| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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92 genes differentially expressed following the Valdecoxib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.166915 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.155408 |
| VIM | vimentin | 0.140709 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.137614 |
| TMSB10 | thymosin beta 10 | 0.128742 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.127856 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.127191 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.123873 |
| RPS6 | ribosomal protein S6 | 0.123838 |
| PKM | pyruvate kinase, muscle | 0.12283 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.118915 |
| RTN4 | reticulon 4 | 0.1175 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.100958 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0925714 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0911781 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0863337 |
| ANXA2 | annexin A2 | 0.0846354 |
| POTEF | POTE ankyrin domain family, member F | 0.0695947 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0690866 |
| DST | dystonin | 0.0659029 |
| STC1 | stanniocalcin 1 | 0.0625397 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.061047 |
| SEPTIN2 | septin 2 | 0.0607752 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0554756 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0554122 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0544665 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0534491 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0425708 |
| PCBP2 | poly(rC) binding protein 2 | 0.0422668 |
| CD44 | CD44 molecule (Indian blood group) | 0.041894 |
| ENO1 | enolase 1, (alpha) | 0.0403974 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0393325 |
| RIGI | RNA sensor RIG-I | 0.0368838 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0366403 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.03601 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.030942 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0290503 |
| PRELID2 | PRELI domain containing 2 | 0.0280791 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0244059 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0220314 |
| APP | amyloid beta (A4) precursor protein | 0.0184083 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0110103 |
| ASPH | aspartate beta-hydroxylase | 0.00800382 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.00660725 |
| OGA | O-GlcNAcase | 0.00370776 |
| BBX | bobby sox homolog (Drosophila) | 0.00159631 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.418827 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.366138 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.188971 |
| PARD3 | par-3 family cell polarity regulator | -0.160326 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.15505 |
| GPC6 | glypican 6 | -0.129503 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.128618 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.115903 |
| PDE10A | phosphodiesterase 10A | -0.115441 |
| PDLIM5 | PDZ and LIM domain 5 | -0.110022 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.109857 |
| EGFR | epidermal growth factor receptor | -0.108542 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0936956 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0868322 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0866535 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0801242 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0756877 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0674718 |
| MYO1E | myosin IE | -0.0649257 |
| RORA | RAR-related orphan receptor A | -0.0616065 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0512838 |
| FNDC3A | fibronectin type III domain containing 3A | -0.048433 |
| AOPEP | aminopeptidase O (putative) | -0.0397745 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0397405 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0380597 |
| ATXN1 | ataxin 1 | -0.0378266 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0372769 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0368123 |
| CDH13 | cadherin 13 | -0.0362965 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0339831 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.033214 |
| VCL | vinculin | -0.0268952 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0263422 |
| PGK1 | phosphoglycerate kinase 1 | -0.0258377 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0248857 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0230856 |
| NDRG1 | N-myc downstream regulated 1 | -0.0229665 |
| EFNA5 | ephrin-A5 | -0.0182221 |
| SBF2 | SET binding factor 2 | -0.013216 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0125435 |
| TCF12 | transcription factor 12 | -0.00929631 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00781147 |
| SMYD3 | SET and MYND domain containing 3 | -0.00685821 |
| LDHA | lactate dehydrogenase A | -0.00655891 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00527485 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.00453037 |
