| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.150648 |
| VEGFA | vascular endothelial growth factor A | 0.0825524 |
| HDAC9 | histone deacetylase 9 | 0.0823214 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.081599 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0801384 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.076484 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0705871 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0701006 |
| RND3 | Rho family GTPase 3 | 0.0660508 |
| PLIN2 | perilipin 2 | 0.0601677 |
| NAV2 | neuron navigator 2 | 0.0587078 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0575611 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0545826 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0540377 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0531048 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0525218 |
| PDE10A | phosphodiesterase 10A | 0.0501399 |
| VCAN | versican | 0.0497915 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0480442 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0475386 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0465392 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0455914 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.045194 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0439145 |
| MMP12 | matrix metallopeptidase 12 | 0.0409845 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0408213 |
| MYOF | myoferlin | 0.0407671 |
| GOLGA4 | golgin A4 | 0.0399754 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0391725 |
| FNIP1 | folliculin interacting protein 1 | 0.0386385 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0384732 |
| FMNL2 | formin-like 2 | 0.0373153 |
| SFTPA2 | surfactant protein A2 | 0.0372391 |
| JMJD1C | jumonji domain containing 1C | 0.0368345 |
| EGR1 | early growth response 1 | 0.0361694 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0356119 |
| PCBP3 | poly(rC) binding protein 3 | 0.0343058 |
| ARRDC3 | arrestin domain containing 3 | 0.034237 |
| CD44 | CD44 molecule (Indian blood group) | 0.0331148 |
| KLHL24 | kelch-like family member 24 | 0.0330367 |
| CDK19 | cyclin-dependent kinase 19 | 0.0305202 |
| ASPH | aspartate beta-hydroxylase | 0.0304322 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0299093 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0289273 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0289125 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0283074 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.027877 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0273188 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0269189 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0261687 |
| PGM3 | phosphoglucomutase 3 | 0.0258371 |
| NDRG1 | N-myc downstream regulated 1 | 0.0257865 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0253831 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0253628 |
| STC2 | stanniocalcin 2 | 0.0252058 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0250742 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.024786 |
| FBXO32 | F-box protein 32 | 0.0238604 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0237374 |
| RUNX1 | runt-related transcription factor 1 | 0.0237298 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0237171 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0234514 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0232229 |
| CD109 | CD109 molecule | 0.022665 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.022588 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0223378 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0223063 |
| RAD51B | RAD51 paralog B | 0.0222352 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0222219 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0221938 |
| LDHA | lactate dehydrogenase A | 0.0221589 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0221099 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0205904 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0205343 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0205243 |
| DTNA | dystrobrevin, alpha | 0.0204634 |
| FLOT1 | flotillin 1 | 0.0203888 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0203592 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0203507 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0201922 |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.0201792 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0195822 |
| MSN | moesin | 0.0195004 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0194321 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.019429 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0193619 |
| SEPTIN9 | septin 9 | 0.0193067 |
| NOTCH2 | notch 2 | 0.0192918 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0192552 |
| PRKCE | protein kinase C, epsilon | 0.0192306 |
| CDH13 | cadherin 13 | 0.0188609 |
| CORO1C | coronin, actin binding protein, 1C | 0.0183318 |
| EPHA6 | EPH receptor A6 | 0.0182966 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0181565 |
| KYNU | kynureninase | 0.0180721 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0180125 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0179062 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0178328 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0176658 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0176105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.115213 |
| BICC1 | BicC family RNA binding protein 1 | -0.105309 |
| FRMD4A | FERM domain containing 4A | -0.0974581 |
| GLIS3 | GLIS family zinc finger 3 | -0.0937194 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0926073 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0862886 |
| TMSB10 | thymosin beta 10 | -0.0835359 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0804951 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.075354 |
| AHNAK | AHNAK nucleoprotein | -0.0691067 |
| PGK1 | phosphoglycerate kinase 1 | -0.0631225 |
| THBS1 | thrombospondin 1 | -0.0607891 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0581179 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0578516 |
| PTMA | prothymosin, alpha | -0.057509 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0572733 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0557931 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0555064 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0551076 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0539909 |
| RPS27A | ribosomal protein S27a | -0.0530075 |
| TXNRD1 | thioredoxin reductase 1 | -0.0504862 |
| COL1A1 | collagen, type I, alpha 1 | -0.050361 |
| TPM4 | tropomyosin 4 | -0.0502408 |
| ANXA2 | annexin A2 | -0.0496355 |
| HLA-B | major histocompatibility complex, class I, B | -0.0495492 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0486246 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.048161 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.046877 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0461004 |
| SMAD3 | SMAD family member 3 | -0.0450687 |
| MKI67 | marker of proliferation Ki-67 | -0.0441845 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0436365 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0433119 |
| FLNA | filamin A, alpha | -0.0431512 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0424691 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0422845 |
| RAI14 | retinoic acid induced 14 | -0.0420408 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0406017 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0400635 |
| RNF213 | ring finger protein 213 | -0.0394337 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0391614 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0389429 |
| MT2A | metallothionein 2A | -0.0389255 |
| GNAS | GNAS complex locus | -0.037438 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0369099 |
| CALU | calumenin | -0.0367424 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0358996 |
| RRBP1 | ribosome binding protein 1 | -0.0352642 |
| RPS3 | ribosomal protein S3 | -0.0352 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0351492 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0349521 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0349499 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0347273 |
| POTEF | POTE ankyrin domain family, member F | -0.0345271 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0345179 |
| TUBB | tubulin, beta class I | -0.0344954 |
| FOXP1 | forkhead box P1 | -0.0335748 |
| QKI | QKI, KH domain containing, RNA binding | -0.0328816 |
| RPL23 | ribosomal protein L23 | -0.032772 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0325042 |
| RIGI | RNA sensor RIG-I | -0.0315185 |
| RUNX2 | runt-related transcription factor 2 | -0.0313123 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0313048 |
| FTL | ferritin, light polypeptide | -0.0311949 |
| TENM2 | teneurin transmembrane protein 2 | -0.031055 |
| FRMD5 | FERM domain containing 5 | -0.0306589 |
| UBC | ubiquitin C | -0.0306273 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0296219 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0295012 |
| CAVIN1 | caveolae associated protein 1 | -0.029492 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0294411 |
| SDC4 | syndecan 4 | -0.0292899 |
| TNNC1 | troponin C type 1 (slow) | -0.0290787 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0288596 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0284544 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0283091 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0282741 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0282409 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0278602 |
| RPL35A | ribosomal protein L35a | -0.0277247 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0274968 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0274453 |
| SLC38A1 | solute carrier family 38, member 1 | -0.027355 |
| DST | dystonin | -0.0273412 |
| THOC2 | THO complex 2 | -0.0271646 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0268987 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0267759 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0266528 |
| IER3 | immediate early response 3 | -0.0266506 |
| ATXN1 | ataxin 1 | -0.0265781 |
| HDLBP | high density lipoprotein binding protein | -0.0265435 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0264657 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.026444 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0263837 |
| CEP112 | centrosomal protein 112kDa | -0.0262329 |
| XAF1 | XIAP associated factor 1 | -0.0262321 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0258551 |
| CENPF | centromere protein F, 350/400kDa | -0.0257991 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0256569 |
