Validated targets of C-MYC transcriptional repression Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/6bbdafa6-6196-11e5-8ac5-06603eb7f303
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Genes

62 proteins participating in the Validated targets of C-MYC transcriptional repression pathway from the PID Pathways dataset.

Symbol Name
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
BCL2 B-cell CLL/lymphoma 2
BRCA1 breast cancer 1, early onset
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFLAR CASP8 and FADD-like apoptosis regulator
CLU clusterin
COL1A2 collagen, type I, alpha 2
CREB1 cAMP responsive element binding protein 1
CSDE1 cold shock domain containing E1, RNA-binding
DDIT3 DNA-damage-inducible transcript 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNTT DNA nucleotidylexotransferase
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
FOXO3 forkhead box O3
FTH1 ferritin, heavy polypeptide 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GFI1 growth factor independent 1 transcription repressor
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IRF8 interferon regulatory factor 8
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
LGALS1 lectin, galactoside-binding, soluble, 1
MAX MYC associated factor X
MXD4 MAX dimerization protein 4
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NFYA nuclear transcription factor Y, alpha
NFYB nuclear transcription factor Y, beta
NFYC nuclear transcription factor Y, gamma
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
RBL1 retinoblastoma-like 1
S100A7 S100 calcium binding protein A7
SFRP1 secreted frizzled-related protein 1
SFXN3 sideroflexin 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SP1 Sp1 transcription factor
SPI1 Spi-1 proto-oncogene
TBP TATA box binding protein
TJP2 tight junction protein 2
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TMEM126A transmembrane protein 126A
TSC2 tuberous sclerosis 2
WNT5A wingless-type MMTV integration site family, member 5A
ZBTB17 zinc finger and BTB domain containing 17
ZFP36L1 ZFP36 ring finger protein-like 1