| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vandetanib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.153997 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.141591 |
| GOLGA4 | golgin A4 | 0.108076 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0977009 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0784073 |
| OGA | O-GlcNAcase | 0.0574697 |
| CANX | calnexin | 0.0547172 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0529429 |
| ATP13A3 | ATPase type 13A3 | 0.0524781 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0524658 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0511794 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0499679 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0497104 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0495045 |
| SRP54 | signal recognition particle 54kDa | 0.0491702 |
| PCBP2 | poly(rC) binding protein 2 | 0.0491194 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0483537 |
| LMAN1 | lectin, mannose-binding, 1 | 0.046964 |
| FAM13A | family with sequence similarity 13, member A | 0.0466146 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0461115 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0459375 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0459108 |
| USP34 | ubiquitin specific peptidase 34 | 0.0457214 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0456548 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0434073 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0421008 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0407848 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0403365 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.040026 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0391841 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0383113 |
| ZNF292 | zinc finger protein 292 | 0.0368439 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0366859 |
| SPAG9 | sperm associated antigen 9 | 0.0361823 |
| SMAD3 | SMAD family member 3 | 0.0358717 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0356619 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0347039 |
| COPA | coatomer protein complex, subunit alpha | 0.034644 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0340369 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0334124 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0333454 |
| SBF2 | SET binding factor 2 | 0.0329912 |
| NBAS | neuroblastoma amplified sequence | 0.0328911 |
| CD109 | CD109 molecule | 0.032083 |
| ARRDC3 | arrestin domain containing 3 | 0.0320734 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0316994 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0313096 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0311824 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0304226 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0302721 |
| CLTC | clathrin, heavy chain (Hc) | 0.0300938 |
| VMP1 | vacuole membrane protein 1 | 0.029895 |
| RBM39 | RNA binding motif protein 39 | 0.0297533 |
| NGLY1 | N-glycanase 1 | 0.0295602 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0294359 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0291869 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0290006 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0289615 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0286281 |
| RIOK3 | RIO kinase 3 | 0.0284541 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.028177 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0280156 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0276283 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0275094 |
| GLG1 | golgi glycoprotein 1 | 0.0274912 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0270566 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0269078 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0269024 |
| COG5 | component of oligomeric golgi complex 5 | 0.0264848 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0263969 |
| WDR45B | WD repeat domain 45B | 0.0263292 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0260706 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0259614 |
| MYOF | myoferlin | 0.025897 |
| KIF5B | kinesin family member 5B | 0.0258011 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0253212 |
| SCFD1 | sec1 family domain containing 1 | 0.0250917 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0249928 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0249067 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0246421 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0243826 |
| AHR | aryl hydrocarbon receptor | 0.0242025 |
| LRRC49 | leucine rich repeat containing 49 | 0.0237509 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0234686 |
| CALU | calumenin | 0.0234539 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0233791 |
| SUCO | SUN domain containing ossification factor | 0.0233413 |
| CD44 | CD44 molecule (Indian blood group) | 0.023307 |
| FLNB | filamin B, beta | 0.0233064 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0232848 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0231202 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0230575 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0229784 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0227185 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0224944 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0222748 |
| USP37 | ubiquitin specific peptidase 37 | 0.0221822 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0221316 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.022124 |
| SETD5 | SET domain containing 5 | 0.0220615 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.133882 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.113054 |
| CDH13 | cadherin 13 | -0.106423 |
| FN1 | fibronectin 1 | -0.0973098 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0922979 |
| NRG1 | neuregulin 1 | -0.0919318 |
| HMGA2 | high mobility group AT-hook 2 | -0.0793866 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0767688 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0682269 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0662944 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0629934 |
| GLCCI1 | glucocorticoid induced 1 | -0.0625369 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0587995 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0557574 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0557072 |
| MTSS1 | metastasis suppressor 1 | -0.0554213 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0541895 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0541766 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0537628 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0456848 |
| FTL | ferritin, light polypeptide | -0.0446544 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0425655 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0416015 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0415531 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0401645 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0394309 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0386385 |
| ANTXR2 | anthrax toxin receptor 2 | -0.038418 |
| CLMP | CXADR-like membrane protein | -0.0381562 |
| CDK14 | cyclin-dependent kinase 14 | -0.0381481 |
| VIM | vimentin | -0.0376691 |
| EGR1 | early growth response 1 | -0.0374709 |
| RPL35A | ribosomal protein L35a | -0.0364151 |
| IFI44L | interferon-induced protein 44-like | -0.0347437 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0344185 |
| RPL36 | ribosomal protein L36 | -0.0341067 |
| NTN4 | netrin 4 | -0.0335537 |
| GLIS3 | GLIS family zinc finger 3 | -0.033453 |
| RPS19 | ribosomal protein S19 | -0.0332913 |
| ZNF804A | zinc finger protein 804A | -0.0307475 |
| SYT1 | synaptotagmin I | -0.0306731 |
| MECOM | MDS1 and EVI1 complex locus | -0.0298694 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0293746 |
| NRP1 | neuropilin 1 | -0.0291222 |
| NAV1 | neuron navigator 1 | -0.0287648 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0285403 |
| CUX1 | cut-like homeobox 1 | -0.0284311 |
| RPLP1 | ribosomal protein, large, P1 | -0.0284036 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0281831 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0275131 |
| RAD51B | RAD51 paralog B | -0.0270302 |
| MT2A | metallothionein 2A | -0.0269962 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0265079 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0263714 |
| HMGA1 | high mobility group AT-hook 1 | -0.0262626 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0262432 |
| SEPTIN9 | septin 9 | -0.0262317 |
| WLS | wntless Wnt ligand secretion mediator | -0.0262129 |
| FAM20C | family with sequence similarity 20, member C | -0.0261645 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0261156 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0254311 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0246504 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.024561 |
| PRRX1 | paired related homeobox 1 | -0.0243403 |
| SP100 | SP100 nuclear antigen | -0.0237189 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0234947 |
| VEGFA | vascular endothelial growth factor A | -0.0234458 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0234332 |
| IL1B | interleukin 1, beta | -0.0227541 |
| AADAC | arylacetamide deacetylase | -0.0226975 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0226365 |
| RPS8 | ribosomal protein S8 | -0.022506 |
| DIAPH2 | diaphanous-related formin 2 | -0.0223931 |
| S100A6 | S100 calcium binding protein A6 | -0.0221709 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0221353 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0220682 |
| NAV3 | neuron navigator 3 | -0.0219659 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0215224 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0215008 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0214908 |
| PTK2 | protein tyrosine kinase 2 | -0.0214182 |
| ANXA10 | annexin A10 | -0.0213684 |
| OXR1 | oxidation resistance 1 | -0.0213435 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0213343 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0211229 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0209981 |
| RPL37A | ribosomal protein L37a | -0.0207075 |
| TGFB1 | transforming growth factor, beta 1 | -0.0205719 |
| RPL23 | ribosomal protein L23 | -0.0205654 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0205466 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0205249 |
| FBN1 | fibrillin 1 | -0.0205019 |
| GPC6 | glypican 6 | -0.0204674 |
| RPS6 | ribosomal protein S6 | -0.0203851 |
| ETV6 | ets variant 6 | -0.0203694 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0202335 |
| RNF213 | ring finger protein 213 | -0.0200841 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.02004 |
| HDAC4 | histone deacetylase 4 | -0.0199718 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0199344 |
