| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vandetanib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MACC1 | metastasis associated in colon cancer 1 | 0.0430321 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0386911 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0278288 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0211406 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0192434 |
| PLIN2 | perilipin 2 | 0.0191142 |
| ABHD2 | abhydrolase domain containing 2 | 0.0188485 |
| RNF149 | ring finger protein 149 | 0.0172494 |
| MLEC | malectin | 0.0169374 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0161865 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0157403 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0154741 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0154082 |
| TMC5 | transmembrane channel-like 5 | 0.0147363 |
| MXI1 | MAX interactor 1, dimerization protein | 0.014624 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0142532 |
| EREG | epiregulin | 0.0141523 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0138629 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0138612 |
| OCLN | occludin | 0.0133512 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0125487 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0123703 |
| TPM4 | tropomyosin 4 | 0.0122498 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0121982 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0121791 |
| CDHR2 | cadherin-related family member 2 | 0.0119738 |
| SFXN1 | sideroflexin 1 | 0.0119422 |
| B2M | beta-2-microglobulin | 0.0118908 |
| PTEN | phosphatase and tensin homolog | 0.011798 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0117033 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0116722 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 0.0116415 |
| AREG | amphiregulin | 0.0115909 |
| PGK1 | phosphoglycerate kinase 1 | 0.0115131 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0114681 |
| CLTC | clathrin, heavy chain (Hc) | 0.0114173 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0111311 |
| ZNF395 | zinc finger protein 395 | 0.0107885 |
| ZNF146 | zinc finger protein 146 | 0.0107041 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0106407 |
| KIF16B | kinesin family member 16B | 0.0106357 |
| BRCA1 | breast cancer 1, early onset | 0.0105858 |
| NPSR1 | neuropeptide S receptor 1 | 0.0104953 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0104172 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0102546 |
| EFHD2 | EF-hand domain family, member D2 | 0.0101055 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.00999191 |
| GOLGA2 | golgin A2 | 0.00983859 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.00983168 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | 0.00982931 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00978141 |
| CNOT11 | CCR4-NOT transcription complex, subunit 11 | 0.00964594 |
| UBXN7 | UBX domain protein 7 | 0.00963786 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00957493 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.00954654 |
| GOSR1 | golgi SNAP receptor complex member 1 | 0.00941534 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.00939905 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00939838 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.00931787 |
| SRP9 | signal recognition particle 9kDa | 0.00930616 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.00930547 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00929792 |
| DIABLO | diablo, IAP-binding mitochondrial protein | 0.00927619 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.00927597 |
| RAB27A | RAB27A, member RAS oncogene family | 0.00924849 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.00924609 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00919199 |
| CTSD | cathepsin D | 0.00913159 |
| MYO1E | myosin IE | 0.00896278 |
| SPATA6L | spermatogenesis associated 6-like | 0.00889655 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00885427 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.00877393 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.00873996 |
| RLIM | ring finger protein, LIM domain interacting | 0.00863695 |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.00862004 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.00860489 |
| CCNI | cyclin I | 0.008502 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.00845461 |
| ZNF292 | zinc finger protein 292 | 0.00843774 |
| SEC24A | SEC24 family member A | 0.00842205 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00836362 |
| LARP7 | La ribonucleoprotein domain family, member 7 | 0.00835787 |
| KLHL24 | kelch-like family member 24 | 0.00834763 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00833728 |
| FASTKD1 | FAST kinase domains 1 | 0.0083286 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.00830721 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00824959 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | 0.0082131 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00816504 |
| MIGA1 | mitoguardin 1 | 0.00815843 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | 0.00813954 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00810089 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.00808809 |
| HMGN1 | high mobility group nucleosome binding domain 1 | 0.00807195 |
| ERBIN | erbb2 interacting protein | 0.00793195 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.00790284 |
| WASF2 | WAS protein family, member 2 | 0.00789116 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00782721 |
| RAB8A | RAB8A, member RAS oncogene family | 0.00772336 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0076869 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.097783 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0868687 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0828965 |
| MX1 | MX dynamin-like GTPase 1 | -0.0755247 |
| RNF213 | ring finger protein 213 | -0.0752095 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0562079 |
| RUNX1 | runt-related transcription factor 1 | -0.0537179 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0521523 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0504656 |
| MX2 | MX dynamin-like GTPase 2 | -0.0503875 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0486541 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0482179 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0472444 |
| RIGI | RNA sensor RIG-I | -0.0472421 |
| RNF43 | ring finger protein 43 | -0.046993 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0468051 |
| NCKAP5 | NCK-associated protein 5 | -0.0467147 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0443836 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0430117 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.042413 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0406851 |
| RPL23 | ribosomal protein L23 | -0.0402847 |
| PLSCR1 | phospholipid scramblase 1 | -0.0402188 |
| EZR | ezrin | -0.0383436 |
| RRBP1 | ribosome binding protein 1 | -0.037878 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0378267 |
| PKM | pyruvate kinase, muscle | -0.0355253 |
| INTS6 | integrator complex subunit 6 | -0.035324 |
| SQSTM1 | sequestosome 1 | -0.0351071 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0349852 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0337522 |
| MLPH | melanophilin | -0.0332058 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0324054 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0318106 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0316269 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0309677 |
| SP100 | SP100 nuclear antigen | -0.0303557 |
| PHF3 | PHD finger protein 3 | -0.0302126 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0296971 |
| EFNB2 | ephrin-B2 | -0.0282724 |
| AHNAK | AHNAK nucleoprotein | -0.0277663 |
| NF1 | neurofibromin 1 | -0.0274115 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.027342 |
| PRRC2C | proline-rich coiled-coil 2C | -0.026654 |
| ACTN4 | actinin, alpha 4 | -0.0265892 |
| ATP11A | ATPase, class VI, type 11A | -0.026531 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0262341 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0260081 |
| RPL35A | ribosomal protein L35a | -0.025819 |
| ADAR | adenosine deaminase, RNA-specific | -0.0254288 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0254187 |
| RPS27A | ribosomal protein S27a | -0.0251547 |
| XAF1 | XIAP associated factor 1 | -0.0247392 |
| SPATA13 | spermatogenesis associated 13 | -0.0246398 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0244199 |
| APP | amyloid beta (A4) precursor protein | -0.0242885 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0237737 |
| RBM39 | RNA binding motif protein 39 | -0.0236609 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0235511 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0235266 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0234336 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.023356 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0230212 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0228657 |
| IRS2 | insulin receptor substrate 2 | -0.0227887 |
| ATXN1 | ataxin 1 | -0.0226841 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0226084 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.022399 |
| PRKCA | protein kinase C, alpha | -0.0223802 |
| JUN | jun proto-oncogene | -0.0223749 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0220662 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0220011 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0218958 |
| RPS6 | ribosomal protein S6 | -0.0218215 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0217093 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0214 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.021283 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0212673 |
| DSPP | dentin sialophosphoprotein | -0.0210852 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0210366 |
| EPCAM | epithelial cell adhesion molecule | -0.0209964 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.02098 |
| HDAC4 | histone deacetylase 4 | -0.0209677 |
| STK24 | serine/threonine kinase 24 | -0.020967 |
| UBAC2 | UBA domain containing 2 | -0.0207247 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0207196 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0206064 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0205077 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0204655 |
| TMSB10 | thymosin beta 10 | -0.0203564 |
| ZNRF3 | zinc and ring finger 3 | -0.0203374 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0202462 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0202326 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0202143 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0201908 |
| RPS3 | ribosomal protein S3 | -0.020073 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0200529 |
| CALU | calumenin | -0.0198903 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0197243 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0196755 |
