| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.279037 |
| FBN1 | fibrillin 1 | 0.205916 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.157568 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.135973 |
| PLAT | plasminogen activator, tissue | 0.112761 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.103853 |
| COL1A2 | collagen, type I, alpha 2 | 0.0997567 |
| COL3A1 | collagen, type III, alpha 1 | 0.0837059 |
| LOXL2 | lysyl oxidase-like 2 | 0.0822902 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0780017 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.070337 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0679484 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0672371 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0669072 |
| B2M | beta-2-microglobulin | 0.0655464 |
| STC1 | stanniocalcin 1 | 0.0618631 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.061277 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0603424 |
| UBC | ubiquitin C | 0.0541601 |
| APP | amyloid beta (A4) precursor protein | 0.051354 |
| COL5A2 | collagen, type V, alpha 2 | 0.0508492 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0492403 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0478581 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.04679 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.043652 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0426684 |
| LOX | lysyl oxidase | 0.0423584 |
| GPC6 | glypican 6 | 0.0420764 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0407927 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0404818 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0388597 |
| THBS2 | thrombospondin 2 | 0.0383158 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0377187 |
| SBF2 | SET binding factor 2 | 0.0372277 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0367215 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0364981 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0359295 |
| YEATS2 | YEATS domain containing 2 | 0.0357166 |
| ATP13A3 | ATPase type 13A3 | 0.0354144 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0351873 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0347023 |
| CD99 | CD99 molecule | 0.0346644 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.034161 |
| VIM | vimentin | 0.0340061 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0335452 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0332528 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0325129 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0324935 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0321885 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0321214 |
| DST | dystonin | 0.0319993 |
| FRMD5 | FERM domain containing 5 | 0.0317759 |
| OGA | O-GlcNAcase | 0.0316607 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0312371 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0306049 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0299144 |
| TXNIP | thioredoxin interacting protein | 0.0298298 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.029799 |
| MT2A | metallothionein 2A | 0.0294512 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.02912 |
| MYADM | myeloid-associated differentiation marker | 0.0289037 |
| SERINC3 | serine incorporator 3 | 0.0287439 |
| NGLY1 | N-glycanase 1 | 0.0287359 |
| RAI14 | retinoic acid induced 14 | 0.0285355 |
| EXOC6B | exocyst complex component 6B | 0.0284519 |
| CCDC88A | coiled-coil domain containing 88A | 0.0283399 |
| CD44 | CD44 molecule (Indian blood group) | 0.0280262 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0279482 |
| OPTN | optineurin | 0.0278969 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0278814 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0278749 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0277622 |
| MT1X | metallothionein 1X | 0.0276535 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0274303 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0273823 |
| ZNF148 | zinc finger protein 148 | 0.0271589 |
| TPM3 | tropomyosin 3 | 0.0266991 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.026678 |
| PCGF5 | polycomb group ring finger 5 | 0.0265927 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0264161 |
| GLG1 | golgi glycoprotein 1 | 0.0261991 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0260567 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0258482 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0258467 |
| ANXA2 | annexin A2 | 0.0256367 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.025603 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0254896 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0254857 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0254046 |
| WASHC4 | WASH complex subunit 4 | 0.0251299 |
| XPO1 | exportin 1 | 0.0251147 |
| ANO6 | anoctamin 6 | 0.0250439 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0250386 |
| CALU | calumenin | 0.0245905 |
| CD109 | CD109 molecule | 0.0245356 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0243862 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0240898 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0239478 |
| HLA-E | major histocompatibility complex, class I, E | 0.0238637 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0238405 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A1 | collagen, type V, alpha 1 | -0.13946 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.137261 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115818 |
| CDH13 | cadherin 13 | -0.112664 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.106305 |
| PODXL | podocalyxin-like | -0.102743 |
| TMSB10 | thymosin beta 10 | -0.0772569 |
| FN1 | fibronectin 1 | -0.0760242 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0632537 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0592769 |
| POTEF | POTE ankyrin domain family, member F | -0.0541799 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0531885 |
| EGFR | epidermal growth factor receptor | -0.0530848 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0530302 |
| EFNA5 | ephrin-A5 | -0.0528674 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0504003 |
| LMNA | lamin A/C | -0.0502207 |
| S100A10 | S100 calcium binding protein A10 | -0.0502173 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0494133 |
| NDRG1 | N-myc downstream regulated 1 | -0.0478922 |
| RIGI | RNA sensor RIG-I | -0.0474707 |
| RUNX1 | runt-related transcription factor 1 | -0.0472572 |
| FLNA | filamin A, alpha | -0.0456136 |
| NAV1 | neuron navigator 1 | -0.0455436 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0451101 |
| RPL35A | ribosomal protein L35a | -0.0426 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0418451 |
| AHNAK | AHNAK nucleoprotein | -0.041484 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0396183 |
| HLA-B | major histocompatibility complex, class I, B | -0.03866 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0371691 |
| RRBP1 | ribosome binding protein 1 | -0.0354676 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0352273 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0347169 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0345915 |
| RPL23 | ribosomal protein L23 | -0.0345219 |
| SQSTM1 | sequestosome 1 | -0.0341342 |
| FSTL1 | follistatin-like 1 | -0.0335954 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0334686 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0330933 |
| CUX1 | cut-like homeobox 1 | -0.0328332 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0323421 |
| ACTG1 | actin gamma 1 | -0.031916 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0316204 |
| MAP1B | microtubule-associated protein 1B | -0.0316058 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0308724 |
| CYTH3 | cytohesin 3 | -0.0302428 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.029913 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0297427 |
| IL7R | interleukin 7 receptor | -0.0292229 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289951 |
| RPS8 | ribosomal protein S8 | -0.0289175 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0288246 |
| TLE4 | transducin-like enhancer of split 4 | -0.0286802 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0284583 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0282768 |
| RPS12 | ribosomal protein S12 | -0.0279066 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0276966 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0276918 |
| PLXNA2 | plexin A2 | -0.0276269 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0275643 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.026849 |
| DCLK2 | doublecortin-like kinase 2 | -0.026704 |
| GOLGB1 | golgin B1 | -0.0266514 |
| RPS24 | ribosomal protein S24 | -0.0262241 |
| RASAL2 | RAS protein activator like 2 | -0.0256875 |
| DENND1A | DENN/MADD domain containing 1A | -0.0255181 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0251226 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0250661 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0248969 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0246826 |
| PCDH7 | protocadherin 7 | -0.0244676 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.024405 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0243088 |
| SP100 | SP100 nuclear antigen | -0.024219 |
| RPL28 | ribosomal protein L28 | -0.0240703 |
| RPS3 | ribosomal protein S3 | -0.0240394 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0239343 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0238388 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0238088 |
| CCND1 | cyclin D1 | -0.0237043 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0234159 |
| HDAC9 | histone deacetylase 9 | -0.023266 |
| MSI2 | musashi RNA-binding protein 2 | -0.0231007 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0229892 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0229293 |
| INTS6 | integrator complex subunit 6 | -0.0227069 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.02256 |
| S100A6 | S100 calcium binding protein A6 | -0.0225057 |
| RPS19 | ribosomal protein S19 | -0.0224697 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0223942 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0222416 |
| MED13L | mediator complex subunit 13-like | -0.0221181 |
| IPO9 | importin 9 | -0.0219765 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0219231 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.021891 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.021885 |
| KIAA1549L | KIAA1549-like | -0.0217906 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0217814 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0217765 |
