| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.265964 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.163085 |
| TXNRD1 | thioredoxin reductase 1 | 0.133759 |
| GRAMD1B | GRAM domain containing 1B | 0.116277 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0836218 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0823509 |
| STC1 | stanniocalcin 1 | 0.078347 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.074839 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0715603 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0564978 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0522201 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0515754 |
| YBX3 | Y box binding protein 3 | 0.0512133 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0506543 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0498268 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0486506 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0482379 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0482058 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.047398 |
| MMP12 | matrix metallopeptidase 12 | 0.04637 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0455573 |
| ANO6 | anoctamin 6 | 0.0451489 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0448738 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0448444 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0446328 |
| CDK17 | cyclin-dependent kinase 17 | 0.0430542 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0427478 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0423674 |
| MED13L | mediator complex subunit 13-like | 0.0422249 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0418276 |
| PHF20 | PHD finger protein 20 | 0.0383494 |
| PGK1 | phosphoglycerate kinase 1 | 0.037677 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.037599 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.037324 |
| ATP11A | ATPase, class VI, type 11A | 0.0370869 |
| RNF145 | ring finger protein 145 | 0.036547 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0365411 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0362469 |
| CCDC91 | coiled-coil domain containing 91 | 0.0359917 |
| VCL | vinculin | 0.0359495 |
| SET | SET nuclear proto-oncogene | 0.0357674 |
| EXOC4 | exocyst complex component 4 | 0.0357046 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0356995 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0354765 |
| POTEF | POTE ankyrin domain family, member F | 0.0354682 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0347463 |
| TPM3 | tropomyosin 3 | 0.0347036 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0346777 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0344291 |
| RASAL2 | RAS protein activator like 2 | 0.034247 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0339247 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0338953 |
| DST | dystonin | 0.0330622 |
| RTN4 | reticulon 4 | 0.0330199 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0327027 |
| SERINC3 | serine incorporator 3 | 0.0325534 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0323365 |
| MYOF | myoferlin | 0.0321338 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0319654 |
| PLCB4 | phospholipase C, beta 4 | 0.0315449 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0314071 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0313948 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0312339 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0311144 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0310636 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0297573 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0296817 |
| USP34 | ubiquitin specific peptidase 34 | 0.0292449 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0290602 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0287016 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0286613 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0282638 |
| NRDC | nardilysin convertase | 0.0281893 |
| SMAD3 | SMAD family member 3 | 0.0279577 |
| RAB10 | RAB10, member RAS oncogene family | 0.0279108 |
| MCL1 | myeloid cell leukemia 1 | 0.0274324 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0274283 |
| FMNL2 | formin-like 2 | 0.0273753 |
| CLTC | clathrin, heavy chain (Hc) | 0.0272105 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0269696 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0269462 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0268892 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0267519 |
| MYPN | myopalladin | 0.0266655 |
| ZNF638 | zinc finger protein 638 | 0.0265382 |
| NBEAL1 | neurobeachin-like 1 | 0.0265097 |
| TMEM41B | transmembrane protein 41B | 0.0262678 |
| CCNL1 | cyclin L1 | 0.0258828 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0258561 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0254607 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0253422 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0253132 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0252417 |
| BBX | bobby sox homolog (Drosophila) | 0.024892 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0246967 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0245306 |
| OSMR | oncostatin M receptor | 0.0245003 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0244449 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0241418 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0238394 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0989192 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0948524 |
| PTMA | prothymosin, alpha | -0.0729017 |
| TMSB10 | thymosin beta 10 | -0.0578917 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0559442 |
| RPL35A | ribosomal protein L35a | -0.0545664 |
| RPS8 | ribosomal protein S8 | -0.0539262 |
| RPL12 | ribosomal protein L12 | -0.0502562 |
| RPL23 | ribosomal protein L23 | -0.0464899 |
| GNAS | GNAS complex locus | -0.0448942 |
| RAD51B | RAD51 paralog B | -0.0406118 |
| RPL37A | ribosomal protein L37a | -0.0398695 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0358002 |
| RPS19 | ribosomal protein S19 | -0.0350082 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0346264 |
| RPL34 | ribosomal protein L34 | -0.034552 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343984 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343391 |
| RPL37 | ribosomal protein L37 | -0.030949 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0297072 |
| RPS3 | ribosomal protein S3 | -0.0292494 |
| YBX1 | Y box binding protein 1 | -0.0291288 |
| RPL9 | ribosomal protein L9 | -0.028491 |
| RPL36 | ribosomal protein L36 | -0.0281251 |
| RPS10 | ribosomal protein S10 | -0.0279378 |
| RPL26 | ribosomal protein L26 | -0.0278765 |
| RPS20 | ribosomal protein S20 | -0.0278125 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0276359 |
| PFN1 | profilin 1 | -0.0272697 |
| RPS12 | ribosomal protein S12 | -0.0255288 |
| H1-0 | H1.0 linker histone | -0.0255268 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0254662 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0254579 |
| TMEM131 | transmembrane protein 131 | -0.0252621 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0238494 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0232579 |
| RPLP0 | ribosomal protein, large, P0 | -0.0230306 |
| FTL | ferritin, light polypeptide | -0.0229735 |
| RPL5 | ribosomal protein L5 | -0.0229344 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0225142 |
| MORF4L2 | mortality factor 4 like 2 | -0.0220467 |
| RPL18 | ribosomal protein L18 | -0.0214011 |
| SCFD1 | sec1 family domain containing 1 | -0.0213517 |
| PHIP | pleckstrin homology domain interacting protein | -0.0210918 |
| RPS4X | ribosomal protein S4, X-linked | -0.0210852 |
| RPS27 | ribosomal protein S27 | -0.0209235 |
| RPL19 | ribosomal protein L19 | -0.0207014 |
| RPS29 | ribosomal protein S29 | -0.0203609 |
| ACTG1 | actin gamma 1 | -0.0203032 |
| HMGB2 | high mobility group box 2 | -0.0202886 |
| SEPTIN7 | septin 7 | -0.0202235 |
| RPS21 | ribosomal protein S21 | -0.0202201 |
| ATF6 | activating transcription factor 6 | -0.0201754 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0201622 |
| CALR | calreticulin | -0.0201278 |
| HMGA1 | high mobility group AT-hook 1 | -0.0198446 |
| ANXA2 | annexin A2 | -0.0197462 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.019697 |
| RPL32 | ribosomal protein L32 | -0.0196892 |
| S100A10 | S100 calcium binding protein A10 | -0.0196412 |
| RPL11 | ribosomal protein L11 | -0.0196241 |
| RPL28 | ribosomal protein L28 | -0.0193935 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0193284 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0193256 |
| ZFR | zinc finger RNA binding protein | -0.0192643 |
| RPL30 | ribosomal protein L30 | -0.0191946 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0191929 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0191104 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0188695 |
| GPHN | gephyrin | -0.0187586 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0185164 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0183585 |
| PCBP2 | poly(rC) binding protein 2 | -0.0179108 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0176348 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0174439 |
| TUBA1B | tubulin, alpha 1b | -0.0174183 |
| RBM39 | RNA binding motif protein 39 | -0.0173911 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0173296 |
| SCFD2 | sec1 family domain containing 2 | -0.0170953 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0170647 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0168824 |
| RPL38 | ribosomal protein L38 | -0.0166864 |
| RACK1 | receptor for activated C kinase 1 | -0.0165559 |
| KIF4A | kinesin family member 4A | -0.0165299 |
| CDK12 | cyclin-dependent kinase 12 | -0.016476 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.016466 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0163779 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0162034 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -0.0161963 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0161814 |
| MTF2 | metal response element binding transcription factor 2 | -0.0160782 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0160011 |
| SLC39A9 | solute carrier family 39, member 9 | -0.0159481 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0158118 |
| ANLN | anillin, actin binding protein | -0.0156819 |
| LDHB | lactate dehydrogenase B | -0.0156572 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0156514 |
| TPX2 | TPX2, microtubule-associated | -0.015592 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0151692 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.015146 |
