| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vandetanib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.138235 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.13036 |
| RAI1 | retinoic acid induced 1 | 0.116895 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.111188 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.110807 |
| CANX | calnexin | 0.10167 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0978165 |
| PTMA | prothymosin, alpha | 0.0920971 |
| PGK1 | phosphoglycerate kinase 1 | 0.0879182 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0878293 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0865709 |
| VIM | vimentin | 0.0864961 |
| TMSB4X | thymosin beta 4, X-linked | 0.0795189 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0749675 |
| DST | dystonin | 0.071091 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0700444 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0697978 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0680378 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0677523 |
| TP63 | tumor protein p63 | 0.0672989 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0662925 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0657958 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0657858 |
| TXNIP | thioredoxin interacting protein | 0.0648647 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0641917 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0641523 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0635367 |
| FNIP1 | folliculin interacting protein 1 | 0.059578 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0576573 |
| XPO1 | exportin 1 | 0.0571211 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0559133 |
| CENPF | centromere protein F, 350/400kDa | 0.0541541 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0534504 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0532804 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0520346 |
| ENO1 | enolase 1, (alpha) | 0.0514135 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0482921 |
| TNS3 | tensin 3 | 0.047964 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0477111 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0475912 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0475126 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0474542 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0471826 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.046772 |
| HLA-B | major histocompatibility complex, class I, B | 0.0466263 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0457993 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0454417 |
| CDK19 | cyclin-dependent kinase 19 | 0.0445561 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0435065 |
| GLG1 | golgi glycoprotein 1 | 0.0431294 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0429367 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0429043 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0409849 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0407484 |
| SPAG9 | sperm associated antigen 9 | 0.0403517 |
| PLK2 | polo-like kinase 2 | 0.0401885 |
| SET | SET nuclear proto-oncogene | 0.0401294 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0398178 |
| PCBP2 | poly(rC) binding protein 2 | 0.0394615 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0393422 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0390889 |
| FMNL2 | formin-like 2 | 0.0388909 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0388294 |
| ATP13A3 | ATPase type 13A3 | 0.0384304 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0382937 |
| ZNF148 | zinc finger protein 148 | 0.0382922 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0378641 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.037151 |
| YEATS2 | YEATS domain containing 2 | 0.0367439 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0366746 |
| MATR3 | matrin 3 | 0.0364717 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0364172 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0357219 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0354791 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0354733 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0349221 |
| APP | amyloid beta (A4) precursor protein | 0.0347985 |
| SRPK2 | SRSF protein kinase 2 | 0.0343646 |
| ARRDC3 | arrestin domain containing 3 | 0.0342906 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0342603 |
| USP34 | ubiquitin specific peptidase 34 | 0.0342407 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0335373 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0328741 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0328625 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.032848 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0326689 |
| SLK | STE20-like kinase | 0.0326176 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0324508 |
| CALR | calreticulin | 0.032277 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0321762 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0319924 |
| CADM2 | cell adhesion molecule 2 | 0.0318527 |
| PLIN2 | perilipin 2 | 0.0318142 |
| ATXN2 | ataxin 2 | 0.0317968 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0317828 |
| PKN2 | protein kinase N2 | 0.0316437 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0315681 |
| PDE10A | phosphodiesterase 10A | 0.031558 |
| OGA | O-GlcNAcase | 0.0314508 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0314001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.194729 |
| TMSB10 | thymosin beta 10 | -0.125254 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0910119 |
| FTL | ferritin, light polypeptide | -0.0687222 |
| RPL35A | ribosomal protein L35a | -0.0638491 |
| EGR1 | early growth response 1 | -0.0421013 |
| RPL23 | ribosomal protein L23 | -0.039106 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0375323 |
| EMP1 | epithelial membrane protein 1 | -0.037409 |
| BRD2 | bromodomain containing 2 | -0.0363838 |
| YBX3 | Y box binding protein 3 | -0.0354401 |
| RPS6 | ribosomal protein S6 | -0.0349774 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0337548 |
| TOP1 | topoisomerase (DNA) I | -0.0315742 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312497 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.031248 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0308576 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0307937 |
| ACTG1 | actin gamma 1 | -0.0305883 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0301214 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0294535 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0288635 |
| RPS2 | ribosomal protein S2 | -0.0284765 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0276701 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.026045 |
| HMGB1 | high mobility group box 1 | -0.024994 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0245842 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0240662 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0236593 |
| SGMS2 | sphingomyelin synthase 2 | -0.0236261 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0232036 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0226268 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0224859 |
| RPL5 | ribosomal protein L5 | -0.0224547 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0209818 |
| PLSCR1 | phospholipid scramblase 1 | -0.0209482 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0199942 |
| SEC61G | Sec61 gamma subunit | -0.019788 |
| YBX1 | Y box binding protein 1 | -0.0194379 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0192036 |
| RPS8 | ribosomal protein S8 | -0.0192026 |
| GNAS | GNAS complex locus | -0.0191205 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0189459 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0188523 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0188522 |
| FUS | FUS RNA binding protein | -0.0188304 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0187527 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0186961 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0186664 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.018553 |
| RPL13A | ribosomal protein L13a | -0.0179092 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0172113 |
| RPL34 | ribosomal protein L34 | -0.0171482 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0168589 |
| TFRC | transferrin receptor | -0.0168065 |
| RBM25 | RNA binding motif protein 25 | -0.0164811 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0164456 |
| RPL18 | ribosomal protein L18 | -0.016274 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0161903 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0159772 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0159499 |
| H1-0 | H1.0 linker histone | -0.0159153 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0158889 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0158652 |
| SMAD3 | SMAD family member 3 | -0.015847 |
| MT1X | metallothionein 1X | -0.0155344 |
| RPS19 | ribosomal protein S19 | -0.0154582 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0152953 |
| RPL36 | ribosomal protein L36 | -0.0152588 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0150314 |
| MT1E | metallothionein 1E | -0.0149579 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0149228 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0148767 |
| OSMR | oncostatin M receptor | -0.014801 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0147818 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0144725 |
| TJP1 | tight junction protein 1 | -0.0144353 |
| CAVIN1 | caveolae associated protein 1 | -0.0144119 |
| RUNX1 | runt-related transcription factor 1 | -0.0143723 |
| RPL7 | ribosomal protein L7 | -0.0143546 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0141467 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0139979 |
| S100A10 | S100 calcium binding protein A10 | -0.0139551 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0137947 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0136959 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0134508 |
| RPL6 | ribosomal protein L6 | -0.0133849 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0133298 |
| RIGI | RNA sensor RIG-I | -0.0128471 |
| QKI | QKI, KH domain containing, RNA binding | -0.0127306 |
| RPLP2 | ribosomal protein, large, P2 | -0.0127239 |
| S100A9 | S100 calcium binding protein A9 | -0.0127025 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0126777 |
| ATXN2L | ataxin 2-like | -0.0126247 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0126096 |
| SVIL | supervillin | -0.0125939 |
| RPS20 | ribosomal protein S20 | -0.0125823 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0125267 |
| CDCP1 | CUB domain containing protein 1 | -0.0124432 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0124316 |
