| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.148144 |
| KYNU | kynureninase | 0.133795 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0916746 |
| KRT17 | keratin 17, type I | 0.0887928 |
| FTL | ferritin, light polypeptide | 0.087383 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0842667 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0816631 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0730342 |
| ANLN | anillin, actin binding protein | 0.0712137 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0682596 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0673597 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0667254 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0647163 |
| FAT1 | FAT atypical cadherin 1 | 0.063658 |
| FAM193A | family with sequence similarity 193, member A | 0.0634092 |
| ASPH | aspartate beta-hydroxylase | 0.0616503 |
| RPL31 | ribosomal protein L31 | 0.0614406 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0613139 |
| PCBP2 | poly(rC) binding protein 2 | 0.0612896 |
| S100P | S100 calcium binding protein P | 0.0605258 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0565308 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0565024 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0519857 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0515913 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0487376 |
| YTHDC1 | YTH domain containing 1 | 0.0478294 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0478106 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0477446 |
| RPL7 | ribosomal protein L7 | 0.047726 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0470138 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.0470057 |
| ZNF207 | zinc finger protein 207 | 0.0463918 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0456564 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0431373 |
| FAF2 | Fas associated factor family member 2 | 0.0431231 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0429447 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0426635 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0399503 |
| SPAG9 | sperm associated antigen 9 | 0.0398867 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0396658 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0387942 |
| NUP58 | nucleoporin 58 | 0.0384544 |
| BTBD7 | BTB (POZ) domain containing 7 | 0.0383297 |
| RPLP1 | ribosomal protein, large, P1 | 0.0380963 |
| RPS3 | ribosomal protein S3 | 0.0378268 |
| NOP58 | NOP58 ribonucleoprotein | 0.0377435 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0371685 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.036963 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0364746 |
| LAMB3 | laminin, beta 3 | 0.0362146 |
| TXNRD1 | thioredoxin reductase 1 | 0.0358138 |
| RACK1 | receptor for activated C kinase 1 | 0.0353273 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0353066 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0344481 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0328915 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0328623 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.03273 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0321441 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0321072 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0319775 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0317647 |
| FAM13A | family with sequence similarity 13, member A | 0.0310803 |
| PKM | pyruvate kinase, muscle | 0.0305562 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0303943 |
| BRD2 | bromodomain containing 2 | 0.0302521 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0300685 |
| CANX | calnexin | 0.0295097 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.027811 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0272316 |
| GOLGB1 | golgin B1 | 0.0271156 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0255378 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0253345 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0246699 |
| PGK1 | phosphoglycerate kinase 1 | 0.0244863 |
| HELZ | helicase with zinc finger | 0.0239354 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0236975 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0236452 |
| RPL8 | ribosomal protein L8 | 0.0232404 |
| HMGA1 | high mobility group AT-hook 1 | 0.0228703 |
| SMYD3 | SET and MYND domain containing 3 | 0.0225736 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0223897 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0221508 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0219961 |
| PDE10A | phosphodiesterase 10A | 0.0218987 |
| PARD3 | par-3 family cell polarity regulator | 0.0218275 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0218175 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0214413 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0209254 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0208948 |
| TMSB10 | thymosin beta 10 | 0.018648 |
| PTMA | prothymosin, alpha | 0.0180178 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0178348 |
| RTN4 | reticulon 4 | 0.0177909 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0177662 |
| KIF5B | kinesin family member 5B | 0.0177515 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0176016 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0174148 |
| GOLGA4 | golgin A4 | 0.0167753 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0166379 |
| RND3 | Rho family GTPase 3 | 0.0145484 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.183597 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.123028 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.113403 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.111609 |
| MUC16 | mucin 16, cell surface associated | -0.110284 |
| GRB10 | growth factor receptor-bound protein 10 | -0.105959 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105957 |
| NDRG1 | N-myc downstream regulated 1 | -0.104685 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.102535 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0907998 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0901677 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0786085 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0748371 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0745855 |
| MYO1E | myosin IE | -0.0743863 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0731201 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0691512 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0679639 |
| HLA-B | major histocompatibility complex, class I, B | -0.0658056 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.063902 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0633377 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0628971 |
| EMP1 | epithelial membrane protein 1 | -0.06171 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0607783 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0599762 |
| ATP13A3 | ATPase type 13A3 | -0.0597103 |
| B2M | beta-2-microglobulin | -0.0593697 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0592974 |
| NF1 | neurofibromin 1 | -0.0577547 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0567783 |
| SRPK2 | SRSF protein kinase 2 | -0.0539306 |
| LMO7 | LIM domain 7 | -0.053135 |
| SVIL | supervillin | -0.0522342 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0516098 |
| JMJD1C | jumonji domain containing 1C | -0.0514207 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0509636 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.050827 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0507947 |
| AFTPH | aftiphilin | -0.0499357 |
| RBM39 | RNA binding motif protein 39 | -0.0498585 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.048212 |
| EGFR | epidermal growth factor receptor | -0.0477539 |
| CALR | calreticulin | -0.0476608 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0474637 |
| SQSTM1 | sequestosome 1 | -0.0473133 |
| AHNAK | AHNAK nucleoprotein | -0.0472785 |
| RAD51B | RAD51 paralog B | -0.0449159 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0434279 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0415664 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0407982 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0396806 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0394609 |
| VIM | vimentin | -0.0387399 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0381641 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0380983 |
| ANXA2 | annexin A2 | -0.0380235 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0368556 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0355697 |
| CCNY | cyclin Y | -0.0348696 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0330548 |
| GPC6 | glypican 6 | -0.0308782 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0308522 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0303669 |
| RPS6 | ribosomal protein S6 | -0.0302908 |
| ZNF638 | zinc finger protein 638 | -0.0295946 |
| PCM1 | pericentriolar material 1 | -0.0268568 |
| RPS2 | ribosomal protein S2 | -0.0257368 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0256666 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0255514 |
| PTK2 | protein tyrosine kinase 2 | -0.0252288 |
| GPHN | gephyrin | -0.0250804 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0245283 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0244133 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0243379 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0239527 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0237432 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0235812 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0234202 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0233445 |
| AK1 | adenylate kinase 1 | -0.0231515 |
| ZNF292 | zinc finger protein 292 | -0.022389 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0220918 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0218726 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0203574 |
| GNAS | GNAS complex locus | -0.0203536 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0200318 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.019909 |
| RUNX1 | runt-related transcription factor 1 | -0.0189849 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0188899 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0176419 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0159843 |
| INSIG1 | insulin induced gene 1 | -0.0155428 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0152894 |
| ENO1 | enolase 1, (alpha) | -0.0150141 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0144487 |
| MEF2A | myocyte enhancer factor 2A | -0.0142717 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0140131 |
| APP | amyloid beta (A4) precursor protein | -0.013822 |
| FN1 | fibronectin 1 | -0.0137092 |
| DST | dystonin | -0.0121772 |
