| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.160391 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.138247 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.122684 |
| NDRG1 | N-myc downstream regulated 1 | 0.0979 |
| FAM13A | family with sequence similarity 13, member A | 0.0884709 |
| EFNA5 | ephrin-A5 | 0.0808931 |
| CD44 | CD44 molecule (Indian blood group) | 0.0803177 |
| GOLGA4 | golgin A4 | 0.0778588 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0755895 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.072846 |
| CALR | calreticulin | 0.0674436 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.062174 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0610895 |
| HDLBP | high density lipoprotein binding protein | 0.0599622 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0581129 |
| COG5 | component of oligomeric golgi complex 5 | 0.0557119 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.055515 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0545889 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.053691 |
| GLG1 | golgi glycoprotein 1 | 0.0534832 |
| MORF4L2 | mortality factor 4 like 2 | 0.0528556 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.052253 |
| PGK1 | phosphoglycerate kinase 1 | 0.0518901 |
| AUTS2 | autism susceptibility candidate 2 | 0.0490505 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0486729 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0473042 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.047175 |
| EGFR | epidermal growth factor receptor | 0.0461578 |
| NF1 | neurofibromin 1 | 0.0450296 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0447944 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0447307 |
| NOP58 | NOP58 ribonucleoprotein | 0.0443208 |
| PRELID2 | PRELI domain containing 2 | 0.0438479 |
| SOCS5 | suppressor of cytokine signaling 5 | 0.0434459 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0432135 |
| RND3 | Rho family GTPase 3 | 0.0431341 |
| CANX | calnexin | 0.0428825 |
| CLMP | CXADR-like membrane protein | 0.0427892 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0427808 |
| RNF145 | ring finger protein 145 | 0.0426258 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0413252 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0411331 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.041018 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0407624 |
| PGM3 | phosphoglucomutase 3 | 0.04068 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.039615 |
| ATP13A3 | ATPase type 13A3 | 0.0393719 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0392753 |
| TMF1 | TATA element modulatory factor 1 | 0.0390098 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0388415 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.038613 |
| VEGFC | vascular endothelial growth factor C | 0.038285 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0380987 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0374082 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0373939 |
| NMT1 | N-myristoyltransferase 1 | 0.0371859 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0371191 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0366956 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0363853 |
| ARRDC3 | arrestin domain containing 3 | 0.0363346 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0361234 |
| CADM1 | cell adhesion molecule 1 | 0.0357214 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0353956 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0351064 |
| SEC24D | SEC24 family member D | 0.0349784 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0344873 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0343811 |
| FAM13B | family with sequence similarity 13, member B | 0.0341033 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0340169 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0340166 |
| SMYD3 | SET and MYND domain containing 3 | 0.0339006 |
| ABI1 | abl-interactor 1 | 0.0338718 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0336124 |
| VEGFA | vascular endothelial growth factor A | 0.0327899 |
| FTL | ferritin, light polypeptide | 0.0327307 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0325509 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0316626 |
| JMJD1C | jumonji domain containing 1C | 0.0316163 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.031566 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0314437 |
| PTGES2 | prostaglandin E synthase 2 | 0.0312492 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0312445 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0312347 |
| MED13L | mediator complex subunit 13-like | 0.0310989 |
| CD109 | CD109 molecule | 0.0310597 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0309605 |
| INSIG2 | insulin induced gene 2 | 0.0307266 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0304894 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0300239 |
| POM121 | POM121 transmembrane nucleoporin | 0.030013 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0299134 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0298969 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0295908 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0294769 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.029454 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0291718 |
| RB1 | retinoblastoma 1 | 0.028864 |
| RRBP1 | ribosome binding protein 1 | 0.028694 |
| SRP54 | signal recognition particle 54kDa | 0.0286714 |
| PCNX1 | pecanex 1 | 0.0285784 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.187023 |
| HLA-B | major histocompatibility complex, class I, B | -0.128636 |
| MT2A | metallothionein 2A | -0.115707 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0811271 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0578108 |
| TMSB10 | thymosin beta 10 | -0.0527638 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0512985 |
| CALU | calumenin | -0.0510422 |
| RPLP1 | ribosomal protein, large, P1 | -0.0507278 |
| RUNX1 | runt-related transcription factor 1 | -0.0491638 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0467197 |
| LOXL2 | lysyl oxidase-like 2 | -0.04638 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0436174 |
| FAT1 | FAT atypical cadherin 1 | -0.0433152 |
| COL1A2 | collagen, type I, alpha 2 | -0.0431139 |
| MYO10 | myosin X | -0.0426354 |
| SMAD3 | SMAD family member 3 | -0.0420983 |
| CDK6 | cyclin-dependent kinase 6 | -0.0415486 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0414946 |
| ACTG1 | actin gamma 1 | -0.0412944 |
| IL6 | interleukin 6 | -0.0412559 |
| COL1A1 | collagen, type I, alpha 1 | -0.040049 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0399895 |
| USP34 | ubiquitin specific peptidase 34 | -0.0396359 |
| EGR1 | early growth response 1 | -0.0390378 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0389685 |
| INHBA | inhibin, beta A | -0.0385931 |
| UBC | ubiquitin C | -0.0382118 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0368775 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0366919 |
| FHIT | fragile histidine triad | -0.0366533 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0366407 |
| RPL35A | ribosomal protein L35a | -0.0362932 |
| SRPK2 | SRSF protein kinase 2 | -0.0362776 |
| IL6ST | interleukin 6 signal transducer | -0.036222 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0359982 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0355051 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0347084 |
| SNX6 | sorting nexin 6 | -0.0345807 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0342114 |
| CEP290 | centrosomal protein 290kDa | -0.0339281 |
| RPL23 | ribosomal protein L23 | -0.0334198 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0333391 |
| RPL27A | ribosomal protein L27a | -0.0325796 |
| RPS19 | ribosomal protein S19 | -0.0324139 |
| RASAL2 | RAS protein activator like 2 | -0.0323684 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0315425 |
| STC1 | stanniocalcin 1 | -0.0314268 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0311798 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0307934 |
| ARF4 | ADP-ribosylation factor 4 | -0.0306418 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0300539 |
| TCF12 | transcription factor 12 | -0.0296834 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0290901 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0290016 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.028959 |
| RAI14 | retinoic acid induced 14 | -0.0286989 |
| RPL36 | ribosomal protein L36 | -0.0285216 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0283704 |
| WTAP | Wilms tumor 1 associated protein | -0.0282178 |
| GLIS3 | GLIS family zinc finger 3 | -0.027879 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0277998 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0277403 |
| PARD3 | par-3 family cell polarity regulator | -0.0277243 |
| HLA-C | major histocompatibility complex, class I, C | -0.0277118 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0276294 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.027564 |
| PRSS23 | protease, serine, 23 | -0.0274651 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | -0.0273792 |
| RPS6 | ribosomal protein S6 | -0.0273013 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.027195 |
| LOX | lysyl oxidase | -0.0268433 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0267527 |
| GPC6 | glypican 6 | -0.0264614 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0260698 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0258696 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0258645 |
| QKI | QKI, KH domain containing, RNA binding | -0.0257391 |
| FN1 | fibronectin 1 | -0.0257115 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0256558 |
| RPL31 | ribosomal protein L31 | -0.0256094 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.0254057 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0253516 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.025338 |
| LMO7 | LIM domain 7 | -0.0252579 |
| IRF1 | interferon regulatory factor 1 | -0.0250252 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0248642 |
| TUBA1C | tubulin, alpha 1c | -0.0247018 |
| RPL37 | ribosomal protein L37 | -0.0246818 |
| CALD1 | caldesmon 1 | -0.0246736 |
| FOSL1 | FOS-like antigen 1 | -0.0245435 |
| GSN | gelsolin | -0.0244659 |
| C1R | complement component 1, r subcomponent | -0.024438 |
| UTRN | utrophin | -0.0241137 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0240831 |
| COL6A1 | collagen, type VI, alpha 1 | -0.023994 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0239747 |
| RPS4X | ribosomal protein S4, X-linked | -0.0239688 |
| CD63 | CD63 molecule | -0.0239076 |
| ATN1 | atrophin 1 | -0.0236748 |
