-lyase 2.94082
NRN1 neuritin 1 2.94082
TAS2R5 taste receptor, type 2, member 5 2.94082
FPR2 formyl peptide receptor 2 2.94082
IZUMO4 IZUMO family member 4 2.94082
KLHL33 kelch-like family member 33 2.94082
PRB4 proline-rich protein BstNI subfamily 4 2.94082
CLDN5 claudin 5 2.94082
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.94082
BHLHA9 basic helix-loop-helix family, member a9 2.94082
TPTE transmembrane phosphatase with tensin homology 2.94082
GSC goosecoid homeobox 2.94082
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.94082
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.94082
SBSN suprabasin 2.94082
TACR2 tachykinin receptor 2 2.94082
BARX1 BARX homeobox 1 2.94082
ACKR5 atypical chemokine receptor 5 2.94082
ADAM20 ADAM metallopeptidase domain 20 2.94082
SLC36A3 solute carrier family 36, member 3 2.94082
KLK11 kallikrein-related peptidase 11 2.94082
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 2.94082
PCDH12 protocadherin 12 2.94082
COL17A1 collagen, type XVII, alpha 1 2.94082
ODF4 outer dense fiber of sperm tails 4 2.94082
CBX8 chromobox homolog 8 2.94082
CD248 CD248 molecule, endosialin 2.94082
APOC4 apolipoprotein C-IV 2.94082
APOC2 apolipoprotein C-II 2.94082
CPA4 carboxypeptidase A4 2.94082
KRT222 keratin 222, type II 2.94082
KLHL1 kelch-like family member 1 2.94082
EDN3 endothelin 3 2.94082
CLIC5 chloride intracellular channel 5 2.94082
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.94082
SPZ1 spermatogenic leucine zipper 1 2.94082
FBXO47 F-box protein 47 2.94082
EGR3 early growth response 3 2.94082
SHOX2 short stature homeobox 2 2.94082
RLF rearranged L-myc fusion 2.94082
GOLGA8T golgin A8 family, member T 2.94082
C22ORF31 chromosome 22 open reading frame 31 2.94082
CCDC78 coiled-coil domain containing 78 2.94082
CLEC18B C-type lectin domain family 18, member B 2.94082
C10ORF105 chromosome 10 open reading frame 105 2.94082
ITGA8 integrin, alpha 8 2.94082
GPR146 G protein-coupled receptor 146 2.94082
FAIM2 Fas apoptotic inhibitory molecule 2 2.94082
EFCC1 EF-hand and coiled-coil domain containing 1 2.94082
LGALS14 lectin, galactoside-binding, soluble, 14 2.94082
QRFP pyroglutamylated RFamide peptide 2.94082
PGR progesterone receptor 2.94082
SCNN1D sodium channel, non voltage gated 1 delta subunit 2.94082
ZC3H12D zinc finger CCCH-type containing 12D 2.94082
LRRC15 leucine rich repeat containing 15 2.94082
PCDHGB4 protocadherin gamma subfamily B, 4 2.94082
SLC25A52 solute carrier family 25, member 52 2.94082
FITM1 fat storage-inducing transmembrane protein 1 2.94082
LRRC38 leucine rich repeat containing 38 2.94082
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.94082
EPX eosinophil peroxidase 2.94082
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.94082
HEMGN hemogen 2.94082
DBX2 developing brain homeobox 2 2.94082
BPIFC BPI fold containing family C 2.94082
SLITRK1 SLIT and NTRK-like family, member 1 2.94082
FGF10 fibroblast growth factor 10 2.94082
DMRTC1B DMRT-like family C1B 2.94082
CHAT choline O-acetyltransferase 2.94082
ZPLD1 zona pellucida-like domain containing 1 2.94082
NAT16 N-acetyltransferase 16 (GCN5-related, putative) 2.94082
PADI1 peptidyl arginine deiminase, type I 2.94082
ACKR2 atypical chemokine receptor 2 2.94082
WDR72 WD repeat domain 72 2.94082
ALOX15B arachidonate 15-lipoxygenase, type B 2.94082
OR10G4 olfactory receptor, family 10, subfamily G, member 4 2.94082
EPOP elongin BC and polycomb repressive complex 2 associated protein 2.88016
MAMLD1 mastermind-like domain containing 1 2.85557
DCAF1 DDB1 and CUL4 associated factor 1 2.83595
METTL2B methyltransferase like 2B 2.83595
LBH limb bud and heart development 2.73159
C15ORF61 chromosome 15 open reading frame 61 2.66726
MATCAP1 microtubule associated tyrosine carboxypeptidase 1 2.66721
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae) 2.57765
RABL6 RAB, member RAS oncogene family-like 6 2.57144
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 2.56537
MTUS2 microtubule associated tumor suppressor candidate 2 2.5409
TRIP11 thyroid hormone receptor interactor 11 2.52615
WFDC10B WAP four-disulfide core domain 10B 2.46544
NWD1 NACHT and WD repeat domain containing 1 2.40177
LCN10 lipocalin 10 2.39755
TEX12 testis expressed 12 2.39755
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 2.37795
HOMER2 homer scaffolding protein 2 2.35684
SPATA9 spermatogenesis associated 9 2.32673
ZNF331 zinc finger protein 331 2.32673
SYNC syncoilin, intermediate filament protein 2.3188
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 2.31029
DPPA3 developmental pluripotency associated 3 2.30461
RBX1 ring-box 1, E3 ubiquitin protein ligase 2.30303
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.30044
RAB1B RAB1B, member RAS oncogene family 2.29418
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.27324
RRAS related RAS viral (r-ras) oncogene homolog 2.26703
EIF3K eukaryotic translation initiation factor 3, subunit K 2.25604
PLBD2 phospholipase B domain containing 2 2.22703
TRIML2 tripartite motif family-like 2 2.20452
SH2D2A SH2 domain containing 2A 2.20204
ZNF184 zinc finger protein 184 2.18897
HPSE2 heparanase 2 (inactive) 2.18838
SLMAP sarcolemma associated protein 2.181
CSNK1D casein kinase 1, delta 2.181
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.16662
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2.14403
SARS1 seryl-tRNA synthetase 1 2.11872
SYT14 synaptotagmin XIV 2.09195
IKZF5 IKAROS family zinc finger 5 (Pegasus) 2.085
SP3 Sp3 transcription factor 2.08186
PMM1 phosphomannomutase 1 2.07911
RBM4 RNA binding motif protein 4 2.07352
FAM221A family with sequence similarity 221, member A 2.04963
GJA1 gap junction protein, alpha 1, 43kDa 2.04963
ZFP57 ZFP57 zinc finger protein 2.04963
CCDC178 coiled-coil domain containing 178 2.04963
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 2.04603
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.0358
MYRIP myosin VIIA and Rab interacting protein 2.03395
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 2.03393
GSE1 Gse1 coiled-coil protein 2.02191
CSNK2A2 casein kinase 2, alpha prime polypeptide 2.02191
SCO2 SCO2 cytochrome c oxidase assembly protein 2.01631
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 2.01631

decreased expression

Symbol Name Standardized Value
ATG14 autophagy related 14 -2.94082
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -2.94082
NHSL1 NHS-like 1 -2.94082
CALY calcyon neuron-specific vesicular protein -2.94082
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -2.94082
PRDM2 PR domain containing 2, with ZNF domain -2.94082
RAI2 retinoic acid induced 2 -2.94082
H3-3B H3.3 histone B -2.94082
DGKI diacylglycerol kinase, iota -2.94082
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -2.94082
EFHD2 EF-hand domain family, member D2 -2.84929
FGF9 fibroblast growth factor 9 -2.83595
MEI1 meiosis inhibitor 1 -2.83595
CRYGB crystallin, gamma B -2.83595
NT5E 5'-nucleotidase, ecto (CD73) -2.83595
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -2.83595
KLLN killin, p53-regulated DNA replication inhibitor -2.83595
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -2.83595
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.83595
NPIPA6 nuclear pore complex interacting protein family, member A6 -2.83595
SH2D6 SH2 domain containing 6 -2.83595
PCDHB4 protocadherin beta 4 -2.83595
CFAP141 cilia and flagella associated protein 141 -2.83595
KASH5 KASH domain containing 5 -2.83595
PNLIPRP2 pancreatic lipase-related protein 2 -2.83595
CD70 CD70 molecule -2.83595
CLDN23 claudin 23 -2.83595
KLRF1 killer cell lectin-like receptor subfamily F, member 1 -2.83595
CIROZ ciliated left-right organizer protein containing ZP-N domains -2.83595
AMBP alpha-1-microglobulin/bikunin precursor -2.83595
CPED1 cadherin-like and PC-esterase domain containing 1 -2.83595
FAM3D family with sequence similarity 3, member D -2.83595
LURAP1L leucine rich adaptor protein 1-like -2.83595
EBI3 Epstein-Barr virus induced 3 -2.83595
FXYD2 FXYD domain containing ion transport regulator 2 -2.83595
PSD2 pleckstrin and Sec7 domain containing 2 -2.83595
HSPA1L heat shock 70kDa protein 1-like -2.83595
CCNI2 cyclin I family, member 2 -2.83595
RNF121 ring finger protein 121 -2.83595
RAD51AP2 RAD51 associated protein 2 -2.83595
CEND1 cell cycle exit and neuronal differentiation 1 -2.83595
LCNL1 lipocalin-like 1 -2.83595
EPHA3 EPH receptor A3 -2.83595
CAMK2B calcium/calmodulin-dependent protein kinase II beta -2.83595
EBF3 early B-cell factor 3 -2.83595
CELA2B chymotrypsin-like elastase family, member 2B -2.83595
CFDP1 craniofacial development protein 1 -2.83595
GJC2 gap junction protein, gamma 2, 47kDa -2.83595
TTC29 tetratricopeptide repeat domain 29 -2.83595
BAG2 BCL2-associated athanogene 2 -2.83595
MAGEA4 melanoma antigen family A4 -2.6741
TMPRSS11D transmembrane protease, serine 11D -2.6741
FHL2 four and a half LIM domains 2 -2.64826
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.64025
EFNB3 ephrin-B3 -2.63295
TMOD1 tropomodulin 1 -2.61345
SH2D5 SH2 domain containing 5 -2.6001
ZNF19 zinc finger protein 19 -2.57144
HINT3 histidine triad nucleotide binding protein 3 -2.42696
CD177 CD177 molecule -2.41933
FXR1 fragile X mental retardation, autosomal homolog 1 -2.41888
MMS22L MMS22-like, DNA repair protein -2.41888
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -2.37171
LHFPL4 lipoma HMGIC fusion partner-like 4 -2.36931
C19ORF44 chromosome 19 open reading frame 44 -2.32673
TENT4B terminal nucleotidyltransferase 4B -2.30044
CDK8 cyclin-dependent kinase 8 -2.29418
NGEF neuronal guanine nucleotide exchange factor -2.29418
ERLIN2 ER lipid raft associated 2 -2.27523
FAM78A family with sequence similarity 78, member A -2.27324
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like -2.27324
IRAG1 inositol 1,4,5-triphosphate receptor associated 1 -2.27324
ZNF221 zinc finger protein 221 -2.27324
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 -2.27324
FSCN3 fascin actin-bundling protein 3, testicular -2.27324
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.26703
FHIP2A FHF complex subunit HOOK interacting protein 2A -2.22893
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.21502
ZNF790 zinc finger protein 790 -2.20931
TPT1 tumor protein, translationally-controlled 1 -2.20452
COL16A1 collagen, type XVI, alpha 1 -2.20452
KLRG2 killer cell lectin-like receptor subfamily G, member 2 -2.20204
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 -2.13732
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 -2.13039
SYNPO synaptopodin -2.1265
NES nestin -2.11872
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.11063
FN1 fibronectin 1 -2.09765
APOOL apolipoprotein O-like -2.07352
TUBA1B tubulin, alpha 1b -2.06747
TULP3 tubby like protein 3 -2.05855
TANK TRAF family member-associated NFKB activator -2.04479
NT5C3A 5'-nucleotidase, cytosolic IIIA -2.01631
RGMA repulsive guidance molecule family member a -2.00565
RIPPLY3 ripply transcriptional repressor 3 -2.00457
SF3A2 splicing factor 3a, subunit 2, 66kDa -2.00457