| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Valdecoxib_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.157112 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.134173 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.10005 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0876192 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0862797 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0850234 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0844286 |
| STC1 | stanniocalcin 1 | 0.0829611 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0777315 |
| LOX | lysyl oxidase | 0.0565097 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.053237 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0516444 |
| CALU | calumenin | 0.0495779 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0488635 |
| ARRDC3 | arrestin domain containing 3 | 0.0485746 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0480987 |
| NAV2 | neuron navigator 2 | 0.0478367 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0472737 |
| CLIC4 | chloride intracellular channel 4 | 0.0472097 |
| PTMA | prothymosin, alpha | 0.0471859 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0464912 |
| TPM4 | tropomyosin 4 | 0.0458764 |
| CADM1 | cell adhesion molecule 1 | 0.0447071 |
| CANX | calnexin | 0.0438772 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0430185 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0391726 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0379868 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.037635 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0375097 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0362799 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0352099 |
| FBN1 | fibrillin 1 | 0.0347852 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0338887 |
| SPAG9 | sperm associated antigen 9 | 0.0334528 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.032276 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0316536 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0311637 |
| APP | amyloid beta (A4) precursor protein | 0.0309353 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0309182 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0302755 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.030136 |
| CDC27 | cell division cycle 27 | 0.0299092 |
| TPX2 | TPX2, microtubule-associated | 0.0298216 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0295918 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0295396 |
| TPR | translocated promoter region, nuclear basket protein | 0.0289545 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0285717 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0284946 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.028222 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0281604 |
| HMGB2 | high mobility group box 2 | 0.0279623 |
| NKTR | natural killer cell triggering receptor | 0.0276065 |
| ZNF292 | zinc finger protein 292 | 0.0275379 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0274169 |
| ANXA5 | annexin A5 | 0.0273557 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0272693 |
| CENPF | centromere protein F, 350/400kDa | 0.0270078 |
| FAM20C | family with sequence similarity 20, member C | 0.0265515 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0262946 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0259882 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0259838 |
| POSTN | periostin, osteoblast specific factor | 0.0258508 |
| MORF4L2 | mortality factor 4 like 2 | 0.0258405 |
| TMF1 | TATA element modulatory factor 1 | 0.02553 |
| LDHA | lactate dehydrogenase A | 0.0255216 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0254275 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0252899 |
| CEP350 | centrosomal protein 350kDa | 0.0251461 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0251347 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.025062 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0250198 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0247317 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0246838 |
| SQLE | squalene epoxidase | 0.0245636 |
| SRP54 | signal recognition particle 54kDa | 0.0243116 |
| ARF4 | ADP-ribosylation factor 4 | 0.0242968 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0242886 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0241538 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0239584 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0238992 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0238927 |
| CENPE | centromere protein E, 312kDa | 0.0238302 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0236037 |
| QKI | QKI, KH domain containing, RNA binding | 0.0235437 |
| SUCO | SUN domain containing ossification factor | 0.0234665 |
| PDE8A | phosphodiesterase 8A | 0.0232588 |
| INSIG2 | insulin induced gene 2 | 0.0232235 |
| DSPP | dentin sialophosphoprotein | 0.0231336 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0230201 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0229725 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0228329 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0227424 |
| HDLBP | high density lipoprotein binding protein | 0.0224907 |
| ANLN | anillin, actin binding protein | 0.0224556 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0224542 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0224516 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0224117 |
| FRYL | FRY-like | 0.0223093 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0220136 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0219064 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.308099 |
| COL1A1 | collagen, type I, alpha 1 | -0.141763 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.140699 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116347 |
| NDRG1 | N-myc downstream regulated 1 | -0.0975655 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0951717 |
| TMSB10 | thymosin beta 10 | -0.0933625 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0928311 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0680356 |
| CALD1 | caldesmon 1 | -0.0654887 |
| COL5A1 | collagen, type V, alpha 1 | -0.0616873 |
| VIM | vimentin | -0.0615066 |
| CDH13 | cadherin 13 | -0.0609067 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0600306 |
| CD44 | CD44 molecule (Indian blood group) | -0.059603 |
| GLIS3 | GLIS family zinc finger 3 | -0.0582606 |
| COL1A2 | collagen, type I, alpha 2 | -0.0553543 |
| ACTG1 | actin gamma 1 | -0.0525074 |
| CNTN5 | contactin 5 | -0.0514027 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0480526 |
| MT2A | metallothionein 2A | -0.0474688 |
| EXT1 | exostosin glycosyltransferase 1 | -0.047041 |
| RPS8 | ribosomal protein S8 | -0.0437595 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0433132 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0430912 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0414448 |
| PTK2 | protein tyrosine kinase 2 | -0.0410021 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0406083 |
| OSMR | oncostatin M receptor | -0.0404415 |
| EGFR | epidermal growth factor receptor | -0.0401099 |
| PDE10A | phosphodiesterase 10A | -0.0389522 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0383176 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0376965 |
| NAV1 | neuron navigator 1 | -0.0373126 |
| RUNX1 | runt-related transcription factor 1 | -0.0364709 |
| S100A9 | S100 calcium binding protein A9 | -0.0361243 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0351797 |
| COL6A1 | collagen, type VI, alpha 1 | -0.033545 |
| FOXP1 | forkhead box P1 | -0.0329317 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0328564 |
| RPL23 | ribosomal protein L23 | -0.0322533 |
| RPL35A | ribosomal protein L35a | -0.0321897 |
| ASPH | aspartate beta-hydroxylase | -0.032101 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0319958 |
| TPM1 | tropomyosin 1 (alpha) | -0.0319607 |
| PLEC | plectin | -0.0297456 |
| CTSB | cathepsin B | -0.0293528 |
| RPL26 | ribosomal protein L26 | -0.0292975 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0291671 |
| EGR1 | early growth response 1 | -0.0288998 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0287706 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0286179 |
| RPS2 | ribosomal protein S2 | -0.0283404 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0269651 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0269563 |
| NEK10 | NIMA-related kinase 10 | -0.0266129 |
| RPL28 | ribosomal protein L28 | -0.0263736 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0261466 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0257209 |
| RPS25 | ribosomal protein S25 | -0.0256168 |
| RPL11 | ribosomal protein L11 | -0.0253598 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0253276 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0251825 |
| SVIL | supervillin | -0.0251482 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0251236 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0249939 |
| JAG1 | jagged 1 | -0.0249431 |
| IL6ST | interleukin 6 signal transducer | -0.0247428 |
| HMCN1 | hemicentin 1 | -0.0247031 |
| RPL7 | ribosomal protein L7 | -0.0245996 |
| RPL5 | ribosomal protein L5 | -0.0245099 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0244125 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0242629 |
| NREP | neuronal regeneration related protein | -0.0241279 |
| NRP1 | neuropilin 1 | -0.0240689 |
| RPS6 | ribosomal protein S6 | -0.0238882 |
| EHD2 | EH-domain containing 2 | -0.0237798 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0235822 |
| PFN1 | profilin 1 | -0.0234978 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0233417 |
| RPS20 | ribosomal protein S20 | -0.0226352 |
| VEGFC | vascular endothelial growth factor C | -0.0223463 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0222849 |
| RPS21 | ribosomal protein S21 | -0.0221767 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0220667 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0216101 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0216018 |
| TENM3 | teneurin transmembrane protein 3 | -0.0215173 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0214872 |
| ITGA11 | integrin, alpha 11 | -0.0212256 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0212118 |
| NAV3 | neuron navigator 3 | -0.0211176 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.021111 |
| RPL36 | ribosomal protein L36 | -0.0210385 |
| CUX1 | cut-like homeobox 1 | -0.0209437 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0208212 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0207339 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.020559 |
| CPQ | carboxypeptidase Q | -0.0203392 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.020264 |
