| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Valdecoxib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.179288 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.146595 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0666825 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0474641 |
| TXNRD1 | thioredoxin reductase 1 | 0.0406989 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.040675 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0402957 |
| TMEM41B | transmembrane protein 41B | 0.0390802 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0380132 |
| MKI67 | marker of proliferation Ki-67 | 0.0363511 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0341345 |
| TXNIP | thioredoxin interacting protein | 0.0327638 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0322751 |
| FNIP1 | folliculin interacting protein 1 | 0.0321434 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0319042 |
| NUP58 | nucleoporin 58 | 0.0305092 |
| UBC | ubiquitin C | 0.0296975 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0282518 |
| RTN4 | reticulon 4 | 0.0280517 |
| ARRDC3 | arrestin domain containing 3 | 0.0261102 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0248731 |
| POTEF | POTE ankyrin domain family, member F | 0.0246301 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0244308 |
| TPM3 | tropomyosin 3 | 0.0242128 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0240266 |
| EREG | epiregulin | 0.0235691 |
| HJURP | Holliday junction recognition protein | 0.0234342 |
| USP34 | ubiquitin specific peptidase 34 | 0.023189 |
| VIM | vimentin | 0.0227516 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0219145 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0216019 |
| ATP13A3 | ATPase type 13A3 | 0.0215741 |
| TMSB4X | thymosin beta 4, X-linked | 0.0211282 |
| UPP1 | uridine phosphorylase 1 | 0.020917 |
| OGA | O-GlcNAcase | 0.02074 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0205321 |
| CENPF | centromere protein F, 350/400kDa | 0.0204748 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0204606 |
| INSIG1 | insulin induced gene 1 | 0.0202714 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0201472 |
| PLIN2 | perilipin 2 | 0.020083 |
| IPO7 | importin 7 | 0.0199433 |
| RAI1 | retinoic acid induced 1 | 0.0196368 |
| RRM2 | ribonucleotide reductase M2 | 0.0185756 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0184954 |
| PLK2 | polo-like kinase 2 | 0.0184588 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0183914 |
| CAPRIN2 | caprin family member 2 | 0.018135 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0179743 |
| SPAG9 | sperm associated antigen 9 | 0.0179011 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0178788 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0176142 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0173878 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0173186 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0172919 |
| PANK3 | pantothenate kinase 3 | 0.0170754 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.016967 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0169227 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0164193 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0160787 |
| RPL3 | ribosomal protein L3 | 0.0160051 |
| MSN | moesin | 0.0159061 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0158432 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.015792 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0157334 |
| ECT2 | epithelial cell transforming 2 | 0.0156811 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0155627 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | 0.0155044 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0154783 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0153045 |
| ATL2 | atlastin GTPase 2 | 0.0152556 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0151933 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0150817 |
| RASAL2 | RAS protein activator like 2 | 0.0150754 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0150055 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0148122 |
| VMP1 | vacuole membrane protein 1 | 0.0147102 |
| NAV2 | neuron navigator 2 | 0.0145785 |
| KIF1B | kinesin family member 1B | 0.0145627 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0144829 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0144009 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0143042 |
| BARX2 | BARX homeobox 2 | 0.0142175 |
| ANK2 | ankyrin 2, neuronal | 0.0142079 |
| JMJD1C | jumonji domain containing 1C | 0.0141782 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0140938 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0140363 |
| ABI1 | abl-interactor 1 | 0.0139641 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0139599 |
| YEATS2 | YEATS domain containing 2 | 0.0139559 |
| TPX2 | TPX2, microtubule-associated | 0.013934 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0139237 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0138505 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0138477 |
| SUCO | SUN domain containing ossification factor | 0.0136723 |
| RCOR1 | REST corepressor 1 | 0.013666 |
| USP24 | ubiquitin specific peptidase 24 | 0.0136406 |
| ANXA5 | annexin A5 | 0.0136249 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0135606 |
| GOLGA4 | golgin A4 | 0.0135358 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.126328 |
| TP63 | tumor protein p63 | -0.111193 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.108131 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.100573 |
| CD44 | CD44 molecule (Indian blood group) | -0.100141 |
| RIGI | RNA sensor RIG-I | -0.0922136 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0791832 |
| TMSB10 | thymosin beta 10 | -0.0687184 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0681036 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0663681 |
| CADM2 | cell adhesion molecule 2 | -0.0634787 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0624042 |
| DST | dystonin | -0.0613547 |
| EHBP1 | EH domain binding protein 1 | -0.0601649 |
| RNF213 | ring finger protein 213 | -0.0567784 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0564239 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0554689 |
| RAD51B | RAD51 paralog B | -0.0536166 |
| SP100 | SP100 nuclear antigen | -0.0522313 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0513418 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0503498 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0496743 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0494976 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0476185 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0455545 |
| EXOC4 | exocyst complex component 4 | -0.0454804 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0454527 |
| DNER | delta/notch-like EGF repeat containing | -0.0451632 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0435226 |
| PTK2 | protein tyrosine kinase 2 | -0.0433002 |
| RUNX1 | runt-related transcription factor 1 | -0.0397642 |
| SMYD3 | SET and MYND domain containing 3 | -0.0384197 |
| FTL | ferritin, light polypeptide | -0.0368606 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0363635 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0358078 |
| PMP22 | peripheral myelin protein 22 | -0.0353574 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0351133 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0350525 |
| RPL35A | ribosomal protein L35a | -0.0347063 |
| HDLBP | high density lipoprotein binding protein | -0.0342369 |
| AHNAK | AHNAK nucleoprotein | -0.0337061 |
| RAD50 | RAD50 homolog (S. cerevisiae) | -0.0329583 |
| GLG1 | golgi glycoprotein 1 | -0.0323902 |
| CMIP | c-Maf inducing protein | -0.0314316 |
| PLSCR1 | phospholipid scramblase 1 | -0.0311979 |
| TNS3 | tensin 3 | -0.0307113 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.030268 |
| ENO1 | enolase 1, (alpha) | -0.0300326 |
| PDE10A | phosphodiesterase 10A | -0.0297123 |
| RAB7A | RAB7A, member RAS oncogene family | -0.029575 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.029159 |
| APP | amyloid beta (A4) precursor protein | -0.0290945 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0290751 |
| HLA-B | major histocompatibility complex, class I, B | -0.0289295 |
| EGFR | epidermal growth factor receptor | -0.0288128 |
| RPS8 | ribosomal protein S8 | -0.0287392 |
| CDK6 | cyclin-dependent kinase 6 | -0.0284311 |
| EPHA4 | EPH receptor A4 | -0.028278 |
| PTMA | prothymosin, alpha | -0.028148 |
| GNAS | GNAS complex locus | -0.0279592 |
| ANKRD12 | ankyrin repeat domain 12 | -0.027882 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0278678 |
| MT2A | metallothionein 2A | -0.027657 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0272587 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0269952 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.026596 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0264919 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0262813 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0262412 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0258568 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0258106 |
| ACTG1 | actin gamma 1 | -0.0256715 |
| ANXA2 | annexin A2 | -0.0255839 |
| HMGA1 | high mobility group AT-hook 1 | -0.0254886 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0252716 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.025087 |
| DPH6 | diphthamine biosynthesis 6 | -0.024857 |
| PODXL | podocalyxin-like | -0.024851 |
| WDR27 | WD repeat domain 27 | -0.024192 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0238474 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0236921 |
| CALD1 | caldesmon 1 | -0.0235354 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0232317 |
| RPL5 | ribosomal protein L5 | -0.023157 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0229228 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0228304 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0227826 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0227689 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0227594 |
| PHF14 | PHD finger protein 14 | -0.0226867 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0225043 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0223733 |
| YBX3 | Y box binding protein 3 | -0.0221819 |
| PDGFC | platelet derived growth factor C | -0.0221614 |
| RPL36 | ribosomal protein L36 | -0.0220501 |
| CAVIN1 | caveolae associated protein 1 | -0.021815 |
| TPI1 | triosephosphate isomerase 1 | -0.0215173 |
| HDAC9 | histone deacetylase 9 | -0.0212952 |
| RPL13A | ribosomal protein L13a | -0.0212356 |
| RPS3 | ribosomal protein S3 | -0.0211902 |
