| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.105972 |
| CD44 | CD44 molecule (Indian blood group) | 0.0951329 |
| PKM | pyruvate kinase, muscle | 0.0896883 |
| POTEF | POTE ankyrin domain family, member F | 0.0774801 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0741226 |
| ERBIN | erbb2 interacting protein | 0.0717238 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0663662 |
| ATM | ATM serine/threonine kinase | 0.0633663 |
| TPI1 | triosephosphate isomerase 1 | 0.0624291 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0620235 |
| SET | SET nuclear proto-oncogene | 0.0607937 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0606691 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0595182 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0591211 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0588111 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.058642 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0581814 |
| HMGA2 | high mobility group AT-hook 2 | 0.0573754 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0551306 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0536634 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0536383 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0532748 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0525177 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0484547 |
| PRR16 | proline rich 16 | 0.0463096 |
| PYGL | phosphorylase, glycogen, liver | 0.0455441 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0455095 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0453323 |
| FLNB | filamin B, beta | 0.0445917 |
| ATXN1 | ataxin 1 | 0.0436098 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0433835 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0433782 |
| FTL | ferritin, light polypeptide | 0.0429844 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0428483 |
| PTK2 | protein tyrosine kinase 2 | 0.0424461 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0413439 |
| ZNF609 | zinc finger protein 609 | 0.040884 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.040798 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.040445 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0403933 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.039839 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.039483 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0388501 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.038607 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0385819 |
| MSN | moesin | 0.038243 |
| INTS6 | integrator complex subunit 6 | 0.0379012 |
| PRKCA | protein kinase C, alpha | 0.0378271 |
| KLC1 | kinesin light chain 1 | 0.0376431 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.03751 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0374423 |
| RBM39 | RNA binding motif protein 39 | 0.0373418 |
| ATP13A3 | ATPase type 13A3 | 0.0373036 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0370257 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0364175 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.035538 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0353951 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0345245 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0343475 |
| SPNS1 | spinster homolog 1 (Drosophila) | 0.0341964 |
| PHF21A | PHD finger protein 21A | 0.0339212 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0338988 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0331173 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0320388 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0314576 |
| TAOK1 | TAO kinase 1 | 0.0314507 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0310979 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0309817 |
| FOXO3 | forkhead box O3 | 0.0308916 |
| MED13L | mediator complex subunit 13-like | 0.0303219 |
| ATXN2 | ataxin 2 | 0.0302525 |
| LDHA | lactate dehydrogenase A | 0.0302208 |
| TBC1D23 | TBC1 domain family, member 23 | 0.030218 |
| RNF217 | ring finger protein 217 | 0.0294804 |
| NGLY1 | N-glycanase 1 | 0.0294761 |
| TPM3 | tropomyosin 3 | 0.0293354 |
| RPS12 | ribosomal protein S12 | 0.0292155 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.028871 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.028867 |
| PCED1B | PC-esterase domain containing 1B | 0.0288361 |
| PHF20 | PHD finger protein 20 | 0.0288171 |
| FMNL2 | formin-like 2 | 0.028814 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0287758 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0286901 |
| RBM6 | RNA binding motif protein 6 | 0.0281405 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0278313 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0277224 |
| NLK | nemo-like kinase | 0.0276214 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0275587 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0275466 |
| ANGPTL4 | angiopoietin-like 4 | 0.0274624 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0274144 |
| ENO1 | enolase 1, (alpha) | 0.0273994 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0272839 |
| STK24 | serine/threonine kinase 24 | 0.0269941 |
| PODXL | podocalyxin-like | 0.0269148 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0266646 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.026628 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0264243 |
| MRTFA | myocardin related transcription factor A | 0.0263763 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMYD3 | SET and MYND domain containing 3 | -0.057857 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0561779 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0524033 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0461657 |
| H3-3B | H3.3 histone B | -0.0441397 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0419294 |
| OSMR | oncostatin M receptor | -0.0418835 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0383951 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.038137 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0377537 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0371123 |
| ANKRD12 | ankyrin repeat domain 12 | -0.03708 |
| CENPF | centromere protein F, 350/400kDa | -0.0357638 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0356861 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0337118 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0331036 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0326183 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0322986 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0303016 |
| MT2A | metallothionein 2A | -0.029756 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0291778 |
| JMJD1C | jumonji domain containing 1C | -0.0289492 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0288412 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0287842 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | -0.0286985 |
| RPL35A | ribosomal protein L35a | -0.0286777 |
| DIAPH3 | diaphanous-related formin 3 | -0.0278588 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0277437 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0275008 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0275005 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0273999 |
| ATRN | attractin | -0.0273081 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0266103 |
| KIAA1328 | KIAA1328 | -0.0264165 |
| TMSB10 | thymosin beta 10 | -0.0263419 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0261736 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0261622 |
| RPLP0 | ribosomal protein, large, P0 | -0.0259456 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0259171 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0258416 |
| RPL35 | ribosomal protein L35 | -0.0258164 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0258115 |
| MAP1B | microtubule-associated protein 1B | -0.0256972 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0254214 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0246612 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0243097 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0238478 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0237924 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0237791 |
| ZNF267 | zinc finger protein 267 | -0.0236417 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.02351 |
| RANBP17 | RAN binding protein 17 | -0.0233944 |
| GNAS | GNAS complex locus | -0.0233057 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0233041 |
| TPX2 | TPX2, microtubule-associated | -0.0232875 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0231877 |
| IER3 | immediate early response 3 | -0.0226804 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0226546 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0226486 |
| WDR45B | WD repeat domain 45B | -0.022639 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0224652 |
| SF1 | splicing factor 1 | -0.0223471 |
| MKI67 | marker of proliferation Ki-67 | -0.0221867 |
| CENPP | centromere protein P | -0.0220888 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.022022 |
| RBM33 | RNA binding motif protein 33 | -0.0220215 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0220196 |
| PRR11 | proline rich 11 | -0.021907 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0214388 |
| FUS | FUS RNA binding protein | -0.0212129 |
| ZFR | zinc finger RNA binding protein | -0.021194 |
| RPL11 | ribosomal protein L11 | -0.0209131 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0209042 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | -0.0208705 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0208054 |
| EGR1 | early growth response 1 | -0.0208004 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0207486 |
| RPL30 | ribosomal protein L30 | -0.0206007 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0205182 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0204981 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0203767 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0203579 |
| BSG | basigin (Ok blood group) | -0.0202756 |
| KIF18B | kinesin family member 18B | -0.0202561 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.020227 |
| CCPG1 | cell cycle progression 1 | -0.0201957 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0201366 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0200623 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0200257 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0199216 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0198931 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.019838 |
| DPP8 | dipeptidyl-peptidase 8 | -0.0198212 |
| SERPINA2 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) | -0.0197825 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0197674 |
| IL6ST | interleukin 6 signal transducer | -0.0197013 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0195401 |
| STRBP | spermatid perinuclear RNA binding protein | -0.0194803 |
| FAM120A | family with sequence similarity 120A | -0.0193923 |
| ACTG1 | actin gamma 1 | -0.0193385 |
