| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vandetanib_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.138048 |
| EREG | epiregulin | 0.0606854 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0489968 |
| PGK1 | phosphoglycerate kinase 1 | 0.0452547 |
| TXNIP | thioredoxin interacting protein | 0.0411577 |
| ENO1 | enolase 1, (alpha) | 0.0367726 |
| WDR45B | WD repeat domain 45B | 0.035953 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0350604 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0342706 |
| GDF15 | growth differentiation factor 15 | 0.0340869 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0326568 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0299656 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0290657 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.028246 |
| RNF145 | ring finger protein 145 | 0.0274784 |
| ANXA1 | annexin A1 | 0.0273091 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0268429 |
| CANX | calnexin | 0.0259777 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0255864 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0252909 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0248739 |
| EXOC1 | exocyst complex component 1 | 0.0238565 |
| EMP1 | epithelial membrane protein 1 | 0.0238397 |
| LDHA | lactate dehydrogenase A | 0.0232782 |
| TFG | TRK-fused gene | 0.0231493 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.022501 |
| PERP | PERP, TP53 apoptosis effector | 0.0217013 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0214479 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0210855 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0209267 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.020813 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0206082 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0204551 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0204075 |
| MLEC | malectin | 0.0203185 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0199651 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0198154 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0196365 |
| S100P | S100 calcium binding protein P | 0.0196159 |
| AREG | amphiregulin | 0.0195507 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0194708 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0192003 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0186951 |
| GOLGA2 | golgin A2 | 0.0185212 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0184482 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.017988 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0178409 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0178237 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0176763 |
| FAM13A | family with sequence similarity 13, member A | 0.0175193 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0172438 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0171974 |
| CALR | calreticulin | 0.0171134 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0170164 |
| COPA | coatomer protein complex, subunit alpha | 0.0170113 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0167393 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0165926 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0165283 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0164488 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0162358 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0158887 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0158064 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0157248 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0154866 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.015406 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0153213 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0152832 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0152828 |
| RPLP0 | ribosomal protein, large, P0 | 0.0152517 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0151876 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0151536 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0148815 |
| PLAUR | plasminogen activator, urokinase receptor | 0.014734 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0144103 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0142808 |
| NUP58 | nucleoporin 58 | 0.014246 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0140507 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0139691 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0138316 |
| ANXA2 | annexin A2 | 0.0136874 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.013681 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.013644 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0135596 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0135478 |
| H2AC6 | H2A clustered histone 6 | 0.013483 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0134158 |
| UBC | ubiquitin C | 0.0132553 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.013229 |
| TMEM59 | transmembrane protein 59 | 0.0130276 |
| ARF4 | ADP-ribosylation factor 4 | 0.0127925 |
| YME1L1 | YME1-like 1 ATPase | 0.0125849 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0125173 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0124748 |
| CCNI | cyclin I | 0.0124343 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0123987 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.012362 |
| TMEM41B | transmembrane protein 41B | 0.0123202 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0123057 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0121978 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0119261 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.189504 |
| NPSR1 | neuropeptide S receptor 1 | -0.14692 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.145211 |
| RPS6 | ribosomal protein S6 | -0.118554 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0939907 |
| GPHN | gephyrin | -0.0879579 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0857941 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0767477 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0730281 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0701069 |
| TNS4 | tensin 4 | -0.0678641 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0656779 |
| FHIT | fragile histidine triad | -0.0655081 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0632012 |
| RPS2 | ribosomal protein S2 | -0.0630759 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0615555 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0611329 |
| SMYD3 | SET and MYND domain containing 3 | -0.060469 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.058082 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0570376 |
| CADPS | Ca++-dependent secretion activator | -0.0551454 |
| FOXP1 | forkhead box P1 | -0.0537855 |
| TRIM2 | tripartite motif containing 2 | -0.0537678 |
| RAD51B | RAD51 paralog B | -0.053666 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0524222 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0506428 |
| PTMA | prothymosin, alpha | -0.0485012 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0484003 |
| VEGFA | vascular endothelial growth factor A | -0.0481548 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0476028 |
| DSPP | dentin sialophosphoprotein | -0.0467511 |
| TMSB10 | thymosin beta 10 | -0.0463874 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0459311 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0458635 |
| NRXN3 | neurexin 3 | -0.045336 |
| ATXN1 | ataxin 1 | -0.0452609 |
| ONECUT3 | one cut homeobox 3 | -0.0448891 |
| RPS8 | ribosomal protein S8 | -0.0445077 |
| MYO1E | myosin IE | -0.0440109 |
| PRELID2 | PRELI domain containing 2 | -0.0438702 |
| RNF43 | ring finger protein 43 | -0.0431349 |
| CD44 | CD44 molecule (Indian blood group) | -0.043003 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0418833 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0412501 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0409991 |
| RPL26 | ribosomal protein L26 | -0.0409563 |
| RPL9 | ribosomal protein L9 | -0.0405343 |
| ACTG1 | actin gamma 1 | -0.040511 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0396885 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0395381 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0392352 |
| TBC1D5 | TBC1 domain family, member 5 | -0.038665 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0375123 |
| NEBL | nebulette | -0.0371078 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0369729 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0367818 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0358751 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0356028 |
| MECOM | MDS1 and EVI1 complex locus | -0.0352601 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0345603 |
| MYO1D | myosin ID | -0.0344628 |
| PRSS3 | protease, serine, 3 | -0.0342856 |
| RPS12 | ribosomal protein S12 | -0.034178 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0325661 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0319894 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0318243 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0317697 |
| ADD3 | adducin 3 (gamma) | -0.0314629 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0312977 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0310655 |
| SH3D19 | SH3 domain containing 19 | -0.0305308 |
| RPL37A | ribosomal protein L37a | -0.0304883 |
| GOLGB1 | golgin B1 | -0.0302286 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0301065 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0300312 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0299024 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.029887 |
| RPLP2 | ribosomal protein, large, P2 | -0.0298114 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.029458 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0294475 |
| RPLP1 | ribosomal protein, large, P1 | -0.029343 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0292374 |
| DSG2 | desmoglein 2 | -0.0290695 |
| RPS19 | ribosomal protein S19 | -0.0289166 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0286685 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0283808 |
| RPL36 | ribosomal protein L36 | -0.0283643 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0282023 |
| EPHB2 | EPH receptor B2 | -0.0275388 |
| PIGR | polymeric immunoglobulin receptor | -0.0274992 |
| RAB10 | RAB10, member RAS oncogene family | -0.0274975 |
| RPL23 | ribosomal protein L23 | -0.0273836 |
| SBF2 | SET binding factor 2 | -0.0273243 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0273109 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0270778 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0270445 |
| EXOC4 | exocyst complex component 4 | -0.0270004 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0269519 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0267899 |
| ABHD2 | abhydrolase domain containing 2 | -0.0266718 |
