| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Valdecoxib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0757166 |
| TMEM165 | transmembrane protein 165 | 0.0432521 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.040874 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0404167 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.040153 |
| CES1 | carboxylesterase 1 | 0.0348419 |
| TXNRD1 | thioredoxin reductase 1 | 0.0339736 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.033361 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0309377 |
| SPAG9 | sperm associated antigen 9 | 0.0302815 |
| MKI67 | marker of proliferation Ki-67 | 0.0301161 |
| RNF145 | ring finger protein 145 | 0.0294719 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0284287 |
| TOP1 | topoisomerase (DNA) I | 0.0281899 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0278606 |
| ATP13A3 | ATPase type 13A3 | 0.0274601 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0265951 |
| ARGLU1 | arginine and glutamate rich 1 | 0.02602 |
| ANXA5 | annexin A5 | 0.0258583 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0254722 |
| NPTN | neuroplastin | 0.0248923 |
| TPD52 | tumor protein D52 | 0.0248872 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0248481 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0242496 |
| DENND4A | DENN/MADD domain containing 4A | 0.0240665 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0236123 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0230993 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0230828 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0230158 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0226139 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0221196 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0216248 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0215364 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0212968 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0206053 |
| YTHDC1 | YTH domain containing 1 | 0.0205961 |
| ARRDC3 | arrestin domain containing 3 | 0.020436 |
| NGLY1 | N-glycanase 1 | 0.0202188 |
| FAM13A | family with sequence similarity 13, member A | 0.0199763 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0194211 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0190658 |
| DSCAM | Down syndrome cell adhesion molecule | 0.018777 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0186698 |
| CCNL1 | cyclin L1 | 0.0186389 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0185209 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0184412 |
| SLMAP | sarcolemma associated protein | 0.0182446 |
| SRP54 | signal recognition particle 54kDa | 0.0181748 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0181445 |
| RASA2 | RAS p21 protein activator 2 | 0.017846 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0175226 |
| WASF2 | WAS protein family, member 2 | 0.0172006 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0170475 |
| INSIG2 | insulin induced gene 2 | 0.0170338 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0170234 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0169472 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0168733 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0168406 |
| USP47 | ubiquitin specific peptidase 47 | 0.0166865 |
| USP34 | ubiquitin specific peptidase 34 | 0.0165931 |
| RLIM | ring finger protein, LIM domain interacting | 0.0162937 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0161767 |
| UVRAG | UV radiation resistance associated | 0.0160461 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0157285 |
| MED13L | mediator complex subunit 13-like | 0.0156785 |
| HELZ | helicase with zinc finger | 0.0156716 |
| WDR26 | WD repeat domain 26 | 0.015662 |
| PPTC7 | PTC7 protein phosphatase homolog (S. cerevisiae) | 0.0156176 |
| CPE | carboxypeptidase E | 0.0154408 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0154264 |
| USP3 | ubiquitin specific peptidase 3 | 0.0153157 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0152344 |
| KMT5B | lysine methyltransferase 5B | 0.0152072 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0151614 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0150992 |
| TFG | TRK-fused gene | 0.0150871 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0150414 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0149898 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0149326 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0149257 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0149108 |
| DTNA | dystrobrevin, alpha | 0.0148929 |
| SUCO | SUN domain containing ossification factor | 0.0145984 |
| RUNX1 | runt-related transcription factor 1 | 0.0145114 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.014511 |
| NCKAP1 | NCK-associated protein 1 | 0.0144015 |
| OGA | O-GlcNAcase | 0.0140448 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0140416 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.013985 |
| RBM39 | RNA binding motif protein 39 | 0.0139691 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0138755 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0138631 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0135262 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0133308 |
| NUP58 | nucleoporin 58 | 0.0133056 |
| COPA | coatomer protein complex, subunit alpha | 0.0133026 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0132705 |
| WDR45B | WD repeat domain 45B | 0.0132634 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.013261 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0132579 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.319889 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.260695 |
| ASPH | aspartate beta-hydroxylase | -0.135159 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.120857 |
| TMSB10 | thymosin beta 10 | -0.118258 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.117169 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0886229 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0794901 |
| ACTG1 | actin gamma 1 | -0.0765998 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0711371 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0695474 |
| LDHA | lactate dehydrogenase A | -0.0652451 |
| ENO1 | enolase 1, (alpha) | -0.0639463 |
| S100A10 | S100 calcium binding protein A10 | -0.063433 |
| KRT18 | keratin 18, type I | -0.0613791 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0597198 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0580718 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0572121 |
| GRAMD1B | GRAM domain containing 1B | -0.0562586 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0535495 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0500658 |
| MYOF | myoferlin | -0.0499501 |
| PTMA | prothymosin, alpha | -0.0494155 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0479443 |
| AHNAK | AHNAK nucleoprotein | -0.0479134 |
| PKM | pyruvate kinase, muscle | -0.0475872 |
| SCEL | sciellin | -0.0466778 |
| KRT7 | keratin 7, type II | -0.0463527 |
| ANXA2 | annexin A2 | -0.0457228 |
| RPLP1 | ribosomal protein, large, P1 | -0.0448598 |
| CST3 | cystatin C | -0.0441744 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0436021 |
| EGR1 | early growth response 1 | -0.0430598 |
| CCND1 | cyclin D1 | -0.0427096 |
| LMO7 | LIM domain 7 | -0.0410099 |
| FTL | ferritin, light polypeptide | -0.0403048 |
| RPS8 | ribosomal protein S8 | -0.0396544 |
| RPS6 | ribosomal protein S6 | -0.0394591 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0393738 |
| RPL35A | ribosomal protein L35a | -0.0387491 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0385687 |
| INTS6 | integrator complex subunit 6 | -0.0379374 |
| RNF213 | ring finger protein 213 | -0.0362329 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0359264 |
| SEC61G | Sec61 gamma subunit | -0.0357168 |
| CUX1 | cut-like homeobox 1 | -0.035258 |
| RPS24 | ribosomal protein S24 | -0.0344676 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0342035 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0339304 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0329237 |
| RPL37A | ribosomal protein L37a | -0.0326665 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0325071 |
| RPS3 | ribosomal protein S3 | -0.032376 |
| VCL | vinculin | -0.0322834 |
| TPM4 | tropomyosin 4 | -0.0314446 |
| PRKCA | protein kinase C, alpha | -0.0313617 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0305323 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0304312 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0303526 |
| RPL34 | ribosomal protein L34 | -0.0295543 |
| DSPP | dentin sialophosphoprotein | -0.0294819 |
| RPL31 | ribosomal protein L31 | -0.0293775 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0292741 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0291958 |
| RPS12 | ribosomal protein S12 | -0.0289971 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0285209 |
| CAV2 | caveolin 2 | -0.0284015 |
| KRT19 | keratin 19, type I | -0.0284005 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0280135 |
| MYO1E | myosin IE | -0.0275991 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0271787 |
| RPS27A | ribosomal protein S27a | -0.0268959 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0267921 |
| KRT8 | keratin 8, type II | -0.0261638 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0259477 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0259439 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0258843 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0258082 |
| EFNA5 | ephrin-A5 | -0.0254236 |
| MORF4L2 | mortality factor 4 like 2 | -0.0253147 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0252499 |
| RPL19 | ribosomal protein L19 | -0.0252248 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0251221 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0245215 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0242114 |
| GNAS | GNAS complex locus | -0.0240874 |
| S100A11 | S100 calcium binding protein A11 | -0.0239316 |
| BPTF | bromodomain PHD finger transcription factor | -0.0238891 |
| RPS25 | ribosomal protein S25 | -0.0238074 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0236872 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0236768 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0233301 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0233113 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.02315 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0230417 |
| CMIP | c-Maf inducing protein | -0.0228899 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0227075 |
| EMP1 | epithelial membrane protein 1 | -0.0224459 |
| HDLBP | high density lipoprotein binding protein | -0.0224229 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0223111 |
