| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.106527 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0831081 |
| SYT1 | synaptotagmin I | 0.0665956 |
| FAM13A | family with sequence similarity 13, member A | 0.0662667 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0652868 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0601639 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0586872 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0564087 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0563112 |
| DST | dystonin | 0.0559169 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0531317 |
| CANX | calnexin | 0.0522497 |
| DPH6 | diphthamine biosynthesis 6 | 0.0516185 |
| PLAT | plasminogen activator, tissue | 0.0509443 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0508105 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0504766 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0495553 |
| DTNA | dystrobrevin, alpha | 0.0484717 |
| SEPTIN9 | septin 9 | 0.0482638 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0461375 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0461188 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0439301 |
| EPHA3 | EPH receptor A3 | 0.0414808 |
| PGK1 | phosphoglycerate kinase 1 | 0.0403376 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0394796 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0385 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0380401 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0378465 |
| CALU | calumenin | 0.0374086 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0372017 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0365968 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.036245 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0360838 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0342134 |
| PKM | pyruvate kinase, muscle | 0.0340362 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0328611 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0325385 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0322554 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0321734 |
| MYO9A | myosin IXA | 0.031843 |
| ARRDC3 | arrestin domain containing 3 | 0.0317482 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0316596 |
| CADM2 | cell adhesion molecule 2 | 0.031379 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0313204 |
| ANGPT1 | angiopoietin 1 | 0.0310925 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0308429 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0303922 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0303241 |
| MEIS2 | Meis homeobox 2 | 0.0297744 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0296471 |
| PTK2 | protein tyrosine kinase 2 | 0.0296248 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.029365 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0293322 |
| HMGA2 | high mobility group AT-hook 2 | 0.0293147 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0292236 |
| ENO1 | enolase 1, (alpha) | 0.0287774 |
| RTN4 | reticulon 4 | 0.02859 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.028464 |
| NUP58 | nucleoporin 58 | 0.0281764 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0280716 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0274474 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0274204 |
| HELZ | helicase with zinc finger | 0.0274004 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0273708 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0271 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0270384 |
| STAC | SH3 and cysteine rich domain | 0.0269352 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0266417 |
| SNX13 | sorting nexin 13 | 0.0265332 |
| NBAS | neuroblastoma amplified sequence | 0.0264175 |
| SCG2 | secretogranin II | 0.0263475 |
| ZNF148 | zinc finger protein 148 | 0.0262615 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0262487 |
| AQR | aquarius intron-binding spliceosomal factor | 0.0261365 |
| AHR | aryl hydrocarbon receptor | 0.0260685 |
| VEGFA | vascular endothelial growth factor A | 0.0256703 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0254449 |
| SPAG9 | sperm associated antigen 9 | 0.0254391 |
| CADM1 | cell adhesion molecule 1 | 0.0253624 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0252988 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0251824 |
| NDRG1 | N-myc downstream regulated 1 | 0.0251333 |
| ANK2 | ankyrin 2, neuronal | 0.0250056 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0248384 |
| FAM162A | family with sequence similarity 162, member A | 0.0247208 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0244405 |
| ERGIC2 | ERGIC and golgi 2 | 0.0242224 |
| JMJD1C | jumonji domain containing 1C | 0.0241898 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0241615 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0241319 |
| GPC5 | glypican 5 | 0.0240303 |
| VMP1 | vacuole membrane protein 1 | 0.0239813 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0239687 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.02363 |
| CDK19 | cyclin-dependent kinase 19 | 0.0234101 |
| DIAPH2 | diaphanous-related formin 2 | 0.0232403 |
| MEF2A | myocyte enhancer factor 2A | 0.0231365 |
| MMP12 | matrix metallopeptidase 12 | 0.0231177 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0230015 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0229724 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.258802 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.18201 |
| VCL | vinculin | -0.103974 |
| LSAMP | limbic system-associated membrane protein | -0.0786927 |
| RPL19 | ribosomal protein L19 | -0.0582858 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0530755 |
| TRIB2 | tribbles pseudokinase 2 | -0.0513957 |
| RPL34 | ribosomal protein L34 | -0.0505891 |
| RPL38 | ribosomal protein L38 | -0.0489392 |
| RPL23 | ribosomal protein L23 | -0.0487255 |
| PTMA | prothymosin, alpha | -0.048127 |
| EGR1 | early growth response 1 | -0.0477898 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0474421 |
| ACTG1 | actin gamma 1 | -0.0471555 |
| TMSB10 | thymosin beta 10 | -0.0449749 |
| GNAS | GNAS complex locus | -0.0428696 |
| RPLP1 | ribosomal protein, large, P1 | -0.0413052 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.038862 |
| TPM4 | tropomyosin 4 | -0.0377035 |
| VIM | vimentin | -0.0374513 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0373555 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0372881 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0367877 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.035267 |
| RPL35A | ribosomal protein L35a | -0.0349156 |
| CALD1 | caldesmon 1 | -0.0339085 |
| FBXO11 | F-box protein 11 | -0.0330427 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0327199 |
| THBS1 | thrombospondin 1 | -0.0326052 |
| GLCCI1 | glucocorticoid induced 1 | -0.0324575 |
| S100A6 | S100 calcium binding protein A6 | -0.0323781 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0322168 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0312196 |
| IER3 | immediate early response 3 | -0.0309493 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0306879 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0303828 |
| GPATCH8 | G patch domain containing 8 | -0.0301855 |
| RPS16 | ribosomal protein S16 | -0.0301373 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0298168 |
| FTL | ferritin, light polypeptide | -0.0290414 |
| RPL27 | ribosomal protein L27 | -0.0288269 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0283476 |
| RPL13A | ribosomal protein L13a | -0.0279571 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.027898 |
| ZNF33B | zinc finger protein 33B | -0.0274037 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0273253 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0271611 |
| SQSTM1 | sequestosome 1 | -0.0270345 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0267851 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0267632 |
| RIGI | RNA sensor RIG-I | -0.0267026 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0262104 |
| PDE10A | phosphodiesterase 10A | -0.0260245 |
| RPS24 | ribosomal protein S24 | -0.0258934 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0253756 |
| RPS3 | ribosomal protein S3 | -0.0251585 |
| GPHN | gephyrin | -0.0249158 |
| AUTS2 | autism susceptibility candidate 2 | -0.0248713 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0248294 |
| TPM1 | tropomyosin 1 (alpha) | -0.0244468 |
| SEPTIN2 | septin 2 | -0.0243337 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0240233 |
| NUB1 | negative regulator of ubiquitin-like proteins 1 | -0.0240118 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0237746 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.023705 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0235802 |
| DSTN | destrin (actin depolymerizing factor) | -0.0235786 |
| LMNA | lamin A/C | -0.0234166 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0233789 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | -0.0233764 |
| DISP1 | dispatched homolog 1 (Drosophila) | -0.0231982 |
| CUL3 | cullin 3 | -0.0231873 |
| ZNF207 | zinc finger protein 207 | -0.0231388 |
| RPL39 | ribosomal protein L39 | -0.0231097 |
| FUS | FUS RNA binding protein | -0.0230843 |
| INO80 | INO80 complex subunit | -0.0229754 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0226969 |
| MED13 | mediator complex subunit 13 | -0.0226524 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0225688 |
| RPLP2 | ribosomal protein, large, P2 | -0.0221844 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | -0.0219703 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0216704 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0214948 |
| RPL36 | ribosomal protein L36 | -0.0214619 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0214555 |
| RPS27A | ribosomal protein S27a | -0.0211688 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0209392 |
| CFDP1 | craniofacial development protein 1 | -0.0207231 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.020699 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0206457 |
| MYO6 | myosin VI | -0.0205645 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0204719 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0204506 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0204028 |
| H1-0 | H1.0 linker histone | -0.0203048 |
| RPL28 | ribosomal protein L28 | -0.0202809 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0201601 |
| FAM107B | family with sequence similarity 107, member B | -0.0200774 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0200508 |
| MBTD1 | mbt domain containing 1 | -0.0198404 |
