| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Valdecoxib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0988539 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0923014 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0905126 |
| TMSB4X | thymosin beta 4, X-linked | 0.0845038 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0825173 |
| POTEF | POTE ankyrin domain family, member F | 0.0787098 |
| TMEM65 | transmembrane protein 65 | 0.0771038 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0741475 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0720872 |
| PGK1 | phosphoglycerate kinase 1 | 0.0705584 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0693314 |
| VCL | vinculin | 0.0668075 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0650504 |
| ENO1 | enolase 1, (alpha) | 0.0644336 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0621243 |
| TXNRD1 | thioredoxin reductase 1 | 0.0613481 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0604885 |
| GOLGA4 | golgin A4 | 0.0581305 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0534807 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0527443 |
| SET | SET nuclear proto-oncogene | 0.0515111 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0497463 |
| FNIP1 | folliculin interacting protein 1 | 0.0477485 |
| EFNA5 | ephrin-A5 | 0.0475143 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0470513 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0464638 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0464584 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0446553 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0443249 |
| NBAS | neuroblastoma amplified sequence | 0.0430126 |
| PRELID2 | PRELI domain containing 2 | 0.0429963 |
| PDGFC | platelet derived growth factor C | 0.042959 |
| SFTPA2 | surfactant protein A2 | 0.041107 |
| SQSTM1 | sequestosome 1 | 0.0410881 |
| PLK2 | polo-like kinase 2 | 0.0405649 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0401002 |
| COPA | coatomer protein complex, subunit alpha | 0.0392326 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0391791 |
| USP24 | ubiquitin specific peptidase 24 | 0.0378852 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0378561 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0376604 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0373651 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0372708 |
| CANX | calnexin | 0.0371966 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0370728 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.036894 |
| NBEA | neurobeachin | 0.0368786 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0368169 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0367756 |
| EZR | ezrin | 0.036219 |
| ANK2 | ankyrin 2, neuronal | 0.0357598 |
| TXNIP | thioredoxin interacting protein | 0.0355403 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0343452 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0342296 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0339528 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0334119 |
| LDHA | lactate dehydrogenase A | 0.0333706 |
| COG5 | component of oligomeric golgi complex 5 | 0.0330867 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0330574 |
| NCKAP1 | NCK-associated protein 1 | 0.0330112 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.032741 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 0.0323376 |
| FOXJ3 | forkhead box J3 | 0.0322723 |
| MED13L | mediator complex subunit 13-like | 0.0322526 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0321141 |
| TJP1 | tight junction protein 1 | 0.032046 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0318266 |
| HSPA8 | heat shock 70kDa protein 8 | 0.031733 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0316223 |
| SEPTIN11 | septin 11 | 0.0313483 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0313005 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0312935 |
| NUP58 | nucleoporin 58 | 0.0306193 |
| CD47 | CD47 molecule | 0.030141 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0298807 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0298709 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0297185 |
| FAT1 | FAT atypical cadherin 1 | 0.0296462 |
| PYGB | phosphorylase, glycogen; brain | 0.029126 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0290314 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.028922 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.028692 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0286781 |
| USP3 | ubiquitin specific peptidase 3 | 0.028544 |
| LOXL3 | lysyl oxidase-like 3 | 0.0284865 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0284598 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.028299 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0282409 |
| YEATS2 | YEATS domain containing 2 | 0.0282218 |
| CLIC4 | chloride intracellular channel 4 | 0.0281692 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0280245 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0278853 |
| RTN4 | reticulon 4 | 0.0278032 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0277601 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0276344 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0275292 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0274942 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.027464 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0272499 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0270947 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.0924583 |
| RPLP1 | ribosomal protein, large, P1 | -0.0684394 |
| RPS6 | ribosomal protein S6 | -0.0657711 |
| RPL35A | ribosomal protein L35a | -0.0600239 |
| RPS8 | ribosomal protein S8 | -0.058657 |
| RPL34 | ribosomal protein L34 | -0.0491748 |
| RPL12 | ribosomal protein L12 | -0.0472987 |
| RPL26 | ribosomal protein L26 | -0.0462541 |
| RPS13 | ribosomal protein S13 | -0.0455387 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0444357 |
| RPL11 | ribosomal protein L11 | -0.0435628 |
| BMP10 | bone morphogenetic protein 10 | -0.04186 |
| LOC112694756 | uncharaterized LOC112694756 | -0.041762 |
| FUS | FUS RNA binding protein | -0.0408239 |
| GLI2 | GLI family zinc finger 2 | -0.0407449 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0379239 |
| RPS19 | ribosomal protein S19 | -0.0362666 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0361475 |
| RRBP1 | ribosome binding protein 1 | -0.0352776 |
| RPL19 | ribosomal protein L19 | -0.0345924 |
| CTBP2 | C-terminal binding protein 2 | -0.0337803 |
| RHEB | Ras homolog enriched in brain | -0.0335063 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0333192 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0333073 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0327587 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0309576 |
| DIAPH3 | diaphanous-related formin 3 | -0.030539 |
| RPL36 | ribosomal protein L36 | -0.0302805 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0301995 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0295403 |
| RPL37A | ribosomal protein L37a | -0.0288261 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0285113 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0282401 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0280618 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0278062 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0268916 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0268123 |
| S100A6 | S100 calcium binding protein A6 | -0.0267885 |
| AHNAK | AHNAK nucleoprotein | -0.0267155 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0264637 |
| CCNY | cyclin Y | -0.0263591 |
| FOXP1 | forkhead box P1 | -0.0258442 |
| RPLP2 | ribosomal protein, large, P2 | -0.0256242 |
| CLINT1 | clathrin interactor 1 | -0.0255253 |
| RPL23 | ribosomal protein L23 | -0.0253722 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0252344 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0250452 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0243455 |
| HMGB1 | high mobility group box 1 | -0.0241953 |
| RPL5 | ribosomal protein L5 | -0.0241605 |
| INO80 | INO80 complex subunit | -0.0241123 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0239565 |
| EVI5 | ecotropic viral integration site 5 | -0.0233949 |
| MYO5C | myosin VC | -0.0231636 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0230798 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0230525 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0228037 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0226159 |
| RPS16 | ribosomal protein S16 | -0.0225987 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0225452 |
| RPL9 | ribosomal protein L9 | -0.022403 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.022397 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0221384 |
| MACROD2 | MACRO domain containing 2 | -0.0218418 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.021657 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0215867 |
| PHF21A | PHD finger protein 21A | -0.0215213 |
| PFN1 | profilin 1 | -0.0213906 |
| RPS25 | ribosomal protein S25 | -0.0210422 |
| RPL13A | ribosomal protein L13a | -0.020918 |
| RPS23 | ribosomal protein S23 | -0.0207282 |
| RPL28 | ribosomal protein L28 | -0.0207221 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.020718 |
| GSE1 | Gse1 coiled-coil protein | -0.020532 |
| ACTG1 | actin gamma 1 | -0.0205019 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0204849 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0204323 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.020419 |
| RPL30 | ribosomal protein L30 | -0.020254 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0201035 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0199602 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0197686 |
| RPL18 | ribosomal protein L18 | -0.0197001 |
| ZNF207 | zinc finger protein 207 | -0.0196659 |
| RPL38 | ribosomal protein L38 | -0.0196536 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.019484 |
| RPL35 | ribosomal protein L35 | -0.0194341 |
| RPL7A | ribosomal protein L7a | -0.0192747 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0192743 |
| RPL4 | ribosomal protein L4 | -0.0192328 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0192078 |
| RPS10 | ribosomal protein S10 | -0.0189603 |
| UBAP2L | ubiquitin associated protein 2-like | -0.0189525 |
| RPS29 | ribosomal protein S29 | -0.0186392 |
| SAE1 | SUMO1 activating enzyme subunit 1 | -0.0185335 |
| RPS21 | ribosomal protein S21 | -0.0184582 |
| WWOX | WW domain containing oxidoreductase | -0.0183999 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0183676 |
| RLF | rearranged L-myc fusion | -0.0183636 |
| RPS12 | ribosomal protein S12 | -0.0183524 |
