| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Valdecoxib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Valdecoxib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.15076 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.118483 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.110104 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0782532 |
| TXNIP | thioredoxin interacting protein | 0.0700878 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0643134 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0582048 |
| RNF145 | ring finger protein 145 | 0.0554459 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.052906 |
| SUCO | SUN domain containing ossification factor | 0.0512736 |
| TPR | translocated promoter region, nuclear basket protein | 0.0507208 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0491227 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0467254 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0465162 |
| GOLGA4 | golgin A4 | 0.0461104 |
| AHR | aryl hydrocarbon receptor | 0.0449006 |
| CD44 | CD44 molecule (Indian blood group) | 0.0448526 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.042892 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0428523 |
| MKI67 | marker of proliferation Ki-67 | 0.0401254 |
| SMOX | spermine oxidase | 0.040011 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0398892 |
| CENPF | centromere protein F, 350/400kDa | 0.0389704 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0389038 |
| WDR26 | WD repeat domain 26 | 0.0379044 |
| ETNK1 | ethanolamine kinase 1 | 0.0377287 |
| FNDC3B | fibronectin type III domain containing 3B | 0.037518 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0371851 |
| YME1L1 | YME1-like 1 ATPase | 0.0370944 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0370323 |
| CD109 | CD109 molecule | 0.0367069 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0366162 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0363905 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0359899 |
| PELO | pelota homolog (Drosophila) | 0.0353645 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0353051 |
| NEK7 | NIMA-related kinase 7 | 0.0341719 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0331867 |
| HMGB3 | high mobility group box 3 | 0.0329342 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.03246 |
| KSR1 | kinase suppressor of ras 1 | 0.0324205 |
| VMP1 | vacuole membrane protein 1 | 0.0319831 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0318174 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0312873 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0311859 |
| RBM25 | RNA binding motif protein 25 | 0.0308522 |
| ADD3 | adducin 3 (gamma) | 0.030837 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0303601 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0302875 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0298802 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0298071 |
| NUP58 | nucleoporin 58 | 0.0297606 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0297343 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.02953 |
| OGA | O-GlcNAcase | 0.0294341 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0289977 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0289703 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0285116 |
| CDC73 | cell division cycle 73 | 0.0281843 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0281 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0279792 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0279257 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0278198 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0277518 |
| CEP350 | centrosomal protein 350kDa | 0.0277294 |
| RUNX2 | runt-related transcription factor 2 | 0.0274607 |
| RANBP2 | RAN binding protein 2 | 0.0273415 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0271439 |
| EREG | epiregulin | 0.0268481 |
| MIS18BP1 | MIS18 binding protein 1 | 0.026789 |
| B2M | beta-2-microglobulin | 0.026665 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0260903 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0260348 |
| HOMER2 | homer scaffolding protein 2 | 0.0259684 |
| FNBP1 | formin binding protein 1 | 0.0259655 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0256903 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0253438 |
| TMF1 | TATA element modulatory factor 1 | 0.0253079 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0252779 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0251212 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0251067 |
| RO60 | Ro60, Y RNA binding protein | 0.0250618 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0248166 |
| ATL2 | atlastin GTPase 2 | 0.024673 |
| COPA | coatomer protein complex, subunit alpha | 0.0244048 |
| RNF24 | ring finger protein 24 | 0.024249 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0241803 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0240801 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0239333 |
| PGK1 | phosphoglycerate kinase 1 | 0.0238074 |
| CACUL1 | CDK2-associated, cullin domain 1 | 0.0236474 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0234159 |
| ERBIN | erbb2 interacting protein | 0.0233673 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.023255 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0232381 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0230256 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0229424 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0225934 |
| WDR45B | WD repeat domain 45B | 0.0225253 |
| COG5 | component of oligomeric golgi complex 5 | 0.0225078 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.34709 |
| FN1 | fibronectin 1 | -0.345374 |
| HMGA2 | high mobility group AT-hook 2 | -0.174398 |
| ASPH | aspartate beta-hydroxylase | -0.104412 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0967522 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0865856 |
| TMSB10 | thymosin beta 10 | -0.0754522 |
| SYT1 | synaptotagmin I | -0.0731824 |
| NDRG1 | N-myc downstream regulated 1 | -0.0730787 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0603645 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0592088 |
| SQSTM1 | sequestosome 1 | -0.0586751 |
| HLA-B | major histocompatibility complex, class I, B | -0.055755 |
| STC2 | stanniocalcin 2 | -0.0526064 |
| ACTG1 | actin gamma 1 | -0.0500381 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0490182 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.048059 |
| GLIS3 | GLIS family zinc finger 3 | -0.0468552 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0456318 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.044608 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.044204 |
| AEBP2 | AE binding protein 2 | -0.042321 |
| INTS6 | integrator complex subunit 6 | -0.0422758 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.041236 |
| EFNA5 | ephrin-A5 | -0.0410741 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0410282 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.040725 |
| PTMA | prothymosin, alpha | -0.0406017 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0392359 |
| RAI14 | retinoic acid induced 14 | -0.0392072 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.038731 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0370521 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0365892 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.035082 |
| FTL | ferritin, light polypeptide | -0.0337359 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0332259 |
| SLC35F3 | solute carrier family 35, member F3 | -0.03293 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.032913 |
| TENM4 | teneurin transmembrane protein 4 | -0.0326551 |
| LOXL2 | lysyl oxidase-like 2 | -0.0325062 |
| RNF213 | ring finger protein 213 | -0.0316499 |
| CUX1 | cut-like homeobox 1 | -0.0316175 |
| PRKCA | protein kinase C, alpha | -0.0315595 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0307462 |
| CADM1 | cell adhesion molecule 1 | -0.0306021 |
| MAP1B | microtubule-associated protein 1B | -0.0305554 |
| LMNA | lamin A/C | -0.0302931 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0293316 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0290676 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0289526 |
| IER3 | immediate early response 3 | -0.0287431 |
| RACK1 | receptor for activated C kinase 1 | -0.0283184 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0276371 |
| LRRC23 | leucine rich repeat containing 23 | -0.0270764 |
| ABR | active BCR-related | -0.0269408 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0266653 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0264816 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0263272 |
| TMSB4X | thymosin beta 4, X-linked | -0.0262834 |
| AHNAK | AHNAK nucleoprotein | -0.0262773 |
| RANBP17 | RAN binding protein 17 | -0.0261082 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0258442 |
| RASAL2 | RAS protein activator like 2 | -0.0257331 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0257053 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0256781 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0255137 |
| MCL1 | myeloid cell leukemia 1 | -0.0254484 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0253843 |
| RIGI | RNA sensor RIG-I | -0.0249907 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0249885 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0246786 |
| MYOF | myoferlin | -0.0245565 |
| IFI44L | interferon-induced protein 44-like | -0.0242604 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0242372 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0239539 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0236755 |
| TNS3 | tensin 3 | -0.0232922 |
| S100A6 | S100 calcium binding protein A6 | -0.0232228 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0231191 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0226443 |
| FLNA | filamin A, alpha | -0.0223314 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0223083 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0219642 |
| RAD51B | RAD51 paralog B | -0.0218556 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0217934 |
| S100A10 | S100 calcium binding protein A10 | -0.021775 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0216526 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0215694 |
| HMGA1 | high mobility group AT-hook 1 | -0.0213827 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0212124 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0211451 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0210943 |
| EMP1 | epithelial membrane protein 1 | -0.0209653 |
| EGR1 | early growth response 1 | -0.0208883 |
| TUFT1 | tuftelin 1 | -0.0207891 |
| ACTN4 | actinin, alpha 4 | -0.0207867 |
| NBEA | neurobeachin | -0.0206738 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0206602 |
| ATXN1 | ataxin 1 | -0.0206102 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0201568 |
