| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0466682 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0391902 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0369183 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.035999 |
| ANXA1 | annexin A1 | 0.0350911 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0349278 |
| TNPO1 | transportin 1 | 0.0346719 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0305544 |
| NEK7 | NIMA-related kinase 7 | 0.0304873 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0301825 |
| LMO7 | LIM domain 7 | 0.0299857 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0295221 |
| OXR1 | oxidation resistance 1 | 0.0292498 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.028983 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0283505 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0268387 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0262727 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0261912 |
| RRM2 | ribonucleotide reductase M2 | 0.0254595 |
| NUP58 | nucleoporin 58 | 0.0246624 |
| ZNF292 | zinc finger protein 292 | 0.0244954 |
| VMP1 | vacuole membrane protein 1 | 0.0240299 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.023805 |
| AREG | amphiregulin | 0.0236698 |
| TRIM37 | tripartite motif containing 37 | 0.0236553 |
| CLDND1 | claudin domain containing 1 | 0.0235437 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.022896 |
| GASK1B | golgi associated kinase 1B | 0.0227971 |
| PRKCI | protein kinase C, iota | 0.0225939 |
| ECT2 | epithelial cell transforming 2 | 0.0217595 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0207641 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0207263 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0206926 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0206511 |
| CPOX | coproporphyrinogen oxidase | 0.0206504 |
| EPHA5 | EPH receptor A5 | 0.0205883 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0204786 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0199874 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0196676 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0194981 |
| CISD1 | CDGSH iron sulfur domain 1 | 0.0192035 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0191251 |
| EML6 | echinoderm microtubule associated protein like 6 | 0.0189348 |
| IPMK | inositol polyphosphate multikinase | 0.0188113 |
| THOC1 | THO complex 1 | 0.0187649 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0182795 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0180517 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0176601 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0176103 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0175339 |
| CDK19 | cyclin-dependent kinase 19 | 0.0174495 |
| LYPLA1 | lysophospholipase I | 0.0173127 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0171462 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0170223 |
| DCP2 | decapping mRNA 2 | 0.0169519 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0168623 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0164822 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.0163814 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.016241 |
| CHD8 | chromodomain helicase DNA binding protein 8 | 0.0161179 |
| ZNF217 | zinc finger protein 217 | 0.0160991 |
| FANCL | Fanconi anemia, complementation group L | 0.0158201 |
| RLIM | ring finger protein, LIM domain interacting | 0.0157369 |
| SFTPA2 | surfactant protein A2 | 0.0155625 |
| SERINC1 | serine incorporator 1 | 0.015444 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0154397 |
| LEMD3 | LEM domain containing 3 | 0.0152305 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0152091 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0151527 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0151255 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.015083 |
| CD164 | CD164 molecule, sialomucin | 0.0150252 |
| CEP57 | centrosomal protein 57kDa | 0.0148361 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.014796 |
| TTC21B | tetratricopeptide repeat domain 21B | 0.0147901 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0147085 |
| MORF4L1 | mortality factor 4 like 1 | 0.014697 |
| HLTF | helicase-like transcription factor | 0.0145193 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0145129 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0142739 |
| PTEN | phosphatase and tensin homolog | 0.0142566 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0142224 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0142164 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.014194 |
| SETD5 | SET domain containing 5 | 0.0140326 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0140217 |
| KIAA1958 | KIAA1958 | 0.0139922 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0139824 |
| RBM27 | RNA binding motif protein 27 | 0.0138767 |
| NEMF | nuclear export mediator factor | 0.01386 |
| MICU3 | mitochondrial calcium uptake family, member 3 | 0.0136954 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0136752 |
| WDR11 | WD repeat domain 11 | 0.0136208 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0135779 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0135227 |
| CEP192 | centrosomal protein 192kDa | 0.0134985 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0134883 |
| NHSL1 | NHS-like 1 | 0.0134786 |
| COG5 | component of oligomeric golgi complex 5 | 0.0134697 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0133522 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.235108 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.140846 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115783 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0905096 |
| VIM | vimentin | -0.0841369 |
| ACTG1 | actin gamma 1 | -0.0823905 |
| PCDH7 | protocadherin 7 | -0.0805628 |
| HMGA2 | high mobility group AT-hook 2 | -0.0770636 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0738789 |
| TMSB10 | thymosin beta 10 | -0.0735422 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0682933 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0627893 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0601435 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0571189 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0570518 |
| RPS19 | ribosomal protein S19 | -0.0557837 |
| JMJD1C | jumonji domain containing 1C | -0.055362 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0545385 |
| RPS8 | ribosomal protein S8 | -0.0524983 |
| RPS6 | ribosomal protein S6 | -0.0519321 |
| YAP1 | Yes-associated protein 1 | -0.0497259 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0491073 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.046447 |
| PTMA | prothymosin, alpha | -0.0458015 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0449207 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0445329 |
| RPL23 | ribosomal protein L23 | -0.0438976 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0406075 |
| MGAT4C | MGAT4 family, member C | -0.0405625 |
| YBX3 | Y box binding protein 3 | -0.0396296 |
| EGR1 | early growth response 1 | -0.0394601 |
| RPL35A | ribosomal protein L35a | -0.0380881 |
| HMGA1 | high mobility group AT-hook 1 | -0.0369669 |
| RPL34 | ribosomal protein L34 | -0.0368167 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0367298 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0349512 |
| FNDC3B | fibronectin type III domain containing 3B | -0.034331 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0342605 |
| TXNRD1 | thioredoxin reductase 1 | -0.0340542 |
| ADIPOR2 | adiponectin receptor 2 | -0.0336656 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0330546 |
| NEBL | nebulette | -0.0321255 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0320792 |
| CENPF | centromere protein F, 350/400kDa | -0.0318384 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0315756 |
| HLA-A | major histocompatibility complex, class I, A | -0.0312415 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0297563 |
| HMGB1 | high mobility group box 1 | -0.0292531 |
| RPLP1 | ribosomal protein, large, P1 | -0.0290248 |
| RASAL2 | RAS protein activator like 2 | -0.0290002 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0289483 |
| TBCA | tubulin folding cofactor A | -0.0286961 |
| YBX1 | Y box binding protein 1 | -0.0285512 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0284466 |
| RPS27 | ribosomal protein S27 | -0.0282125 |
| FTL | ferritin, light polypeptide | -0.0276581 |
| RPL11 | ribosomal protein L11 | -0.0275602 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0275288 |
| RHOA | ras homolog family member A | -0.0273667 |
| CMIP | c-Maf inducing protein | -0.0270026 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0269818 |
| RBM39 | RNA binding motif protein 39 | -0.0269357 |
| RPL19 | ribosomal protein L19 | -0.0266572 |
| MKI67 | marker of proliferation Ki-67 | -0.0261051 |
| TUBA1B | tubulin, alpha 1b | -0.0259937 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0258018 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0256174 |
| RAB10 | RAB10, member RAS oncogene family | -0.0253188 |
| POTEF | POTE ankyrin domain family, member F | -0.0253029 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.0252395 |
| ZNF638 | zinc finger protein 638 | -0.0251971 |
| ERBIN | erbb2 interacting protein | -0.0250882 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0250741 |
| RPS12 | ribosomal protein S12 | -0.0249006 |
| S100A11 | S100 calcium binding protein A11 | -0.0248942 |
| TMEM123 | transmembrane protein 123 | -0.0243933 |
| RPL12 | ribosomal protein L12 | -0.0242497 |
| RPS20 | ribosomal protein S20 | -0.0242023 |
| EDARADD | EDAR-associated death domain | -0.0241857 |
| RPL37A | ribosomal protein L37a | -0.0239764 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.02397 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0238167 |
| RPL9 | ribosomal protein L9 | -0.0237299 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0233598 |
| CDK6 | cyclin-dependent kinase 6 | -0.0233319 |
| S100A10 | S100 calcium binding protein A10 | -0.0233211 |
| RPL37 | ribosomal protein L37 | -0.0232363 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0230619 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.023006 |
| CCN2 | cellular communication network factor 2 | -0.0229158 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0228623 |
| CCDC88A | coiled-coil domain containing 88A | -0.0228384 |
| NUP98 | nucleoporin 98kDa | -0.0227902 |
| MAP1B | microtubule-associated protein 1B | -0.0227838 |
| INTS6 | integrator complex subunit 6 | -0.0227299 |
| RPS16 | ribosomal protein S16 | -0.0226991 |
| RPL5 | ribosomal protein L5 | -0.0226374 |
| RPL28 | ribosomal protein L28 | -0.0225126 |
| CANX | calnexin | -0.0223909 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0223648 |
