VWF Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description von Willebrand factor|The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7450)
External Link http://www.ncbi.nlm.nih.gov/gene/7450
Similar Terms
Downloads & Tools

Genes

41 interacting proteins for VWF from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ALB albumin
AMBP alpha-1-microglobulin/bikunin precursor
APOA1 apolipoprotein A-I
ATXN7 ataxin 7
C3 complement component 3
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALR calreticulin
CFH complement factor H
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
F2 coagulation factor II (thrombin)
F8 coagulation factor VIII, procoagulant component
FURIN furin (paired basic amino acid cleaving enzyme)
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GP9 glycoprotein IX (platelet)
HRG histidine-rich glycoprotein
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
MAP3K3 mitogen-activated protein kinase kinase kinase 3
OPTN optineurin
PDIA4 protein disulfide isomerase family A, member 4
PRKCZ protein kinase C, zeta
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTK2 protein tyrosine kinase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SOCS4 suppressor of cytokine signaling 4
SYK spleen tyrosine kinase
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
UBC ubiquitin C
ZNF512B zinc finger protein 512B