Vacuole Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. (Gene Ontology, GO_0005773)
External Link http://amigo.geneontology.org/amigo/term/GO:0005773
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Genes

726 proteins localized to the Vacuole cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ARSK arylsulfatase family, member K 5.0
LMBRD1 LMBR1 domain containing 1 5.0
SLC37A3 solute carrier family 37, member 3 5.0
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 5.0
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 5.0
TBC1D5 TBC1 domain family, member 5 5.0
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 5.0
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 5.0
MCOLN1 mucolipin 1 5.0
SLC39A14 solute carrier family 39 (zinc transporter), member 14 5.0
CLCN4 chloride channel, voltage-sensitive 4 5.0
ATRAID all-trans retinoic acid-induced differentiation factor 5.0
TP53INP1 tumor protein p53 inducible nuclear protein 1 5.0
TP53INP2 tumor protein p53 inducible nuclear protein 2 5.0
SPAG9 sperm associated antigen 9 5.0
GABARAP GABA(A) receptor-associated protein 5.0
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 5.0
SPACA3 sperm acrosome associated 3 5.0
SPPL2B signal peptide peptidase like 2B 5.0
RAB23 RAB23, member RAS oncogene family 5.0
SFTPD surfactant protein D 5.0
ARSG arylsulfatase G 5.0
LITAF lipopolysaccharide-induced TNF factor 5.0
SLC30A2 solute carrier family 30 (zinc transporter), member 2 5.0
DRAM1 DNA-damage regulated autophagy modulator 1 5.0
DRAM2 DNA-damage regulated autophagy modulator 2 5.0
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 5.0
FFAR4 free fatty acid receptor 4 5.0
GPR137C G protein-coupled receptor 137C 5.0
GPR137B G protein-coupled receptor 137B 5.0
SNAP23 synaptosomal-associated protein, 23kDa 5.0
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 5.0
TRPV3 transient receptor potential cation channel, subfamily V, member 3 5.0
SLC26A11 solute carrier family 26 (anion exchanger), member 11 5.0
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 5.0
DTX3L deltex 3 like, E3 ubiquitin ligase 5.0
SLC39A8 solute carrier family 39 (zinc transporter), member 8 5.0
TMEM63A transmembrane protein 63A 5.0
VAMP8 vesicle-associated membrane protein 8 5.0
SEC13 SEC13 homolog (S. cerevisiae) 5.0
TMEM175 transmembrane protein 175 5.0
RHEB Ras homolog enriched in brain 5.0
CXCR2 chemokine (C-X-C motif) receptor 2 5.0
KCNK6 potassium channel, two pore domain subfamily K, member 6 5.0
TMEM150C transmembrane protein 150C 5.0
MTOR mechanistic target of rapamycin (serine/threonine kinase) 5.0
CTNS cystinosin, lysosomal cystine transporter 5.0
FNIP1 folliculin interacting protein 1 5.0
TMEM59 transmembrane protein 59 5.0
PRSS57 protease, serine, 57 5.0
WDR45B WD repeat domain 45B 5.0
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 5.0
CALCRL calcitonin receptor-like 5.0
CXCR4 chemokine (C-X-C motif) receptor 4 5.0
FTH1 ferritin, heavy polypeptide 1 5.0
UBQLN1 ubiquilin 1 5.0
UBQLN4 ubiquilin 4 5.0
DAPK2 death-associated protein kinase 2 5.0
ULK1 unc-51 like autophagy activating kinase 1 5.0
FYCO1 FYVE and coiled-coil domain containing 1 5.0
SEH1L SEH1-like (S. cerevisiae) 5.0
PDGFRB platelet-derived growth factor receptor, beta polypeptide 5.0
RUFY4 RUN and FYVE domain containing 4 5.0
MAPK15 mitogen-activated protein kinase 15 5.0
GLMP glycosylated lysosomal membrane protein 5.0
ANXA6 annexin A6 5.0
M6PR mannose-6-phosphate receptor (cation dependent) 5.0
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 5.0
TSC1 tuberous sclerosis 1 5.0
CLN5 ceroid-lipofuscinosis, neuronal 5 5.0
RAB7B RAB7B, member RAS oncogene family 5.0
SNX14 sorting nexin 14 5.0
ATG14 autophagy related 14 5.0
JMY junction mediating and regulatory protein, p53 cofactor 5.0
TBC1D25 TBC1 domain family, member 25 5.0
EPDR1 ependymin related 1 5.0
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 5.0
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 5.0
SZT2 seizure threshold 2 homolog (mouse) 5.0
SAR1B secretion associated, Ras related GTPase 1B 5.0
HLA-DMA major histocompatibility complex, class II, DM alpha 5.0
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 5.0
TSC2 tuberous sclerosis 2 5.0
ATXN3 ataxin 3 5.0
ITFG2 integrin alpha FG-GAP repeat containing 2 5.0
BCL10 B-cell CLL/lymphoma 10 5.0
TMEM9 transmembrane protein 9 5.0
GABARAPL2 GABA(A) receptor-associated protein-like 2 5.0
TRIP10 thyroid hormone receptor interactor 10 5.0
GPR137 G protein-coupled receptor 137 5.0
AP5M1 adaptor-related protein complex 5, mu 1 subunit 5.0
ARL8B ADP-ribosylation factor-like 8B 5.0
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 5.0
TFEB transcription factor EB 5.0
UBXN6 UBX domain protein 6 5.0
ACP5 acid phosphatase 5, tartrate resistant 5.0
DEPTOR DEP domain containing MTOR-interacting protein 5.0
HLA-DRA major histocompatibility complex, class II, DR alpha 5.0
PRSS16 protease, serine, 16 (thymus) 5.0
DEPDC5 DEP domain containing 5 5.0
STXBP2 syntaxin binding protein 2 5.0
RB1CC1 RB1-inducible coiled-coil 1 5.0
TFE3 transcription factor binding to IGHM enhancer 3 5.0
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 5.0
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 5.0
VPS33B vacuolar protein sorting 33 homolog B (yeast) 5.0
PIP4P2 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 5.0
STING1 stimulator of interferon response cGAMP interactor 1 5.0
SLC49A4 solute carrier family 49 member 4 5.0
RUBCNL rubicon like autophagy enhancer 5.0
MARCHF3 membrane associated ring-CH-type finger 3 5.0
MARCHF8 membrane associated ring-CH-type finger 8 5.0
SLC66A1 solute carrier family 66 member 1 5.0
SPAAR small regulatory polypeptide of amino acid response 5.0
MEAK7 MTOR associated protein, eak-7 homolog 5.0
PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 5.0
TBC1D7 TBC1 domain family, member 7 5.0
MFSD8 major facilitator superfamily domain containing 8 5.0
FCMR Fc fragment of IgM receptor 5.0
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 5.0
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 5.0
ATG5 autophagy related 5 5.0
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 5.0
HPS6 Hermansky-Pudlak syndrome 6 5.0
VMA12 vacuolar ATPase assembly factor VMA12 5.0
MAPKAP1 mitogen-activated protein kinase associated protein 1 5.0
HYAL3 hyaluronoglucosaminidase 3 5.0
RAB9A RAB9A, member RAS oncogene family 5.0
IFITM3 interferon induced transmembrane protein 3 5.0
IFITM1 interferon induced transmembrane protein 1 5.0
ZFYVE1 zinc finger, FYVE domain containing 1 5.0
MPEG1 macrophage expressed 1 5.0
LRRC8E leucine rich repeat containing 8 family, member E 5.0
LRRC8A leucine rich repeat containing 8 family, member A 5.0
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 5.0
CD1E CD1e molecule 5.0
CD1D CD1d molecule 5.0
HYAL2 hyaluronoglucosaminidase 2 5.0
GPR155 G protein-coupled receptor 155 5.0
MITF microphthalmia-associated transcription factor 5.0
TM4SF5 transmembrane 4 L six family member 5 5.0
BACE1 beta-site APP-cleaving enzyme 1 5.0
CD164 CD164 molecule, sialomucin 5.0
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 5.0
ADA adenosine deaminase 5.0
WDR81 WD repeat domain 81 5.0
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 5.0
FNBP1 formin binding protein 1 5.0
IFITM2 interferon induced transmembrane protein 2 5.0
TMEM9B TMEM9 domain family, member B 5.0
TMEM97 transmembrane protein 97 5.0
RRAGD Ras-related GTP binding D 5.0
RRAGA Ras-related GTP binding A 5.0
RRAGC Ras-related GTP binding C 5.0
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 5.0
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 5.0
CTBS chitobiase, di-N-acetyl- 5.0
VMA22 vacuolar ATPase assembly factor VMA22 5.0
MYO7A myosin VIIA 5.0
NAPSA napsin A aspartic peptidase 5.0
WIPI1 WD repeat domain, phosphoinositide interacting 1 5.0
SRC SRC proto-oncogene, non-receptor tyrosine kinase 5.0
SORT1 sortilin 1 5.0
RNF152 ring finger protein 152 5.0
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 5.0
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 5.0
ANXA11 annexin A11 5.0
SLC31A2 solute carrier family 31 (copper transporter), member 2 5.0
PLD3 phospholipase D family, member 3 5.0
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 5.0
HCK HCK proto-oncogene, Src family tyrosine kinase 5.0
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 5.0
OCA2 oculocutaneous albinism II 5.0
SLC38A9 solute carrier family 38, member 9 5.0
HLA-DMB major histocompatibility complex, class II, DM beta 5.0
SLC38A7 solute carrier family 38, member 7 5.0
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 5.0
RICTOR RPTOR independent companion of MTOR, complex 2 5.0
CTSH cathepsin H 5.0
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 5.0
AUP1 ancient ubiquitous protein 1 5.0
TYR tyrosinase 5.0
ATP10B ATPase, class V, type 10B 5.0
PRTN3 proteinase 3 5.0
TMBIM1 transmembrane BAX inhibitor motif containing 1 5.0
CDIP1 cell death-inducing p53 target 1 5.0
CHIT1 chitinase 1 (chitotriosidase) 5.0
NCOA4 nuclear receptor coactivator 4 5.0
SH3GLB1 SH3-domain GRB2-like endophilin B1 5.0
DEFA4 defensin, alpha 4, corticostatin 5.0
TMEM165 transmembrane protein 165 5.0
RAB27A RAB27A, member RAS oncogene family 5.0
VTI1B vesicle transport through interaction with t-SNAREs 1B 5.0
TECPR1 tectonin beta-propeller repeat containing 1 5.0
SIDT2 SID1 transmembrane family, member 2 5.0
SLC35F6 solute carrier family 35, member F6 5.0
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 5.0
LAPTM4A lysosomal protein transmembrane 4 alpha 5.0
HLA-F major histocompatibility complex, class I, F 5.0
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 5.0
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 5.0
GPR143 G protein-coupled receptor 143 5.0
CTSO cathepsin O 5.0
LAPTM4B lysosomal protein transmembrane 4 beta 5.0
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 5.0
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 4.0
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 4.0
RNF13 ring finger protein 13 4.0
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 4.0
PIGR polymeric immunoglobulin receptor 4.0
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 4.0
LAPTM5 lysosomal protein transmembrane 5 4.0
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 4.0
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 4.0
CYB5R3 cytochrome b5 reductase 3 4.0
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 4.0
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 4.0
CPPED1 calcineurin-like phosphoesterase domain containing 1 4.0
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 4.0
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 4.0
ORM2 orosomucoid 2 4.0
GPC6 glypican 6 4.0
TM6SF1 transmembrane 6 superfamily member 1 4.0
AP1B1 adaptor-related protein complex 1, beta 1 subunit 4.0
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 4.0
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 4.0
RAB44 RAB44, member RAS oncogene family 4.0
TOLLIP toll interacting protein 4.0
STOM stomatin 4.0
CHMP6 charged multivesicular body protein 6 4.0
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.0
WDR11 WD repeat domain 11 4.0
LGMN legumain 4.0
RRAGB Ras-related GTP binding B 4.0
GPC1 glypican 1 4.0
GPC2 glypican 2 4.0
ATP13A2 ATPase type 13A2 4.0
TOM1 target of myb1 (chicken) 4.0
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 4.0
ACR acrosin 4.0
FPR1 formyl peptide receptor 1 4.0
AHNAK AHNAK nucleoprotein 4.0
GPC5 glypican 5 4.0
GPC4 glypican 4 4.0
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 4.0
GPC3 glypican 3 4.0
CLTC clathrin, heavy chain (Hc) 4.0
CPNE1 copine I 4.0
NCAN neurocan 4.0
NCSTN nicastrin 4.0
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 4.0
RNF103-CHMP3 RNF103-CHMP3 readthrough 4.0
SCARB1 scavenger receptor class B, member 1 4.0
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 4.0
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 4.0
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 4.0
CTSB cathepsin B 4.0
CTSA cathepsin A 4.0
NCF2 neutrophil cytosolic factor 2 4.0
NCF1 neutrophil cytosolic factor 1 4.0
NCF4 neutrophil cytosolic factor 4, 40kDa 4.0
UNC13D unc-13 homolog D (C. elegans) 4.0
CTSL cathepsin L 4.0
RPTOR regulatory associated protein of MTOR, complex 1 4.0
CTSK cathepsin K 4.0
KPTN kaptin (actin binding protein) 4.0
RNF167 ring finger protein 167 4.0
AP3D1 adaptor-related protein complex 3, delta 1 subunit 4.0
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 4.0
CTSS cathepsin S 4.0
CTSZ cathepsin Z 4.0
AP1M2 adaptor-related protein complex 1, mu 2 subunit 4.0
AP1M1 adaptor-related protein complex 1, mu 1 subunit 4.0
OSBPL7 oxysterol binding protein-like 7 4.0
TUBB4B tubulin, beta 4B class IVb 4.0
CTSG cathepsin G 4.0
CTSF cathepsin F 4.0
CTSD cathepsin D 4.0
ACAN aggrecan 4.0
SQSTM1 sequestosome 1 4.0
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 4.0
RAB12 RAB12, member RAS oncogene family 4.0
RAB14 RAB14, member RAS oncogene family 4.0
SLC46A3 solute carrier family 46, member 3 4.0
STARD3NL STARD3 N-terminal like 4.0
ATP11C ATPase, class VI, type 11C 4.0
ATP11B ATPase, class VI, type 11B 4.0
ATP11A ATPase, class VI, type 11A 4.0
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 4.0
TMEM25 transmembrane protein 25 4.0
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 4.0
DEFA1B defensin, alpha 1B 4.0
IFI30 interferon, gamma-inducible protein 30 4.0
CALCOCO2 calcium binding and coiled-coil domain 2 4.0
TOM1L1 target of myb1 (chicken)-like 1 4.0
DCN decorin 4.0
ENPEP glutamyl aminopeptidase (aminopeptidase A) 4.0
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 4.0
TINAGL1 tubulointerstitial nephritis antigen-like 1 4.0
GAA glucosidase, alpha; acid 4.0
CPNE3 copine III 4.0
ADRB2 adrenoceptor beta 2, surface 4.0
PRELP proline/arginine-rich end leucine-rich repeat protein 4.0
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 4.0
PRMT1 protein arginine methyltransferase 1 4.0
PRICKLE1 prickle homolog 1 (Drosophila) 4.0
PCYOX1 prenylcysteine oxidase 1 4.0
EGFL7 EGF-like-domain, multiple 7 4.0
OSTM1 osteopetrosis associated transmembrane protein 1 4.0
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 4.0
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 4.0
MNDA myeloid cell nuclear differentiation antigen 4.0
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 4.0
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 4.0
LNPEP leucyl/cystinyl aminopeptidase 4.0
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 4.0
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 4.0
FMOD fibromodulin 4.0
SRGN serglycin 4.0
STX17 syntaxin 17 4.0
DPP4 dipeptidyl-peptidase 4 4.0
DPP7 dipeptidyl-peptidase 7 4.0
BCAN brevican 4.0
TMEM106B transmembrane protein 106B 4.0
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 4.0
HRNR hornerin 4.0
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 4.0
TRIM32 tripartite motif containing 32 4.0
NPC2 Niemann-Pick disease, type C2 4.0
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 4.0
RAB37 RAB37, member RAS oncogene family 4.0
RAB38 RAB38, member RAS oncogene family 4.0
RAB3D RAB3D, member RAS oncogene family 4.0
HSPA8 heat shock 70kDa protein 8 4.0
GC group-specific component (vitamin D binding protein) 4.0
TTR transthyretin 4.0
TMEM192 transmembrane protein 192 4.0
SLC48A1 solute carrier family 48 (heme transporter), member 1 4.0
GCA grancalcin, EF-hand calcium binding protein 4.0
NPC1 Niemann-Pick disease, type C1 4.0
SNAPIN SNAP-associated protein 4.0
VASN vasorin 4.0
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 4.0
GM2A GM2 ganglioside activator 4.0
HPS1 Hermansky-Pudlak syndrome 1 4.0
BORCS5 BLOC-1 related complex subunit 5 4.0
RMC1 regulator of MON1-CCZ1 4.0
MARCHF1 membrane associated ring-CH-type finger 1 4.0
BORCS8 BLOC-1 related complex subunit 8 4.0
ADA2 adenosine deaminase 2 4.0
MAGT1 magnesium transporter 1 4.0
PLAAT3 phospholipase A and acyltransferase 3 4.0
MYL11 myosin light chain 11 4.0
PLAAT1 phospholipase A and acyltransferase 1 4.0
PGAP6 post-GPI attachment to proteins 6 4.0
CBLIF cobalamin binding intrinsic factor 4.0
MINAR2 membrane integral NOTCH2 associated receptor 2 4.0
CHMP1B charged multivesicular body protein 1B 4.0
VMP1 vacuole membrane protein 1 4.0
ARHGAP45 Rho GTPase activating protein 45 4.0
CHMP7 charged multivesicular body protein 7 4.0
HPSE heparanase 4.0
C3AR1 complement component 3a receptor 1 4.0
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 4.0
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 4.0
USP6 ubiquitin specific peptidase 6 4.0
BGN biglycan 4.0
SFTPA2 surfactant protein A2 4.0
VCAN versican 4.0
SLC7A14 solute carrier family 7, member 14 4.0
BORCS6 BLOC-1 related complex subunit 6 4.0
BORCS7 BLOC-1 related complex subunit 7 4.0
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 4.0
CHMP5 charged multivesicular body protein 5 4.0
CLTA clathrin, light chain A 4.0
OCLN occludin 4.0
GUSB glucuronidase, beta 4.0
NSF N-ethylmaleimide-sensitive factor 4.0
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 4.0
NHLRC3 NHL repeat containing 3 4.0
TLR3 toll-like receptor 3 4.0
TLR7 toll-like receptor 7 4.0
TLR8 toll-like receptor 8 4.0
TLR9 toll-like receptor 9 4.0
PCSK9 proprotein convertase subtilisin/kexin type 9 4.0
PPT1 palmitoyl-protein thioesterase 1 4.0
PLA2G5 phospholipase A2, group V 4.0
ANKFY1 ankyrin repeat and FYVE domain containing 1 4.0
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 4.0
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 4.0
PRKCD protein kinase C, delta 4.0
FTL ferritin, light polypeptide 4.0
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 4.0
AP2M1 adaptor-related protein complex 2, mu 1 subunit 4.0
AGA aspartylglucosaminidase 4.0
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) 4.0
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 4.0
CYB561A3 cytochrome b561 family, member A3 4.0
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 4.0
LPCAT1 lysophosphatidylcholine acyltransferase 1 4.0
PA2G4 proliferation-associated 2G4, 38kDa 4.0
GDI2 GDP dissociation inhibitor 2 4.0
GLIPR1 GLI pathogenesis-related 1 4.0
DAGLB diacylglycerol lipase, beta 4.0
NAAA N-acylethanolamine acid amidase 4.0
VAT1 vesicle amine transport 1 4.0
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4.0
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4.0
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 4.0
ARL8A ADP-ribosylation factor-like 8A 4.0
GYG1 glycogenin 1 4.0
CSF3 colony stimulating factor 3 (granulocyte) 4.0
RNF183 ring finger protein 183 4.0
SYT12 synaptotagmin XII 4.0
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 4.0
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 4.0
GNS glucosamine (N-acetyl)-6-sulfatase 4.0
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 4.0
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 4.0
TEX264 testis expressed 264 4.0
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 4.0
MFSD1 major facilitator superfamily domain containing 1 4.0
CHMP4B charged multivesicular body protein 4B 4.0
CHMP4C charged multivesicular body protein 4C 4.0
STS steroid sulfatase (microsomal), isozyme S 4.0
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 4.0
HEBP2 heme binding protein 2 4.0
MYO6 myosin VI 4.0
EGF epidermal growth factor 4.0
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 4.0
IDS iduronate 2-sulfatase 4.0
C3 complement component 3 4.0
CP ceruloplasmin (ferroxidase) 4.0
AP3B1 adaptor-related protein complex 3, beta 1 subunit 4.0
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 4.0
STARD3 StAR-related lipid transfer (START) domain containing 3 4.0
SYT7 synaptotagmin VII 4.0
FRK fyn-related Src family tyrosine kinase 4.0
BST2 bone marrow stromal cell antigen 2 4.0
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 4.0
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 4.0
FLCN folliculin 4.0
ARRB1 arrestin, beta 1 4.0
SCGB1D1 secretoglobin, family 1D, member 1 4.0
RAB29 RAB29, member RAS oncogene family 4.0
SGSH N-sulfoglucosamine sulfohydrolase 4.0
PADI2 peptidyl arginine deiminase, type II 4.0
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 4.0
ANXA2 annexin A2 4.0
RAB5C RAB5C, member RAS oncogene family 4.0
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 4.0
PYGB phosphorylase, glycogen; brain 4.0
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 4.0
CHMP1A charged multivesicular body protein 1A 4.0
SAR1A secretion associated, Ras related GTPase 1A 4.0
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 4.0
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 4.0
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 4.0
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 4.0
NAPRT nicotinate phosphoribosyltransferase 4.0
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 4.0
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 4.0
LAMP1 lysosomal-associated membrane protein 1 4.0
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 4.0
TRPM2 transient receptor potential cation channel, subfamily M, member 2 4.0
IRGM immunity-related GTPase family, M 4.0
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 4.0
FAF2 Fas associated factor family member 2 4.0
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 4.0
TCN2 transcobalamin II 4.0
MANBA mannosidase, beta A, lysosomal 4.0
PRDX5 peroxiredoxin 5 4.0
CD34 CD34 molecule 4.0
OCIAD2 OCIA domain containing 2 4.0
RNASEK ribonuclease, RNase K 4.0
RNASE3 ribonuclease, RNase A family, 3 4.0
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 4.0
SDC1 syndecan 1 4.0
SDC2 syndecan 2 4.0
SDC3 syndecan 3 4.0
SDC4 syndecan 4 4.0
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 4.0
SESN2 sestrin 2 4.0
OCIAD1 OCIA domain containing 1 4.0
NAGLU N-acetylglucosaminidase, alpha 4.0
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 4.0
AZU1 azurocidin 1 4.0
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 4.0
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 4.0
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 4.0
MAPK1 mitogen-activated protein kinase 1 4.0
CLN3 ceroid-lipofuscinosis, neuronal 3 4.0
RAB7A RAB7A, member RAS oncogene family 4.0
ANPEP alanyl (membrane) aminopeptidase 4.0
PRCP prolylcarboxypeptidase (angiotensinase C) 4.0
ZNF395 zinc finger protein 395 4.0
PSEN1 presenilin 1 4.0
FLOT1 flotillin 1 4.0
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 4.0
VNN1 vanin 1 4.0
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 4.0
PRKD1 protein kinase D1 4.0
WDR41 WD repeat domain 41 4.0
ITM2C integral membrane protein 2C 4.0
ADAM8 ADAM metallopeptidase domain 8 4.0
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 4.0
RAP1B RAP1B, member of RAS oncogene family 4.0
LDLR low density lipoprotein receptor 4.0
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 4.0
SPG11 spastic paraplegia 11 (autosomal recessive) 4.0
CHMP2B charged multivesicular body protein 2B 4.0
CHMP2A charged multivesicular body protein 2A 4.0
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 4.0
KERA keratocan 4.0
TMEM179B transmembrane protein 179B 4.0
PRSS2 protease, serine, 2 (trypsin 2) 4.0
DSN1 DSN1, MIS12 kinetochore complex component 4.0
AP3M1 adaptor-related protein complex 3, mu 1 subunit 4.0
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 4.0
TBC1D14 TBC1 domain family, member 14 4.0
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 4.0
BPI bactericidal/permeability-increasing protein 4.0
PRKCSH protein kinase C substrate 80K-H 4.0
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 4.0
TUBB tubulin, beta class I 4.0
CST7 cystatin F (leukocystatin) 4.0
PTGES2 prostaglandin E synthase 2 4.0
PYCARD PYD and CARD domain containing 4.0
APOB apolipoprotein B 4.0
UNC93B1 unc-93 homolog B1 (C. elegans) 4.0
MFSD12 major facilitator superfamily domain containing 12 4.0
ACLY ATP citrate lyase 4.0
MGST1 microsomal glutathione S-transferase 1 4.0
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 4.0
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 4.0
CKAP4 cytoskeleton-associated protein 4 4.0
CREG1 cellular repressor of E1A-stimulated genes 1 4.0
AGRN agrin 4.0
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 4.0
TRIM23 tripartite motif containing 23 4.0
ABHD6 abhydrolase domain containing 6 4.0
CSF3R colony stimulating factor 3 receptor (granulocyte) 4.0
ELANE elastase, neutrophil expressed 4.0
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 4.0
CSPG4 chondroitin sulfate proteoglycan 4 4.0
ECE1 endothelin converting enzyme 1 4.0
STK11IP serine/threonine kinase 11 interacting protein 4.0
ACE angiotensin I converting enzyme 4.0
ACD adrenocortical dysplasia homolog (mouse) 4.0
CPQ carboxypeptidase Q 4.0
PLA2G4E phospholipase A2, group IVE 4.0
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 4.0
HSPG2 heparan sulfate proteoglycan 2 4.0
KXD1 KxDL motif containing 1 4.0
OMD osteomodulin 4.0
CHID1 chitinase domain containing 1 4.0
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 4.0
WDFY3 WD repeat and FYVE domain containing 3 4.0
LRP2 low density lipoprotein receptor-related protein 2 4.0
CCT2 chaperonin containing TCP1, subunit 2 (beta) 4.0
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 4.0
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 4.0
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 4.0
CUBN cubilin (intrinsic factor-cobalamin receptor) 4.0
SPNS1 spinster homolog 1 (Drosophila) 4.0
RAB2A RAB2A, member RAS oncogene family 4.0
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 4.0
TMEM79 transmembrane protein 79 4.0
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 4.0
NKG7 natural killer cell granule protein 7 4.0
IST1 increased sodium tolerance 1 homolog (yeast) 4.0
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 4.0
SLC44A2 solute carrier family 44 (choline transporter), member 2 4.0
C1D C1D nuclear receptor corepressor 4.0
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 4.0
IDUA iduronidase, alpha-L- 4.0
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 4.0
S100A7 S100 calcium binding protein A7 4.0
LUM lumican 4.0
CD63 CD63 molecule 4.0
STX3 syntaxin 3 4.0
STX4 syntaxin 4 4.0
STX7 syntaxin 7 4.0
AP5B1 adaptor-related protein complex 5, beta 1 subunit 4.0
TPCN1 two pore segment channel 1 4.0
CRHBP corticotropin releasing hormone binding protein 4.0
PLAC8 placenta-specific 8 4.0
LYN LYN proto-oncogene, Src family tyrosine kinase 4.0
SNAP29 synaptosomal-associated protein, 29kDa 4.0
CCT8 chaperonin containing TCP1, subunit 8 (theta) 4.0
SNX2 sorting nexin 2 4.0
SNX1 sorting nexin 1 4.0
SNX6 sorting nexin 6 4.0
FABP5 fatty acid binding protein 5 (psoriasis-associated) 4.0
NEU4 sialidase 4 4.0
LYZ lysozyme 4.0
RETN resistin 4.0
VAMP7 vesicle-associated membrane protein 7 4.0
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 4.0
SLCO4C1 solute carrier organic anion transporter family, member 4C1 4.0
SDCBP syndecan binding protein (syntenin) 4.0
DNASE2 deoxyribonuclease II, lysosomal 4.0
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 4.0
DEFA1 defensin, alpha 1 4.0
DEFA3 defensin, alpha 3, neutrophil-specific 4.0
ARSA arylsulfatase A 4.0
NFAM1 NFAT activating protein with ITAM motif 1 4.0
OGN osteoglycin 4.0
VAMP4 vesicle-associated membrane protein 4 4.0
CTSV cathepsin V 4.0
SPPL2A signal peptide peptidase like 2A 4.0
CLCN3 chloride channel, voltage-sensitive 3 4.0
CLCN6 chloride channel, voltage-sensitive 6 4.0
CLCN5 chloride channel, voltage-sensitive 5 4.0
GDAP2 ganglioside induced differentiation associated protein 2 4.0
CLCN7 chloride channel, voltage-sensitive 7 4.0
TRAPPC1 trafficking protein particle complex 1 4.0
LRRK2 leucine-rich repeat kinase 2 4.0
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 4.0
MPO myeloperoxidase 4.0
VCP valosin containing protein 4.0
COL6A1 collagen, type VI, alpha 1 4.0
ATG4B autophagy related 4B, cysteine peptidase 4.0
ZFYVE26 zinc finger, FYVE domain containing 26 4.0
PEG3 paternally expressed 3 4.0
GALNS galactosamine (N-acetyl)-6-sulfatase 4.0
GRN granulin 4.0
SPHK2 sphingosine kinase 2 4.0
SURF4 surfeit 4 4.0
VLDLR very low density lipoprotein receptor 4.0
RNASET2 ribonuclease T2 4.0
GOPC golgi-associated PDZ and coiled-coil motif containing 4.0
AP2B1 adaptor-related protein complex 2, beta 1 subunit 4.0
ANKRD44 ankyrin repeat domain 44 4.0
RAMP3 receptor (G protein-coupled) activity modifying protein 3 4.0
SYNGR1 synaptogyrin 1 4.0
RAMP2 receptor (G protein-coupled) activity modifying protein 2 4.0
TPCN2 two pore segment channel 2 4.0
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 4.0
PLA2G15 phospholipase A2, group XV 4.0
VTI1A vesicle transport through interaction with t-SNAREs 1A 4.0
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 4.0
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 4.0
HPS4 Hermansky-Pudlak syndrome 4 3.0
HEXA hexosaminidase A (alpha polypeptide) 3.0
SCARB2 scavenger receptor class B, member 2 3.0
SLC36A3 solute carrier family 36, member 3 3.0
GALC galactosylceramidase 3.0
GBA1 glucosylceramidase beta 1 3.0
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 3.0
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 3.0
ACP4 acid phosphatase 4 3.0
GLB1 galactosidase, beta 1 3.0
WASHC1 WASH complex subunit 1 3.0
LITAFD LITAF domain containing 3.0
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 3.0
CTSC cathepsin C 3.0
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 3.0
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 3.0
SIDT1 SID1 transmembrane family, member 1 3.0
ATG12 autophagy related 12 3.0
B2M beta-2-microglobulin 3.0
ACP3 acid phosphatase 3 3.0
LAMP2 lysosomal-associated membrane protein 2 3.0
ULK2 unc-51 like autophagy activating kinase 2 3.0
ULK3 unc-51 like kinase 3 3.0
HEXB hexosaminidase B (beta polypeptide) 3.0
TBC1D12 TBC1 domain family, member 12 3.0
CYBRD1 cytochrome b reductase 1 3.0
NEU3 sialidase 3 (membrane sialidase) 3.0
NEU2 sialidase 2 (cytosolic sialidase) 3.0
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3.0
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 3.0
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 3.0
ATG13 autophagy related 13 3.0
LARS1 leucyl-tRNA synthetase 1 3.0
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 3.0
GLB1L galactosidase, beta 1-like 3.0
HLA-DOA major histocompatibility complex, class II, DO alpha 3.0
VAC14 Vac14 homolog (S. cerevisiae) 3.0
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit 3.0
MAN2B1 mannosidase, alpha, class 2B, member 1 3.0
MAN2B2 mannosidase, alpha, class 2B, member 2 3.0
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 3.0
UVRAG UV radiation resistance associated 3.0
RAB9B RAB9B, member RAS oncogene family 3.0
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 3.0
FUCA2 fucosidase, alpha-L- 2, plasma 3.0
FUCA1 fucosidase, alpha-L- 1, tissue 3.0
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3.0
WDR24 WD repeat domain 24 3.0
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 3.0
GABARAPL1 GABA(A) receptor-associated protein like 1 3.0
HLA-DOB major histocompatibility complex, class II, DO beta 3.0
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 3.0
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 3.0
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 3.0
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.0
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 3.0
LAMP3 lysosomal-associated membrane protein 3 3.0
LAMP5 lysosomal-associated membrane protein family, member 5 3.0
MCOLN3 mucolipin 3 3.0
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 3.0
WDR59 WD repeat domain 59 3.0
ATG9B autophagy related 9B 3.0
ATG9A autophagy related 9A 3.0
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 3.0
PPT2 palmitoyl-protein thioesterase 2 3.0
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.0
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 3.0
GLB1L3 galactosidase, beta 1-like 3 3.0
GLB1L2 galactosidase, beta 1-like 2 3.0
SPPL2C signal peptide peptidase like 2C 3.0
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 3.0
CYB561 cytochrome b561 3.0
BECN1 beclin 1, autophagy related 3.0
CD68 CD68 molecule 3.0
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 3.0
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 3.0
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 3.0
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 3.0
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 3.0
RAB24 RAB24, member RAS oncogene family 3.0
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3.0
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 3.0
RNF19B ring finger protein 19B 3.0