| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.119388 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0965596 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0891138 |
| MEF2A | myocyte enhancer factor 2A | 0.081929 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0816698 |
| MSN | moesin | 0.0776313 |
| POTEF | POTE ankyrin domain family, member F | 0.0730037 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0684039 |
| CLIC4 | chloride intracellular channel 4 | 0.0674196 |
| B2M | beta-2-microglobulin | 0.0672025 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0664738 |
| RASAL2 | RAS protein activator like 2 | 0.0643618 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0638066 |
| FLNB | filamin B, beta | 0.0625269 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0574841 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0561097 |
| ITGA6 | integrin, alpha 6 | 0.0561009 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0551364 |
| ENO1 | enolase 1, (alpha) | 0.054522 |
| RCOR1 | REST corepressor 1 | 0.0543757 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0541628 |
| INTS6 | integrator complex subunit 6 | 0.0513469 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0510934 |
| RAI14 | retinoic acid induced 14 | 0.0506086 |
| LAMC2 | laminin, gamma 2 | 0.0504161 |
| PLS3 | plastin 3 | 0.0499106 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.049561 |
| LUZP1 | leucine zipper protein 1 | 0.0462927 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0454442 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0452908 |
| PGK1 | phosphoglycerate kinase 1 | 0.0448801 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0445969 |
| TPM3 | tropomyosin 3 | 0.0440919 |
| MCL1 | myeloid cell leukemia 1 | 0.0438143 |
| DIAPH1 | diaphanous-related formin 1 | 0.04251 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0422355 |
| CLU | clusterin | 0.0415836 |
| JMJD1C | jumonji domain containing 1C | 0.0410973 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.040716 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.040289 |
| LDHA | lactate dehydrogenase A | 0.0402132 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0392261 |
| SLC35F3 | solute carrier family 35, member F3 | 0.038817 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0385536 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.038246 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0381828 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0377542 |
| VCL | vinculin | 0.0374067 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0372692 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0370708 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0365847 |
| SLK | STE20-like kinase | 0.0360803 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.035648 |
| CALB1 | calbindin 1, 28kDa | 0.034075 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0336802 |
| PCDH1 | protocadherin 1 | 0.0334986 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0334187 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0324734 |
| PLK2 | polo-like kinase 2 | 0.0319492 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0316039 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0312797 |
| VMP1 | vacuole membrane protein 1 | 0.0311675 |
| TGM2 | transglutaminase 2 | 0.031018 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0309688 |
| MTSS1 | metastasis suppressor 1 | 0.030724 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.030587 |
| FNIP1 | folliculin interacting protein 1 | 0.0302676 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.030237 |
| INSIG2 | insulin induced gene 2 | 0.030163 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0295271 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0295008 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0292846 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0290785 |
| SERTAD2 | SERTA domain containing 2 | 0.0290032 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0288979 |
| EFNA5 | ephrin-A5 | 0.0287308 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0281776 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0280272 |
| RAB10 | RAB10, member RAS oncogene family | 0.0278403 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0278168 |
| TJP1 | tight junction protein 1 | 0.0277317 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0276168 |
| COPA | coatomer protein complex, subunit alpha | 0.0274791 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0271915 |
| PGM3 | phosphoglucomutase 3 | 0.0267664 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0267613 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0266748 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0266373 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0264735 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0262275 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0261461 |
| ARRDC3 | arrestin domain containing 3 | 0.0260164 |
| LIMA1 | LIM domain and actin binding 1 | 0.0260141 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0259959 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0256111 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0255815 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0253989 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0250713 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0250479 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0249457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.117374 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.107327 |
| TMSB10 | thymosin beta 10 | -0.0795645 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0732359 |
| AOPEP | aminopeptidase O (putative) | -0.0709298 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0700321 |
| PLEC | plectin | -0.0654711 |
| RPLP1 | ribosomal protein, large, P1 | -0.063217 |
| RPS21 | ribosomal protein S21 | -0.061124 |
| GNAS | GNAS complex locus | -0.0574254 |
| H1-0 | H1.0 linker histone | -0.0543096 |
| LMNA | lamin A/C | -0.0535537 |
| OSMR | oncostatin M receptor | -0.0535435 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0521158 |
| FLNA | filamin A, alpha | -0.0500726 |
| RPL11 | ribosomal protein L11 | -0.0483557 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0472198 |
| FOXP1 | forkhead box P1 | -0.0468046 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0467953 |
| RPS24 | ribosomal protein S24 | -0.0460818 |
| RIN2 | Ras and Rab interactor 2 | -0.0451619 |
| CAVIN1 | caveolae associated protein 1 | -0.0449059 |
| IGF2 | insulin-like growth factor 2 | -0.0422613 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0413951 |
| MT2A | metallothionein 2A | -0.0409198 |
| RPL23 | ribosomal protein L23 | -0.0406885 |
| RPL34 | ribosomal protein L34 | -0.0398026 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0389522 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0385783 |
| ARF1 | ADP-ribosylation factor 1 | -0.0379326 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0378995 |
| RPLP2 | ribosomal protein, large, P2 | -0.0377669 |
| SULF1 | sulfatase 1 | -0.0368801 |
| RRBP1 | ribosome binding protein 1 | -0.0352618 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0349947 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0347694 |
| S100A2 | S100 calcium binding protein A2 | -0.0337291 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0329489 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0326606 |
| RPL12 | ribosomal protein L12 | -0.0324048 |
| FN1 | fibronectin 1 | -0.0323725 |
| LAMA5 | laminin, alpha 5 | -0.0313083 |
| NRCAM | neuronal cell adhesion molecule | -0.0310974 |
| RACK1 | receptor for activated C kinase 1 | -0.0310061 |
| RPL30 | ribosomal protein L30 | -0.0308752 |
| RBM39 | RNA binding motif protein 39 | -0.030825 |
| IER3 | immediate early response 3 | -0.0307909 |
| PLAT | plasminogen activator, tissue | -0.0302463 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0298435 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0293889 |
| RPL27A | ribosomal protein L27a | -0.0293137 |
| RIGI | RNA sensor RIG-I | -0.0291938 |
| NDRG1 | N-myc downstream regulated 1 | -0.028503 |
| ASPH | aspartate beta-hydroxylase | -0.02847 |
| OGA | O-GlcNAcase | -0.0284622 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0283682 |
| ANXA2 | annexin A2 | -0.0278376 |
| MECOM | MDS1 and EVI1 complex locus | -0.0276992 |
| RPLP0 | ribosomal protein, large, P0 | -0.0275362 |
| NRG1 | neuregulin 1 | -0.0273547 |
| RPL37A | ribosomal protein L37a | -0.0273064 |
| RPL37 | ribosomal protein L37 | -0.0272623 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0271442 |
| RPL26 | ribosomal protein L26 | -0.0269017 |
| SMYD3 | SET and MYND domain containing 3 | -0.0266804 |
| S100A4 | S100 calcium binding protein A4 | -0.0266629 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0263496 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0263183 |
| RPL36 | ribosomal protein L36 | -0.0262886 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0262265 |
| RPS3 | ribosomal protein S3 | -0.0261977 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0261721 |
| RPS8 | ribosomal protein S8 | -0.0260451 |
| S100A10 | S100 calcium binding protein A10 | -0.0259757 |
| OGFR | opioid growth factor receptor | -0.0259618 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0259245 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.02574 |
| ZFR | zinc finger RNA binding protein | -0.0252155 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0251477 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0251001 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0250814 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0250719 |
| RBBP6 | retinoblastoma binding protein 6 | -0.024976 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0246259 |
| AHNAK | AHNAK nucleoprotein | -0.0245642 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0245573 |
| RPL8 | ribosomal protein L8 | -0.02449 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0242425 |
| RPL35A | ribosomal protein L35a | -0.0241514 |
| SYNJ2 | synaptojanin 2 | -0.0241449 |
| RPS4X | ribosomal protein S4, X-linked | -0.0240801 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0240682 |
| S100A6 | S100 calcium binding protein A6 | -0.0239853 |
| PRELID2 | PRELI domain containing 2 | -0.0238682 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0237651 |
| BSG | basigin (Ok blood group) | -0.023666 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0234642 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0234301 |
| GM2A | GM2 ganglioside activator | -0.0233342 |
| HMGB1 | high mobility group box 1 | -0.0232914 |
