| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.0902379 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0619352 |
| RNF149 | ring finger protein 149 | 0.0561517 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0553986 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0500971 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0496386 |
| CANX | calnexin | 0.0461743 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.042648 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0414145 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0406169 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0392452 |
| STK24 | serine/threonine kinase 24 | 0.039094 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0382272 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0379485 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0363012 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0359638 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0350317 |
| PGK1 | phosphoglycerate kinase 1 | 0.0347722 |
| COG6 | component of oligomeric golgi complex 6 | 0.034352 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0339594 |
| NCOA2 | nuclear receptor coactivator 2 | 0.033356 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.033266 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0325808 |
| EHBP1 | EH domain binding protein 1 | 0.0310472 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0303267 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0296382 |
| IFNGR1 | interferon gamma receptor 1 | 0.0296226 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0291167 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0288822 |
| DSPP | dentin sialophosphoprotein | 0.0288353 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.028435 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0283802 |
| ENO1 | enolase 1, (alpha) | 0.0283435 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0282377 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0282228 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0282023 |
| MLPH | melanophilin | 0.0279211 |
| KIF16B | kinesin family member 16B | 0.0277201 |
| DENND4C | DENN/MADD domain containing 4C | 0.027234 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0272056 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0269553 |
| MEF2A | myocyte enhancer factor 2A | 0.0263898 |
| COPA | coatomer protein complex, subunit alpha | 0.0258909 |
| TAOK3 | TAO kinase 3 | 0.0258648 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0255431 |
| FRYL | FRY-like | 0.0248758 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0246476 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0239956 |
| TMEM245 | transmembrane protein 245 | 0.0239951 |
| KLHL24 | kelch-like family member 24 | 0.0236776 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0232414 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0230805 |
| GOLPH3L | golgi phosphoprotein 3-like | 0.023052 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0228823 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0228032 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0227808 |
| ZNF638 | zinc finger protein 638 | 0.0227042 |
| ZNF395 | zinc finger protein 395 | 0.0226535 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0226033 |
| PTEN | phosphatase and tensin homolog | 0.0225955 |
| ARRDC3 | arrestin domain containing 3 | 0.0225916 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.022579 |
| AHI1 | Abelson helper integration site 1 | 0.0224468 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0222667 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0222008 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0221845 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0221649 |
| SP3 | Sp3 transcription factor | 0.0221516 |
| MEIS2 | Meis homeobox 2 | 0.0219022 |
| FDPS | farnesyl diphosphate synthase | 0.0218717 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0217925 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0216726 |
| MATR3 | matrin 3 | 0.0215273 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0214908 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0214148 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0212959 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0212388 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0210983 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0209321 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.020887 |
| PRKCA | protein kinase C, alpha | 0.0208532 |
| FANCI | Fanconi anemia, complementation group I | 0.0208262 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0207007 |
| MED13 | mediator complex subunit 13 | 0.0205163 |
| YY1 | YY1 transcription factor | 0.0204034 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0203409 |
| USP54 | ubiquitin specific peptidase 54 | 0.020083 |
| RAD51B | RAD51 paralog B | 0.0197828 |
| ZNF609 | zinc finger protein 609 | 0.0197012 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0196021 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0195954 |
| LIMA1 | LIM domain and actin binding 1 | 0.0195503 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0195298 |
| PCM1 | pericentriolar material 1 | 0.0195287 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.019508 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0194893 |
| USP8 | ubiquitin specific peptidase 8 | 0.0194702 |
| FBXO34 | F-box protein 34 | 0.0194313 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0193928 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0193551 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.200808 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.100144 |
| EZR | ezrin | -0.0874865 |
| ANXA2 | annexin A2 | -0.0798846 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.074958 |
| EGR1 | early growth response 1 | -0.070587 |
| SQSTM1 | sequestosome 1 | -0.0699269 |
| RIGI | RNA sensor RIG-I | -0.0684941 |
| PLSCR1 | phospholipid scramblase 1 | -0.0634636 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0591753 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0566546 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0557791 |
| B2M | beta-2-microglobulin | -0.0546901 |
| INTS6 | integrator complex subunit 6 | -0.0546263 |
| SPATA13 | spermatogenesis associated 13 | -0.0526995 |
| RRBP1 | ribosome binding protein 1 | -0.0518132 |
| MYO1E | myosin IE | -0.050615 |
| IRS2 | insulin receptor substrate 2 | -0.0500414 |
| PERP | PERP, TP53 apoptosis effector | -0.0493697 |
| ZNF292 | zinc finger protein 292 | -0.0476627 |
| RNF213 | ring finger protein 213 | -0.0459945 |
| IRF1 | interferon regulatory factor 1 | -0.0459272 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0458189 |
| LCN2 | lipocalin 2 | -0.0457291 |
| EPHB2 | EPH receptor B2 | -0.0456318 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0456082 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0448321 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0440231 |
| RUNX1 | runt-related transcription factor 1 | -0.0431425 |
| MX1 | MX dynamin-like GTPase 1 | -0.0423312 |
| HLA-B | major histocompatibility complex, class I, B | -0.0423297 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0414283 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0407052 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0394469 |
| SDC4 | syndecan 4 | -0.0392181 |
| MX2 | MX dynamin-like GTPase 2 | -0.0381444 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0375756 |
| TMSB10 | thymosin beta 10 | -0.037134 |
| VCL | vinculin | -0.0370797 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.036579 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.03645 |
| ANXA1 | annexin A1 | -0.0359557 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0358149 |
| TMC5 | transmembrane channel-like 5 | -0.0348588 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.034822 |
| ATP11A | ATPase, class VI, type 11A | -0.034125 |
| TNS4 | tensin 4 | -0.0339969 |
| JUN | jun proto-oncogene | -0.0339211 |
| DUSP10 | dual specificity phosphatase 10 | -0.0335657 |
| SP100 | SP100 nuclear antigen | -0.0335536 |
| HLA-C | major histocompatibility complex, class I, C | -0.0332388 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0330573 |
| H1-0 | H1.0 linker histone | -0.0321747 |
| EFNB2 | ephrin-B2 | -0.0321112 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0319415 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0315884 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0311832 |
| ERBIN | erbb2 interacting protein | -0.0307367 |
| HM13 | histocompatibility (minor) 13 | -0.0305055 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0304537 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0300011 |
| MORF4L2 | mortality factor 4 like 2 | -0.0298663 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0296031 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0292629 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0291108 |
| PMP22 | peripheral myelin protein 22 | -0.0280845 |
| RPL23 | ribosomal protein L23 | -0.0280424 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0279044 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0278808 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0269843 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0268475 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0264617 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0263621 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0257881 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0257757 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0256093 |
| FNIP2 | folliculin interacting protein 2 | -0.0255929 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0255328 |
| ACTG1 | actin gamma 1 | -0.0250004 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0246225 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0244279 |
| SLC38A2 | solute carrier family 38, member 2 | -0.024158 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0241462 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0240922 |
| SMAD3 | SMAD family member 3 | -0.0239712 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0238718 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0237599 |
| FUS | FUS RNA binding protein | -0.0237003 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0235826 |
| SERINC5 | serine incorporator 5 | -0.023296 |
| GOLGB1 | golgin B1 | -0.0230589 |
| HDAC4 | histone deacetylase 4 | -0.022801 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.022706 |
| LMNA | lamin A/C | -0.0226978 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0225849 |
| ZNF165 | zinc finger protein 165 | -0.0221475 |
| KIAA1217 | KIAA1217 | -0.0219885 |
| TC2N | tandem C2 domains, nuclear | -0.0219322 |
| FHL2 | four and a half LIM domains 2 | -0.0216464 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0213605 |
