| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vandetanib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.235388 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0629392 |
| HELZ | helicase with zinc finger | 0.0625597 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0610451 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0587553 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0540454 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0494054 |
| WDR45B | WD repeat domain 45B | 0.0474809 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0414628 |
| XPO1 | exportin 1 | 0.0410991 |
| FAM13A | family with sequence similarity 13, member A | 0.0401299 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0388679 |
| PCBP2 | poly(rC) binding protein 2 | 0.0372982 |
| ZNF292 | zinc finger protein 292 | 0.037276 |
| DTNA | dystrobrevin, alpha | 0.035941 |
| ANXA2 | annexin A2 | 0.0356226 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0346327 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0345394 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0341875 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.033674 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.032904 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0328805 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0316214 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0309072 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.030592 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0304431 |
| RTN4 | reticulon 4 | 0.02989 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0295164 |
| RNF145 | ring finger protein 145 | 0.0294182 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0293744 |
| ARF4 | ADP-ribosylation factor 4 | 0.0272248 |
| GDF15 | growth differentiation factor 15 | 0.0269291 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0268198 |
| ZNF638 | zinc finger protein 638 | 0.0268187 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0266892 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0263363 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0257774 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0257589 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0257138 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0256566 |
| PCM1 | pericentriolar material 1 | 0.0253801 |
| ARRDC3 | arrestin domain containing 3 | 0.0251994 |
| PGK1 | phosphoglycerate kinase 1 | 0.0251336 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0250107 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0245611 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0244495 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0243569 |
| CLTC | clathrin, heavy chain (Hc) | 0.0240563 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.023888 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.023836 |
| ANO6 | anoctamin 6 | 0.0235678 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0233707 |
| TCF12 | transcription factor 12 | 0.0232501 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0232439 |
| LPIN1 | lipin 1 | 0.0226261 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0225139 |
| MED13 | mediator complex subunit 13 | 0.0224644 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0224539 |
| PLAT | plasminogen activator, tissue | 0.0224523 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.022421 |
| RNF111 | ring finger protein 111 | 0.0222741 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0222307 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0222059 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0221981 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0221863 |
| SAFB | scaffold attachment factor B | 0.0221361 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.022125 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0221201 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0220331 |
| ENAH | enabled homolog (Drosophila) | 0.0220013 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0218699 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0218344 |
| NAA25 | N(alpha)-acetyltransferase 25, NatB auxiliary subunit | 0.0216915 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0216616 |
| S100A6 | S100 calcium binding protein A6 | 0.0215931 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.02151 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0214079 |
| CEP350 | centrosomal protein 350kDa | 0.0213724 |
| LONP2 | lon peptidase 2, peroxisomal | 0.0213059 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.02094 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0209311 |
| PTEN | phosphatase and tensin homolog | 0.0207641 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0206954 |
| GLG1 | golgi glycoprotein 1 | 0.0205435 |
| MDM4 | MDM4, p53 regulator | 0.020165 |
| WDR43 | WD repeat domain 43 | 0.020154 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0200538 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0200527 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0197267 |
| POTEF | POTE ankyrin domain family, member F | 0.0196579 |
| BBX | bobby sox homolog (Drosophila) | 0.0195471 |
| DIAPH2 | diaphanous-related formin 2 | 0.0195419 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.019356 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0193147 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0192904 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0192581 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.019128 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0191116 |
| EPHA3 | EPH receptor A3 | 0.019042 |
| WDR3 | WD repeat domain 3 | 0.0189696 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | -0.150904 |
| VCL | vinculin | -0.0843318 |
| NRG1 | neuregulin 1 | -0.0811221 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0798639 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0689123 |
| IGF2 | insulin-like growth factor 2 | -0.0686912 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0678465 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0656714 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0655409 |
| TLE4 | transducin-like enhancer of split 4 | -0.0625273 |
| SYT1 | synaptotagmin I | -0.0611033 |
| KLHL13 | kelch-like family member 13 | -0.0603936 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0598031 |
| SP100 | SP100 nuclear antigen | -0.0583107 |
| RPL23 | ribosomal protein L23 | -0.0579426 |
| RNF213 | ring finger protein 213 | -0.057794 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0510462 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0499264 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0493554 |
| TMSB10 | thymosin beta 10 | -0.0476347 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0476199 |
| MEIS2 | Meis homeobox 2 | -0.046968 |
| FMN1 | formin 1 | -0.0455424 |
| FRMD4A | FERM domain containing 4A | -0.0440961 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0438926 |
| RPLP1 | ribosomal protein, large, P1 | -0.0438269 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0431556 |
| RPS19 | ribosomal protein S19 | -0.0415348 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0412728 |
| RIGI | RNA sensor RIG-I | -0.0409172 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0397034 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0395902 |
| FAM107B | family with sequence similarity 107, member B | -0.0381226 |
| RPL19 | ribosomal protein L19 | -0.0376442 |
| ZNF804A | zinc finger protein 804A | -0.0374673 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0372994 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0370093 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0370089 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0365759 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0351638 |
| COL1A1 | collagen, type I, alpha 1 | -0.0341741 |
| RPL35A | ribosomal protein L35a | -0.033799 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0337798 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0334757 |
| RPS6 | ribosomal protein S6 | -0.0328951 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0324695 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0322726 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0322598 |
| TRIB2 | tribbles pseudokinase 2 | -0.0320334 |
| MYO9A | myosin IXA | -0.0320006 |
| RPS27 | ribosomal protein S27 | -0.0318075 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0316818 |
| AOPEP | aminopeptidase O (putative) | -0.0316539 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.031475 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0310218 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0309974 |
| PDE10A | phosphodiesterase 10A | -0.0309288 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0303814 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0295991 |
| NRP1 | neuropilin 1 | -0.0295948 |
| KLF6 | Kruppel-like factor 6 | -0.0295291 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0294383 |
| MX2 | MX dynamin-like GTPase 2 | -0.0292803 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.028927 |
| RPL36 | ribosomal protein L36 | -0.0286996 |
| RAB7A | RAB7A, member RAS oncogene family | -0.028689 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0286824 |
| DNM3 | dynamin 3 | -0.0285069 |
| PRKCA | protein kinase C, alpha | -0.0283068 |
| EGFR | epidermal growth factor receptor | -0.0275745 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0275387 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0275107 |
| HLA-B | major histocompatibility complex, class I, B | -0.0274936 |
| CUL1 | cullin 1 | -0.0274069 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0269239 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0265227 |
| GLCCI1 | glucocorticoid induced 1 | -0.026472 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.026082 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0257473 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0256564 |
| IER3 | immediate early response 3 | -0.025426 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0253905 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0250796 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0250462 |
| RBM39 | RNA binding motif protein 39 | -0.0247812 |
| EGR1 | early growth response 1 | -0.0247466 |
| AEBP2 | AE binding protein 2 | -0.0246148 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0244794 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0244486 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0242973 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0242339 |
| LIMA1 | LIM domain and actin binding 1 | -0.0241988 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0241536 |
| CALD1 | caldesmon 1 | -0.0241488 |
| COL3A1 | collagen, type III, alpha 1 | -0.0240798 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0239113 |
| IRS1 | insulin receptor substrate 1 | -0.023584 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0235289 |
| STXBP4 | syntaxin binding protein 4 | -0.0235233 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0234219 |
