| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vandetanib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.11016 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0847072 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0837599 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0788181 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0778064 |
| HELZ | helicase with zinc finger | 0.0769977 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0749772 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.072759 |
| S100A6 | S100 calcium binding protein A6 | 0.0709112 |
| FAM13A | family with sequence similarity 13, member A | 0.0697044 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0690387 |
| RBM39 | RNA binding motif protein 39 | 0.068539 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0670036 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0640275 |
| PTGES2 | prostaglandin E synthase 2 | 0.0635073 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0601186 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0576971 |
| SET | SET nuclear proto-oncogene | 0.0571415 |
| FOXJ3 | forkhead box J3 | 0.0565607 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0559061 |
| FOSL1 | FOS-like antigen 1 | 0.0545462 |
| JUN | jun proto-oncogene | 0.0540744 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0535954 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0533118 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0527383 |
| OGA | O-GlcNAcase | 0.0515715 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0514694 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0512336 |
| COL1A2 | collagen, type I, alpha 2 | 0.0511084 |
| GNAS | GNAS complex locus | 0.051023 |
| CEP170 | centrosomal protein 170kDa | 0.0486384 |
| QKI | QKI, KH domain containing, RNA binding | 0.048041 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0479657 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.047871 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0468119 |
| FN1 | fibronectin 1 | 0.046007 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0458666 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0455567 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0455563 |
| WDR43 | WD repeat domain 43 | 0.0452588 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0451107 |
| RND3 | Rho family GTPase 3 | 0.0450183 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0448873 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0446932 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0445133 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0444715 |
| TAOK3 | TAO kinase 3 | 0.0442857 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0439772 |
| NPTN | neuroplastin | 0.0433624 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0432863 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0429206 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0424772 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0421451 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0418553 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.041575 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0415676 |
| MCL1 | myeloid cell leukemia 1 | 0.0412709 |
| MEF2A | myocyte enhancer factor 2A | 0.0411439 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.040511 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0403019 |
| ZNF292 | zinc finger protein 292 | 0.0398503 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0398043 |
| KIF1B | kinesin family member 1B | 0.0397054 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0390809 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.038941 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.0388865 |
| PKN2 | protein kinase N2 | 0.0387277 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.03871 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0386564 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0384467 |
| SIK3 | SIK family kinase 3 | 0.0379507 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0377899 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0376205 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0372495 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.037239 |
| CDC42SE2 | CDC42 small effector 2 | 0.0371457 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0370333 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0368962 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0368087 |
| DST | dystonin | 0.0363168 |
| RPL37 | ribosomal protein L37 | 0.0357306 |
| NCKAP1 | NCK-associated protein 1 | 0.0357089 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0356722 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0351244 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0350613 |
| ANXA5 | annexin A5 | 0.0348895 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0345592 |
| RASAL2 | RAS protein activator like 2 | 0.0344533 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0342778 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0341273 |
| WWOX | WW domain containing oxidoreductase | 0.0336974 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0335667 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0334907 |
| SNX14 | sorting nexin 14 | 0.0332579 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0332536 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0332112 |
| SQSTM1 | sequestosome 1 | 0.033171 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0330135 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0328573 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0327913 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.121565 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0805763 |
| VIM | vimentin | -0.0747997 |
| TXNRD1 | thioredoxin reductase 1 | -0.0660236 |
| RPL11 | ribosomal protein L11 | -0.0659984 |
| FMNL2 | formin-like 2 | -0.0645181 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0641083 |
| HLA-B | major histocompatibility complex, class I, B | -0.0639229 |
| NBAS | neuroblastoma amplified sequence | -0.0608522 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0581576 |
| MED13L | mediator complex subunit 13-like | -0.0575449 |
| TJP1 | tight junction protein 1 | -0.0553858 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0547845 |
| PERP | PERP, TP53 apoptosis effector | -0.052084 |
| RPL19 | ribosomal protein L19 | -0.0513046 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0489006 |
| CENPF | centromere protein F, 350/400kDa | -0.0486673 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0483361 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0482071 |
| EZR | ezrin | -0.0477874 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0475299 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0471225 |
| RPS27 | ribosomal protein S27 | -0.0455581 |
| PTMA | prothymosin, alpha | -0.0451797 |
| PARD3 | par-3 family cell polarity regulator | -0.0447687 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0445666 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0432599 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0426509 |
| PRKCA | protein kinase C, alpha | -0.0425991 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0423293 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0422168 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0419929 |
| CD44 | CD44 molecule (Indian blood group) | -0.0415812 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0409308 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0406396 |
| KRT17 | keratin 17, type I | -0.0405412 |
| RPLP1 | ribosomal protein, large, P1 | -0.0402345 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0401508 |
| LSAMP | limbic system-associated membrane protein | -0.0394697 |
| LAMB3 | laminin, beta 3 | -0.0394464 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0387605 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0385587 |
| ACTG1 | actin gamma 1 | -0.0384938 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0377437 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0376361 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0376284 |
| UBE3A | ubiquitin protein ligase E3A | -0.0370918 |
| EXOC4 | exocyst complex component 4 | -0.0370787 |
| INTS6 | integrator complex subunit 6 | -0.0366185 |
| TPM4 | tropomyosin 4 | -0.0365133 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0363301 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0356476 |
| ARF4 | ADP-ribosylation factor 4 | -0.035509 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0352816 |
| RPS27A | ribosomal protein S27a | -0.0352693 |
| INHBA | inhibin, beta A | -0.0350804 |
| CUX1 | cut-like homeobox 1 | -0.035078 |
| TMSB10 | thymosin beta 10 | -0.0346472 |
| METTL15 | methyltransferase like 15 | -0.0334971 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0334835 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0332394 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.032994 |
| FLNB | filamin B, beta | -0.0329613 |
| RPS11 | ribosomal protein S11 | -0.0326939 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0326211 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0325494 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0321233 |
| RPS25 | ribosomal protein S25 | -0.0317937 |
| MAP7 | microtubule-associated protein 7 | -0.0317329 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0316724 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0316297 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0314705 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0312685 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0312636 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0312621 |
| HMGB1 | high mobility group box 1 | -0.030843 |
| MMP1 | matrix metallopeptidase 1 | -0.0307327 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0305917 |
| RPL12 | ribosomal protein L12 | -0.0305313 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.030314 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0301467 |
| PLEC | plectin | -0.030105 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0299242 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0298415 |
| CCNI | cyclin I | -0.0294562 |
| OLA1 | Obg-like ATPase 1 | -0.02933 |
| GPC6 | glypican 6 | -0.0293105 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0291789 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0290168 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0288475 |
| ZNF609 | zinc finger protein 609 | -0.0286421 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0285517 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0284727 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0284715 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0283305 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0282427 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0281892 |
| SETX | senataxin | -0.0280999 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0280134 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0277136 |
